The Effect of Hyperbaric Oxygen Therapy on Functional Impairments Caused by Ischemic Stroke.
Conclusions: Findings from this study support the idea of HBOT as a potential intervention following stroke. PMID: 30402285 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - November 9, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Electrochemical Skin Conductance as a Marker of Painful Oxaliplatin-Induced Peripheral Neuropathy.
Authors: Delmotte JB, Tutakhail A, Abdallah K, Reach P, D'Ussel M, Deplanque G, Beaussier H, Coudoré F Abstract Purpose: Oxaliplatin is a platinum compound widely used in gastrointestinal cancer treatment but produces dose-limiting peripheral neuropathy. New insights into oxaliplatin-induced peripheral neuropathy (OIPN) assessment are needed to detect more effectively this condition. In this context, we conducted Canaloxa study, a prospective preliminary clinical trial that aimed to investigate how Electrochemical Skin Conductance (ESC), a parameter used in small fiber neuropathy assessment, could be helpful...
Source: Neurology Research International - October 27, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Knowledge and Attitudes of Saudi Emergency Physicians toward t-PA Use in Stroke.
Conclusion: Our study detected inadequate knowledge and a negative attitude among Saudi emergency physicians toward t-PA use in acute stroke. This might negatively impact patient outcome. Therefore, we recommend developing urgent strategies to improve emergency physicians' knowledge, attitudes, and beliefs in the management of acute stroke. PMID: 30364030 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - October 27, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Prevalence and Risk Factors for Depression among Caregivers of Alzheimer's Disease Patients in Saudi Arabia.
Conclusions: Prevalence of depression among AD caregiver is high. Risk factors for depression include patients' exposure to repeated falls and prolonged stay with patients. Therefore, psychiatric care should be provided to caregivers, home safety should be maintained to avoid falls, and several persons should interchangeably provide care to AD patients. PMID: 30305962 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - October 13, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Assessment of Patients' Adherence to Antiepileptic Medications at Dessie Referral Hospital, Chronic Follow-Up, South Wollo, Amhara Region, North East Ethiopia.
Conclusion. Majority of epileptic patients in Dessie Referral Hospital was adherent to their AEDs treatment and among the determinants of adherence assessed the level of education and the side effect of drugs showed statistical significance. PMID: 30271635 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - October 4, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Retrospective Analysis of Ventriculitis in External Ventricular Drains.
Conclusions: The c-EVD with prolonged antibiotics given for the duration of drain placement is not inferior to ac-EVD with pp-abx or ac-EVD with prolonged antibiotics for prevention of ventriculitis. The c-EVD with prolonged antibiotics is superior to c-EVD with pp-abx and conventional EVD without antibiotics for prevention of ventriculitis. Selection should include considerations for antibiotic stewardship and cost effectiveness. Future studies should also utilize clinical and CSF profile criteria in addition to positive CSF cultures for identifying ventriculitis to prevent line colonization from classification as ventric...
Source: Neurology Research International - September 26, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Serotonin Reuptake Inhibitors in Obstructive Sleep Apnea: Associations in People with and without Epilepsy.
Conclusions: SRIs represent a potential treatment option for OSA and may demonstrate a more robust association with reduced OSA severity in PWE compared to PWO. PMID: 30245877 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - September 26, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Genetic Influences on Cognition in Idiopathic Parkinson's Disease.
Authors: Amer H, Shehata H, Rashed LA, Helmy H, El-Jaafary S, Sabbah A, Ibrahim W PMID: 30155299 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - August 31, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Maximizing the Survival of Amyotrophic Lateral Sclerosis Patients: Current Perspectives.
Authors: Khairoalsindi OA, Abuzinadah AR Abstract Amyotrophic lateral sclerosis is a neurodegenerative disease that leads to loss of the upper and lower motor neurons. Almost 90% of all cases occur in the sporadic form, with the rest occurring in the familial form. The disease has a poor prognosis, with only two disease-modifying drugs approved by the United States Food and Drug Administration (FDA). The approved drugs for the disease have very limited survival benefits. Edaravone is a new FDA-approved medication that may slow the disease progression by 33% in a selected subgroup of ALS patients. This paper covers ...
Source: Neurology Research International - August 31, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Prevalence of Stroke Risk Factors and Their Distribution Based on Stroke Subtypes in Gorgan: A Retrospective Hospital-Based Study-2015-2016.
Conclusion: Overall, hypertension, diabetes mellitus, and dyslipidemia were the major risk factors of stroke in Gorgan. Establishment of stroke registry (population- or hospital-based) for the province is recommended. PMID: 30147952 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - August 28, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Effect of Gravity and Task Specific Training of Elbow Extensors on Upper Extremity Function after Stroke.
Conclusions: The results of this study provide an evidence that antigravity positions can be used as a centrally presented facilitator of elbow extension. Additionally, task specific training was effective in improving upper extremity function and elbow extension range of motion. PMID: 30112205 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - August 18, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Diagnosis of Encephalopathy Based on Energies of EEG Subbands Using Discrete Wavelet Transform and Support Vector Machine.
Authors: Jacob JE, Nair GK, Iype T, Cherian A Abstract EEG analysis in the field of neurology is customarily done using frequency domain methods like fast Fourier transform. A complex biomedical signal such as EEG is best analysed using a time-frequency algorithm. Wavelet decomposition based analysis is a relatively novel area in EEG analysis and for extracting its subbands. This work aims at exploring the use of discrete wavelet transform for extracting EEG subbands in encephalopathy. The subband energies were then calculated and given as feature sets to SVM classifier for identifying cases of encephalopathy from ...
Source: Neurology Research International - August 1, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Stroke Prevalence in a Coastal Town on the Black Sea Coast in Turkey: Community Based Study.
Conclusion: The results of this study give the prevalence rate of stroke among the Turkish population living in a rural area. Due to a lack of other similar studies, it is impossible to make any data comparison. However, the results of this study help shed light on the stroke prevalence rate. PMID: 30057814 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - August 1, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

The Effects of Induction and Treatment of Intracranial Hypertension on Cerebral Autoregulation: An Experimental Study.
This study aimed to analyse cerebral autoregulation (CA) during induction and treatment of intracranial hypertension (ICH) in an experimental model. Materials and Methods: Landrace and Duroc piglets were divided into mild and severe ICH groups. Four or seven millilitres of saline solution was infused into paediatric bladder catheter inserted in the parietal lobe (balloon inflation). After 1.5 h, a 3% saline solution was infused via venous catheter, and 30 min later, the bladder catheter balloon was deflated (surgery). The cerebral static autoregulation (sCA) index was evaluated using cerebral blood flow velocities (CBF...
Source: Neurology Research International - July 28, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Neuropsychiatric Involvement in Juvenile-Onset Systemic Lupus Erythematosus.
Conclusion: The presence of headache, mood disorders, psychosis, depression, and other neuropsychological manifestations in a patient with JSLE should prompt investigations into diagnosis of the primary nervous system involvement in order to reduce mortality and morbidity. PMID: 30002929 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - July 15, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Can Chaotic Analysis of Electroencephalogram Aid the Diagnosis of Encephalopathy?
Authors: Jacob JE, Cherian A, Gopakumar K, Iype T, Yohannan DG, Divya KP Abstract Chaotic analysis is a relatively novel area in the study of physiological signals. Chaotic features of electroencephalogram have been analyzed in various disease states like epilepsy, Alzheimer's disease, sleep disorders, and depression. All these diseases have primary involvement of the brain. Our study examines the chaotic parameters in metabolic encephalopathy, where the brain functions are involved secondary to a metabolic disturbance. Our analysis clearly showed significant lower values for chaotic parameters, correlation dimensi...
Source: Neurology Research International - July 15, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Effectiveness and Adverse Effect of Intravenous Lacosamide in Nonconvulsive Status Epilepticus and Acute Repetitive Seizures in Children.
This study is registered to Thai Clinical Trials Registry (TCTR) and the trial registration number is TCTR20180508004. PMID: 29984000 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - July 11, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

The Early Outcomes of Nurse Case Management in Patients with Acute Ischemic Stroke Treated with Intravenous Recombinant Tissue Plasminogen Activator: A Prospective Randomized Controlled Trial.
Conclusion: The nurse case management should provide some benefits in the acute stroke system. Although the early benefit is demonstrated in our study, further studies are needed to ensure the long-term benefit and confirm its profit in patients with acute ischemic stroke. PMID: 29977617 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - July 8, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

The Perceived Social Stigma of People with Epilepsy with regard to the Question of Employability.
Authors: de Souza JL, Faiola AS, Miziara CSMG, de Manreza MLG Abstract Objective: To evaluate the perceived social stigma of people with epilepsy with regard to the question of employability. Methods: A structured questionnaire was given to two groups of people with chronic diseases: those with epilepsy (study group) and those with heart disease (control group). The questions concerned employability. Results: Having epilepsy was more strongly associated with higher unemployment rates (p
Source: Neurology Research International - June 6, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Depressive Symptoms in Individuals after Stroke in a Home-Based Rehabilitation Setting.
This study evaluated patients after stroke who actively participated in a home-based rehabilitation program to determine variables that correlated with depressive symptoms in this population. A retrospective review of patients who were provided rehabilitation by Community Stroke Rehabilitation Team clinicians between January 1, 2009, and September 30, 2015, was completed. Logistic regression analysis was conducted to determine which demographic and outcome variables (Functional Independence Measure [FIM™] and Reintegration to Normal Living Index [RNLI]) were independently associated with depressive symptoms, as defin...
Source: Neurology Research International - June 4, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Risk Factors Associated with Severity of Nongenetic Intellectual Disability (Mental Retardation) among Children Aged 2-18 Years Attending Kenyatta National Hospital.
Conclusion: The present study findings suggest that perinatal complications as well as postnatal insults are associated with increased risk of developing severe-profound intellectual disability, implying that this occurrence may be reduced with appropriate antenatal, perinatal, and neonatal healthcare interventions. PMID: 29850243 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - June 4, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Efficacy of High-Dose and Low-Dose Simvastatin on Vascular Oxidative Stress and Neurological Outcomes in Patient with Acute Ischemic Stroke: A Randomized, Double-Blind, Parallel, Controlled Trial.
Conclusion: High-dose simvastatin might be helpful to reduce serum sLOX-1. But no difference in clinical outcomes was found between high- and low-dose simvastatin. Further more intensive clinical trial is needed to confirm the appropriate dosage of simvastatin in patients with acute ischemic stroke. This trial is registered with ClinicalTrials.gov ID: NCT03402204. PMID: 29850244 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - June 4, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Ethnicity Influences Corpus Callosum Dimensions.
Authors: Nouri Hosseini H, Mohammadi MR, Aarabi M, Mohammadi N, Golalipour MJ Abstract Background and Objective: Corpus callosum (CC), the main white matter cable which connects two hemispheres of brain, is important in special procedures such as stereotaxic surgeries vary in size, in different populations. Determination of possible size differences in ethnical groups has special values. Patients and Methods: The size of the CC on midsagittal view was determined in 76 normal male subjects using MRI of brain hemispheres in northern Iran. The size of rostrum, body, splenium, length, and height of CC was measured ...
Source: Neurology Research International - June 4, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Effects of Number of Repetitions and Number of Hours of Shaping Practice during Constraint-Induced Movement Therapy: A Randomized Controlled Trial.
Conclusion: Number of repetitions of shaping practice significantly improved motor function, real-world arm use, and upper limb self-efficacy after stroke. Therefore, it seems to be a simple alternative for the use of number of hours. Trial Registration: This trial is registered with Pan African Clinical Trial Registry (registration number: PACTR201610001828172) (date of registration: 21/10/2016). PMID: 29808120 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - May 30, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Practice Patterns and Barriers for Intravenous Thrombolysis: A Survey of Neurologists in Saudi Arabia.
Authors: Alanazy MH, Barakeh RB, Asiri A, Edrees MF, Abuzinadah AR, Aljafen BN, Muayqil T Abstract Only a small fraction of patients with acute ischemic stroke receive intravenous thrombolysis (IVT). We sought to assess barriers and practice patterns in using IVT for acute ischemic stroke among neurologists in Saudi Arabia. An electronic survey was sent to all neurologists registered with the Saudi Commission for Health Specialties. A total of 148 (77.5%) neurologists responded. The most common reported barriers for IVT administration were delayed presentation to hospitals (82.4%) and unclear time of symptom onset ...
Source: Neurology Research International - April 19, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

The Role of Moderate Aerobic Exercise as Determined by Cardiopulmonary Exercise Testing in ALS.
Authors: Braga ACM, Pinto A, Pinto S, de Carvalho M Abstract Introduction: The efficacy of cardiopulmonary exercise testing (CPET) to determining exercise intensity has not been established in Amyotrophic Lateral Sclerosis (ALS). We studied this intervention. Methods: We included 48 ALS patients randomized in 2 groups: G1 (n = 24), exercise intensity leveled by CPET; G2 (n = 24), standard care limited by fatigue, during 6 months. ALS functional scale (ALSFRS-R) and forced vital capacity (FVC) were performed every 3 months; CPET was done at admission (T1) and 6 months later (T2). We registered oxygen uptake, car...
Source: Neurology Research International - April 19, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Seizure-Related Injuries among People with Epilepsy at the Outpatient Department of the University of Gondar Hospital, Northwest Ethiopia: Cross-Sectional Institutional-Based Study.
Conclusion: More than a quarter of the study participants experienced physical injury. Designing/strengthening injury prevention strategies is suggested especially for those who had uncontrolled seizure frequency for longer period of time. PMID: 29375913 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - January 31, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Clinical Factors Predictive for Intracranial Hemorrhage in Mild Head Injury.
In conclusion, the independent factors associated with intracranial hemorrhage in patients with mild head injury who were determined to be at moderate risk for the condition included history of hypertension, headache, loss of consciousness, and baseline GCS score. PMID: 29359046 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - January 25, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Does Cerebral Hemispheric Laterality Control Swallow Performance?
Conclusions: These results suggests that there exists differential cue lateralization hypothesis which means volume related parameters are controlled by left hemisphere and time related swallowing parameters are controlled at the right hemisphere. PMID: 29318044 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - January 12, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Leptomeningeal Contrast Enhancement Is Associated with Disability Progression and Grey Matter Atrophy in Multiple Sclerosis.
Conclusions. LMCE was shown to be an independent and significant biomarker of grey matter atrophy and disability in MS. PMID: 29291134 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - January 3, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Knowledge of Stroke Risk Factors and Warning Signs in Patients with Recurrent Stroke or Recurrent Transient Ischaemic Attack in Thailand.
Authors: Saengsuwan J, Suangpho P, Tiamkao S Abstract Stroke is a global burden. It is not known whether patients who are most at risk of stroke (recurrent stroke or recurrent transient ischaemic attack) have enough knowledge of stroke risk factors and warning signs. The aim of this study was to assess the knowledge of stroke risk factors and warning signs in this high-risk population. We performed a cross-sectional questionnaire-based study of patients with recurrent stroke or recurrent TIA admitted to Srinagarind Hospital and Khon Kaen Hospital, Thailand. A total of 140 patients were included in the study (age 65...
Source: Neurology Research International - November 14, 2017 Category: Neurology Tags: Neurol Res Int Source Type: research

Root-Securing and Brain-Fortifying Liquid Upregulates Caveolin-1 in Cell Model with Alzheimer's Disease through Inhibiting Tau Phosphorylation.
Authors: Yuan D, Zeng C, Chen Q, Wang F, Yuan L, Zhu Y, Shu Z, Chen N Abstract In order to explore the effect of root-securing and brain-fortifying Liquid- (RSBFL-) mediated caveolin-1 (CAV-1) on phosphorylation of Tau protein and to uncover underlying mechanisms of RSBFL for the prevention and treatment of Alzheimer's disease (AD), hippocampal neurons isolated from neonatal SD rats and cultured in DMEM-F12 medium were induced by exogenous Aβ1-42 to establish a cell model with AD. Meanwhile, pEGFP-C1-CAV1 and CAV1-shRNA plasmids were transfected into hippocampal neurons for CAV-1 overexpression and silence, re...
Source: Neurology Research International - November 12, 2017 Category: Neurology Tags: Neurol Res Int Source Type: research

Spinal Nerves Schwannomas: Experience on 367 Cases-Historic Overview on How Clinical, Radiological, and Surgical Practices Have Changed over a Course of 60 Years.
CONCLUSIONS: Clinical and radiological assessment of spinal schwannomas has markedly changed over the course of 50 years. Diagnostic tools have improved, and detection of recurrence has become way more sensitive. Neurophysiologic monitoring has become a useful intraoperative tool to guide resection and prevent post-op neurological impairment. PMID: 29075532 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - October 28, 2017 Category: Neurology Tags: Neurol Res Int Source Type: research

Corrigendum to "Effect of Chronic Morphine Consumption on Synaptic Plasticity of Rat's Hippocampus: A Transmission Electron Microscopy Study".
Corrigendum to "Effect of Chronic Morphine Consumption on Synaptic Plasticity of Rat's Hippocampus: A Transmission Electron Microscopy Study". Neurol Res Int. 2017;2017:4153268 Authors: Heidari MH, Amini A, Bahrami Z, Shahriari A, Movafagh A, Heidari R Abstract [This corrects the article DOI: 10.1155/2013/290414.]. PMID: 28831311 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - August 25, 2017 Category: Neurology Tags: Neurol Res Int Source Type: research

Clinicodemographic Profile of Children with Seizures in a Tertiary Care Hospital: A Cross-Sectional Observational Study.
This study was conducted to study the prevalence and clinicodemographic profile of children with seizures in a tertiary care hospital of western Nepal. This prospective cross-sectional study conducted over a period of 2 years included all admitted children (2 months-16 years) with seizures. Among 4962 admitted children, seizures were present in 3.4% (n = 168) of children, with male preponderance. 138 (82.1%) children had generalized tonic-clonic seizures (GTCS) and 30 (17.9%) children had partial seizures. GTCS were more common than partial seizures in both sexes (male = 82.7%; female = 81.2%) and age groups. There was no ...
Source: Neurology Research International - July 19, 2017 Category: Neurology Tags: Neurol Res Int Source Type: research

Comparing the Expression of Genes Related to Serotonin (5-HT) in C57BL/6J Mice and Humans Based on Data Available at the Allen Mouse Brain Atlas and Allen Human Brain Atlas.
This study used the data published by the Allen Mouse Brain Atlas (2004) for mice (C57BL/6J) and Allen Human Brain Atlas (2010) for humans (6 donors) to compare the expression of serotonin-related genes. Genes of interest were searched for manually in each case (in situ hybridization for mice and microarrays for humans), normalized expression data (z-scores) were extracted, and the results were graphed. Despite the differences in methodology, quantification, and subjects used in the process, a high degree of similarity was found between expression data. Here we compare expression in a way that allows the use of translation...
Source: Neurology Research International - June 22, 2017 Category: Neurology Tags: Neurol Res Int Source Type: research

Increased Intracranial Pressure in the Setting of Enterovirus and Other Viral Meningitides.
Authors: Beal JC Abstract Increased intracranial pressure due to viral meningitis has not been widely discussed in the literature, although associations with Varicella and rarely Enterovirus have been described. Patients with increased intracranial pressure and cerebrospinal fluid analysis suggestive of a viral process are sometimes classified as having atypical idiopathic intracranial hypertension (IIH). However, a diagnosis of IIH requires normal cerebrospinal fluid, and therefore in these cases an infection with secondary intracranial hypertension may be a more likely diagnosis. Here seven patients are presented...
Source: Neurology Research International - May 13, 2017 Category: Neurology Tags: Neurol Res Int Source Type: research

Efficacy of Keyhole Approach to Carpal Tunnel Syndrome under Ambulatory Strategy.
Conclusions. The microsurgical approach described following the keyhole principle is a treatment option that, under local anesthesia and ambulatory management, may represent an alternative strategy of an effective treatment reducing the morbidity. This trial is registered with Clinical Trials Protocol Identifier NCT03062722. PMID: 28484650 [PubMed - in process] (Source: Neurology Research International)
Source: Neurology Research International - May 11, 2017 Category: Neurology Tags: Neurol Res Int Source Type: research

Report from a Survey of Parents Regarding the Use of Cannabidiol (Medicinal cannabis) in Mexican Children with Refractory Epilepsy.
Authors: Aguirre-Velázquez CG Abstract Structured online surveys were used to explore the experiences of the parents of children with refractory epilepsy using medicinal cannabis in Mexico during September 2016. The surveys, which were completed in full, were reviewed, and 53 cases of children aged between 9 months and 18 years were identified. Of these, 43 cases (82%) were from Mexico and 10 (18%) were from Latin American countries. Of the 43 Mexican cases, the diagnoses were as follows: 20 cases (47%) had Lennox-Gastaut syndrome (LGS); 13 cases (30%) had unspecified refractory epilepsy (URE); 8 cases (19%)...
Source: Neurology Research International - April 11, 2017 Category: Neurology Tags: Neurol Res Int Source Type: research

Combined Supplementation of Choline and Docosahexaenoic Acid during Pregnancy Enhances Neurodevelopment of Fetal Hippocampus.
Authors: Thomas Rajarethnem H, Megur Ramakrishna Bhat K, Jc M, Kumar Gopalkrishnan S, Mugundhu Gopalram RB, Rai KS Abstract Choline is an essential nutrient for humans which plays an important role in structural integrity and signaling functions. Docosahexaenoic acid (DHA) is a polyunsaturated fatty acid, highly enriched in cell membranes of the brain. Dietary intake of choline or DHA alone by pregnant mothers directly affects fetal brain development and function. But no studies show the efficacy of combined supplementation of choline and DHA on fetal neurodevelopment. The aim of the present study was to analyze fe...
Source: Neurology Research International - February 18, 2017 Category: Neurology Tags: Neurol Res Int Source Type: research

Accumulation of α-Synuclein in Cerebellar Purkinje Cells of Diabetic Rats and Its Potential Relationship with Inflammation and Oxidative Stress Markers.
Accumulation of α-Synuclein in Cerebellar Purkinje Cells of Diabetic Rats and Its Potential Relationship with Inflammation and Oxidative Stress Markers. Neurol Res Int. 2017;2017:5952149 Authors: Solmaz V, Köse Özlece H, Eroglu HA, Aktuğ H, Erbaş O, Taşkıran D Abstract Objective. The present study was conducted to evaluate the relationship between plasma oxidative stress markers such as malondialdehyde (MDA) and glutathione (GSH), inflammatory marker pentraxin-3 (PTX3), and cerebellar accumulation of α-synuclein in streptozotocin- (STZ-) induced diabetes model in rats. Methods...
Source: Neurology Research International - February 1, 2017 Category: Neurology Tags: Neurol Res Int Source Type: research

Protective Effect of PPAR γ Agonists on Cerebellar Tissues Oxidative Damage in Hypothyroid Rats.
Protective Effect of PPARγ Agonists on Cerebellar Tissues Oxidative Damage in Hypothyroid Rats. Neurol Res Int. 2016;2016:1952561 Authors: Baghcheghi Y, Beheshti F, Salmani H, Soukhtanloo M, Hosseini M Abstract The aim of the current study was to investigate the effects of peroxisome proliferator-activated receptor gamma (PPARγ) agonists on cerebellar tissues oxidative damage in hypothyroid rats. The animals included seven groups: group I (control), the animals received drinking water; group II, the animals received 0.05% propylthiouracil (PTU) in drinking water; besides PTU, the animals in...
Source: Neurology Research International - January 26, 2017 Category: Neurology Tags: Neurol Res Int Source Type: research

Remotely Assessing Symptoms of Parkinson's Disease Using Videoconferencing: A Feasibility Study.
Conclusions. In using free everyday technology available in participants' homes, MDS-UPDRS ratings could be obtained without an initial home visit; however some items were unable to be scored for some participants. Use of a protocol or technological advances are likely to reduce missing items. PMID: 28116158 [PubMed - in process] (Source: Neurology Research International)
Source: Neurology Research International - January 26, 2017 Category: Neurology Tags: Neurol Res Int Source Type: research

Description of Ictal HFO Mapping in Patients with Both Temporal and Extratemporal Seizure Focus.
Authors: Ochoa JG, Rusyniak WG Abstract Objective. Review presurgical use of ictal HFO mapping to detect ictal activation areas with dual seizure focus in both the temporal and extratemporal cortex. Methods. Review of consecutive patients admitted to the University of South Alabama Epilepsy Monitoring Unit (SouthCEP) between January 2014 and October 2015, with suspected temporal lobe epilepsy and intracranial electrode recording. Ictal HFO localization was displayed in 3D reconstructed brain images using the patient's own coregistered magnetic resonance imaging (MRI) and computed tomography (CT) with the implanted ...
Source: Neurology Research International - December 27, 2016 Category: Neurology Tags: Neurol Res Int Source Type: research

Increased Serum Levels of Tumor Necrosis Factor-Alpha, Resistin, and Visfatin in the Children with Autism Spectrum Disorders: A Case-Control Study.
Authors: Ghaffari MA, Mousavinejad E, Riahi F, Mousavinejad M, Afsharmanesh MR Abstract Background. Autism spectrum disorders (ASDs) are complex disorders where the pathogenesis is not fully understood. Several proinflammatory and immunoinflammatory disturbances have been observed in the etiology of ASD. There is, however, limited knowledge on variations of adipokines in ASD. The present study aimed to analyze the serum levels of resistin, visfatin, and tumor necrosis factor-alpha (TNF-α) in children with ASD in relation to body weight, gender, and ASD severity level. Method. In total, 30 children with ASD (m...
Source: Neurology Research International - December 27, 2016 Category: Neurology Tags: Neurol Res Int Source Type: research

Cognitive Function in Parkinson's Disease Patients with and without Anxiety.
In conclusion, anxiety in PD has a measurable impact on working memory and attentional set-shifting. PMID: 27800180 [PubMed - in process] (Source: Neurology Research International)
Source: Neurology Research International - November 3, 2016 Category: Neurology Tags: Neurol Res Int Source Type: research

Assessment and Predicting Factors of Repeated Brain Computed Tomography in Traumatic Brain Injury Patients for Risk-Stratified Care Management: A 5-Year Retrospective Study.
Conclusion. Routine repeated brain CT for RSCM had no clinical benefit in mild TBI cases. PMID: 27703812 [PubMed - in process] (Source: Neurology Research International)
Source: Neurology Research International - October 7, 2016 Category: Neurology Tags: Neurol Res Int Source Type: research

The Value of ABCD2F Scoring System (ABCD2 Combined with Atrial Fibrillation) to Predict 90-Day Recurrent Brain Stroke.
Conclusion. ABCD2 and/or atrial fibrillation are not good scoring candidates for assessing the risk of recurrent stroke within first 90 days. PMID: 27642521 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - September 20, 2016 Category: Neurology Tags: Neurol Res Int Source Type: research

Electrophysiological Predictors of Clinical Outcome in Traumatic Neuropathies: A Multicenter Prospective Study.
Conclusions. Nerve conduction studies (NCS) represent the more accurate neurophysiological markers of clinical outcome in patients with TN. Significance. Serial NCS assessments predict the functional recovery in TN, increasing the accuracy of peripheral nerves surgical decision-making process. PMID: 27547450 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - August 24, 2016 Category: Neurology Tags: Neurol Res Int Source Type: research

Focusing on Increasing Velocity during Heavy Resistance Knee Flexion Exercise Boosts Hamstring Muscle Activity in Chronic Stroke Patients.
Conclusion. Chronic stroke patients are capable of performing heavy resistance training with intended high speed of contraction. Focusing on speed during the concentric phase elicited higher levels of muscle activity of the hamstrings compared to normal and blindfolded conditions, which may have implications for regaining fast muscle strength in stroke survivors. PMID: 27525118 [PubMed] (Source: Neurology Research International)
Source: Neurology Research International - August 19, 2016 Category: Neurology Tags: Neurol Res Int Source Type: research