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Nutrition: Calcium
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Total 1776 results found since Jan 2013.
Role of Na < sup > + < /sup > /K < sup > + < /sup > -ATPase in ischemic stroke: in-depth perspectives from physiology to pharmacology
J Mol Med (Berl). 2021 Nov 27. doi: 10.1007/s00109-021-02143-6. Online ahead of print.ABSTRACTNa+/K+-ATPase (NKA) is a large transmembrane protein expressed in all cells. It is well studied for its ion exchanging function, which is indispensable for the maintenance of electrochemical gradients across the plasma membrane and herein neuronal excitability. The widely recognized pump function of NKA closely depends on its unique structure features and conformational changes upon binding of specific ions. Various Na+-dependent secondary transport systems are rigorously controlled by the ionic gradients generated by NKA and are ...
Source: Molecular Medicine - November 28, 2021 Category: Molecular Biology Authors: Mengyuan Zhu Haijian Sun Lei Cao Zhiyuan Wu Bin Leng Jinsong Bian Source Type: research
Preserving mitochondrial function by inhibiting GRP75 ameliorates neuron injury under ischemic stroke
Mol Med Rep. 2022 May;25(5):165. doi: 10.3892/mmr.2022.12681. Epub 2022 Mar 16.ABSTRACTIschemic stroke is a life‑threatening disease, which is closely related to neuron damage during ischemia. Mitochondrial dysfunction is essentially involved in the pathophysiological process of ischemic stroke. Mitochondrial calcium overload contributes to the development of mitochondrial dysfunction. However, the underlying mechanisms of mitochondrial calcium overload are far from being fully revealed. In the present study, middle cerebral artery obstruction (MCAO) was performed in vivo and oxygen and glucose deprivation (OGD) in vitro...
Source: Molecular Medicine - March 16, 2022 Category: Molecular Biology Authors: Bin Wen Kai Xu Rui Huang Teng Jiang Jian Wang Jiehui Chen Juan Chen Benhong He Source Type: research
Admission Serum Calcium Level and Short-Term Mortality After Acute Ischemic Stroke: A Secondary Analysis Based on a Norwegian Retrospective Cohort
ConclusionACSC is positively associated with 30-day mortality in IS patients, and the relationship between them is linear.
Source: Frontiers in Neurology - June 15, 2022 Category: Neurology Source Type: research
Observation of Clinical Efficacy of Anisodamine and Chlorpromazine in the Treatment of Intractable Hiccup after Stroke
CONCLUSION: The combination of 2D K-L divergence and MPSO algorithm could improve the accuracy of multilayer image segmentation and CT imaging. Acupoint injection of anisodamine combined with chlorpromazine had better efficacy than the injection of anisodamine alone for the treatment of intractable hiccups after stroke, with high safety and clinical promotion value.PMID:35915796 | PMC:PMC9338746 | DOI:10.1155/2022/6563193
Source: Biomed Res - August 2, 2022 Category: Research Authors: Jing Wang Qinghua Zhu Shuyan Zhang Lisha Wen Li Wang Source Type: research
Retinoic Acid Prevents the Neuronal Damage Through the Regulation of Parvalbumin in an Ischemic Stroke Model
In conclusion, retinoic acid contributes to the preservation of neurons from ischemic stroke by controlling parvalbumin expression and apoptosis-related proteins.PMID:36245066 | DOI:10.1007/s11064-022-03769-9
Source: Neurochemical Research - October 16, 2022 Category: Neuroscience Authors: Ju-Bin Kang Dong-Ju Park Phil-Ok Koh Source Type: research
MAGT1 Deficiency Dysregulates Platelet Cation Homeostasis and Accelerates Arterial Thrombosis and Ischemic Stroke in Mice
CONCLUSIONS: These results suggest that MAGT1 and TRPC6 are functionally linked. Therefore, deficiency or impaired functionality of MAGT1 could be a potential risk factor for arterial thrombosis and stroke.PMID:37381987 | DOI:10.1161/ATVBAHA.122.318115
Source: Arteriosclerosis, Thrombosis and Vascular Biology - June 29, 2023 Category: Cardiology Authors: Sanjeev Kiran Gotru Elmina Mammadova-Bach Georgios Sogkas Michael K Schuhmann Karen Schmitt Peter Kraft Sabine Herterich Medina Mamtimin Akif Pinarci Sarah Beck Simon Stritt Han Chao Pengxuan Ren Jean-No ël Freund Christian Klemann Felix C Ringshausen Jo Source Type: research
