Targeting Reperfusion Injury in the Age of Mechanical Thrombectomy [Basic Science Advances for Clinicians]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Atsushi Mizuma, Je Sung You, Midori A. Yenari Tags: Animal Models of Human Disease, Basic Science Research, Inflammation, Oxidant Stress Basic Science Advances for Clinicians Source Type: research

Role of Brain and Vessel Imaging for the Evaluation of Transient Ischemic Attack and Minor Stroke [Topical Review]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: A.Y.X. Yu, S.B. Coutts Tags: Ischemic Stroke, Transient Ischemic Attack (TIA) Topical Reviews Source Type: research

Blood Pressure in Acute Stroke [Topical Review]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Philip M. Bath, Jason P. Appleton, Kailash Krishnan, Nikola Sprigg Tags: High Blood Pressure, Intracranial Hemorrhage, Ischemic Stroke Topical Reviews Source Type: research

Trials and Frontiers in Carotid Endarterectomy and Stenting [Topical Review]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Douglas W. Jones, Thomas G. Brott, Marc L. Schermerhorn Tags: Revascularization, Stent, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Stenosis Topical Reviews Source Type: research

William M. Feinberg Award for Excellence in Clinical Stroke [Special Reports]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Joanna M. Wardlaw Tags: Blood-Brain Barrier, Cerebrovascular Disease/Stroke, Ischemic Stroke Special Report Source Type: research

Stroke 112 [Brief Report]
Conclusions—Stroke 112, a universal stroke educational program without language barriers was developed. It could potentially be implemented worldwide, especially where 112 is used as an emergency phone number. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Jing Zhao, Maryellen F. Eckenhoff, Wei-Zen Sun, Renyu Liu Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Continuation or Discontinuation of Anticoagulation in the Early Phase After Acute Ischemic Stroke [Brief Report]
Background and Purpose—There is no consensus on whether anticoagulation should be continued or temporarily stopped in patients suffering acute ischemic stroke while using anticoagulation. We assessed treatment variations and outcomes in these patients.Methods—Post hoc analysis of PASS (Preventive Antibiotics in Stroke Study). We included patients with acute ischemic stroke who used anticoagulation at admission. We compared clinical outcomes, thrombotic, and major bleeding events at 3 months.Results—Nine percent (192/2101) of the patients with acute ischemic stroke used anticoagulation at admission (186 vi...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Adrien E. Groot, Jan-Dirk M. Vermeij, Willeke F. Westendorp, Paul J. Nederkoorn, Diederik van de Beek, Jonathan M. Coutinho Tags: Secondary Prevention, Anticoagulants, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Nonconvulsive Status Epilepticus in Acute Intracerebral Hemorrhage [Brief Report]
Conclusions—NCSE is not a rare complication of acute ICH. Craniotomy and lobar involvement are independently associated with NCSE in patients with acute ICH. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Soichiro Matsubara, Shoichiro Sato, Tomohiro Kodama, Satoshi Egawa, Hidetoshi Nakamoto, Kazunori Toyoda, Yuichi Kubota Tags: Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Brief Reports Source Type: research

Neurologic Outcome Predictors in Pediatric Intracerebral Hemorrhage [Brief Report]
Background and Purpose—Intracerebral hemorrhage is a considerable source of morbidity and mortality. This 3-center study describes outcomes of pediatric intracerebral hemorrhage and identifies 2-year neurological outcome predictors.Methods—Children 29 days to 18 years of age presenting with intracerebral hemorrhage from March 2007 to May 2015 were enrolled prospectively. Exclusion criteria included trauma; intracranial tumor; hemorrhagic transformation of arterial ischemic stroke or cerebral sinovenous thrombosis; isolated subdural, epidural, or subarachnoid hemorrhage; and abnormal baseline neurological functi...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Giulia S. Porcari, Lauren A. Beslow, Rebecca N. Ichord, Daniel J. Licht, Jonathan T. Kleinman, Lori C. Jordan Tags: Pediatrics, Prognosis, Mortality/Survival, Intracranial Hemorrhage Brief Reports Source Type: research

Antiplatelet Therapy, Cerebral Microbleeds, and Intracerebral Hemorrhage [Brief Report]
Conclusions—Antiplatelet drug use was associated with increased risk of strictly lobar MBs and increased the intracerebral hemorrhage incidence in participants with CMBs. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Jianting Qiu, Huirong Ye, Jialiang Wang, Jiangzhi Yan, Jian Wang, Yujie Wang Tags: Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Brief Reports Source Type: research

Low Serum Calcium and Magnesium Levels and Rupture of Intracranial Aneurysms [Brief Report]
Conclusions—In this large case–control study, hypocalcemia and hypomagnesemia at diagnosis were significantly associated with ruptured aneurysms. Impaired hemostasis caused by hypocalcemia and hypomagnesemia may explain this association. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Anil Can, Robert F. Rudy, Victor M. Castro, Dmitriy Dligach, Sean Finan, Sheng Yu, Vivian Gainer, Nancy A. Shadick, Guergana Savova, Shawn Murphy, Tianxi Cai, Scott T. Weiss, Rose Du Tags: Risk Factors, Cerebral Aneurysm Brief Reports Source Type: research

Early Cerebral Vein After Endovascular Ischemic Stroke Treatment Predicts Symptomatic Reperfusion Hemorrhage [Brief Report]
Conclusions—ECV on postendovascular mechanical thrombectomy digital subtraction angiography is highly diagnostic of subsequent symptomatic reperfusion hemorrhage in this data set. This finding has important implications for post-treatment management of blood pressure and anticoagulation. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Samuel C.D. Cartmell, Robyn L. Ball, Rajani Kaimal, Nicholas A. Telischak, Michael P. Marks, Huy M. Do, Robert L. Dodd, Gregory W. Albers, Maarten G. Lansberg, Jeremy J. Heit Tags: Cerebrovascular Procedures, Intracranial Hemorrhage, Ischemic Stroke Brief Reports Source Type: research

Elevated Plasma D-Dimer Level Is Associated With Short-Term Risk of Ischemic Stroke in Patients With Acute Heart Failure [Brief Report]
We examined 721 consecutive hospitalized AHF patients with plasma D-dimer level on admission from our prospective registry between January 2013 and May 2016. The study end points were incidence of ischemic stroke during hospitalization and at 30 days after admission.Results—Of the total participants (mean age, 76 years; male, 60%; atrial fibrillation, 54%; mean left ventricular ejection fraction, 38%), in-hospital ischemic stroke occurred in 18 patients (2.5%) during a median hospitalization period of 21 days, and 30-day ischemic stroke occurred in 16 patients (2.2%). Higher D-dimer level on admission was an independ...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Yasuhiro Hamatani, Toshiyuki Nagai, Michikazu Nakai, Kunihiro Nishimura, Yasuyuki Honda, Hiroki Nakano, Satoshi Honda, Naotsugu Iwakami, Yasuo Sugano, Yasuhide Asaumi, Takeshi Aiba, Teruo Noguchi, Kengo Kusano, Kazunori Toyoda, Satoshi Yasuda, Hiroyuki Yo Tags: Heart Failure, Ischemic Stroke Brief Reports Source Type: research

Cardiovascular and Cerebrovascular Mortality Associated With Acute Exposure to PM2.5 in Mexico City [Brief Report]
Background and Purpose—Acute exposure to particulate matter with aerodynamic diameter (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Ivan Gutierrez–Avila, Leonora Roȷas–Bracho, Horacio Rioȷas–Rodriguez, Itai Kloog, Allan C. Just, Stephen J. Rothenberg Tags: Cardiovascular Disease, Epidemiology, Heart Failure, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Protective Effects of Brain Infarction by N-Acetylcysteine Derivatives [Basic Sciences]
Conclusions—The results indicate that detoxification of acrolein by NAC derivatives is caused through glutathione conjugation with acrolein catalyzed by glutathione S-transferases, which can be stabilized by NAC derivatives. This is a new concept of acrolein detoxification by NAC derivatives. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Takeshi Uemura, Kenta Watanabe, Kenta Ko, Kyohei Higashi, Noriyuki Kogure, Mariko Kitajima, Hiromitsu Takayama, Koichi Takao, Yoshiaki Sugita, Akihiko Sakamoto, Yusuke Terui, Toshihiko Toida, Keiko Kashiwagi, Kazuei Igarashi Tags: Animal Models of Human Disease, Ischemia, Oxidant Stress, Ischemic Stroke Original Contributions Source Type: research

Diverse Inflammatory Response After Cerebral Microbleeds Includes Coordinated Microglial Migration and Proliferation [Basic Sciences]
Conclusions—Although microhemorrhages are small in size, the brain responds to a single bleed with an inflammatory response that involves brain-resident and blood-derived cells, persists for weeks, and may impact the adjacent brain microenvironment. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Sung Ji Ahn, Josef Anrather, Nozomi Nishimura, Chris B. Schaffer Tags: Animal Models of Human Disease, Inflammation, Imaging, Intracranial Hemorrhage Original Contributions Source Type: research

Taurine Reduces tPA (Tissue-Type Plasminogen Activator)-Induced Hemorrhage and Microvascular Thrombosis After Embolic Stroke in Rat [Basic Sciences]
Conclusions—Our results suggest that taurine in combination with tPA may be a clinically feasible approach toward future attempts at combination stroke therapy. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Rong Jin, Adam Y. Xiao, Shan Liu, Min Wang, Guohong Li Tags: Animal Models of Human Disease, Ischemic Stroke Original Contributions Source Type: research

Inhibition of miR-141-3p Ameliorates the Negative Effects of Poststroke Social Isolation in Aged Mice [Basic Sciences]
Conclusions—miR-141-3p is increased with poststroke isolation. Inhibition of miR-141-3p improved mortality, neurological deficits, and decreased infarct volumes. Importantly, these therapeutic effects occurred in aged animals, the population most at risk for stroke and poststroke isolation. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Rajkumar Verma, Rodney M. Ritzel, Nia M. Harris, Juneyoung Lee, TaeHee Kim, Gopal Pandi, Raghu Vemuganti, Louise D. McCullough Tags: Basic Science Research, Ischemia, Translational Studies Original Contributions Source Type: research

Impact of Transcranial Doppler Ultrasound on Logistics and Outcomes in Stroke Thrombolysis [Clinical Sciences]
Background and Purpose—Diagnostic transcranial Doppler ultrasound (TCD) is commonly used in patients with acute stroke before or during treatment with intravenous thrombolysis (IVT). We aimed to assess how much TCD delays IVT initiation and whether TCD influences outcomes.Methods—We analyzed data from the SITS-ISTR (Safe Implementation of Thrombolysis in Stroke–International Stroke Thrombolysis Register) collected from December 2002 to December 2011. Outcomes were door-to-needle time, symptomatic intracerebral hemorrhage, functional outcome per the modified Rankin Scale, and mortality at 3 months.Results&...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Michael V. Mazya, Niaz Ahmed, Elsa Azevedo, Antoni Davalos, Laura Dorado, Michal Karlinski, Svetlana Lorenzano, Jiři Neumann, Danilo Toni, Tiago P. Moreira Tags: Ultrasound, Health Services, Ischemic Stroke Original Contributions Source Type: research

Efficacy of Endovascular Therapy in Acute Ischemic Stroke Depends on Age and Clinical Severity [Clinical Sciences]
Background and Purpose—Efficacy of endovascular treatment (EVT) for ischemic stroke because of large vessel occlusion may depend on patients’ age and stroke severity; we, therefore, developed a prognosis score based on these variables and examined whether EVT efficacy differs between patients with good, intermediate, or poor prognostic score.Methods—A total of 4079 patients with an acute ischemic stroke were identified from the Paris Stroke Consortium registry. We developed the stroke checkerboard (SC) score (SC score=1 point per decade ≥50 years of age and 2 points per 5 points on the National Institu...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Raphael Le Bouc, Frederic Clarencon, Elena Meseguer, Bertrand Lapergue, Arturo Consoli, Guillaume Turc, Olivier Naggara, Duc Long Duong, Jerome Servan, Peggy Reiner, Marc Antoine Labeyrie, Mathieu Fisselier, Raphael Blanc, Wassim Farhat, Christine Pires, Tags: Revascularization, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Efficacy and Safety of Ticagrelor in Relation to Aspirin Use Within the Week Before Randomization in the SOCRATES Trial [Clinical Sciences]
Conclusions—In this secondary analysis from SOCRATES, fewer primary end points occurred on ticagrelor treatment than on aspirin in patients receiving aspirin before randomization, but there was no significant treatment-by-prior-aspirin interaction. A new study will investigate the benefit-risk of combining ticagrelor and aspirin in patients with acute cerebral ischemia (URL: https://www.clinicaltrials.gov. Unique identifier: NCT03354429).Clinical Trial Registration—URL: https://www.clinicaltrials.gov. Unique identifier: NCT01994720. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: K.S. Lawrence Wong, Pierre Amarenco, Gregory W. Albers, Hans Denison, J. Donald Easton, Scott R. Evans, Peter Held, Anders Himmelmann, Scott E. Kasner, Mikael Knutsson, Per Ladenvall, Kazuo Minematsu, Carlos A. Molina, Yongjun Wang, S. Claiborne Johnston Tags: Ischemic Stroke Original Contributions Source Type: research

Similar Outcomes for Contact Aspiration and Stent Retriever Use According to the Admission Clot Burden Score in ASTER [Clinical Sciences]
Conclusions—First-line mechanical thrombectomy with contact aspiration compared with stent retriever did not result in an increased successful reperfusion rate in acute ischemic stroke patients with large vessel occlusion of the anterior circulation according to the admission CBS. The latter, however, seems to be a reliable prognostic indicator of angiographic and clinical outcome. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Francois Zhu, Bertrand Lapergue, Maeva Kyheng, Raphael Blanc, Julien Labreuche, Malek Ben Machaa, Alain Duhamel, Gautier Marnat, Suzana Saleme, Vincent Costalat, Serge Bracard, Sebastien Richard, Hubert Desal, Mikael Mazighi, Arturo Consoli, Michel Piotin Tags: Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Beyond Large Vessel Occlusion Strokes [Clinical Sciences]
Conclusions—Distal intracranial occlusions can be treated safely and successfully with endovascular therapy. These results need to be corroborated by larger prospective controlled studies. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Jonathan A. Grossberg, Leticia C. Rebello, Diogo C. Haussen, Mehdi Bouslama, Meredith Bowen, Clara M. Barreira, Samir R. Belagaje, Michael R. Frankel, Raul G. Nogueira Tags: Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Texture Analysis of T1-Weighted and Fluid-Attenuated Inversion Recovery Images Detects Abnormalities That Correlate With Cognitive Decline in Small Vessel Disease [Clinical Sciences]
Conclusions—TP, which can be obtained from routine clinical images, are abnormal in SVD, and the degree of abnormality correlates with executive dysfunction and global cognition at baseline and decline during 5 years. TP may be useful to assess disease severity in clinically collected data. This needs testing in data clinically acquired across multiple sites. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Daniel J. Tozer, Eva Zeestraten, Andrew J. Lawrence, Thomas R. Barrick, Hugh S. Markus Tags: Imaging, Magnetic Resonance Imaging (MRI), Vascular Disease Original Contributions Source Type: research

Quantifying Infarct Growth and Secondary Injury Volumes [Clinical Sciences]
Conclusions—The contributions of IG and AD to lesion expansion can be measured separately over time through the use of image registration. This approach can be used to combine imaging outcome data from computed tomography and MRI. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: George W.J. Harston, Davide Carone, Fintan Sheerin, Mark Jenkinson, James Kennedy Tags: Imaging, Ischemic Stroke Original Contributions Source Type: research

Long-Term Prognosis of Patients With Transient Ischemic Attack or Stroke and Symptomatic Vascular Disease in Multiple Arterial Beds [Clinical Sciences]
Background and Purpose—Cerebrovascular, coronary, and peripheral vascular disease have common underlying arterial pathology and risk factors, but the clinical significance of multiple-territory disease in patients with transient ischemic attack (TIA)/ischemic stroke is unclear, particularly whether the number of clinically affected territories still predicts long-term outcome on current standard secondary prevention therapies.Methods—In a population-based study of 92 728 individuals in Oxfordshire, United Kingdom (Oxford Vascular Study), we studied patients presenting with TIA/ischemic stroke (2002&ndash...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Mirjam R. Heldner, Linxin Li, Nicola G. Lovett, Magdalena M. Kubiak, Shane Lyons, Peter M. Rothwell Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Transient Ischemic Attack (TIA), Vascular Disease Original Contributions Source Type: research

Baroreflex Impairment After Subarachnoid Hemorrhage Is Associated With Unfavorable Outcome [Clinical Sciences]
Conclusions—In SAH, early BRS was associated with 3-month outcome. This conclusion requires confirmation on a larger number of patients in a multicentre study. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Nathalie Nasr, Rita Gaio, Marek Czosnyka, Karol Budohoski, Xiuyun Liu, Joseph Donnelly, Marek Sykora, Peter Kirkpatrick, Anne Pavy-Le Traon, Christina Haubrich, Vincent Larrue, Peter Smielewski Tags: Autonomic Nervous System, Pathophysiology, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

High Serum Level of Matrix Metalloproteinase-7 Is Associated With Increased Risk of Spontaneous Subarachnoid Hemorrhage [Clinical Sciences]
Conclusions—High serum level of MMP-7 was associated with increased risk of incident spontaneous SAH, independently of the main risk factors for SAH. High serum levels of MMP-2 and MMP-9 did not predict SAH risk. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Martin Soderholm, Gunilla Nordin Fredrikson, Jan Nilsson, Gunnar Engstrom Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Original Contributions Source Type: research

17p12 Influences Hematoma Volume and Outcome in Spontaneous Intracerebral Hemorrhage [Clinical Sciences]
Background and Purpose—Hematoma volume is an important determinant of clinical outcome in spontaneous intracerebral hemorrhage (ICH). We performed a genome-wide association study (GWAS) of hematoma volume with the aim of identifying novel biological pathways involved in the pathophysiology of primary brain injury in ICH.Methods—We conducted a 2-stage (discovery and replication) case-only genome-wide association study in patients with ICH of European ancestry. We utilized the admission head computed tomography to calculate hematoma volume via semiautomated computer-assisted technique. After quality control and i...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Sandro Marini, William J. Devan, Farid Radmanesh, Laura Miyares, Timothy Poterba, Bȷorn M. Hansen, Bo Norrving, Jordi Jimenez–Conde, Eva Giralt–Steinhauer, Roberto Elosua, Elisa Cuadrado–Godia, Carolina Soriano, Jaume Roquer, Chri Tags: Genetics, Computerized Tomography (CT), Quality and Outcomes, Intracranial Hemorrhage Original Contributions Source Type: research

Effects of Blood Pressure in the Early Phase of Ischemic Stroke and Stroke Subtype on Poststroke Cognitive Impairment [Clinical Sciences]
This study was to investigate the impact of BP levels in the early phase of ischemic stroke and stroke subtype on PSCI.Methods—Seven hundred and ninety-six patients with acute ischemic stroke were included. Cognitive function was assessed after stroke onset using the Montreal Cognitive Assessment. Patients were divided into quintiles according to systolic BP and diastolic BP levels in the early phase. Subtype analyses were according to Trial of ORG 10172 in Acute Stroke Treatment classification (infarct cause) and Oxfordshire Community Stroke Project classification (infarct location).Results—After adjusting for...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Mingli He, Jin’e Wang, Na Liu, Xiao Xiao, Shan Geng, Pin Meng, Niu Ji, Yong’an Sun, Bingchao Xu, Yingda Xu, Xinyu Zhou, Guanghui Zhang, Xiaobing He, Zenglin Cai, Zaipo Li, Bei Wang, Bei Xu, Rutai Hui, Yibo Wang Tags: High Blood Pressure, Cognitive Impairment, Ischemic Stroke Original Contributions Source Type: research

Microbiological Etiologies of Pneumonia Complicating Stroke [Clinical Sciences]
Conclusions—Although the analysis was limited by small and heterogeneous study populations, limiting determination of microbiological causality, this review suggests aerobic Gram-negative bacilli and Gram-positive cocci are frequently associated with pneumonia complicating stroke. This supports the need for appropriately designed studies to determine microbial cause and a consensus-based approach in antibiotic usage and further targeted antibiotic treatment trials for enhanced antibiotic stewardship. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Amit K. Kishore, Andy Vail, Adam R. Jeans, Angel Chamorro, Mario Di Napoli, Lalit Kalra, Peter Langhorne, Christine Roffe, Willeke Westendorp, Paul J. Nederkoorn, Javier Garau, Diederik van de Beek, Joan Montaner, Mark Woodhead, Andreas Meisel, Craig J. S Tags: Complications, Meta Analysis, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Characterization of Heterozygous HTRA1 Mutations in Taiwanese Patients With Cerebral Small Vessel Disease [Clinical Sciences]
Conclusions—Heterozygous HTRA1 mutations account for 2.08% (7 of 337) of SVD in Taiwan. The clinical and neuroradiological features of HTRA1-related SVD and sporadic SVD are similar. These findings broaden the mutational spectrum of HTRA1 and highlight the pathogenic role of heterozygous HTRA1 mutations in SVD. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Yi-Chung Lee, Chih-Ping Chung, Nai-Chen Chao, Jong-Ling Fuh, Feng-Chi Chang, Bing-Wing Soong, Yi-Chu Liao Tags: Genetics, CADASIL, Neurogenesis Original Contributions Source Type: research

Risk of Ischemic and Hemorrhagic Strokes in Occult and Manifest Cancers [Clinical Sciences]
Conclusions—Cancer, occult and manifest, is associated with increased risks for stroke. The increased risk is linked mainly to cancers related to smoking. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Klaus Kaae Andersen, Tom Skyhoȷ Olsen Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Stroke: Highlights of Selected Articles [Stroke: Highlights of Selected Articles]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Tags: Secondary Prevention, Anticoagulants, Cerebrovascular Procedures, Ischemic Stroke Stroke: Highlights of Selected Articles Source Type: research

Distal Vessel Occlusions [Editorials]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Wolfgang G. Kunz, Mohammed A. Almekhlafi, Mayank Goyal Tags: Revascularization, Cerebrovascular Disease/Stroke, Ischemic Stroke, Embolism Editorial Source Type: research

Response by Loos et al to Letter Regarding Article, “Long-Term Morphological Changes of Symptomatic Lacunar Infarcts and Surrounding White Matter on Structural Magnetic Resonance Imaging” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Caroline M.J. Loos, Julie Staals, Joanna M. Wardlaw Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Letters to the Editor Source Type: research

Letter by Ryan et al Regarding Article, “Long-Term Morphological Changes of Symptomatic Lacunar Infarcts and Surrounding White Matter on Structural Magnetic Resonance Imaging” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Dan J. Ryan, Daniel R. Collins, Joseph A. Harbison Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Letters to the Editor Source Type: research

Letter by Trinh-Duc et al Regarding Article, “2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Albert Trinh-Duc, Meissa Kare, Mohamed Boudissa Tags: Revascularization, Health Services, Quality and Outcomes, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures Letters to the Editor Source Type: research

Response by Ducroux et al to Letter Regarding Article, “Thrombus Neutrophil Extracellular Traps Content Impair tPA-Induced Thrombolysis in Acute Ischemic Stroke” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Celina Ducroux, Jean-Philippe Desilles, Benoit Ho-Tin-Noe Tags: Inflammation, Pathophysiology, Cerebrovascular Procedures, Ischemic Stroke Letters to the Editor Source Type: research

Letter by van de Graaf et al Regarding Article, “Thrombus Neutrophil Extracellular Traps Content Impair tPA-Induced Thrombolysis in Acute Ischemic Stroke” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Rob A. van de Graaf, Heleen M.M. van Beusekom, Bob Roozenbeek Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Thrombosis Letters to the Editor Source Type: research

Response by Lorenzano et al to Letter Regarding Article, “Oxidative Stress Biomarkers of Brain Damage: Hyperacute Plasma F2-Isoprostane Predicts Infarct Growth in Stroke” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Svetlana Lorenzano, Natalia S. Rost, Karen L. Furie Tags: Cerebrovascular Disease/Stroke Letters to the Editor Source Type: research

Letter by Tsuda Regarding Article, “Oxidative Stress Biomarkers of Brain Damage: Hyperacute Plasma F2-Isoprostane Predicts Infarct Growth in Stroke” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Kazushi Tsuda Tags: Ischemic Stroke Letters to the Editor Source Type: research

Letter by Singh et al Regarding Article, “Imaging Characteristics of Venous Parenchymal Abnormalities” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Ravinder-Jeet Singh, Girish Baburao Kulkarni Tags: Cerebrovascular Disease/Stroke, Thrombosis Letters to the Editor Source Type: research

Clinical Performance Measures for Adults Hospitalized With Intracerebral Hemorrhage: Performance Measures for Healthcare Professionals From the American Heart Association/American Stroke Association [AHA/ASA Performance Measures]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: J. Claude Hemphill III, Opeolu M. Adeoye, David N. Alexander, Anne W. Alexandrov, Sepideh Amin-Hanjani, Mary Cushman, Mary G. George, Peter D. LeRoux, Stephan A. Mayer, Adnan I. Qureshi, Jeffrey L. Saver, Lee H. Schwamm, Kevin N. Sheth, David Tirschwell Tags: Statements and Guidelines AHA/ASA Performance Measures Source Type: research

Metric-Based Virtual Reality Simulation [InterSECT]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Thomas Liebig, Markus Holtmannspotter, Robert Crossley, Johan Lindkvist, Patrick Henn, Lars Lonn, Anthony G. Gallagher Tags: Cerebrovascular Procedures, Ischemic Stroke InterSECT Source Type: research

Acupuncture for Acute Stroke [Cochrane Corner]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Mangmang Xu, Dan Li, Shihong Zhang Tags: Quality and Outcomes, Intracranial Hemorrhage, Ischemic Stroke Cochrane Corner Source Type: research

Factor Xa Inhibitors Versus Vitamin K Antagonists for Prevention of Cerebral or Systemic Embolism in Patients With Atrial Fibrillation [Cochrane Corner]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Karsten M.H. Bruins Slot, Eivind Berge Tags: Atrial Fibrillation, Anticoagulants, Cerebrovascular Disease/Stroke Cochrane Corner Source Type: research

Role of Autophagy in Endothelial Damage and Blood-Brain Barrier Disruption in Ischemic Stroke [Basic Science Advances for Clinicians]
(Source: Stroke)
Source: Stroke - May 25, 2018 Category: Neurology Authors: Kyeong-A Kim, Donggeun Shin, Jeong-Hyeon Kim, Young-Jun Shin, G.K. Rajanikant, Arshad Majid, Seung-Hoon Baek, Ok-Nam Bae Tags: Endothelium/Vascular Type/Nitric Oxide, Blood-Brain Barrier, Cerebrovascular Disease/Stroke, Ischemic Stroke Basic Science Advances for Clinicians Source Type: research

Stem Cell-Based Immunomodulation After Stroke [Topical Review]
(Source: Stroke)
Source: Stroke - May 25, 2018 Category: Neurology Authors: Marieke C.S. Boshuizen, Gary K. Steinberg Tags: Inflammation, Stem Cells, Ischemic Stroke Topical Reviews Source Type: research

Imaging Endophenotypes of Stroke as a Target for Genetic Studies [Topical Review]
(Source: Stroke)
Source: Stroke - May 25, 2018 Category: Neurology Authors: Xueqiu Jian, Myriam Fornage Tags: Genetic, Association Studies, Genetics, Cerebrovascular Disease/Stroke, Ischemic Stroke Topical Reviews Source Type: research