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Specialty: Neurology
Condition: Alcoholism

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Total 356 results found since Jan 2013.

Stroke-Specific Predictors of Major Bleeding in Anticoagulated Patients With Stroke and Atrial Fibrillation: A Nationwide Multicenter Registry-Based Study
CONCLUSIONS: This study found that major bleeding risk was independently associated with stroke-specific factors in anticoagulated patients with stroke and AF. This has the clinical implication that baseline characteristics of patients with stroke and AF should be considered in secondary prevention, which would bring the net clinical benefit of balancing recurrent stroke prevention with minimal bleeding complications.PMID:37455504 | DOI:10.3988/jcn.2022.0289
Source: Journal of Clinical Neurology - July 17, 2023 Category: Neurology Authors: Darda Chung Tae-Jin Song Bum Joon Kim Sung Hyuk Heo Jin-Man Jung Kyungmi Oh Chi Kyung Kim Sungwook Yu Kwang Yeol Park Jeong-Min Kim Jong-Ho Park Man-Seok Park Joon-Tae Kim Yang-Ha Hwang Yong-Jae Kim Jong-Won Chung Oh Young Bang Gyeong-Moon Kim Woo-Keun Se Source Type: research

The Study of Risk Factors and The Predict Model of Cerebral Microbleeds
CONCLUSIONS: Hypertension, alcohol use, hemorrhagic stroke history and WMH were added into the model- HPSAD3, and there was a higher possibility of patients with CMBs ≥10 when the score of HPSAD3 ≥4.PMID:37431898 | DOI:10.2174/1567202620666230710160809
Source: Current Neurovascular Research - July 11, 2023 Category: Neurology Authors: Tao Lv Changqing Li Source Type: research

Aspirin and Subarachnoid Haemorrhage in the UK Biobank
In this study, we aimed to clarify the association between aspirin and SAH in the general population. The UK Biobank is a prospective population-based cohort study. Sex, age, smoking, alcohol, medication use, hypertension, blood pressure, ischaemic heart disease and stroke were recorded at baseline assessments. Follow-up is conducted through linkages to National Health Service data including electronic, coded death certificate, hospital and primary care data. Cox proportional hazards modelling was used to analyse the association between aspirin use and SAH. Of the 501,060 participants included in the analysis, a total of 5...
Source: Translational Stroke Research - June 29, 2023 Category: Neurology Source Type: research

Stroke burden and attributable risk factors in China, 1990 –2019
ConclusionThis study reinforced the findings of an increased stroke burden in China. Precise stroke prevention strategies are needed to reduce the disease burden of stroke.
Source: Frontiers in Neurology - May 24, 2023 Category: Neurology Source Type: research

High-mobility group box 1 (HMGB1) crosses the BBB Bidirectionally
Brain Behav Immun. 2023 May 3:S0889-1591(23)00116-2. doi: 10.1016/j.bbi.2023.04.018. Online ahead of print.ABSTRACTHigh-mobility group box 1 (HMGB1) is a ubiquitous protein that regulates transcription in the nucleus, and is an endogenous damage-associated molecular pattern molecule that activates the innate immune system. HMGB1 activates TLR4 and RAGE receptor, inducing downstream signals reminiscent of cytokines, which have been found to cross the blood-brain barrier (BBB). Blood HMGB1 increases in stroke, sepsis, senescence, alcohol binge drinking and other conditions. Here, we examined the ability of HMGB1 radioactivel...
Source: Brain, Behavior, and Immunity - May 5, 2023 Category: Neurology Authors: William A Banks Kim M Hansen Michelle A Erickson Fulton T Crews Source Type: research

Health behavior of young patients with ischemic stroke in Estonia: A score of five factors
ConclusionsBefore stroke, young patients displayed significantly worse health behavior than the general population. The largest differences were found for smoking and obesity, and a cumulation of risk factors was observed via the HBSR score.
Source: Brain and Behavior - February 15, 2023 Category: Neurology Authors: Minni Saapar, Riina Vibo, Siim Schneider, Liisa K õrv, Sandra Mallene, Janika Kõrv Tags: ORIGINAL ARTICLE Source Type: research

The association between HDL ‐C and stroke in the middle‐aged and elderly: A cross‐sectional study
ConclusionWe found a nonlinear relationship between HDL-C and total stroke. Our study reveals a range of inverse associations between HDL-C and stroke (HDL-C<1.55  mmol/L), especially among men and Whites. This finding suggested that maintaining an appropriate HDL-C range may be beneficial in reducing the incidence of stroke.
Source: Brain and Behavior - February 7, 2023 Category: Neurology Authors: Yang Hu, Min Song, Dongmei Wu, Yuqing Zhang, Gongbo Li, Haiyan Luo Tags: ORIGINAL ARTICLE Source Type: research