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Specialty: Neurology
Condition: Alcoholism

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Total 356 results found since Jan 2013.

Nonpsychotic Mental Disorders in Teenage Males and Risk of Early Stroke: A Population-Based Study Clinical Sciences
Conclusions— Our findings suggest that fitness may modify associations between nonpsychotic disorders and stroke. It remains to be clarified whether interventions designed to improve fitness in mentally ill youth can influence future risk of early stroke.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Aberg, M. A. I., Toren, K., Nilsson, M., Henriksson, M., Kuhn, H. G., Nyberg, J., Rosengren, A., Aberg, N. D., Waern, M. Tags: Epidemiology, Risk Factors, Cerebral Aneurysm, Intracranial Hemorrhage, Ischemic Stroke Clinical Sciences Source Type: research

Association between interleukin-6 (G174C and C572G) promoter gene polymorphisms and risk of ischemic stroke in North Indian population: a case-control study.
CONCLUSION: Our results suggest that IL-6 (G174C) polymorphism is significantly associated with the risk of IS in North Indian population. However, IL-6 (C572G) polymorphism is found significantly associated with the risk of IS after adjusting the demographic and risk factors variables. Prospective studies with large sample size are required for independent validation. Our findings could be helpful in identifying individuals at increased risk for developing IS. PMID: 26883819 [PubMed - as supplied by publisher]
Source: Neurological Research - February 18, 2016 Category: Neurology Tags: Neurol Res Source Type: research

Household Secondhand Smoke Exposure Confers Higher Stroke Risk and Poorer Stroke Prognosis (S42.005)
CONCLUSIONS: Household SHS is associated with a 1.5-fold increase in stroke risk and a 2-fold increase in mortality after stroke among never-smokers. While prospective studies are needed to assess causality, this study highlights the importance of obtaining SHS exposure history and counseling patients and their families on the potential impact of SHS on post-stroke outcomes.Disclosure: Dr. Lin has nothing to disclose. Dr. Ovbiagele has nothing to disclose. Dr. Markovic has nothing to disclose. Dr. Towfighi has nothing to disclose.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Lin, M., Ovbiagele, B., Markovic, D., Towfighi, A. Tags: Stroke Mechanism and Modifiers Source Type: research

Use of Warfarin at Discharge Among Acute Ischemic Stroke Patients With Nonvalvular Atrial Fibrillation in China Clinical Sciences
Conclusions— The rate of warfarin use remains low among patients with ischemic stroke and known nonvalvular atrial fibrillation in China. Hospital size and academic status together with patient age, heart failure, heavy alcohol drinking, international normalized ratio in hospital, and stroke severity on admission were each independently associated with the use of warfarin at discharge. There is much room for improvement for secondary stroke prevention in nonvalvular atrial fibrillation patients in China.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Yang, X., Li, Z., Zhao, X., Wang, C., Liu, L., Wang, C., Pan, Y., Li, H., Wang, D., Hart, R. G., Wang, Y., Wang, Y., on behalf of the China National Stroke Registry II Investigators Tags: Anticoagulants, Treatment, Quality and Outcomes, Ischemic Stroke Clinical Sciences Source Type: research

Lifestyle modification for stroke prevention: facts and fiction
Purpose of review: The purpose is to summarize recent evidence on lifestyle modifications and first or recurrent stroke risk. Recent findings: Weight reduction, low-risk diet, regular physical activity, smoking cessation, and low-to-moderate alcohol consumption may reduce stroke risk up to 50% or more, but level one evidence is still lacking for several interventions. Appropriate food ingredients can significantly decrease stroke risk as recently confirmed for Mediterranean diet. The optimal intensity and amount of physical exercise is still not well established before and after stroke, although modest levels of activity ...
Source: Current Opinion in Neurology - January 12, 2016 Category: Neurology Tags: CEREBROVASCULAR DISEASE: Edited by Patrik Michel Source Type: research

Progranulin and short‐term outcome in patients with acute ischaemic stroke
ConclusionsSerum PGRN levels independently predicted all‐cause mortality and adverse functional outcome in the short term in stroke patients. The discriminative power was improved by PGRN on the basis of NIHSS score.
Source: European Journal of Neurology - January 5, 2016 Category: Neurology Authors: S. Xie, L. Lu, L. Liu, G. Bi, L. Zheng Tags: Original Article Source Type: research

Genetic risk factors for spontaneous intracerebral haemorrhage
Nature Reviews Neurology 12, 40 (2016). doi:10.1038/nrneurol.2015.226 Authors: Amanda M. Carpenter, Inder P. Singh, Chirag D. Gandhi & Charles J. Prestigiacomo Intracerebral haemorrhage (ICH) is associated with the greatest morbidity and mortality of all stroke subtypes. Established risk factors for ICH include hypertension, alcohol use, current cigarette smoking, and use of oral anticoagulants and/or antiplatelet agents. Familial aggregation of ICH has been observed, and the heritability
Source: Nature Reviews Neurology - December 16, 2015 Category: Neurology Authors: Amanda M. CarpenterInder P. SinghChirag D. GandhiCharles J. Prestigiacomo Tags: Review Source Type: research

Moderate alcohol intake reduces risk of ischemic stroke in Korea
Conclusions: Our findings suggest that light to moderate distilled alcohol consumption may reduce the risk of ischemic stroke in Koreans.
Source: Neurology - November 30, 2015 Category: Neurology Authors: Lee, S. J., Cho, Y.-J., Kim, J. G., Ko, Y., Hong, K.-S., Park, J.-M., Kang, K., Park, T. H., Park, S.-S., Lee, K. B., Cha, J. K., Kim, D.-H., Lee, J., Kim, J.-T., Lee, J., Lee, J. S., Jang, M. S., Han, M.-K., Gorelick, P. B., Bae, H.-J., On behalf of the Tags: All Cerebrovascular disease/Stroke, Clinical trials Observational study (Cohort, Case control), Case control studies ARTICLE Source Type: research

The effects of socioeconomic status on stroke risk and outcomes
Publication date: December 2015 Source:The Lancet Neurology, Volume 14, Issue 12 Author(s): Iain J Marshall, Yanzhong Wang, Siobhan Crichton, Christopher McKevitt, Anthony G Rudd, Charles D A Wolfe The latest evidence on socioeconomic status and stroke shows that stroke not only disproportionately affects low-income and middle-income countries, but also socioeconomically deprived populations within high-income countries. These disparities are reflected not only in risk of stroke but also in short-term and long-term outcomes after stroke. Increased average levels of conventional risk factors (eg, hypertension, hyper...
Source: The Lancet Neurology - November 11, 2015 Category: Neurology Source Type: research

Review The effects of socioeconomic status on stroke risk and outcomes
The latest evidence on socioeconomic status and stroke shows that stroke not only disproportionately affects low-income and middle-income countries, but also socioeconomically deprived populations within high-income countries. These disparities are reflected not only in risk of stroke but also in short-term and long-term outcomes after stroke. Increased average levels of conventional risk factors (eg, hypertension, hyperlipidaemia, excessive alcohol intake, smoking, obesity, and sedentary lifestyle) in populations with low socioeconomic status account for about half of these effects.
Source: Lancet Neurology - November 9, 2015 Category: Neurology Authors: Iain J Marshall, Yanzhong Wang, Siobhan Crichton, Christopher McKevitt, Anthony G Rudd, Charles D A Wolfe Tags: Review Source Type: research

IV thrombolysis in patients with ischemic stroke and alcohol abuse
Conclusions: IS patients with chronic alcohol consumption or acute intoxication have decreased likelihood of receiving IVT and are not at an increased risk of associated SICH. This supports current practice guidelines, which do not list chronic alcohol consumption or acute intoxication as an exclusion criterion.
Source: Neurology - November 2, 2015 Category: Neurology Authors: Gattringer, T., Enzinger, C., Fischer, R., Seyfang, L., Niederkorn, K., Khalil, M., Ferrari, J., Lang, W., Brainin, M., Willeit, J., Fazekas, F. Tags: Alcohol, Cohort studies, Infarction ARTICLE Source Type: research

Risk Factors Associated With the Presence of Unruptured Intracranial Aneurysms Clinical Sciences
Conclusions— The risk factors for UIAs differ by their location, compared with the control. Interestingly, the presence of coronary artery disease was protective against the presence of UIAs.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Kang, H. G., Kim, B. J., Lee, J., Kim, M.-J., Kang, D.-W., Kim, J. S., Kwon, S. U. Tags: Cerebral Aneurysm, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage Clinical Sciences Source Type: research

Midlife Alcohol Consumption and the Risk of Stroke in the Atherosclerosis Risk in Communities Study Clinical Sciences
Conclusions— Self-reported light-to-moderate alcohol consumption at midlife was not associated with reduced stroke risk compared with abstention over 20 years of follow-up in the Atherosclerosis Risk in Communities study. Heavier consumption increased the risk for both outcomes as did moderate intake for ICH.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Jones, S. B., Loehr, L., Avery, C. L., Gottesman, R. F., Wruck, L., Shahar, E., Rosamond, W. D. Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Epidemiology Clinical Sciences Source Type: research

Clinical Reasoning: A 58-year-old man with right facial numbness
A 58-year-old man with a history of uncontrolled hypertension presented to the emergency department for evaluation of right facial numbness. He went to bed feeling normal and woke up with numbness and tingling in the right face limited to the right perioral area. He denied any associated neurologic symptoms or having similar experiences in the past. His medical history was significant for uncontrolled hypertension; surgical history was negative. Social history was pertinent for occasional alcohol use, but no smoking or drug use. Family history was significant for hypertension in both parents and essential tremor in his sis...
Source: Neurology - October 19, 2015 Category: Neurology Authors: Egan, K. A., Sevush-Garcy, J. L., Lukovic, E., Sherzai, A. Z., Yaghi, S. Tags: Tremor, All Cerebrovascular disease/Stroke, Infarction RESIDENT AND FELLOW SECTION Source Type: research

Stroke: Alcohol consumption does not seem to protect against stroke
Nature Reviews Neurology 11, 611 (2015). doi:10.1038/nrneurol.2015.181 Author: Hemi Malkki Light-to-moderate drinking in midlife does not protect against stroke, and even moderate doses of alcohol could increase the risk of haemorrhagic stroke, according to a recently published, large self-report study with over 20 years of follow-up. The results contrast with some previous studies and recent
Source: Nature Reviews Neurology - October 13, 2015 Category: Neurology Authors: Hemi Malkki Tags: Research Highlight Source Type: research