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Specialty: Neurology
Condition: Alcoholism

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Total 356 results found since Jan 2013.

Predictors of Poor Outcome in Neuroleptic Malignant Syndrome: Retrospective Analysis of Nationwide Inpatient Sample (S32.006)
CONCLUSIONS: In patients admitted for neuroleptic malignant syndrome, every decade increment in age, acute kidney injury, seizures and respiratory failure were positive predictors of poor outcome. Every calendar year increase was a negative predictor of poor outcome. Study Supported by:Disclosure: Dr. Modi has nothing to disclose. Dr. Dharaiya has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Modi, S., Dharaiya, D. Tags: Movement Disorders: Tremor, Ataxia, and More Platform Blitz Source Type: research

CARES (Changing and Advancing Risk factor control through Educations after Stroke): A Pilot Trial of a Transitions in Care Post-discharge Telephone Intervention for Stroke Patients (S13.006)
OBJECTIVE: The purpose of study is to test the feasibility and effectiveness of a telephonic post-discharge intervention designed to improve access to care, reinforce self-management skills, improve health literacy, and screen for complications in a government-run safety net system. BACKGROUND: In the United States, risk factor control after stroke is poor, particularly among socio-economically disadvantaged populations with poor access to care. The immediate post-discharge period is a vulnerable time for stroke patients, given their risk of recurrent stroke, worsening symptoms, complications, and need for medication titra...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Hudson, L., Corrales, M., Moreno, L., Valle, N., Razmara, A., Dutta, T., Ramirez-Gomez, L., Towfighi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology and Risk Factors Source Type: research

Effects of vascular risk factors and APOE {varepsilon}4 on white matter integrity and cognitive decline
Conclusions: Vascular risk factors are associated with reduced white matter integrity among older adults, which subsequently predicted faster cognitive decline. The detrimental effects of vascular risk factors on white matter microstructure were exacerbated among APOE 4 carriers.
Source: Neurology - March 16, 2015 Category: Neurology Authors: Wang, R., Fratiglioni, L., Laukka, E. J., Lovden, M., Kalpouzos, G., Keller, L., Graff, C., Salami, A., Backman, L., Qiu, C. Tags: MRI, Cognitive aging, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Nuclear factor-¿B activation in perihematomal brain tissue correlates with outcome in patients with intracerebral hemorrhage
Background: Nuclear factor-κB (NF-κB) plays an important role in the inflammatory response after intracerebral hemorrhage (ICH). We therefore proposed that NF-κB activation in perihematomal brain tissue might correlate with clinical outcome in patients with ICH. To confirm this, we studied clinical data of 45 patients with ICH and NF-κB activation in perihematomal brain tissue and analyzed predictors of clinical outcome as well as the predictive value of NF-κB activation. Methods: Forty-five patients with spontaneous basal ganglia hemorrhage were prospectively investigated. The clinical data were collected, which incl...
Source: Journal of Neuroinflammation - March 15, 2015 Category: Neurology Authors: Ze-Li ZhangYu-Guang LiuQi-Bing HuangHong-Wei WangYan SongZhen-Kuan XuFeng Li Source Type: research

Nuclear factor-κB activation in perihematomal brain tissue correlates with outcome in patients with intracerebral hemorrhage
Background: Nuclear factor-κB (NF-κB) plays an important role in the inflammatory response after intracerebral hemorrhage (ICH). We therefore proposed that NF-κB activation in perihematomal brain tissue might correlate with clinical outcome in patients with ICH. To confirm this, we studied clinical data of 45 patients with ICH and NF-κB activation in perihematomal brain tissue and analyzed predictors of clinical outcome as well as the predictive value of NF-κB activation. Methods: Forty-five patients with spontaneous basal ganglia hemorrhage were prospectively investigated. The clinical data were collected, which incl...
Source: Journal of Neuroinflammation - March 15, 2015 Category: Neurology Authors: Ze-Li ZhangYu-Guang LiuQi-Bing HuangHong-Wei WangYan SongZhen-Kuan XuFeng Li Source Type: research

Long-term disability after lacunar stroke: Secondary prevention of small subcortical strokes
Conclusions: In lacunar stroke patients, older age was associated with worsening long-term disability, even without recurrence. Worse long-term function was associated with diabetes, cognitive status, and prior stroke, and regional differences may be attributable to variations in health care delivery or scale interpretation.
Source: Neurology - March 9, 2015 Category: Neurology Authors: Dhamoon, M. S., McClure, L. A., White, C. L., Lakshminarayan, K., Benavente, O. R., Elkind, M. S. V., On behalf of the SPS3 Investigators Tags: All Cerebrovascular disease/Stroke, All Rehabilitation, All epidemiology ARTICLE Source Type: research

Predictor's of Mortality in Patients with Aneurysmal Subarachnoid Haemorrhage and Reebleding.
Conclusions. The black/mixed race, SBP, and serum glucose were independent predictors of mortality. Three or more complications were associated with increasing the probability to death. Further investigation is necessary to validate these findings. PMID: 25722889 [PubMed]
Source: Neurology Research International - March 2, 2015 Category: Neurology Tags: Neurol Res Int Source Type: research

Cannabis and Stroke: Systematic Appraisal of Case Reports Brief Reports
Conclusions— Many case reports support a causal link between cannabis and cerebrovascular events. This accords well with epidemiological and mechanistic research on the cerebrovascular effects of cannabis.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Hackam, D. G. Tags: Secondary prevention, Cerebrovascular disease/stroke, Risk Factors for Stroke, Epidemiology Brief Reports Source Type: research

Alcohol Consumption at Midlife and Risk of Stroke During 43 Years of Follow-Up: Cohort and Twin Analyses Clinical Sciences
Conclusions— Stroke-risk associated with heavy drinking (>2 drinks/d) in midlife seems to predominate over well-known risk factors, hypertension and diabetes, until the age of 75 years and may shorten time to stroke by 5 years above and beyond covariates and genetic/early-life factors. Alcohol consumption should be considered an age-varying risk factor for stroke.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Kadlecova, P., Andel, R., Mikulik, R., Handing, E. P., Pedersen, N. L. Tags: Cerebrovascular disease/stroke, Risk Factors Clinical Sciences Source Type: research

Pattern and risk factors of stroke in the young among stroke patients admitted in medical college hospital, Thiruvananthapuram
Conclusion: In all, 15% of total stroke occurred in young adults <50 years. The proportion of hemorrhagic stroke in young adults is higher than in elderly. Atrial fibrillation is identified as an independent risk factor of stroke in the young. Compared with stroke in elderly alcohol use, smoking, hyperlipidemia, and cardiac diseases, which are known risk factors, are higher in young stroke.
Source: Annals of Indian Academy of Neurology - February 10, 2015 Category: Neurology Authors: Praveen Prasannakumar SubhaSabarinadh Muraleedharan Pillai GeethakumariMohan AthiraZinia Thajudeen Nujum Source Type: research

Lower hazard ratio for death in women with cerebral hemorrhage
ConclusionWe evaluated HR for death comparing men to women in stroke and in each stroke subtype. Women with CH had lower HR for death within 30 days after stroke than men.
Source: Acta Neurologica Scandinavica - February 3, 2015 Category: Neurology Authors: K. Shigematsu, Y. Watanabe, H. Nakano, Tags: Original Article Source Type: research

More evidence against alcohol or smoking in patients with unruptured intracranial aneurysm
Intracranial aneurysms are common, with a prevalence of 3% in the general population.1 The growing availability of brain imaging has increased the number of incidentally discovered aneurysms. Rupture of intracranial aneurysms and the resulting subarachnoid hemorrhage (SAH) has a high case fatality and morbidity, and occurs at a relatively young age compared with other types of stroke.2 As yet, we do not have a medical treatment to prevent intracranial aneurysm formation and its subsequent rupture. Our only preventive treatments for existing aneurysms consist of invasive surgery or endovascular treatment, each with inherent...
Source: Neurology - February 2, 2015 Category: Neurology Authors: Pera, J., Ruigrok, Y. M. Tags: All Clinical Neurology, Prognosis, Cohort studies, Neonatal seizures, Subarachnoid hemorrhage EDITORIALS Source Type: research

Alcohol Boosts Stroke Risk More Than Do Hypertension, DiabetesAlcohol Boosts Stroke Risk More Than Do Hypertension, Diabetes
Consuming more than two alcoholic drinks a day was a stronger predictor of stroke in early old age than were the traditional risk factors of hypertension or diabetes. Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - January 30, 2015 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Increasing stroke incidence and prevalence of risk factors in a low-income Chinese population
Conclusions: The incidence of stroke in rural China increased rapidly, particularly among middle-aged adults, along with a concurrent increase in risk factor prevalence. These findings suggest that without controlling these risk factors, stroke incidence will continue to increase over future decades in China.
Source: Neurology - January 26, 2015 Category: Neurology Authors: Wang, J., An, Z., Li, B., Yang, L., Tu, J., Gu, H., Zhan, C., Liu, B., Su, T.-C., Ning, X. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Incidence studies, Risk factors in epidemiology ARTICLE Source Type: research

Rates and risk factors for progression to incident dementia vary by age in a population cohort
Conclusion: Risk and protective factors were only found for incident dementia with onset before the median onset age of 87 years, and not for those with later onset. Either unexplored risk factors explain the continued increase in incidence with age, or unknown protective factors are allowing some individuals to delay onset into very old age.
Source: Neurology - December 29, 2014 Category: Neurology Authors: Ganguli, M., Lee, C.-W., Snitz, B. E., Hughes, T. F., McDade, E., Chang, C.-C. H. Tags: All Cognitive Disorders/Dementia, MCI (mild cognitive impairment), Cohort studies ARTICLE Source Type: research