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Physicians' Perspective Toward Hypertensive Disorders of Pregnancy and Future Cardiovascular Diseases in Japan
CONCLUSION: We found that physicians had a high level of knowledge about HDP and the importance of reproductive information. However, the manner of obtaining information, including the target population, differed depending on the subspeciality. In the future, effective interventions for women with a history of HDP need to be developed in order to encourage physicians to obtain reproductive information to prevent CVD.PMID:38296534 | DOI:10.5551/jat.64453 (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - January 31, 2024 Category: Cardiology Authors: Makiko Egawa Masami Ikeda Naoyuki Miyasaka Mariko Harada-Shiba Masayuki Yoshida Source Type: research

Relationships of Weight Change from 20 Years of Age with the Risks of All-Cause and Cardiovascular Mortality in Patients with Chronic Kidney Disease
CONCLUSION: Weight loss from 20 years of age was found to be associated with higher risks of all-cause and cardiovascular mortalities in patients with CKD.PMID:38267049 | DOI:10.5551/jat.64571 (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - January 24, 2024 Category: Cardiology Authors: Kazuhiro Okamura Shigeru Tanaka Hiromasa Kitamura Hiroto Hiyamuta Kazuhiko Tsuruya Toshiaki Nakano Takanari Kitazono Source Type: research

Ankle Brachial Index: An Easy and First-Choice Screening Marker of Peripheral Artery Disease and Physical Function
J Atheroscler Thromb. 2024 Jan 17. doi: 10.5551/jat.ED252. Online ahead of print.NO ABSTRACTPMID:38233205 | DOI:10.5551/jat.ED252 (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - January 17, 2024 Category: Cardiology Authors: Kazunori Horie Source Type: research

Cigarette Smoking and Atherosclerotic Cardiovascular Disease
J Atheroscler Thromb. 2024 Jan 14. doi: 10.5551/jat.RV22015. Online ahead of print.ABSTRACTThe detrimental effects of cigarette smoking on cardiovascular health, particularly atherosclerosis and thrombosis, are well established, and more detailed mechanisms continue to emerge. As the fundamental pathophysiology of the adverse effects of smoking, endothelial dysfunction, inflammation, and thrombosis are considered to be particularly important. Cigarette smoke induces endothelial dysfunction, leading to impaired vascular dilation and hemostasis regulation. Factors contributing to endothelial dysfunction include reduced bioav...
Source: Journal of Atherosclerosis and Thrombosis - January 14, 2024 Category: Cardiology Authors: Mari Ishida Chiemi Sakai Yusuke Kobayashi Takafumi Ishida Source Type: research

Antihypertensive Drugs Affect the Association of Systolic Blood Pressure Variability with Outcomes in Patients with Acute Stroke who had Successful Recanalization after Endovascular Treatment
CONCLUSION: In the anterior circulation of patients with AIS-LVO who had successful recanalization after EVT, the utilization of antihypertensive drugs may have some impact on the relationship between SBPV and clinical outcomes.PMID:38220185 | DOI:10.5551/jat.64637 (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - January 14, 2024 Category: Cardiology Authors: Jing Li Bai-Jun Liu Ying-Jia Wang Yu Cui Hui-Sheng Chen Source Type: research

Efficacy, Safety, and Pharmacokinetics of Inclisiran in Japanese Patients: Results from ORION-15
CONCLUSION: Inclisiran sodium 100, 200, and 300 mg demonstrated clinically meaningful and statistically significant LDL-C and PCSK9 reductions at Day 180, which were consistent over 12 months. Inclisiran was effective and well tolerated in Japanese patients with hypercholesterolemia, including HeFH.PMID:38220186 | DOI:10.5551/jat.64454 (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - January 14, 2024 Category: Cardiology Authors: Shizuya Yamashita Arihiro Kiyosue Pierre Maheux Jorge Mena-Madrazo Anastasia Lesogor Qing Shao Yuko Tamaki Hidekazu Nakamura Mizuki Akahori Kouji Kajinami Source Type: research

Effect of the Xanthine Oxidase Inhibitor, Febuxostat, on WBC Count in Asymptomatic Hyperuricemia: Subanalysis of the Randomized PRIZE Study
CONCLUSIONS: Febuxostat therapy for 24 months modestly, but significantly, decreased WBC count in patients with asymptomatic hyperuricemia. This might potentially reflect a modest anti-inflammatory action of febuxostat in clinical settings.PMID:38220209 | DOI:10.5551/jat.64574 (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - January 14, 2024 Category: Cardiology Authors: Mitsuhide Takeshita Atsushi Tanaka Hisako Yoshida Ikuko Nakamura Yoshisato Shibata Shiro Hata Akifumi Kushiyama Masaaki Okutsu Tomoko Ishizu Koichi Node Source Type: research

Validation of Estimated Small Dense Low-Density Lipoprotein Cholesterol Concentration in a Japanese General Population
CONCLUSIONS: sdLDL-C level estimated by Sampson's equation can be used instead of measured sdLDL-C level in general practice. By building multiple machine learning models of artificial intelligence, a more accurate and practical estimation of sdLDL-C level might be possible.PMID:38171805 | DOI:10.5551/jat.64578 (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - January 3, 2024 Category: Cardiology Authors: Keisuke Endo Ryo Kobayashi Makito Tanaka Marenao Tanaka Yukinori Akiyama Tatsuya Sato Itaru Hosaka Kei Nakata Masayuki Koyama Hirofumi Ohnishi Satoshi Takahashi Masato Furuhashi Source Type: research

Remnant Cholesterol is More Strongly Associated with Arterial Stiffness than Traditional Lipids and Lipid Ratios in the General Chinese Population
CONCLUSION: In conclusion, compared with traditional lipids and lipid ratios, RC is more strongly associated with AS. The association between RC and AS remains significant even when TG, LDL-C, HDL-C, or non-HDL-C levels are controlled within the appropriate range.PMID:38171806 | DOI:10.5551/jat.64146 (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - January 3, 2024 Category: Cardiology Authors: Binqi Li Xin Zhou Yang Liu Yue Zhang Yiming Mu Source Type: research

Cardiovascular Risk Age Reflects Arterial Status: Middle-Aged People Showed Equivalent Arterial Stiffness to Older People in the Same Risk Category
CONCLUSIONS: In categories with the same cardiovascular risk, the arterial stiffness of participants with a higher risk factor burden (increased risk age) matched that of older participants with the rest of the risk factors at optimal levels (same chronological and risk age). These results support the guidelines on the utilization of risk age to explain heightened cardiovascular risk, particularly among individuals in middle age.PMID:38171907 | DOI:10.5551/jat.64541 (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - January 3, 2024 Category: Cardiology Authors: Lia Alves-Cabratosa Marc Elosua-Bay és Ruth Mart í-Lluch Jordi Blanch Èric Tornabell-Noguera Maria Garcia-Gil Anna Ponjoan Maria Grau Francesc Ribas-Aulinas Llu ís Zacarías-Pons Jaume Marrugat Rafel Ramos Source Type: research