Targeting Reperfusion Injury in the Age of Mechanical Thrombectomy [Basic Science Advances for Clinicians]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Atsushi Mizuma, Je Sung You, Midori A. Yenari Tags: Animal Models of Human Disease, Basic Science Research, Inflammation, Oxidant Stress Basic Science Advances for Clinicians Source Type: research

Role of Brain and Vessel Imaging for the Evaluation of Transient Ischemic Attack and Minor Stroke [Topical Review]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: A.Y.X. Yu, S.B. Coutts Tags: Ischemic Stroke, Transient Ischemic Attack (TIA) Topical Reviews Source Type: research

Blood Pressure in Acute Stroke [Topical Review]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Philip M. Bath, Jason P. Appleton, Kailash Krishnan, Nikola Sprigg Tags: High Blood Pressure, Intracranial Hemorrhage, Ischemic Stroke Topical Reviews Source Type: research

Trials and Frontiers in Carotid Endarterectomy and Stenting [Topical Review]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Douglas W. Jones, Thomas G. Brott, Marc L. Schermerhorn Tags: Revascularization, Stent, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Stenosis Topical Reviews Source Type: research

William M. Feinberg Award for Excellence in Clinical Stroke [Special Reports]
(Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Joanna M. Wardlaw Tags: Blood-Brain Barrier, Cerebrovascular Disease/Stroke, Ischemic Stroke Special Report Source Type: research

Stroke 112 [Brief Report]
Conclusions—Stroke 112, a universal stroke educational program without language barriers was developed. It could potentially be implemented worldwide, especially where 112 is used as an emergency phone number. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Jing Zhao, Maryellen F. Eckenhoff, Wei-Zen Sun, Renyu Liu Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Continuation or Discontinuation of Anticoagulation in the Early Phase After Acute Ischemic Stroke [Brief Report]
Background and Purpose—There is no consensus on whether anticoagulation should be continued or temporarily stopped in patients suffering acute ischemic stroke while using anticoagulation. We assessed treatment variations and outcomes in these patients.Methods—Post hoc analysis of PASS (Preventive Antibiotics in Stroke Study). We included patients with acute ischemic stroke who used anticoagulation at admission. We compared clinical outcomes, thrombotic, and major bleeding events at 3 months.Results—Nine percent (192/2101) of the patients with acute ischemic stroke used anticoagulation at admission (186 vitamin K anta...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Adrien E. Groot, Jan-Dirk M. Vermeij, Willeke F. Westendorp, Paul J. Nederkoorn, Diederik van de Beek, Jonathan M. Coutinho Tags: Secondary Prevention, Anticoagulants, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Nonconvulsive Status Epilepticus in Acute Intracerebral Hemorrhage [Brief Report]
Conclusions—NCSE is not a rare complication of acute ICH. Craniotomy and lobar involvement are independently associated with NCSE in patients with acute ICH. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Soichiro Matsubara, Shoichiro Sato, Tomohiro Kodama, Satoshi Egawa, Hidetoshi Nakamoto, Kazunori Toyoda, Yuichi Kubota Tags: Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Brief Reports Source Type: research

Neurologic Outcome Predictors in Pediatric Intracerebral Hemorrhage [Brief Report]
Background and Purpose—Intracerebral hemorrhage is a considerable source of morbidity and mortality. This 3-center study describes outcomes of pediatric intracerebral hemorrhage and identifies 2-year neurological outcome predictors.Methods—Children 29 days to 18 years of age presenting with intracerebral hemorrhage from March 2007 to May 2015 were enrolled prospectively. Exclusion criteria included trauma; intracranial tumor; hemorrhagic transformation of arterial ischemic stroke or cerebral sinovenous thrombosis; isolated subdural, epidural, or subarachnoid hemorrhage; and abnormal baseline neurological function. Intr...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Giulia S. Porcari, Lauren A. Beslow, Rebecca N. Ichord, Daniel J. Licht, Jonathan T. Kleinman, Lori C. Jordan Tags: Pediatrics, Prognosis, Mortality/Survival, Intracranial Hemorrhage Brief Reports Source Type: research

Antiplatelet Therapy, Cerebral Microbleeds, and Intracerebral Hemorrhage [Brief Report]
Conclusions—Antiplatelet drug use was associated with increased risk of strictly lobar MBs and increased the intracerebral hemorrhage incidence in participants with CMBs. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Jianting Qiu, Huirong Ye, Jialiang Wang, Jiangzhi Yan, Jian Wang, Yujie Wang Tags: Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Brief Reports Source Type: research

Low Serum Calcium and Magnesium Levels and Rupture of Intracranial Aneurysms [Brief Report]
Conclusions—In this large case–control study, hypocalcemia and hypomagnesemia at diagnosis were significantly associated with ruptured aneurysms. Impaired hemostasis caused by hypocalcemia and hypomagnesemia may explain this association. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Anil Can, Robert F. Rudy, Victor M. Castro, Dmitriy Dligach, Sean Finan, Sheng Yu, Vivian Gainer, Nancy A. Shadick, Guergana Savova, Shawn Murphy, Tianxi Cai, Scott T. Weiss, Rose Du Tags: Risk Factors, Cerebral Aneurysm Brief Reports Source Type: research

Early Cerebral Vein After Endovascular Ischemic Stroke Treatment Predicts Symptomatic Reperfusion Hemorrhage [Brief Report]
Conclusions—ECV on postendovascular mechanical thrombectomy digital subtraction angiography is highly diagnostic of subsequent symptomatic reperfusion hemorrhage in this data set. This finding has important implications for post-treatment management of blood pressure and anticoagulation. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Samuel C.D. Cartmell, Robyn L. Ball, Rajani Kaimal, Nicholas A. Telischak, Michael P. Marks, Huy M. Do, Robert L. Dodd, Gregory W. Albers, Maarten G. Lansberg, Jeremy J. Heit Tags: Cerebrovascular Procedures, Intracranial Hemorrhage, Ischemic Stroke Brief Reports Source Type: research

Elevated Plasma D-Dimer Level Is Associated With Short-Term Risk of Ischemic Stroke in Patients With Acute Heart Failure [Brief Report]
We examined 721 consecutive hospitalized AHF patients with plasma D-dimer level on admission from our prospective registry between January 2013 and May 2016. The study end points were incidence of ischemic stroke during hospitalization and at 30 days after admission.Results—Of the total participants (mean age, 76 years; male, 60%; atrial fibrillation, 54%; mean left ventricular ejection fraction, 38%), in-hospital ischemic stroke occurred in 18 patients (2.5%) during a median hospitalization period of 21 days, and 30-day ischemic stroke occurred in 16 patients (2.2%). Higher D-dimer level on admission was an independent ...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Yasuhiro Hamatani, Toshiyuki Nagai, Michikazu Nakai, Kunihiro Nishimura, Yasuyuki Honda, Hiroki Nakano, Satoshi Honda, Naotsugu Iwakami, Yasuo Sugano, Yasuhide Asaumi, Takeshi Aiba, Teruo Noguchi, Kengo Kusano, Kazunori Toyoda, Satoshi Yasuda, Hiroyuki Yo Tags: Heart Failure, Ischemic Stroke Brief Reports Source Type: research

Cardiovascular and Cerebrovascular Mortality Associated With Acute Exposure to PM2.5 in Mexico City [Brief Report]
Background and Purpose—Acute exposure to particulate matter with aerodynamic diameter (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Ivan Gutierrez–Avila, Leonora Roȷas–Bracho, Horacio Rioȷas–Rodriguez, Itai Kloog, Allan C. Just, Stephen J. Rothenberg Tags: Cardiovascular Disease, Epidemiology, Heart Failure, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Protective Effects of Brain Infarction by N-Acetylcysteine Derivatives [Basic Sciences]
Conclusions—The results indicate that detoxification of acrolein by NAC derivatives is caused through glutathione conjugation with acrolein catalyzed by glutathione S-transferases, which can be stabilized by NAC derivatives. This is a new concept of acrolein detoxification by NAC derivatives. (Source: Stroke)
Source: Stroke - June 25, 2018 Category: Neurology Authors: Takeshi Uemura, Kenta Watanabe, Kenta Ko, Kyohei Higashi, Noriyuki Kogure, Mariko Kitajima, Hiromitsu Takayama, Koichi Takao, Yoshiaki Sugita, Akihiko Sakamoto, Yusuke Terui, Toshihiko Toida, Keiko Kashiwagi, Kazuei Igarashi Tags: Animal Models of Human Disease, Ischemia, Oxidant Stress, Ischemic Stroke Original Contributions Source Type: research