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Specialty: Neurology
Condition: Alcoholism

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Total 356 results found since Jan 2013.

Alcohol use and hospital readmissions following stroke: A safety net hospital experience
The purpose of this study is to identify predictors of stroke-related readmissions at 30days on a safety net hospital level and suggest interventions to reduce the number of readmissions.
Source: Journal of the Neurological Sciences - December 14, 2017 Category: Neurology Authors: Simy Parikh, Paul George, Kevin Wilson, Denis Rybin, Anna DePold Hohler Source Type: research

Influence of Prior Nicotine and Alcohol Use on Functional Outcome in Patients after Intracerebral Hemorrhage
The influence of prior nicotine or alcohol use (legal drug use [LDU]) on outcome measures after intracerebral hemorrhage (ICH) is insufficiently established. We investigated drug-specific associations with (1) neuroradiologic and clinical parameters and (2) functional long-term outcome after ICH.
Source: Journal of Stroke and Cerebrovascular Diseases - November 27, 2017 Category: Neurology Authors: Jochen A. Sembill, Maximilian I. Spr ügel, Stefan T. Gerner, Vanessa D. Beuscher, Antje Giede-Jeppe, Margarete Stocker, Philip Hoelter, Hannes Lücking, Joji B. Kuramatsu, Hagen B. Huttner Source Type: research

Unruptured Brain Arteriovenous Malformations Brief Report
Background and Purpose—In light of evidence from ARUBA (A Randomized Trial of Unruptured Brain Arteriovenous Malformations), neurovascular specialists had to reconsider deliberate treatment of unruptured brain arteriovenous malformations (uBAVMs). Our objective was to determine the outcomes of uBAVM treated with primary embolization using ethylene vinyl alcohol (ONYX).Methods—Patients with uBAVM who met the inclusion criteria of ARUBA and were treated with primary Onyx embolization were assigned to this retrospective study. The primary outcome was the modified Rankin Scale score. Secondary outcomes were stroke or death...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Uri Singfer, Dimitri Hemelsoet, Peter Vanlangenhove, Frederic Martens, Luc Verbeke, Dirk Van Roost, Luc Defreyne Tags: Treatment, Cerebrovascular Disease/Stroke, Cerebrovascular Malformations, Cerebrovascular Procedures Brief Reports Source Type: research

Serum 1,5-Anhydroglucitol: Risk Factor of Acute Ischemic Stroke and Transient Ischemic Attack in Well-Controlled Diabetes
Conclusions: Low serum 1,5-AG levels could be a possible marker for AIS/TIA risk in patients with well-controlled DM.Cerebrovasc Dis 2017;44:325 –329
Source: Cerebrovascular Diseases - October 26, 2017 Category: Neurology Source Type: research

Risk factors, vascular lesion distribution, outcome and recurrence of strokes due to intracranial atherosclerosis: One year data from Hyderabad stroke registry
Conclusion: Risk factors, distribution of vascular lesions and high recurrence of stroke due to ICAS in this study is similar to that reported from other Asian countries. Aggressive medical management and risk factor control remains the best strategy for preventing recurrence.
Source: Annals of Indian Academy of Neurology - October 25, 2017 Category: Neurology Authors: Raghu Ram Subhash Kaul Suvarna Alladi Jabeen S Afshan T Surya Prabha Abhijeet Kohat Swetha Tandra Jyotsna Y Rani Source Type: research

Predicting Major Bleeding in Ischemic Stroke Patients With Atrial Fibrillation Brief Report
Conclusions—Performance of prediction models for major bleeding in patients with cerebral ischemia and atrial fibrillation is modest but comparable with performance in patients with only atrial fibrillation. Bleeding risk scores cannot guide treatment decisions for oral anticoagulants but may still be useful to identify modifiable risk factors for bleeding. Clinical usefulness may be best for ORBIT, which is based on a limited number of easily obtainable variables and showed reasonable performance.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Nina A. Hilkens, Ale Algra, Jacoba P. Greving Tags: Atrial Fibrillation, Secondary Prevention, Ischemic Stroke Brief Reports Source Type: research

Smoking cessation and secondary stroke prevention
The 7 million adult stroke survivors in the United States remain at high risk for a recurrent stroke. The increased morbidity and cost associated with recurrent stroke, in addition to the 5% to 20% yearly stroke recurrence, support the need for additional investigations into secondary stroke prevention.1,2 Stroke prevention guidelines, whether primary or secondary, focus on risk factor control of modifiable risk factors. The American Heart Association/American Stroke Association guidelines for secondary stroke prevention indicate evidence-based risk factor control, interventional approaches, and treatment options as approa...
Source: Neurology - October 16, 2017 Category: Neurology Authors: Boehme, A. Tags: EDITORIALS Source Type: research

Clinical Reasoning: A 61-year-old man with conjugate gaze deviation, hemiparesis, and asymmetric reflexes
A 61-year-old man with a history of alcoholic cirrhosis was transferred from an outside hospital for spontaneous bacterial peritonitis, septic shock, and respiratory failure after intubation. The patient was initially on sedation; however, more than 48 hours after the sedative was discontinued, his mental status remained depressed and he also developed new onset of conjugate rightward gaze deviation. On neurologic examination, the patient was unresponsive to verbal stimuli and sternal rub. He could not follow any command, including closing or opening eyes and squeezing hands. He had remarkable conjugate, forced eye deviati...
Source: Neurology - August 28, 2017 Category: Neurology Authors: Lin, C.-Y., Yoo, J. Y., Doshi, A., Colman, R. Tags: MRI, Clinical neurology examination, All Cerebrovascular disease/Stroke, Critical care, Video/ EEG use in epilepsy RESIDENT AND FELLOW SECTION Source Type: research

Mystery Case: A case of fulminant encephalopathy in a 69-year-old woman
A 69-year-old right-handed woman was admitted to the medical intensive care unit for acute encephalopathy. Her medical history included sickle cell disease (hemoglobin sickle cell [HbSC]) with bone involvement (bilateral femoral head osteonecrosis) and rare sickle cell crises with joint pain and hemolytic anemia requiring red blood cell transfusions, sarcoidosis, diabetes, hypertension, and hypothyroidism. She never smoked cigarettes and never used recreational drugs or alcohol, and there was no history of recent travel. The patient's daughter reported that the patient was found unresponsive lying on the floor in the morni...
Source: Neurology - August 28, 2017 Category: Neurology Authors: Lamotte, G., Williams, C. Tags: MRI, Other cerebrovascular disease/ Stroke, Coma, Critical care, Embolism RESIDENT AND FELLOW SECTION Source Type: research

Serum matrix metalloproteinase-9 levels and prognosis of acute ischemic stroke
Conclusions: Higher serum MMP-9 levels in the acute phase of ischemic stroke were associated with increased risk of mortality and major disability, suggesting that serum MMP-9 could be an important prognostic factor for ischemic stroke.
Source: Neurology - August 21, 2017 Category: Neurology Authors: Zhong, C., Yang, J., Xu, T., Xu, T., Peng, Y., Wang, A., Wang, J., Peng, H., Li, Q., Ju, Z., Geng, D., Zhang, Y., He, J., For the CATIS Investigators Tags: Stroke prevention, Prognosis, All Cerebrovascular disease/Stroke, Clinical trials Observational study (Cohort, Case control), Cohort studies ARTICLE Source Type: research

A Pilot Trial of a Lifestyle Intervention for Stroke Survivors: Design of Healthy Eating and Lifestyle after Stroke (HEALS)
Stroke survivors have high rates of subsequent cardiovascular and recurrent cerebrovascular events, and mortality. While healthy lifestyle practices - including a diet rich in fruits and vegetables, limited alcohol intake, and regular physical activity - can mitigate these outcomes, few stroke survivors adhere to them. Minorities from socioeconomically disadvantaged communities who obtain care in safety-net health systems experience the most barriers to implementing healthy lifestyle changes after stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 16, 2017 Category: Neurology Authors: Valerie A. Hill, Barbara G. Vickrey, Eric M. Cheng, Natalie P. Valle, Monica Ayala-Rivera, Lilian Moreno, Cynthia Munoz, Heidi Dombish, Annaliese Espinosa, Debbie Wang, Dina Ochoa, Allison Chu, Rebecca Heymann, Amytis Towfighi Source Type: research

Relationship between factor V leiden gene variant and risk of ischemic stroke: A case & #8211;control study
Conclusion: The present study suggests that Factor V Leiden G1691A polymorphism may be significantly associated with the risk of large vessel subtype of IS. Large sample size studies using prospective cohort designs are required to corroborate the present findings.
Source: Annals of Indian Academy of Neurology - August 10, 2017 Category: Neurology Authors: Amit Kumar Shubham Misra Ram Sagar Pradeep Kumar Arun K Yadav Pumanshi Talwar Ritesh Raj Kameshwar Prasad Source Type: research

Modifiable Risk Factors for Stroke and Strategies for Stroke Prevention
Semin Neurol 2017; 37: 237-258 DOI: 10.1055/s-0037-1603685The pathophysiology of stroke is well characterized, and 9 out of 10 strokes are due to modifiable factors. However, preventive strategies thus far have been relatively ineffective in curbing the global stroke burden, which is projected to increase given the aging of the world's population and epidemiological transition in many low- to middle-income countries. In this review we will summarize our current understanding of behavioral, environmental, and metabolic stroke risk factors not covered elsewhere in this issue. Specifically, we will review the evidence for env...
Source: Seminars in Neurology - July 31, 2017 Category: Neurology Authors: Hill, Valerie A. Towfighi, Amytis Tags: Review Article Source Type: research

Alcohol Consumption and Aneurysmal Subarachnoid Hemorrhage
AbstractAlcohol consumption may be a modifiable risk factor for rupture of intracranial aneurysms. Our aim is to evaluate the association between ruptured aneurysms and alcohol consumption, intensity, and cessation. The medical records of 4701 patients with 6411 radiographically confirmed intracranial aneurysms diagnosed at the Brigham and Women ’s Hospital and Massachusetts General Hospital between 1990 and 2016 were reviewed. Individuals were divided into cases with ruptured aneurysms and controls with unruptured aneurysms. Univariable and multivariable logistic regression analyses were performed to determine the assoc...
Source: Translational Stroke Research - July 27, 2017 Category: Neurology Source Type: research

Effects of increasing IV tPA-treated stroke mimic rates at CT-based centers on clinical outcomes
Conclusions: Thrombolysis of stroke mimics is increasing at our CT-based spoke hospitals and not at our MRI-based hub hospitals. Caution should be used in interpreting clinical outcomes based on large stroke databases when stroke diagnosis at discharge is unclear. Inadvertent reporting of treated stroke mimics as strokes will artificially elevate overall favorable clinical outcomes with additional downstream costs to patients and the health care system.
Source: Neurology - July 24, 2017 Category: Neurology Authors: Burton, T. M., Luby, M., Nadareishvili, Z., Benson, R. T., Lynch, J. K., Latour, L. L., Hsia, A. W. Tags: Outcome research, CT, MRI, DWI, All Cerebrovascular disease/Stroke ARTICLE Source Type: research