Glucometabolic-Related Genes as Diagnostic Biomarkers and Therapeutic Targets for Alzheimer's Disease and Type 2 Diabetes Mellitus: A Bioinformatics Analysis
CONCLUSION: Our rigorous research sheds light on the molecular interconnections between AD and T2DM from a glucometabolic perspective, revealing new opportunities for pharmacological innovation and therapeutic approaches. This study appears to be the first to extensively investigate glucometabolic-associated DEGs and key genes in both AD and T2DM, utilizing multiple datasets. These insights are set to enhance our understanding of the complex pathophysiology underlying these widespread chronic diseases.PMID:38595695 | PMC:PMC11003797 | DOI:10.1155/2024/5200222 (Source: Neurology Research International)
Source: Neurology Research International - April 10, 2024 Category: Neurology Authors: Shuo Liu He Chen Xiao-Dong He Xiao-Ou Yang Source Type: research
Sleep Disorders and Fatigue among Patients with MS: The Role of Depression, Stress, and Anxiety
This study aimed to examine the role of depression, stress, and anxiety in predicting sleep disorders and fatigue among patients with MS. Employing a cross-sectional descriptive-correlational design, the study involved a sample size of 252 participants selected through purposive sampling based on inclusion and exclusion criteria. We utilized a demographic information questionnaire along with the Mini-Sleep Questionnaire (MSQ), Fatigue Severity Scale (FSS), and Depression, Anxiety, and Stress Scale (DASS-21) to collect data and analyzed them applying SPSS22, incorporating statistical measures including Pearson correlation a...
Source: Neurology Research International - February 7, 2024 Category: Neurology Authors: Nassim Zekibakhsh Mohammadi Amir Sam Kianimoghadam Niloofar Mikaeili Seyedeh Samaneh Asgharian Mahdieh Jafari Abbas Masjedi-Arani Source Type: research
