Post-prandial Remnant Lipoprotein Metabolism in Sitosterolemia.
CONCLUSIONS: Post-prandial lipoprotein metabolism in sitosterolemia appeared to be impaired, leading to their elevation in serum sterol levels. (UMIN Clinical Trials Registry number, UMIN000020330). PMID: 29998912 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - July 14, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Pathophysiology of Diabetic Dyslipidemia.
Authors: Hirano T Abstract Accumulating clinical evidence has suggested serum triglyceride (TG) is a leading predictor of atherosclerotic cardiovascular disease, comparable to low-density lipoprotein (LDL)-cholesterol (C) in populations with type 2 diabetes, which exceeds the predictive power of hemoglobinA1c. Atherogenic dyslipidemia in diabetes consists of elevated serum concentrations of TG-rich lipoproteins (TRLs), a high prevalence of small dense low-density lipoprotein (LDL), and low concentrations of cholesterol-rich high-density lipoprotein (HDL)2-C. A central lipoprotein abnormality is an increase in large...
Source: Journal of Atherosclerosis and Thrombosis - July 14, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

GLP-1 Receptor Agonist Exendin-4 Attenuates NR4A Orphan Nuclear Receptor NOR1 Expression in Vascular Smooth Muscle Cells.
CONCLUSION: Ex-4 attenuates neointima formation after vascular injury and VSMC proliferation possibly by inhibiting NOR1 expression. PMID: 29962378 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - July 4, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Association between Subclinical Atherosclerosis Markers and the Level of Accumulated Advanced Glycation End-Products in the Skin of Patients with Diabetes.
CONCLUSIONS: Skin AF was independently associated with FMD as an indicator of endothelial dysfunction, and can be utilized as a screening marker of atherosclerosis in Japanese patients with DM. PMID: 29962379 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - July 4, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Clinical and Economic Analysis of Lipid Goal Attainments in Chinese Patients with Acute Coronary Syndrome Who Received Post-Percutaneous Coronary Intervention.
CONCLUSIONS: Lowering LDL-C to achieve the guideline-recommended target levels for post-PCI ACS patients may lead to fewer cardiovascular events, but it may not necessarily lead to economic benefits within one year of follow-up. PMID: 29962381 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - July 4, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

A Compound Heterozygous Mutation of Lipase Maturation Factor 1 is Responsible for Hypertriglyceridemia of a Patient.
CONCLUSION: A compound heterozygous mutation of LMF1 was identified in the presenting patient with severe HTG. These findings expand on the spectrum of LMF1 mutations and contribute to the genetic diagnosis and counseling of families with HTG. PMID: 29910226 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - June 20, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Novel Approaches for the Treatment of Familial Hypercholesterolemia: Current Status and Future Challenges.
Authors: Jiang L, Wang LY, Cheng XS Abstract Familial hypercholesterolemia (FH) is an autosomal-dominant disorder that is characterized by high plasma low-density lipoprotein cholesterol (LDL-c) levels and an increased risk of cardiovascular disease. Despite the use of high-dose statins and the recent addition of proprotein convertase subtilisin/kexin type 9 inhibitors as a treatment option, many patients with homozygous FH fail to achieve optimal reductions of LDL-c levels. Gene therapy has become one of the most promising research directions for contemporary life sciences and is a potential treatment option for F...
Source: Journal of Atherosclerosis and Thrombosis - June 15, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Dietary Intake of Energy and Nutrients from Breakfast and Risk of Stroke in The Japanese Population: The Circulatory Risk in Communities Study (CIRCS).
CONCLUSIONS: A higher intake of energy from breakfast, primarily saturated or monounsaturated fat, was associated with a reduced risk of intracerebral hemorrhage in Japanese men. PMID: 29899172 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - June 15, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Statement for Appropriate Clinical Use of PCSK9 Inhibitors.
Authors: Nohara A, Ohmura H, Okazaki H, Ogura M, Kitagawa K, Koseki M, Sato K, Tsukamoto K, Yamashita S, Japan Atherosclerosis Society Working Group on Statement for Appropriate Use of PCSK9 Inhibitors PMID: 29899173 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - June 15, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Dietary Intake during 56 Weeks of a Low-Fat Diet for Lomitapide Treatment in Japanese Patients with Homozygous Familial Hypercholesterolemia.
CONCLUSION: HoFH patients can adhere to low-fat diets with ongoing dietary counseling. Instructions about intakes of energy, fatty acids and fat-soluble vitamins, as well as periodic evaluations of nutritional status, are necessary. PMID: 29899183 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - June 15, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

The Relationship of Dietary Cholesterol with Serum Low-Density Lipoprotein Cholesterol and Confounding by Reverse Causality: The INTERLIPID Study.
CONCLUSIONS: In men who were nonemployed and less educated, a higher intake of dietary cholesterol was associated with elevated concentrations of serum LDL-C, whereas an inverse association was observed in men who were employed and more educated. PMID: 29887537 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - June 13, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Circulating Sulfatide, A Novel Biomarker for ST-Segment Elevation Myocardial Infarction.
CONCLUSIONS: Elevated serum sulfatides level positively correlate with in-hospital death and complications (TVR and MACE) in STEMI patients. PMID: 29887538 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - June 13, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Thrombus Formation and Propagation in the Onset of Cardiovascular Events.
Authors: Asada Y, Yamashita A, Sato Y, Hatakeyama K Abstract Ischemic cardiovascular disease is a major cause of morbidity and mortality worldwide and thrombus formation on disrupted atherosclerotic plaques is considered to trigger its onset. Although the activation of platelets and coagulation pathways has been investigated intensively, the mechanisms of thrombus formation on disrupted plaques have not been understood in detail. Platelets are thought to play a central role in the formation of arterial thrombus because of rapid flow conditions; however, thrombus that develops on disrupted plaques consistently inclu...
Source: Journal of Atherosclerosis and Thrombosis - June 13, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Clinical and Imaging Characteristics of Cerebral Infarction in Patients with Nonvalvular Atrial Fibrillation Combined with Cerebral Artery Stenosis.
CONCLUSIONS: Advanced age, hypertension, and stroke/TIA were increased in patients with cerebral infarction with nonvalvular atrial fibrillation combined with cerebral artery stenosis. PMID: 29877196 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - June 8, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Guidelines for Diagnosis and Treatment of Familial Hypercholesterolemia 2017.
Authors: Harada-Shiba M, Arai H, Ishigaki Y, Ishibashi S, Okamura T, Ogura M, Dobashi K, Nohara A, Bujo H, Miyauchi K, Yamashita S, Yokote K, Working Group by Japan Atherosclerosis Society for Making Guidance of Familial Hypercholesterolemia Abstract Statement1. Familial hypercholesterolemia (FH) is an autosomal hereditary disease with the 3 major clinical features of hyper-LDL-cholesterolemia, premature coronary artery disease and tendon and skin xanthomas. As there is a considerably high risk of coronary artery disease, in addition to early diagnosis and intensive treatment, family screening (cascade screening) i...
Source: Journal of Atherosclerosis and Thrombosis - June 8, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Beneficial Effect of Retuning to "Japan Diet" for the Japanese.
Beneficial Effect of Retuning to "Japan Diet" for the Japanese. J Atheroscler Thromb. 2018 Jun 02;: Authors: Yokoyama S PMID: 29863036 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - June 5, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Neopterin as a Marker of In-Stent Restenosis: to have or have not.
Authors: Nishihira K PMID: 29794395 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 29, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

The Effects of Long-Term Dietary Therapy on Patients with Hypertriglyceridemia.
CONCLUSION: This study demonstrated a decrease in serum TG level after 12 months of dietary therapy similar to drug therapy, which suggests that it is an effective treatment for hypertriglyceridemia, and heightened awareness should be made to encourage its use.The clinical trial registration number: UMIN000028860. PMID: 29794409 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 29, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Relationship between CCL22 Expression by Vascular Smooth Muscle Cells and Macrophage Histamine Receptors in Atherosclerosis.
CONCLUSION: The expression of M1- or M2-like macrophages in atherosclerosis were observed to be dependent on the distribution of VSMCs owing to differences in causal stimuli and the switching of histamine receptors via Th1 or Th2 cytokines. These results suggest that CCL22 may control atherosclerosis. PMID: 29794410 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 29, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Validity of a Novel Method for Estimating Low-Density Lipoprotein Cholesterol Levels in Cardiovascular Disease Patients Treated with Statins.
CONCLUSIONS: In Japanese patients with CVD treated with statins, LDL-C level estimated by this novel method might be more accurate than those estimated using the Friedewald equation for LDL-C levels <70 mg/dL. PMID: 29794412 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 29, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Cultural Barriers in the Treatment of Dyslipidemia: A Survey of Japanese Physician Attitudes.
CONCLUSIONS: Awareness of target values for lipid management and of adverse reactions to drug therapy appears to vary somewhat depending on the participant's medical specialty. We also found that FH is probably underdiagnosed in Japan today. Further educations on proper diagnosis and management of dyslipidemia are required for physicians who are not specialized in cardiovascular health. PMID: 29780067 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 22, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Prognostic Utility of Indoxyl Sulfate for Patients with Acute Coronary Syndrome.
CONCLUSIONS: The assessment of serum IS level has prognostic utility for the management of ACS. PMID: 29780075 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 22, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Noninvasive Assessment of Arterial Stiffness Using Oscillometric Methods: baPWV, CAVI, API, and AVI.
Authors: Miyata M PMID: 29769454 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 18, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Tenascin C: A Potential Biomarker for Predicting the Severity of Coronary Atherosclerosis.
CONCLUSION: A significant relationship was found between the Gensini score and serum TNC level. TNC levels can be considered in risk assessments for CAD before angiography. PMID: 29769455 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 18, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

MiR-140-3p is Involved in In-Stent Restenosis by Targeting C-Myb and BCL-2 in Peripheral Artery Disease.
CONCLUSIONS: The result suggests that miR-140-3p regulates ASMC function via targeting C-Myb and BCL-2 in the process of ISR in PAD. The novel findings may offer a hopeful therapeutic target for human PAD. PMID: 29760303 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 17, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Response of Lipids and Lipoproteins to Regular Aquatic Endurance Exercise: A Meta-Analysis of Randomized Controlled Trials.
CONCLUSIONS: Aquatic endurance exercise improved the lipid and lipoprotein levels and benefited women, middle-aged subjects, and patients with dyslipidemia in particular. PMID: 29743386 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 12, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Venous Thromboembolism Risk Stratification: The Missing Link In Hospitalized Patients.
Authors: Al-Ogaili A, Quintero LD, Adum JPS, Fuentes HE, Caprini J PMID: 29731505 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 9, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Future Perspectives for Management of Stage A Heart Failure.
This article reviews the importance of the assessment of subclinical LV dysfunction in Stage A HF patients by means of GLS, and its current potential to prevent progression to later stage HF. PMID: 29731506 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 9, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Comprehensive Assessment of Polyvascular Atherosclerosis.
Authors: Nakanishi R, Ikeda T PMID: 29709993 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - May 2, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Associations of Common Genetic Variants on IL-17 Genes and Carotid Intima-Media Thickness.
CONCLUSIONS: We first correlated cIMT, a preclinical clinical cardiovascular marker, with IL-17RC, the key molecule in the IL-17 signaling pathway. Our results indicated that IL-17RC may play critical role in the development of atherosclerotic diseases. PMID: 29695654 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - April 28, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Association of Age and Size of Carotid Artery Intraplaque Hemorrhage and Minor Fibrous Cap Disruption: A High Resolution Magnetic Resonance Imaging Study.
CONCLUSION: The volume of fresh IPH is independently associated with MFCD in carotid plaques, suggesting that integrity of fibrous cap may change with different age and size of IPH. PMID: 29669957 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - April 21, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Japan Diet Intake Changes Serum Phospholipid Fatty Acid Compositions in Middle-Aged Men: A Pilot Study.
CONCLUSIONS: The Japan Diet is effective for changing the fatty acids to an anti-atherosclerotic profile.The clinical trial registration number: UMIN000020639. PMID: 29643271 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - April 15, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Relationship between Long Interspersed Nuclear Element-1 DNA Methylation in Leukocytes and Dyslipidemia in the Japanese General Population.
CONCLUSION: LINE-1 DNA hypermethylation in leukocytes was associated with CVD risk profiles: high LDLC, high LDL/HDL ratio, and the degree of abnormal lipid metabolism. PMID: 29628482 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - April 11, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Efficacy and Safety of Pemafibrate Versus Fenofibrate in Patients with High Triglyceride and Low HDL Cholesterol Levels: A Multicenter, Placebo-Controlled, Double-Blind, Randomized Trial.
CONCLUSIONS: The favorable safety profile of pemafibrate, with fewer adverse effects on kidney/liver-related laboratory tests and fewer AEs/ADRs, including those leading to treatment discontinuation, over fenofibrate 200 mg/day may justify the use of this novel and potent treatment option for reducing TG levels in a broader range of patients. PMID: 29628483 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - April 11, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Sweet Preference Associated with the Risk of Hypercholesterolemia Among Middle-Aged Women in Korea.
CONCLUSION: Our results suggested that preference for sweet taste may increase the consumption of sugar products and sweet drinks, which is partially linked to the risk of hypercholesterolemia and hyper-LDL cholesterolemia in Korean middle-aged women. PMID: 29618672 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - April 7, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Interleukin-6 Level among Shift and Night Workers in Japan: Cross-Sectional Analysis of the J-HOPE Study.
CONCLUSION: The present study revealed that only night shift work is significantly associated with high levels of IL-6 in Japanese workers. These observations help us understand the mechanism for the association between work schedule and CVD onset. PMID: 29593172 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - March 30, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Neopterin and Cardiovascular Events Following Coronary Stent Implantation in Patients with Stable Angina Pectoris.
CONCLUSION: These findings suggest that neopterin is associated with cardiovascular events after coronary stent implantation in patients with SAP. However, there might be a strong association between neopterin and cardiovascular events after BMS but not after DES in these patients. PMID: 29593175 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - March 30, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Accelerated Atherogenicity in Tangier Disease.
We report a case of Tangier disease with Leriche syndrome and bleeding tendency. In this male patient, nasal hemorrhage had been observed frequently throughout childhood. At 46 years old, he experienced effort angina, and coronary angiography demonstrated 75% stenosis in the right coronary artery. Orange-colored tonsils, mild hepatosplenomegaly and very low levels of serum high-density lipoprotein cholesterol (HDL-C) were observed, and the patient was diagnosed with Tangier disease. At 52 years old, effort angina recurred. Coronary angiography revealed 75% stenosis of the left main trunk, left anterior descending, and righ...
Source: Journal of Atherosclerosis and Thrombosis - March 23, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

The Linkage Between Low Pulmonary Function and Subclinical Cerebrovascular Lesion in Never-Smokers.
Authors: Shibata Y PMID: 29553065 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - March 20, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Physical Exercise Reduces Cytotoxicity and Up-Regulates Nrf2 and UPR Expression in Circulating Cells of Peripheral Artery Disease Patients: An Hypoxic Adaptation?
CONCLUSIONS: Treadmill training in PAD patients through UPR and Nrf2 up-regulation may trigger hypoxic adaptation similar to conditioning, thus modifying cell survival. PMID: 29540636 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - March 16, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Assessment of the Risk of Venous Thromboembolism in Medical Inpatients using the Padua Prediction Score and Caprini Risk Assessment Model.
CONCLUSIONS: Both the PPS and Caprini RAM can be used to stratify the VTE risk in medical inpatients effectively, but the Caprini RAM may be considered as the first choice in a general hospital because of its incorporation of comprehensive risk factors, higher sensitivity to identify patients who may benefit from prophylaxis, and potential for prediction of mortality. PMID: 29540637 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - March 16, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Assessing Impact of High-Dose Pitavastatin on Carotid Artery Elasticity with Speckle-Tracking Strain Imaging.
CONCLUSIONS: Short-term treatment with high-dose pitavastatin improved carotid artery elasticity measured by speckle-tracking method, but not conventional parameters by B-mode ultrasound. Speckle-tracking-based measurements may allow the early noninvasive assessment of statin effects on vascular function in hypercholesterolemic patients. PMID: 29515050 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - March 9, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Circulating Oxidized Low-Density Lipoprotein Levels Independently Predict 10-Year Progression of Subclinical Carotid Atherosclerosis: A Community-Based Cohort Study.
CONCLUSION: This study demonstrates that serum ox-LDL levels predict 10-year progression of subclinical atherosclerosis. Moreover, this effect is independent of the cholesterol content, the number, and the size of LDL particles. PMID: 29515051 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - March 9, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Investigation of Obstructive Sleep Apnea Using Portable Monitors and Health Check Data in Japanese Drivers.
CONCLUSION: Notably, drivers with undiagnosed OSA exist. In these subjects, AHI was related to obesity, hypertension, and diabetes. For the early diagnosis and intervention of OSA, BMI, blood pressure, and HbA1c measurements may be helpful, particularly for drivers. Furthermore, when performing an objective assessment of the suspected OSA, evaluating these parameters during routine medical check-ups may be useful and feasible in the detection of drivers with latent OSA. PMID: 29503410 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - March 6, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Low Levels of Plasma Osteoglycin in Patients with Complex Coronary Lesions.
CONCLUSION: Although plasma osteoglycin levels were high in patients with CAD, they did not correlate with the severity of CAD and were not an independent factor for CAD. Notably, osteoglycin levels were low in patients with complex lesions and were a factor for complex lesions, suggesting that osteoglycin plays a role in coronary plaque stabilization. PMID: 29503411 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - March 6, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Evaluation of Lenticulostriate Arteries Changes by 7 T Magnetic Resonance Angiography in Type 2 Diabetes.
CONCLUSION: In spite of the prevalence of SVD being similar, structural changes and decreased signal intensity of LSA were highly detected in diabetic subjects compared with non-diabetic controls, suggesting that 7 T MRA enables us to determine LSA impairment prior to the development of SVD. Early detection of LSA impairment allows us earlier interventions aimed at the prevention of atherosclerotic events. PMID: 29503412 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - March 6, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Pathophysiological Significance of Velocity-Based Microvascular Resistance at Maximal Hyperemia in Peripheral Artery Disease.
CONCLUSION: EVT for SFA stenosis improved FFR and VFR comprehensively, with no apparent change in h-MR. However, high h-MR before EVT may play a predictive role for limb perfusion improvement associated with h-MR reduction after EVT. PMID: 29491227 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - March 2, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Specific Health Guidance, the Nationwide Lifestyle Intervention Program Targeting Metabolic Syndrome, Seems to be Successful in Japan.
Authors: Matsuzawa Y PMID: 29467342 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - February 26, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

How Should We Effectively Support Smoking Cessation at Health Checkup Opportunity and Induce More Quitters.
Authors: Iida M PMID: 29467343 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - February 26, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Reduced Lung Function and Cerebral Small Vessel Disease in Japanese Men: the Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA).
CONCLUSION: In a community-based sample of Japanese men, we found an association between reduced lung function and WMLs and lacunar infarcts in never smokers. PMID: 29459517 [PubMed - as supplied by publisher] (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - February 21, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research