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Specialty: Neurology
Condition: Alcoholism

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Total 356 results found since Jan 2013.

No J-Shaped Curve for Alcohol and Stroke? No J-Shaped Curve for Alcohol and Stroke?
A new study has found no significant risk reduction for ischemic or hemorrhagic stroke with light to moderate midlife alcohol consumption, as well as increased risks at heavier intake levels. Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - October 2, 2015 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Prevalence of Stroke and Its Risk Factors in Urban Sri Lanka: Population-Based Study Brief Reports
Conclusions— Age-adjusted stroke prevalence in urban Sri Lanka lies between high-income and low-/middle-income countries. The prevalence of stroke and its risk factors were higher among men.
Source: Stroke - September 28, 2015 Category: Neurology Authors: Chang, T., Gajasinghe, S., Arambepola, C. Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Acute Cerebral Infarction Brief Reports Source Type: research

Acute Alcohol Intoxication Aggravates Brain Injury Caused by Intracerebral Hemorrhage in Rats
Alcohol intoxication is associated with worse intracerebral hemorrhage (ICH) outcome, indicating the important role of alcohol in ICH pathogenesis. We intended to investigate the effects of ethanol pretreatment on the severity of ICH-induced brain injury in rats.
Source: Journal of Stroke and Cerebrovascular Diseases - September 16, 2015 Category: Neurology Authors: Hock-Kean Liew, Hung-Yu Cheng, Li-Chuan Huang, Kuo-Wei Li, Hsiao-Fen Peng, Hui-I. Yang, Peter Bor-Chian Lin, Jon-Son Kuo, Cheng-Yoong Pang Source Type: research

Stroke incidence and risk factors in Havana and Matanzas, Cuba
Conclusions Stroke incidence was similar to rates reported in developed countries and lower than that in low- to middle-income countries. Given that diabetes mellitus, heart disease, arterial hypertension, smoking, APOE4, etc. are associated with higher mortality rates, they will require separate analysis in a study of stroke risk factors.
Source: Neurologia - September 12, 2015 Category: Neurology Source Type: research

Watch your neighbor's garden, or Delphi's oracle for unruptured intracranial aneurysm treatment
Current management recommendations for patients with unruptured intracranial aneurysms (UIAs) include surgical clipping, endovascular coiling, or noninterventional follow-up.1 Several population-based studies and meta-analyses identified risk factors associated with aneurysm growth and rupture,2 some of which are modifiable (arterial hypertension, smoking, and excessive alcohol consumption) and some of which are not (increasing age, female sex, ethnic origin, aneurysm size, and morphology); however, no randomized controlled data exist on the potential benefit of preventive intervention for UIAs. The multinational TEAM (Tri...
Source: Neurology - September 7, 2015 Category: Neurology Authors: Bijlenga, P., Stapf, C. Tags: All Cerebrovascular disease/Stroke EDITORIALS Source Type: research

Prognostic significance of homocysteine levels in acute ischemic stroke: A prospective cohort study.
Abstract Associations between hyperhomocysteinemia and prognosis of stroke were seldom explored and always indefinite. We therefore performed a study to elucidate the relationship between homocysteine levels and stroke prognosis. Between 2008 and 2013, baseline data and blood samples of acute ischemic stroke patients were collected from the Henan Province Stroke Registry. Using a prospective cohort, scheduled follow-up, and multivariable logistic regression analysis, associations among the blood homocysteine level and acute neurological impairment and outcomes, stroke recurrence, and all-cause death were investiga...
Source: Current Neurovascular Research - August 7, 2015 Category: Neurology Authors: Ji Y, Song B, Xu Y, Fang H, Wu J, Sun S, Zhao L, Shi C, Gao Y, Tao Y, Li Y Tags: Curr Neurovasc Res Source Type: research

Underuse of anticoagulation in stroke patients with atrial fibrillation – the FibStroke Study
ConclusionsUnderuse of anticoagulation is a common contributor to ischaemic strokes and TIA episodes in patients with AF. Infrequent AF episodes, previous bleeds, patient preference and alcohol abuse were the most common reasons for not using OAC.
Source: European Journal of Neurology - August 1, 2015 Category: Neurology Authors: A. Palomäki, P. Mustonen, J. E. K. Hartikainen, I. Nuotio, T. Kiviniemi, A. Ylitalo, P. Hartikainen, K. E. J. Airaksinen Tags: Original Article Source Type: research

A high burden of ischemic stroke in regions of Eastern/Central Europe is largely due to modifiable risk factors.
Abstract Incidence and mortality of ischemic stroke in Croatia is significantly higher than in many other developed European countries. Here, we aimed to evaluate underlying conditions of this unacceptably high ischemic stroke burden. An observational prospective cohort study of ) first-ever ischemic stroke patients identified in a population-based incidence study (N=751) (study 1, S1) and a concurrent case-control trial (215 patients, 125 controls, S2) were conducted in the country of Varazdin from 2007-2010. Atrial fibrillation (AF) was common (36.1% in S1, 40.9% in S2) and mostly (>50%) unrecognized before t...
Source: Current Neurovascular Research - July 30, 2015 Category: Neurology Authors: Pikija S, Trkulja V, Malojcic B, Mutzenbach JS, Sellner J Tags: Curr Neurovasc Res Source Type: research

Antithrombotic Treatment Following Intracerebral Hemorrhage in Patients With and Without Atrial Fibrillation Clinical Sciences
Conclusions— In majority of patients who receive antithrombotic agents, treatment is initiated within 6 months of ICH. Still, many patients with compelling indications for antithrombotic treatment are not prescribed antithrombotic agents. Factors other than high risk of embolic stroke by CHA2DS2-VASc in ICH survivors with concurrent AF are used to guide the anticoagulant treatment decision in Swedish clinical practice.
Source: Stroke - July 27, 2015 Category: Neurology Authors: Pennlert, J., Asplund, K., Carlberg, B., Wiklund, P.-G., Wisten, A., Asberg, S., Eriksson, M. Tags: Acute Cerebral Hemorrhage, Anticoagulants, Antiplatelets, Epidemiology Clinical Sciences Source Type: research

Adverse Outcomes After Initial Non-surgical Management of Subdural Hematoma: A Population-Based Study
Conclusions Approximately one in eight patients with a conservatively managed SDH was readmitted with SDH within 90 days. A substantial proportion of these readmissions involved surgical hematoma evacuation. These outcomes occurred significantly more often after nontraumatic as compared to traumatic SDH.
Source: Neurocritical Care - July 10, 2015 Category: Neurology Source Type: research

Sex Differences in Outcomes and Associated Risk Factors After Acute Ischemic Stroke in Elderly Patients: A Prospective Follow-up Study
Stroke has a greater effect on women. However, sex differences in outcome and factors associated with outcome among elderly patients are unknown. From January 2009 to December 2011, 810 patients with acute ischemic stroke aged 75 years or older were recruited in China. Clinical profile and risk factors were recorded. Outcomes and associated risk factors at 12 and 36 months after stroke were assessed by sex. Hypertension, diabetes mellitus, dyslipidemias, and obesity prevalence rates were higher in women than in men; opposite trends were found for smoking and alcohol consumption.
Source: Journal of Stroke and Cerebrovascular Diseases - July 10, 2015 Category: Neurology Authors: Bin Li, Tao Wang, Yongzhong Lou, Xiaofei Guo, Hongfei Gu, Yanxia Zhu, Xianjia Ning, Jinghua Wang, Jun Tu Source Type: research

Stroke - lifestyle and environment.
Abstract Lifestyle modifications and environmental factors are important for stroke prevention and rehabilitation after stroke. The individual stroke risk may be modified by factors like physical activity, body weight and nutrition, special dietary supplements such as vitamins, smoking, consumption of tea, coffee and alcohol, psychological factors and by keeping a pet. The focus of this article lies on measures for stroke prevention. For certain topics, it also comments on factors that are important during rehabilitation after stroke. PMID: 26105161 [PubMed - as supplied by publisher]
Source: Der Nervenarzt - June 25, 2015 Category: Neurology Authors: Gerischer LM, Flöel A, Endres M Tags: Nervenarzt Source Type: research

Primary prevention of stroke by a healthy lifestyle in a high-risk group
Conclusions: A healthy lifestyle is associated with a substantially reduced risk of stroke in men at higher risk of stroke.
Source: Neurology - June 1, 2015 Category: Neurology Authors: Larsson, S. C., Akesson, A., Wolk, A. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Cohort studies ARTICLE Source Type: research

Impact of Alcohol Consumption on the Outcome of Ischemic Stroke and Thrombolysis: Role of the Hepatic Clearance of Tissue-Type Plasminogen Activator Basic Sciences
Conclusions— An efficient liver-driven clearance of tPA might influence the safety of thrombolysis after stroke.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Lemarchand, E., Gauberti, M., Martinez de Lizarrondo, S., Villain, H., Repesse, Y., Montagne, A., Vivien, D., Ali, C., Rubio, M. Tags: Acute Cerebral Infarction, Thrombolysis Basic Sciences Source Type: research

KALRN Rare and Common Variants and Susceptibility to Ischemic Stroke in Chinese Han Population
In this study, we analyzed four KALRN gene SNPs in 503 ischemic stroke patients and 493 control subjects, separating the patients into separate research groups based on comorbidity with hypertension or diabetes and stroke type (atherosis or lacunar and combination type). We found a rare variant of KALRN, rs11712619, that associated with lacunar stroke in the northern Chinese Han population with an average-risk allele frequency 0.009 (OR 2.95, 95 % CI 1.08–8.01, p = 0.028). However, after adjusting for relevant factors, including sex, age, body mass index, dyslipidemia, alcohol consumption, and smoking, this associatio...
Source: NeuroMolecular Medicine - April 28, 2015 Category: Neurology Source Type: research