Age-Specific Cutoff Scores on a T1-Weighted Axial Medial Temporal-Lobe Atrophy Visual Rating Scale in Alzheimer's Disease Using Clinical Research Center for Dementia of South Korea Data.
This study aimed to determine the optimal cutoff score on a T1-weighted axial MTA Visual Rating Scale (VRS) for differentiating patients with AD from cognitively normal elderly people. METHODS: The 3,430 recruited subjects comprising 1,427 with no cognitive impairment (NC) and 2003 AD patients were divided into age ranges of 50-59, 60-69, 70-79, and 80-89 years. Of these, 446 participants (218 in the NC group and 228 in the AD group) were chosen by random sampling for inclusion in this study. Each decade age group included 57 individuals, with the exception of 47 subjects being included in the 80- to 89-year NC group. ...
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Adverse Events During Perampanel Adjunctive Therapy in Intractable Epilepsy.
CONCLUSIONS: Slow titration of perampanel may reduce perampanel-related adverse events. PMID: 29971974 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Clinical Presentations and Phenotypic Spectrum of Multiple Sclerosis at a University Hospital in Saudi Arabia.
CONCLUSIONS: MS presenting in the hospital setting is more common in KSA than reported previously, and the number of diagnosed cases in increasing. It is therefore an emerging and disabling neurological illness in KSA with clinical characteristics not dissimilar to those in other middle eastern countries. A decrease in the frequency of patients with secondary progressive multiple sclerosis (SPMS) indicates either that more new cases of RRMS are being diagnosed or that adequate treatments of RRMS are preventing the evolution to SPMS. Further larger and population-wide epidemiological and clinical studies with the long-term ...
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Effect of Vitamin D Deficiency on the Frequency of Headaches in Migraine.
Authors: Song TJ, Chu MK, Sohn JH, Ahn HY, Lee SH, Cho SJ Abstract BACKGROUND AND PURPOSE: The risk of vitamin D deficiency varies with the season. The frequency of vitamin D deficiency in migraine patients and its association with migraine are unclear. METHODS: We retrospectively evaluated first-visit migraine patients between January 2016 and May 2017, and investigated the demographics, season, migraine subtypes, frequency, severity, and impact of migraine, psychological and sleep variables, climate factors, and vitamin D levels. The nonfasting serum 25-hydroxyvitamin D concentration was measured to determine...
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

The Etiologies of Chronic Progressive Cerebellar Ataxia in a Korean Population.
CONCLUSIONS: This is the largest epidemiological study to analyze the frequencies of various cerebellar ataxias in a Korean population based on the large database of a tertiary hospital movement-disorders clinic in South Korea. These data would be helpful for clinicians in constructing diagnostic strategies and counseling for patients with cerebellar ataxias. PMID: 29971977 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Hand Tremor Questionnaire: A Useful Screening Tool for Differentiating Patients with Hand Tremor between Parkinson's Disease and Essential Tremor.
CONCLUSIONS: The developed Hand Tremor Questionnaire might be a good screening tool for hand tremors in patients with PD and ET. PMID: 29971978 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Clinical Application of 2017 McDonald Diagnostic Criteria for Multiple Sclerosis.
CONCLUSIONS: The new 2017 Multiple Sclerosis criteria may have an important impact in clinical practice with an earlier treatment to avoid the risk of disease dissemination. Their application requires a careful assessment to avoid misdiagnosis and mistreatments. PMID: 29971979 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Postoperative Transient Neurologic Dysfunction: A Proposal for Pathophysiology.
CONCLUSIONS: Transient neurologic dysfunction can occur during the postoperative period of brain surgery. Although this may last more than usual transient ischemic attack or seizure, it eventually resolves regardless of treatment. Based on our observation, we propose that this is the manifestation of the transient cortical depression triggered by mechanical stimulation, analogous to migraine aura associated with cortical spreading depression. PMID: 29971980 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Clinical Heterogeneity of Anti-GM2-Ganglioside-Antibody Syndrome.
CONCLUSIONS: This study has identified that anti-GM2 antibody can be found in various subtypes of GBS and its variants in rare cases. Compared to the clinical heterogeneity of the IgM-positive group, the IgG-positive group can be characterized by cranial-dominant GBS variants presenting mainly with oculomotor and vestibular dysfunctions. PMID: 29971981 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Mechanical Thrombectomy in Strokes with Large-Vessel Occlusion Beyond 6 Hours: A Pooled Analysis of Randomized Trials.
This study performed a pooled analysis of data from trials in which mechanical thrombectomy was performed beyond 6 hours from symptom onset. METHODS: We searched for randomized controlled trials that compared mechanical thrombectomy with the best medical treatment beyond 6 hours for ischemic strokes due to ELVO and reported on between 1990 and April 2018. The intervention group comprised patients treated with mechanical thrombectomy. Statistical analysis was conducted while pooling data and analyzing fixed- or random-effects models as appropriate. RESULTS: Four trials involving 518 stroke patients met the eligibili...
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Alanyl-tRNA Synthetase 2-Related Dementia with Selective Bilateral Frontal Cystic Leukoencephalopathy.
Authors: Carle G, Morin A, Noiray C, Roy-Joly P, Cohen L, Levy R, Samaan S, Nadjar Y PMID: 29971983 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

An Elderly Woman with Reversal of Clinical Presentation Mimicking Rapid-Onset Dystonia-Parkinsonism.
Authors: Ahn BJ, Kwon KY PMID: 29971984 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Near-Fatal Statin-Associated Autoimmune Myositis.
Authors: Vithayathil M, Phung A PMID: 29971985 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Crab Sign in Bilateral Extracranial Vertebral Artery Dissection.
Authors: Peters N, Engelter ST PMID: 29971986 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

The Impact of a National Healthcare System on the Doctor-Patient Relationship in Neurology.
Authors: Park JE PMID: 29971987 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Patterns of Orthostatic Blood Pressure Changes in Patients with Orthostatic Hypotension.
The objective of this study was to determine the patterns of blood pressure (BP) changes during the head-up tilt (HUT) test, particularly in terms of its clinical significance for patients with orthostatic hypotension (OH). METHODS: OH was divided into four categories based on systolic BP changes occurring within the first 10 minutes of the HUT test: sustained orthostatic hypotension (SOH), progressive orthostatic hypotension (POH), orthostatic hypotension with partial recovery (OHPR), and transient orthostatic hypotension (TOH). RESULTS: In total, 151 patients were analyzed: 65 with SOH, 38 with POH, 21 with OHPR,...
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Severe Hemifacial Spasm is a Predictor of Severe Indentation and Facial Palsy after Microdecompression Surgery.
CONCLUSIONS: Spasm severity does not predict surgical outcomes, but it can be used as a marker of pathologic compression in MVD for HFS, and be considered as a predictor of delayed facial palsy after MVD. PMID: 29856152 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Stimulation in Supplementary Motor Area Versus Motor Cortex for Freezing of Gait in Parkinson's Disease.
Authors: Kim SJ, Paeng SH, Kang SY Abstract BACKGROUND AND PURPOSE: Freezing of gait (FOG) is a frustrating problem in Parkinson's disease (PD) for which there is no effective treatment. Our aim was to find brain stimulation areas showing greater responses for reducing FOG. METHODS: Twelve PD patients with FOG were selected for inclusion. We explored the therapeutic effect of repetitive transcranial magnetic stimulation (rTMS) in the supplementary motor area (SMA) and the motor cortex (MC). We measured the number of steps, completion time, and freezing episodes during the stand-walk-sit test before and after rT...
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Sympathetic Overactivity Based on Heart-Rate Variability in Patients with Obstructive Sleep Apnea and Cerebral Small-Vessel Disease.
CONCLUSIONS: Our findings suggest that dysregulation of HRV, especially overactivation of sympathetic tone, could be a pathophysiologic mechanism underlying the development of WMC in OSA patients. PMID: 29856154 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial.
CONCLUSIONS: This study shows that treatment with unpolished-rice-germ-derived GABA improved not only the subjective sleep quality but also the objective sleep efficacy without severe adverse events. PMID: 29856155 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Secondary Short-Lasting Unilateral Neuralgiform Headache with Conjunctival Injection and Tearing: A New Case and a Literature Review.
In conclusion, the neurobiology of secondary SUNCT includes structures such as the nucleus and the trigeminal nerve with its branches, suggesting that some cases of primary SUNCT have underlying mechanisms that are related to existing focal damage that cannot be visualized. PMID: 29856156 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Interleukin-6, S-Nitrosothiols, and Neurodegeneration in Different Central Nervous System Demyelinating Disorders: Is There a Relationship?
CONCLUSIONS: These results confirm that IL-6 is activated in different demyelinating disorders, with this elevation being more prominent in the CSF of NMOSD with AQP4-IgG and ADEM patients. Moreover, S-nitrosylation is activated in demyelinating disorders with spinal-cord injury and neurodegeneration in these patients. However, we found no correlation between these biochemical markers, and so we could not confirm whether IL-6-mediated nitric oxide production is involved in spinal-cord lesions. PMID: 29856157 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Efficacy of Gaze Photographs in Diagnosing Ocular Myasthenia Gravis.
Authors: Ahn J, Park KS, Kim JS, Hwang JM Abstract BACKGROUND AND PURPOSE: The various tests that are routinely used to diagnose generalized myasthenia gravis, such as the edrophonium test, serum anti-acetylcholine-receptor antibodies (AChR-Ab), and repetitive nerve stimulation (RNS) tests, have lower diagnostic sensitivity in ocular myasthenia gravis (OMG). Diagnosing OMG becomes even more difficult when the clinical symptoms are subtle. There is no gold-standard diagnostic test available for OMG patients, and so this study compared the diagnostic sensitivity of gaze photographs with conventional tests in OMG. ...
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Recurrent Optic Neuritis as the Initial Symptom in Demyelinating Diseases.
CONCLUSIONS: A lower VFSS at the last medical appointment was predictive of MS. Patients with NMOSD and CRION have similar clinical characteristics, whereas NMOSD patients tend to have worse visual acuity. PMID: 29856159 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Applicability of McDonald 2010 and Magnetic Resonance Imaging in Multiple Sclerosis (MAGNIMS) 2016 Magnetic Resonance Imaging Criteria for the Diagnosis of Multiple Sclerosis in Sri Lanka.
CONCLUSIONS: MAGNIMS 2016 MRI criteria were superior to McDonald 2010 MRI criteria in specificity, accuracy, and PPV, but inferior in sensitivity and NPV. PMID: 29856160 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Incidence and Clinical Significance of Positional Downbeat Nystagmus in Posterior Canal Benign Paroxysmal Positional Vertigo.
CONCLUSIONS: Our study found transient pDBN in 40% of patients with PC BPPV after the immediate resolution of positional vertigo and pT-UBN. pDBN may be attributed to residual debris in the distal portion of the PC, which can move toward the ampulla producing an ampullopetal flow of endolymph during positioning. PMID: 29856161 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Measurement of the Optic Nerve Sheath Diameter with Magnetic Resonance Imaging and Its Association with Eyeball Diameter in Healthy Adults.
Authors: Kim DH, Jun JS, Kim R Abstract BACKGROUND AND PURPOSE: The optic nerve sheath diameter (ONSD) is an indirect marker of the intracranial pressure, but the normal range of ONSD as measured using magnetic resonance imaging (MRI) and its associations with clinical parameters and the eyeball transverse diameter (ETD) remain unclear. METHODS: We included 314 healthy adults who underwent brain MRI examinations for health screening between June 2014 and September 2017. The ONSD and ETD of each eye were calculated using time-of-flight magnetic resonance angiography. Linear regression analyses were performed to ...
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

A Psychiatric Side Effect of Levetiracetam Can Mimic a Relapse of Anti-Leucine-Rich Glioma Inactivated 1 Encephalitis.
Authors: Jang Y, Lee ST, Chu K, Lee SK PMID: 29856163 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Ultrasonography in the Early Diagnosis of Diabetic Lumbosacral Radiculoplexus Neuropathy.
Authors: An JY, Bae DW, Walker FO PMID: 29856164 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Agenesis of the Internal Carotid Artery Associated with Generalized Epilepsy.
Authors: La Spina P, Grillo F, Granata F, Casella C, Fazio MC, Colella M, Cotroneo M, Dell'Aera C, Ciacciarelli A, Vita G, Musolino R PMID: 29856165 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Hematoma-Related Nonhabitual Seizures during Subdural Electrode Monitoring.
Authors: Hwang KJ, Joo EY, Hong SB, Seo DW PMID: 29856166 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

The Influence of Sex in Stroke Thrombolysis: A Systematic Review and Meta-Analysis.
Authors: Liu M, Li G, Tang J, Liao Y, Li L, Zheng Y, Guo T, Kang X, Yuan M Abstract BACKGROUND AND PURPOSE: There is increasing recognition of the importance of stroke in females to both clinical and public health. The natural course of stroke is worse in females than in males, but the evidence regarding sex disparities in the responses to thrombolysis in stroke patents is still controversial. We compared outcomes after thrombolysis treatment between females and males. METHODS: Clinical trials reported in the Embase, PubMed, and Cochrane Library electronic databases up to March 13, 2017 were included in this an...
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Attention Deficit Hyperactivity Disorder in Neurofibromatosis Type 1: Evaluation with a Continuous Performance Test.
The objective of this study was to determine if the MOXO visual- and vocal-distractors-based continuous performance test distinguishes patients with attention deficit hyperactivity disorder (ADHD) and neurofibromatosis type 1 (NF1) from those without NF1. METHODS: Thirty-five patients (16 males; mean age 9.91 years) attending a multidisciplinary NF1 clinic completed the MOXO test. The findings were compared to 532 healthy age-matched standardized control subjects (285 males) without ADHD. RESULTS: The overall performance in the MOXO text was significantly worse in the NF1 group than in controls (p
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Glucose Hypometabolism in Hippocampal Subdivisions in Alzheimer's Disease: A Pilot Study Using High-Resolution ¹⁸F-FDG PET and 7.0-T MRI.
CONCLUSIONS: It was possible to use high-resolution PET-MRI fusion images to identify hippocampus subdivisions and assess glucose metabolism in the subfields. Reductions in metabolic activity were found to vary along the hippocampal axis in early-stage AD patients. PMID: 29629524 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

High Dietary Glycemic Load is Associated with Poor Functional Outcome in Patients with Acute Cerebral Infarction.
CONCLUSIONS: Increased dietary GL and carbohydrate intake were associated with a poor short-term functional outcome after an acute ischemic stroke. PMID: 29629525 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Underregistration and Underreporting of Stem Cell Clinical Trials in Neurological Disorders.
CONCLUSIONS: Many registered SC trials related to neurological disorders are not reported, while many SC-related publications are not registered in a public registry. These results support the presence of biased reporting and publication bias in SC trials related to neurological disorders in Korea. PMID: 29629526 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

An 8-Week Low-Intensity Progressive Cycling Training Improves Motor Functions in Patients with Early-Stage Parkinson's Disease.
Authors: Chang HC, Lu CS, Chiou WD, Chen CC, Weng YH, Chang YJ Abstract BACKGROUND AND PURPOSE: The effects of high-intensity cycling as an adjuvant therapy for early-stage Parkinson's disease (PD) were highlighted recently. However, patients experience difficulties in maintaining these cycling training programs. The present study investigated the efficacy of cycling at a mild-to-moderate intensity in early-stage PD. METHODS: Thirteen PD patients were enrolled for 16 serial cycling sessions over a 2-month period. Motor function was assessed using the Unified Parkinson's Disease Rating Scale part III (UPDRS III)...
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Prevalence of Multiple Sclerosis in a Turkish City Bordering an Iron and Steel Factory.
CONCLUSIONS: We found that the prevalence of MS was more than two fold higher in Karabük than in Akçakoca, which supports a link between air pollution and the pathogenesis of MS. However, larger etiological and epidemiological studies are needed to confirm this hypothesis. PMID: 29629528 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Questioning the Diagnosis of Recurrent Optic Neuritis Associated with Neuro-Beh çet's Disease.
Questioning the Diagnosis of Recurrent Optic Neuritis Associated with Neuro-Behçet's Disease. J Clin Neurol. 2018 Apr;14(2):242-243 Authors: Bae SY, Kim YW, Shin KJ PMID: 29629529 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Paraneoplastic Neuromyelitis Optica Associated with Lung Adenocarcinoma in a Young Woman.
Authors: Baik KW, Kim SH, Shin HY PMID: 29629530 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Pathogenic Variant of REEP1 in a Korean Family with Autosomal-Dominant Hereditary Spastic Paraplegia.
Authors: Park HJ, Lee MJ, Lee JE, Park KD, Choi YC PMID: 29629531 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Self-Injurious Behavior Revealing Advanced Primary Progressive Multiple Sclerosis with a Massive Right Temporal Lesion.
Authors: Gschwind M, Lascano AM, Kaya G, Assal F PMID: 29629532 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Central Trochlear Palsy as an Isolated Finding with Metastatic Tumor.
Authors: Lee SU, Choi JY, Kim HJ, Kim JS PMID: 29629533 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Multiple Cranial-Nerve Palsies: An Unusual Culprit.
Authors: Shashikala TP, Mehta S, Sharma A, Rai Mittal B PMID: 29629534 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Is Corticospinal Tract Degeneration Caused by Sj ögren Syndrome?
Is Corticospinal Tract Degeneration Caused by Sjögren Syndrome? J Clin Neurol. 2018 Apr;14(2):259-260 Authors: Nam TS, Levy M, Kim SH, Kang KW, Kim BJ, Lee SH PMID: 29629535 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Coexistence of Amyotrophic Lateral Sclerosis in the Proband of an X-Linked Charcot-Marie-Tooth Disease Type 1 Pedigree in China.
Authors: Feng SY, Feng SM, Li LY, Zou ZY PMID: 29629536 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Different Associations of Plasma Biomarkers in Alzheimer's Disease, Mild Cognitive Impairment, Vascular Dementia, and Ischemic Stroke.
CONCLUSIONS: This is the first report of differences in the expression levels of plasma biomarkers and peripheral arterial tonometry among AD, MCI, VaD, and IS patients and normal controls. These different associations indicate that diverse pathological mechanisms underlie these diseases. PMID: 29629537 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Changes in the Common Carotid Artery after Radiotherapy: Wall Thickness, Calcification, and Atherosclerosis.
Authors: Kim BJ, Kang HG, Lee SW, Jung J, Lee MH, Kang DW, Kim JS, Kwon SU Abstract BACKGROUND AND PURPOSE: Since the long-term survival rate has improved in laryngeal cancer patients who receive radiotherapy, concerns about postradiation complications (including carotid atherosclerosis) have increased. We followed changes in the common carotid artery (CCA) after radiotherapy and identified the underlying risk factors. METHODS: Consecutive patients with laryngeal cancer who underwent radiotherapy between January 1999 and December 2009 and who had received computed tomography (CT) both pre- and postradiotherapy ...
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Prevalence, Incidence, and Recurrence of Febrile Seizures in Korean Children Based on National Registry Data.
CONCLUSIONS: Our study determined the overall prevalence of FS using data for the total population in Korea. The prevalence was comparable to that reported for other countries. Patients with three episodes of FS need to be monitored carefully. PMID: 29629539 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Role of Language-Related Functional Connectivity in Patients with Benign Childhood Epilepsy with Centrotemporal Spikes.
Authors: Kim HJ, Lee JH, Park CH, Hong HS, Choi YS, Yoo JH, Lee HW Abstract BACKGROUND AND PURPOSE: Benign childhood epilepsy with centrotemporal spikes (BECTS) does not always have a benign cognitive outcome. We investigated the relationship between cognitive performance and altered functional connectivity (FC) in the resting-state brain networks of BECTS patients. METHODS: We studied 42 subjects, comprising 19 BECTS patients and 23 healthy controls. Cognitive performance was assessed using the Korean version of the Wechsler Intelligence Scale for Children-III, in addition to verbal and visuospatial memory tes...
Source: Journal of Clinical Neurology - April 10, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research