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What Do Experimental Models Teach Us About Comorbidities in Stroke? [Basic Sciences Advances for Clinicians]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Sunghee Cho, Jiwon Yang Tags: Basic Science Research, Inflammation, Ischemic Stroke Basic Sciences Advances for Clinicians Source Type: research

Enlightenment and Challenges Offered by DAWN Trial (DWI or CTP Assessment With Clinical Mismatch in the Triage of Wake Up and Late Presenting Strokes Undergoing Neurointervention With Trevo) [Emerging Therapy Critique]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Gustavo Saposnik, Daniel Strbian Tags: Mortality/Survival, Ischemic Stroke Emerging Therapy Critiques Source Type: research

Diagnosis of Cerebral Amyloid Angiopathy [Topical Review]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Steven M. Greenberg, Andreas Charidimou Tags: Diagnostic Testing, Magnetic Resonance Imaging (MRI), Intracranial Hemorrhage Topical Reviews Source Type: research

Cognitive and Mood Assessment Tools for Use in Stroke [Topical Review]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Terence J. Quinn, Emma Elliott, Peter Langhorne Tags: Quality and Outcomes, Cognitive Impairment Topical Reviews Source Type: research

Surgical Management of Moyamoya Disease [Topical Review]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Guliz Acker, Lucius Fekonȷa, Peter Vaȷkoczy Tags: Cerebrovascular Disease/Stroke, Moyamoya Topical Reviews Source Type: research

Cerebrovascular Disease Knowledge Portal [Topical Review]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Katherine M. Crawford, Cristina Gallego-Fabrega, Christina Kourkoulis, Laura Miyares, Sandro Marini, Jason Flannick, Noel P. Burtt, Marcin von Grotthuss, Benjamin Alexander, Maria C. Costanzo, Neil H. Vaishnav, Rainer Malik, Jennifer L. Hall, Michael Chon Tags: Genetic, Association Studies, Genetics, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Topical Reviews Source Type: research

Historical Slavery and Modern-Day Stroke Mortality in the United States Stroke Belt [Comments and Opinions]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Charles Esenwa, Daudet Ilunga Tshiswaka, Mulugeta Gebregziabher, Bruce Ovbiagele Tags: Epidemiology, Race and Ethnicity, Risk Factors, Mortality/Survival, Cerebrovascular Disease/Stroke Comments and Opinions Source Type: research

Contact Aspiration Versus Stent Retriever in Patients With Acute Ischemic Stroke With M2 Occlusion in the ASTER Randomized Trial (Contact Aspiration Versus Stent Retriever for Successful Revascularization) [Brief Report]
Conclusions—First-line mechanical thrombectomy with CA compared with SR did not result in an increased successful revascularization rate in patients with acute stroke with isolated M2 occlusion. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Benjamin Gory, Bertrand Lapergue, Raphael Blanc, Julien Labreuche, Malek Ben Machaa, Alain Duhamel, Gautier Marnat, Suzana Saleme, Vincent Costalat, Serge Bracard, Hubert Desal, Mikael Mazighi, Arturo Consoli, Michel Piotin, for the ASTER Trial Investiga Tags: Revascularization, Stent, Treatment, Complications, Ischemic Stroke Brief Reports Source Type: research

Detection of Anterior Circulation Large Artery Occlusion in Ischemic Stroke Using Noninvasive Cerebral Oximetry [Brief Report]
Background and Purpose—Large artery occlusion (LAO) in ischemic stroke requires recognition and triage to an endovascular stroke treatment center. Noninvasive LAO detection is needed to improve triage.Methods—Prospective study to test whether noninvasive cerebral oximetry can detect anterior circulation LAO in acute stroke. Interhemispheric ΔBrSO2 in LAO was compared with controls.Results—In LAO stroke, mean interhemispheric ΔBrSO2 was −8.3±5.8% (n=19), compared with 0.4±5.8% in small artery stroke (n=17), 0.4±6.0% in hemorrhagic stroke (n=14), and 0.2±7.5% in...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Alexander C. Flint, Shiv G. Bhandari, Sean P. Cullen, Adhikari V. Reddy, Daniel P. Hsu, Vivek A. Rao, Minal Patel, Jasmeen Pombra, Nancy J. Edwards, Sheila L. Chan Tags: Revascularization, Ischemic Stroke Brief Reports Source Type: research

Relationship Between Dietary Vitamin D and Deaths From Stroke and Coronary Heart Disease [Brief Report]
Background and Purpose—There is growing evidence about the importance of vitamin D for cardiovascular health. Therefore, we examined the relationship between dietary vitamin D intake and risk of mortality from stroke and coronary heart disease in Japanese population.Methods—A prospective study encompassing 58 646 healthy Japanese adults (23 099 men and 35 547 women) aged of 40 to 79 years in whom dietary vitamin D intake was determined via a self-administered food frequency questionnaire. The median follow-up period was 19.3 years (1989–2009). The hazard ratios and 95% confidence intervals o...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Haytham A. Sheerah, Ehab S. Eshak, Renzhe Cui, Hironori Imano, Hiroyasu Iso, Akiko Tamakoshi Tags: Cardiovascular Disease, Diet and Nutrition, Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Intracranial Aneurysm-Associated Single-Nucleotide Polymorphisms Alter Regulatory DNA in the Human Circle of Willis [Basic Science]
Conclusions—CoW regulatory regions link IA-associated SNPs to genes with a potential role in the development of IAs. Our data refine previous predictions on SNPs associated with IA and provide a substantial resource from which candidates for follow-up studies can be prioritized. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Melanie D. Laarman, Marit W. Vermunt, Rachel Kleinloog, Jelkȷe J. de Boer–Bergsma, Netherlands Brain Bank, Gabriel J.E. Rinkel, Menno P. Creyghton, Michal Mokry, Jeroen Bakkers, Ynte M. Ruigrok Tags: Computational Biology, Epigenetics, Gene Expression & Regulation, Cerebral Aneurysm, Intracranial Hemorrhage Original Contributions Source Type: research

Impact of Prehospital Triage Scales to Detect Large Vessel Occlusion on Resource Utilization and Time to Treatment [Clinical Sciences]
Conclusions—Implementation of prehospital triage based on stroke severity scales would have strong impact on patient flow and distribution. The benefit of earlier thrombectomy for patients with LVO may outweigh the harm associated with delayed access to thrombolysis for some patients without LVO. Randomized trials using clinical stroke severity scales as a triage tool are needed to confirm our findings. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Ludwig Schlemm, Martin Ebinger, Christian H. Nolte, Matthias Endres Tags: Revascularization, Health Services, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Neuroimaging Identifies Patients Most Likely to Respond to a Restorative Stroke Therapy [Clinical Sciences]
Background and Purpose—Patient heterogeneity reduces statistical power in clinical trials of restorative therapies. Valid predictors of treatment responsiveness are needed, and several have been studied with a focus on corticospinal tract (CST) injury. We studied performance of 4 such measures for predicting behavioral gains in response to motor training therapy.Methods—Patients with subacute-chronic hemiparetic stroke (n=47) received standardized arm motor therapy, and change in arm Fugl-Meyer score was calculated from baseline to 1 month post-therapy. Injury measures calculated from baseline magnetic resonanc...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Jessica M. Cassidy, George Tran, Erin B. Quinlan, Steven C. Cramer Tags: Biomarkers, Imaging, Rehabilitation, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Efficacy and Safety of Individualized Coaching After Stroke: the LAST Study (Life After Stroke) [Clinical Sciences]
Background and Purpose—The evidence for interventions to prevent functional decline in the long term after stroke is lacking. The aim of this trial was to evaluate the efficacy and safety of an 18-month follow-up program of individualized regular coaching on physical activity and exercise.Methods—This was a multicentre, pragmatic, single-blinded, randomized controlled trial. Adults (age ≥18 years) with first-ever or recurrent stroke, community dwelling, with modified Rankin Scale (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Torunn Askim, Birgitta Langhammer, Hege Ihle-Hansen, Mari Gunnes, Stian Lydersen, Bent Indredavik, on behalf of the LAST Collaboration Group* Tags: Exercise, Lifestyle, Secondary Prevention, Compliance/Adherence, Rehabilitation Original Contributions Source Type: research

Carotid Atheroma From Men Has Significantly Higher Levels of Inflammation and Iron Metabolism Enabled by Macrophages [Clinical Sciences]
Conclusions—Male patients with carotid atheroma had more advanced and ruptured lesions associated with significantly higher levels of inflammatory macrophage infiltration and high iron stores in the blood and in their plaques. These findings help to understand sex differences and iron metabolism in atherosclerosis and factors related to atheroma progression. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Xi-Ming Yuan, Liam J. Ward, Claes Forssell, Nabeel Siraj, Wei Li Tags: Inflammation, Oxidant Stress, Pathophysiology, Proteomics, Atherosclerosis Original Contributions Source Type: research

Closure of Patent Foramen Ovale Versus Medical Therapy in Patients With Cryptogenic Stroke or Transient Ischemic Attack [Clinical Sciences]
Conclusions—In patients with cryptogenic stroke/TIA and PFO who have their PFO closed, ischemic stroke recurrence is less frequent compared with patients receiving medical treatment. Atrial fibrillation is more frequent but mostly transient. There is no difference in TIA, all-cause mortality, or myocardial infarction. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: George Ntaios, Vasileios Papavasileiou, Dimitrios Sagris, Konstantinos Makaritsis, Konstantinos Vemmos, Thorsten Steiner, Patrik Michel Tags: Ischemic Stroke Original Contributions Source Type: research

Improving Access to Thrombolysis and Inhospital Management Times in Ischemic Stroke [Clinical Sciences]
Conclusions—An interactive and multifaceted training program targeting emergency professionals was significantly associated with an increased access to thrombolysis, especially within 4 hours and 30 minutes.Clinical Trial Registration—URL: https://www.clinicaltrials.gov. Unique identifier: NCT02814760. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Julie Haesebaert, Norbert Nighoghossian, Catherine Mercier, Anne Termoz, Sylvie Porthault, Laurent Derex, Pierre-Yves Gueugniaud, Estelle Bravant, Muriel Rabilloud, Anne-Marie Schott, on behalf of the AVC II Trial group* Tags: Health Services, Quality and Outcomes, Ischemic Stroke Original Contributions Source Type: research

STARTING-SICH Nomogram to Predict Symptomatic Intracerebral Hemorrhage After Intravenous Thrombolysis for Stroke [Clinical Sciences]
Background and Purpose—Symptomatic intracerebral hemorrhage (sICH) is a rare but the most feared complication of intravenous thrombolysis for ischemic stroke. We aimed to develop and validate a nomogram for individualized prediction of sICH in intravenous thrombolysis–treated stroke patients included in the multicenter SITS-ISTR (Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register).Methods—All patients registered in the SITS-ISTR by 179 Italian centers between May 2001 and March 2016 were originally included. The main outcome measure was sICH per the European Cooperati...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Manuel Cappellari, Gianni Turcato, Stefano Forlivesi, Cecilia Zivelonghi, Paolo Bovi, Bruno Bonetti, Danilo Toni Tags: Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Associations Between Collateral Status and Thrombus Characteristics and Their Impact in Anterior Circulation Stroke [Clinical Sciences]
Conclusions—Patients with lower thrombus burden and higher thrombus perviousness scores had higher collateral score. The positive effect of thrombus perviousness on clinical outcome was only present in patients with moderate and high collateral scores.Clinical Trial Registration—URL: http://www.trialregister.nl. Unique identifier: NTR1804 and URL: http://www.controlled-trials.com Unique identifier: ISRCTN10888758. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Heitor C. Alves, Kilian M. Treurniet, Bruna G. Dutra, Ivo G. H. Jansen, Anna M.M. Boers, Emilie M.M. Santos, Olvert A. Berkhemer, Diederik W.J. Dippel, Aad van der Lugt, Wim H. van Zwam, Robert J. van Oostenbrugge, Hester F. Lingsma, Yvo B.W.E.M. Roos, Al Tags: Computerized Tomography (CT), Ischemic Stroke Original Contributions Source Type: research

Transient Ischemic Attack Results in Delayed Brain Atrophy and Cognitive Decline [Clinical Sciences]
Background and Purpose—Transient ischemic attack (TIA) initiates an ischemic cascade without resulting in frank infarction and, as such, represents a novel model to study the effects of this ischemic cascade and secondary neurodegeneration in humans.Methods—Patients with suspected TIA underwent acute brain perfusion imaging, and those with acute ischemia were enrolled into a prospective observational study. We collected baseline and 90-day magnetic resonance imaging, including MP-RAGE (high-resolution T1 sequence) and cognitive assessment with the Montreal Cognitive Assessment. Brain morphometry and within pati...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Andrew Bivard, Thomas Lillicrap, Benedicte Marechal, Carlos Garcia–Esperon, Elizabeth Holliday, Venkatesh Krishnamurthy, Christopher R. Levi, Mark Parsons Tags: Clinical Studies, Magnetic Resonance Imaging (MRI), Blood-Brain Barrier, Cognitive Impairment, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Serum Hepatocyte Growth Factor Is Probably Associated With 3-Month Prognosis of Acute Ischemic Stroke [Clinical Sciences]
Background and Purpose—Serum hepatocyte growth factor (HGF) is positively associated with poor prognosis of heart failure and myocardial infarction, and it can also predict the risk of ischemic stroke in population. The goal of this study was to investigate the association between serum HGF and prognosis of ischemic stroke.Methods—A total of 3027 acute ischemic stroke patients were included in this post hoc analysis of the CATIS (China Antihypertensive Trial in Acute Ischemic Stroke). The primary outcome was composite outcome of death or major disability (modified Rankin Scale score ≥3) within 3 months.Resul...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Zhengbao Zhu, Tan Xu, Daoxia Guo, Xinfeng Huangfu, Chongke Zhong, Jingyuan Yang, Aili Wang, Chung-Shiuan Chen, Yanbo Peng, Tian Xu, Jinchao Wang, Yingxian Sun, Hao Peng, Qunwei Li, Zhong Ju, Deqin Geng, Jing Chen, Yonghong Zhang, Jiang He Tags: Biomarkers, Clinical Studies, Epidemiology, Prognosis, Ischemic Stroke Original Contributions Source Type: research

Modeling the Impact of Interhospital Transfer Network Design on Stroke Outcomes in a Large City [Clinical Sciences]
Conclusions—Optimizing acute stroke transfer networks resulted in clinically small changes in population-level stroke outcomes in a dense, urban area. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Neal S. Parikh, Abhinaba Chatterȷee, Ivan Diaz, Ankur Pandya, Alexander E. Merkler, Gino Gialdini, Benȷamin R. Kummer, Saad A. Mir, Michael P. Lerario, Matthew E. Fink, Babak B. Navi, Hooman Kamel Tags: Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Revised Framingham Stroke Risk Score, Nontraditional Risk Markers, and Incident Stroke in a Multiethnic Cohort [Clinical Sciences]
Conclusions—The R-FSRS downgraded stroke risk but had better calibration and discriminative ability for incident stroke compared with the original FSRS. Nontraditional risk markers modestly improved the discriminative ability of the R-FSRS, with coronary artery calcium performing the best. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Peter Flueckiger, Will Longstreth, David Herrington, Joseph Yeboah Tags: Epidemiology, Primary Prevention, Race and Ethnicity, Risk Factors, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Periodontal Disease, Regular Dental Care Use, and Incident Ischemic Stroke [Clinical Sciences]
Background and Purpose—Periodontal disease is independently associated with cardiovascular disease. Identification of periodontal disease as a risk factor for incident ischemic stroke raises the possibility that regular dental care utilization may reduce the stroke risk.Methods—In the ARIC (Atherosclerosis Risk in Communities) study, pattern of dental visits were classified as regular or episodic dental care users. In the ancillary dental ARIC study, selected subjects from ARIC underwent fullmouth periodontal measurements collected at 6 sites per tooth and classified into 7 periodontal profile classes (PPCs).Re...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Souvik Sen, Lauren D. Giamberardino, Kevin Moss, Thiago Morelli, Wayne D. Rosamond, Rebecca F. Gottesman, James Beck, Steven Offenbacher Tags: Cardiovascular Disease, Risk Factors, Cerebrovascular Disease/Stroke, Ischemic Stroke, Atherosclerosis Original Contributions Source Type: research

Association Between Hyperacute Stage Blood Pressure Variability and Outcome in Patients With Spontaneous Intracerebral Hemorrhage [Clinical Sciences]
Conclusions—BPV during the hyperacute first minutes and hours after onset in patients with intracerebral hemorrhage was independently associated with poor functional outcome. Stabilization of BPV during this vulnerable period, in the pre-hospital and early emergency department course, is a potential therapeutic target for future clinical trials.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00059332. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Pil-Wook Chung, Joon-Tae Kim, Nerses Sanossian, Sidney Starkmann, Scott Hamilton, Jeffrey Gornbein, Robin Conwit, Marc Eckstein, Frank Pratt, Sam Stratton, David S. Liebeskind, Jeffrey L. Saver Tags: High Blood Pressure, Intracranial Hemorrhage Original Contributions Source Type: research

Presence of Anterior Communicating Artery Aneurysm Is Associated With Age, Bifurcation Angle, and Vessel Diameter [Clinical Sciences]
The objective of this study was to investigate association of the Acom aneurysm formation with patient age and vascular bifurcation morphology.Methods—Three-dimensional angiographic data of 665 patients were used in this study, including 160 patients with Acom aneurysms, 66 with non-Acom aneurysms, and 439 control subjects with no aneurysms. The anterior cerebral artery bifurcation angle (Acom/A2 angle), arterial diameters, and Acom aneurysm geometric characters were examined.Results—Women of 50 to 70 years were more vulnerable to Acom aneurysm formation than men. The Acom/A2 bifurcation angle was significantly...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Xue-Jing Zhang, Bu-Lang Gao, Wei-Li Hao, Song-Shi Wu, Dong-Hai Zhang Tags: Basic Science Research, Vascular Biology, Vascular Disease Original Contributions Source Type: research

Predictors of In-Hospital Death After Aneurysmal Subarachnoid Hemorrhage [Clinical Sciences]
Background and Purpose—To identify predictors of in-hospital mortality in patients with aneurysmal subarachnoid hemorrhage and to estimate their impact.Methods—Retrospective analysis of prospective data from a nationwide multicenter registry on all aneurysmal subarachnoid hemorrhage cases admitted to a tertiary neurosurgical department in Switzerland (Swiss SOS [Swiss Study on Aneurysmal Subarachnoid Hemorrhage]; 2009–2015). Both clinical and radiological independent predictors of in-hospital mortality were identified, and their effect size was determined by calculating adjusted odds ratios (aORs) using m...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Martin Nikolaus Stienen, Menno Germans, Jan–Karl Burkhardt, Marian C. Neidert, Christian Fung, David Bervini, Daniel Zumofen, Michel Rothlisberger, Serge Marbacher, Rodolfo Maduri, Thomas Robert, Martin A. Seule, Philippe Biȷlenga, Karl Schal Tags: Mortality/Survival, Cerebral Aneurysm, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Original Contributions Source Type: research

Retrospective Methods Analysis of Semiautomated Intracerebral Hemorrhage Volume Quantification From a Selection of the STICH II Cohort (Early Surgery Versus Initial Conservative Treatment in Patients With Spontaneous Supratentorial Lobar Intracerebral Haematomas) [Clinical Sciences]
Conclusions—Although the ABC/2 formula for calculating elliptical ICH is well validated, it must be used with caution in ICH scans where the elliptical shape of ICH is a false assumption. We validated the adjustment of the ABC/2.4 method in randomization, antithrombotic-associated, heterogeneous-density, and irregular-shape ICH.Clinical Trial Registration—URL: http://www.isrctn.com/ISRCTN22153967. Unique identifier: ISRCTN22153967. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Mark D. Haley, Barbara A. Gregson, W. Andrew Mould, Daniel F. Hanley, Alexander David Mendelow Tags: Computerized Tomography (CT), Intracranial Hemorrhage Original Contributions Source Type: research

Association Between Heart Rate and Subclinical Cerebrovascular Disease in the Elderly [Clinical Sciences]
Conclusions—In a predominantly elderly cohort, elevated nighttime HR was associated with WMHV, suggesting an independent role of HR in subclinical cerebrovascular disease. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Koki Nakanishi, Zhezhen Jin, Shunichi Homma, Mitchell S.V. Elkind, Tatjana Rundek, Seitetz C. Lee, Aylin Tugcu, Mitsuhiro Yoshita, Charles DeCarli, Clinton B. Wright, Ralph L. Sacco, Marco R. Di Tullio Tags: Risk Factors, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Cerebrovascular Outcomes With Proton Pump Inhibitors and Thienopyridines [Clinical Sciences]
Background and Purpose—Pharmacokinetic and prior studies on thienopyridine and proton pump inhibitors (PPI) coadministration provide conflicting data for cardiovascular outcomes, whereas there is no established evidence on the association of concomitant use of PPI and thienopyridines with adverse cerebrovascular outcomes.Methods—We conducted a systematic review and meta-analysis of randomized controlled trials and cohort studies from inception to July 2017, reporting following outcomes among patients treated with thienopyridine and PPI versus thienopyridine alone (1) ischemic stroke, (2) combined ischemic or he...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Konark Malhotra, Aristeidis H. Katsanos, Mohammad Bilal, Muhammad Fawad Ishfaq, Nitin Goyal, Georgios Tsivgoulis Tags: Meta Analysis, Ischemic Stroke Original Contributions Source Type: research

Carotid Intima-Media Thickness Is Associated With White Matter Hyperintensities [Clinical Sciences]
Conclusions—Larger cIMT was associated with greater burden of cerebral WM lesions independently of demographics and traditional vascular risk factors, particularly among elderly and Hispanic participants, who are at high risk for stroke and cognitive decline. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: David Della-Morte, Chuanhui Dong, Matthew S. Markert, Mitchell S.V. Elkind, Ralph L. Sacco, Clinton B. Wright, Tatjana Rundek Tags: Epidemiology, Race and Ethnicity, Ultrasound Original Contributions Source Type: research

Comparison of Risk Factor Control in the Year After Discharge for Ischemic Stroke Versus Acute Myocardial Infarction [Clinical Sciences]
Background and Purpose—The Veterans Health Administration has engaged in quality improvement to improve vascular risk factor control. We sought to examine blood pressure ( (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Dawn M. Bravata, Joanne Daggy, Jared Brosch, Jason J. Sico, Fitsum Baye, Laura J. Myers, Christianne L. Roumie, Eric Cheng, Jessica Coffing, Greg Arling Tags: Ischemic Stroke Original Contributions Source Type: research

Stroke Incidence and Outcomes in Northeastern Greece [Clinical Sciences]
Conclusions—This is the largest to date population-based study in Greece documenting one of the highest stroke incidences ever reported in South Europe, highlighting the need for efficient stroke prevention and treatment strategies in Northeastern Greece. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Georgios Tsivgoulis, Athanasia Patousi, Maria Pikilidou, Theodosis Birbilis, Aristeidis H. Katsanos, Michalis Mantatzis, Aristeidis Asimis, Nikolaos Papanas, Panagiotis Skendros, Aikaterini Terzoudi, Aikaterini Karamanli, Ioannis Kouroumichakis, Pantelis Tags: Epidemiology, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Burden of Dilated Perivascular Spaces, an Emerging Marker of Cerebral Small Vessel Disease, Is Highly Heritable [Clinical Sciences]
Conclusions—We provide evidence for important genetic contribution to dPVS burden in older community-dwelling people, some of which may be shared with WMHV. Differential heritability patterns for dPVS in white matter and basal ganglia suggest at least partly distinct underlying biological processes. (Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Marie–Gabrielle Duperron, Christophe Tzourio, Muralidharan Sargurupremraȷ, Bernard Mazoyer, Aicha Soumare, Sabrina Schilling, Philippe Amouyel, Ganesh Chauhan, Yi–Cheng Zhu, Stephanie Debette Tags: Aging, Epidemiology, Genetics, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Stroke: Highlights of Selected Articles [Stroke: Highlights of Selected Articles]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Tags: Secondary Prevention, Quality and Outcomes, Ischemic Stroke Stroke: Highlights of Selected Articles Source Type: research

The LAST Word on Coaching as a Stroke Intervention? [Editorial]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Katie Gallacher, Terence J. Quinn Tags: Cerebrovascular Disease/Stroke Editorials Source Type: research

Transient Ischemic Attack and Minor Stroke [Editorial]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Dominique Deplanque, Michele Bastide, Regis Bordet Tags: Cognitive Impairment, Transient Ischemic Attack (TIA) Editorials Source Type: research

Optimal Blood Pressure After Intracerebral Hemorrhage [Editorial]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Alejandro A. Rabinstein Tags: Intracranial Hemorrhage Editorials Source Type: research

Ischemic Stroke Mandates Cross-Disciplinary Collaboration [Editorial]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Marc Fisher, Joseph A. Hill Tags: Atrial Fibrillation, Cardiovascular Disease, Secondary Prevention, Cerebrovascular Procedures Editorials Source Type: research

Richard Joel Traystman, PhD [In Memoriam]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Michael A. Moskowitz, Patrician D. Hurn, Costantino Iadecola Tags: Vascular Disease In Memoriam Source Type: research

Correction to: Enlightenment and Challenges Offered by DAWN Trial (DWI or CTP Assessment With Clinical Mismatch in the Triage of Wake Up and Late Presenting Strokes Undergoing Neurointervention With Trevo) [Corrections]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Tags: Correction Source Type: research

Response by Voelkel and Hubert to Letter Regarding Article, “Thrombolysis in Postoperative Stroke” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Nicolas Voelkel, Gordian Jan Hubert Tags: Treatment, Ischemic Stroke Letters to the Editor Source Type: research

Letter by Liu et al Regarding Article, “Thrombolysis in Postoperative Stroke” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Fujun Liu, Wei Chen, Jing Chen Tags: Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Letters to the Editor Source Type: research

Response by Li to Letter Regarding Article, “Island Sign: An Imaging Predictor for Early Hematoma Expansion and Poor Outcome in Patients With Intracerebral Hemorrhage” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Qi Li Tags: Intracranial Hemorrhage Letters to the Editor Source Type: research

Letter by Yu et al Regarding Article, “Island Sign: An Imaging Predictor for Early Hematoma Expansion and Poor Outcome in Patients With Intracerebral Hemorrhage” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Zhiyuan Yu, Jun Zheng, Chao You Tags: Intracranial Hemorrhage Letters to the Editor Source Type: research

Response by Miller to Letter Regarding Article, “Incorporating Nonphysician Stroke Specialists into the Stroke Team” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Eliza C. Miller Tags: Cerebrovascular Disease/Stroke Letters to the Editor Source Type: research

Letter by Cooper et al Regarding the Article, “Incorporating Nonphysician Stroke Specialists Into the Stroke Team” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Jon Cooper, Jennifer Tsui, Alastair Bailey Tags: Cerebrovascular Disease/Stroke, Transient Ischemic Attack (TIA) Letters to the Editor Source Type: research

Letter by Shiue and Sands Regarding Article, “Incorporating Nonphysician Stroke Specialists Into the Stroke Team” [Letter to the Editor]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Harn J. Shiue, Kara A. Sands Tags: Pharmacology, Cerebrovascular Disease/Stroke Letters to the Editor Source Type: research

Supplementary Motor Area Stroke Mimicking Functional Disorder [Illustrative Teaching Case]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Paul Mathew, Prem Pradeep Batchala, Thomas Jose Eluvathingal Muttikkal Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke, Atherosclerosis Illustrative Teaching Cases Source Type: research

New Horizons for Stroke Medicine: Understanding the Value of Social Media [InterSECT]
(Source: Stroke)
Source: Stroke - January 22, 2018 Category: Neurology Authors: Jose Maria Cabrera-Maqueda, Jatinder S. Minhas Tags: Ethics and Policy, Health Services, Statements and Guidelines, Intracranial Hemorrhage, Ischemic Stroke InterSECT Source Type: research