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Specialty: Neurology
Condition: Alcoholism
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Total 356 results found since Jan 2013.
Recurrent Ischemic and Hemorrhagic Stroke in Cameroon: A Case-Control Study
CONCLUSION: We mapped the landscape of recurrent strokes in Cameroon. There is a need to evaluate the causes of suboptimal drug adherence rates and both the role and adherence to nonpharmacologic interventions.PMID:34221504 | PMC:PMC8221891 | DOI:10.1155/2021/9948990
Source: Neurology Research International - July 5, 2021 Category: Neurology Authors: Jaur ès Kamgang Francklin T étinou Yvan Zolo Chee Yang Tan Christian Wambo Emerancienne J N Fongang Ulrick Sidney Kanmounye Source Type: research
Progressive Ataxia and Downbeat Nystagmus in the Adult
A 63-year-old man presented with a history of vomiting, hypertension, dyslipidemia, type 2 diabetes, dilated ischemic cardiomyopathy, alcohol use, and stroke; physical examination found appendicular dysmetria with truncal ataxia and downbeat nystagmus. Brain magnetic resonance imaging revealed a hyperintensity on T2-weighted and fluid-attenuated inversion recovery sequences without reduced diffusion in the cerebellar nodule. What is your diagnosis?
Source: JAMA Neurology - May 17, 2021 Category: Neurology Source Type: research
Risk factors for early –onset seizures after stroke: A systematicreview and meta‐analysis of 18 observational studies
ConclusionsThese findings suggest that cortical involvement, intracerebral hemorrhage, and cerebral infarction with hemorrhagic transformation are important predictors and risk factors for early seizures after stroke, while the patient's gender, age, NHISS score, alcoholism, smoking, high blood pressure, diabetes, atrial fibrillation, dyslipidemia, receiving surgical treatment, and reperfusion therapy showed no association with the occurrence of early ‐onset seizures after stroke.
Source: Brain and Behavior - May 4, 2021 Category: Neurology Authors: Sitian Ma,
Xiaoxuan Fan,
Xiaoping Zhao,
Kai Wang,
Huan Wang,
Yongfeng Yang Tags: ORIGINAL RESEARCH Source Type: research
COVID-19 Associated Reversible Cerebral Vasoconstriction Syndrome Successfully Treated with Nimodipine and Aspirin
A 31-year-old sexually active, non-smoker female with a past medical history of spina-bifida and idiopathic thoracolumbar scoliosis status post hardware spinal fusion surgery five years ago presented with a one-day history of severe holocranial headaches associated with nausea and visual changes. A thorough neurological examination was intact. She complained of mild cough as well. She had a positive nasopharyngeal swab for SARS-CoV-2 on RT-PCR assay. A comprehensive drug screen including amphetamines, cocaine, nicotine, alcohol, and ecstasy as well as a pregnancy test were negative; coagulation profile was within normal limits.
Source: Journal of Stroke and Cerebrovascular Diseases - April 12, 2021 Category: Neurology Authors: Tarab Mansoor, Ali A. Alsarah, Hossein Mousavi, Javed Elyias, Tarun Girotra, Omar Hussein Tags: Case Report Source Type: research
Study of Symptomatic vs. Silent Brain Infarctions on MRI in Elderly Subjects
Brain infarctions are closely associated with future risk of stroke and dementia. Our goal was to report (i) frequency and characteristics that differentiate symptomatic vs. silent brain infarctions (SBI) on MRI and (ii) frequency and location by vascular distribution (location of stroke by major vascular territories) in a population based sample. From Mayo Clinic Study of Aging, 347 participants (≥50 years) with infarcts detected on their first MRI were included. Infarct information was identified visually on a FLAIR MRI image and a vascular territory atlas was registered to the FLAIR image data in order to identify the...
Source: Frontiers in Neurology - February 17, 2021 Category: Neurology Source Type: research
Protective Role of Low Ethanol Administration Following Ischemic Stroke via Recovery of KCC2 and p75 NTR Expression
AbstractA striking result from epidemiological studies show a correlation between low alcohol intake and lower incidence for ischemic stroke and severity of derived brain injury. Although reduced apoptosis and inflammation has been suggested to be involved, little is known about the mechanism mediating this effect in vivo. Increase in intracellular chloride concentration and derived depolarizing GABAAR-mediated transmission are common consequences following various brain injuries and are caused by the abnormal expression levels of the chloride cotransporters NKCC1 and KCC2. Downstream pro-apoptotic signaling through p75NTR...
Source: Molecular Neurobiology - February 11, 2021 Category: Neurology Source Type: research
Seizures and epilepsy after intracerebral hemorrhage: an update
AbstractSeizures are common after intracerebral hemorrhage, occurring in 6 –15% of the patients, mostly in the first 72 h. Their incidence reaches 30% when subclinical or non-convulsive seizures are diagnosed by continuous electroencephalogram. Several risk factors for seizures have been described including cortical location of intracerebral hemorrhage, presence of intr aventricular hemorrhage, total hemorrhage volume, and history of alcohol abuse. Seizures after intracerebral hemorrhage may theoretically be harmful as they can lead to sudden blood pressure fluctuations, increased intracranial pressure, and neuronal inj...
Source: Journal of Neurology - February 10, 2021 Category: Neurology Source Type: research
A Sharp Decline in Burden of Stroke in Rural China During COVID-19 Pandemic
This study aimed to explore trends in the burden from stroke associated with home quarantine during the COVID-19 pandemic. Patients with a first-ever stroke registered between January 1 and April 20 from 2010 to 2020 were included in this study. We compared the incidence and the rates of mortality, hospitalization, and diagnosis by neuroimaging for first-ever stroke among a low-income population in rural China during the study periods. Overall, 377 first-ever stroke patients were analyzed in this study period; men accounted for 59.2%. Compared with 2019, the incidence of first-ever stroke was 73.5% lower in 2020 (P < 0....
Source: Frontiers in Neurology - January 25, 2021 Category: Neurology Source Type: research
Antihistamines as a common cause of new-onset seizures: a single-center observational study
ConclusionIn our population, antihistamine accounted for the highest proportion of drug-induced seizures. Considering that antihistamines are widely used as over-the-counter drugs around the world, they should be considered a possible cause of new-onset seizures.
Source: Neurological Sciences - January 12, 2021 Category: Neurology Source Type: research
Neurotoxicology Syndromes Associated with Drugs of Abuse
This article focuses on the epidemiology, pharmacology, and complications associated wit h commonly used recreational drugs, including opioids, alcohol, marijuana, cocaine, and hallucinogens.
Source: Neurologic Clinics - October 9, 2020 Category: Neurology Authors: Rachel A. Caplan, Jonah P. Zuflacht, Jed A. Barash, Corey R. Fehnel Source Type: research
Vascular Events, Vascular Disease and Vascular Risk Factors —Strongly Intertwined with COVID-19
AbstractPurpose of reviewTo elucidate the intertwining of vascular events, vascular disease and vascular risk factors and COVID-19.Recent findingsStrokes are a leading cause of disability and death worldwide. Vascular risk factors are important drivers of strokes. There are unmodifiable vascular risk factors such as age and ethnicity and modifiable vascular risk factors. According to the INTERSTROKE study, the 10 most frequent modifiable vascular risk factors are arterial hypertension, physical inactivity, overweight, dyslipidaemia, smoking, unhealthy diet, cardiac pathologies, diabetes mellitus, stress/depression and over...
Source: Current Treatment Options in Neurology - October 8, 2020 Category: Neurology Source Type: research
Filling the gaps on stroke research: focus on inflammation and immunity.
Abstract
For the last two decades, researchers have placed hopes in a new era in which a combination of reperfusion and neuroprotection would revolutionize the treatment of stroke. Nevertheless, despite the thousands of papers available in the literature showing positive results in preclinical stroke models, randomized clinical trials have failed to show efficacy. It seems clear now that the existing data obtained in preclinical research have depicted an incomplete picture of stroke pathophysiology. In order to ameliorate bench-to-bed translation, in this review we first describe the main actors on stroke inflamma...
Source: Brain, Behavior, and Immunity - October 1, 2020 Category: Neurology Authors: Levard D, Buendia I, Lanquetin A, Glavan M, Vivien D, Rubio M Tags: Brain Behav Immun Source Type: research
Readmissions for Depression and Suicide Attempt following Stroke and Myocardial Infarction
Conclusions: IS was associated with greater hazard of readmission due to depression compared to MI. Patients with a history of depression, smoking, and alcoholism were more likely to be readmitted with depression, while advanced age and discharge home were protective. It is unclear to what extent differences in type of ischemic tissue damage and disability contribute, and further investigation is warranted.Cerebrovasc Dis Extra 2020;10:94 –104
Source: Cerebrovascular Diseases Extra - August 27, 2020 Category: Neurology Source Type: research
Interaction between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and environment with susceptibility to ischemic stroke in Chinese population
Conclusions: The rs4846049-A and rs3737967-T, gene–environment interaction between rs1764391 and rs918592, gene–environment interaction between rs4846049 and alcohol drinking were all associated with increased IS risk.
Source: Annals of Indian Academy of Neurology - August 20, 2020 Category: Neurology Authors: Xing-Zhen Zheng Xiao-Lin Bian Zhe-Hong Sun Hai-Dong Wang Source Type: research
