Clinical Approach to Autoimmune Epilepsy.
Authors: Jang Y, Kim DW, Yang KI, Byun JI, Seo JG, No YJ, Kang KW, Kim D, Kim KT, Cho YW, Lee ST, Drug Committee of Korean Epilepsy Society Abstract Autoimmune epilepsy is a newly emerging area of epilepsy. The concept of "autoimmune" as an etiology has recently been revisited thanks to advances in autoimmune encephalitis and precision medicine with immunotherapies. Autoimmune epilepsy presents with specific clinical manifestations, and various diagnostic approaches including cerebrospinal fluid analysis, neuroimaging, and autoantibody tests are essential for its differential diagnosis. The diagnosis is o...
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Anti-SOX1 Antibodies in Paraneoplastic Neurological Syndrome.
In conclusion, the presence of anti-SOX1 abs alone is a potential predictor of an uncommon paraneoplastic neurological disorder, usually occurring in the setting of LEMS, PCD, and SCLC. The detection of anti-SOX1 abs contributes to an early diagnosis of underlying tumors, given the diversity of clinical symptoms and the absence of characteristic neuroimaging features. PMID: 33029958 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Antiepileptic Drug Selection According to Seizure Type in Adult Patients with Epilepsy.
Authors: Kim H, Kim DW, Lee ST, Byun JI, Seo JG, No YJ, Kang KW, Kim D, Kim KT, Cho YW, Yang KI, Drug Committee of Korean Epilepsy Society Abstract Epilepsy is a common neurological disorder that is mainly treated using antiepileptic drugs. Several antiepileptic drugs such as phenobarbital, phenytoin, primidone, and ethosuximide were developed in the early 20th century. More than 10 types of antiepileptic drugs have been developed since the 1990s, and there are now more than 20 antiepileptic drugs in active clinical use. The choice of antiepileptic drugs is based on the clinical features of the seizure types, elect...
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Pharmacological Treatment of Epilepsy in Elderly Patients.
Authors: Seo JG, Cho YW, Kim KT, Kim DW, Yang KI, Lee ST, Byun JI, No YJ, Kang KW, Kim D, Drug Committee of Korean Epilepsy Society Abstract The incidence and prevalence of epilepsy are highest in elderly people, and the etiologies of epilepsy in the elderly differ from those in other age groups. Moreover, diagnosing and treating epilepsy in elderly people may be challenging due to differences in clinical characteristics and physiological changes associated with aging. This review focuses on the pharmacological treatment of epilepsy in elderly patients. PMID: 33029960 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Paramagnetic Rims in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder: A Quantitative Susceptibility Mapping Study with 3-T MRI.
CONCLUSIONS: Paramagnetic rims might be a characteristic MRI finding for MS, and therefore they have potential as an imaging marker for differentially diagnosing MS from NMOSD using 3-T MRI. PMID: 33029961 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Altered Structural Network in Newly Onset Childhood Absence Epilepsy.
Authors: Kim EH, Shim WH, Lee JS, Yoon HM, Ko TS, Yum MS Abstract BACKGROUND AND PURPOSE: Recent quantitative neuroimaging studies of childhood absence epilepsy (CAE) have identified various structural abnormalities that might be involved in the onset of absence seizure and associated cognitive and behavioral functions. However, the neuroanatomical alterations specific to CAE remain unclear, and so this study investigated the regional alterations of brain structures associated with newly diagnosed CAE. METHODS: Surface and volumetric magnetic resonance imaging data of patients with newly diagnosed CAE (n=18) an...
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

High Cell-Free DNA Levels in Cerebrospinal Fluid Predict Leptomeningeal Seeding of Hematologic Malignancy.
CONCLUSIONS: The cfDNA level in the CSF can be used as a supplemental marker for diagnosing LMS in hematologic malignancy patients. PMID: 33029963 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Reliability and Validity of the Korean Version of the Spinal and Bulbar Muscular Atrophy Functional Rating Scale.
CONCLUSIONS: We have performed a validation study of the Korean version of a disease-specific functional rating scale for SBMA patients. The SBMAFRS is a useful tool for clinical practice and as a potential outcome measure for Korean SBMA patients. PMID: 33029964 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Shape Analysis of the Subcortical Nuclei in Amyotrophic Lateral Sclerosis without Cognitive Impairment.
CONCLUSIONS: Subcortical gray-matter structures are involved in the neurodegenerative process of ALS before cognitive impairment becomes evident. PMID: 33029965 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Transient Homonymous Superior Quadrantanopsia in Nonketotic Hyperglycemia: A Case Report and Systematic Review.
CONCLUSIONS: Nonketotic hyperglycemia should be considered a possible cause of transient visual field defects, especially when it is associated with repetitive positive visual symptoms and typical MRI findings in hyperglycemic patients. PMID: 33029966 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Causes, Risk Factors, and Clinical Outcomes of Stroke in Korean Young Adults: Systemic Lupus Erythematosus is Associated with Unfavorable Outcomes.
CONCLUSIONS: Young adult IS patients in Korea exhibit low awareness and poor management of their risk factors. Although the short-term outcome was relatively favorable in those patients, having SLE was associated with unfavorable outcomes. More attention needs to be paid for improving awareness and controlling risk factors in this population. PMID: 33029967 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Effects of Multicomponent Exercise on Cognitive Function in Elderly Korean Individuals.
CONCLUSIONS: Individually customized, multicomponent exercise programs lead to improved levels of cognitive function, depression, and quality of life, especially among those who are more frail. PMID: 33029968 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Clinical Features and Outcomes of Intracranial Aneurysm Associated with Moyamoya Disease.
CONCLUSIONS: MMD-associated aneurysms occurred in 3.3% of the MMD cohort in this study, of which 63.6% were major-artery aneurysms and 36.4% were non-major-artery aneurysms. The major-artery group included 17.9% that became angiographically worse, while 31.2% were growing or hemorrhaging in the non-major-artery group. PMID: 33029969 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Validation Study of the Official Korean Version of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale.
CONCLUSIONS: The Korean MDS-UPDRS has the same overall structure as the English MDS-UPDRS. Our translated scale can be designated as the official Korean MDS-UPDRS. PMID: 33029970 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Neuro-ophthalmologic Findings in Visual Snow Syndrome.
CONCLUSIONS: Neuro-ophthalmologic findings are mostly normal in patients with visual snow syndrome. Retinal or neurological diseases must be excluded as possible causes of visual snow. PMID: 33029971 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Clinical Significance of MRI Contrast Enhancement of the Oculomotor Nerve in Ischemic Isolated Oculomotor Nerve Palsy.
CONCLUSIONS: More than half of the iIONP patients had an enhanced oculomotor nerve in MRI. A few of them also had elevated CSF IgG synthesis rate, but no further evidence for inflammation was found. The administration of steroids seemed to have no benefit other than increasing the blood glucose level. PMID: 33029972 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Efficacy of a Second Brain Biopsy for Intracranial Lesions after Initial Negativity.
This study was designed to 1) assess the efficacy of a second brain biopsy when the first biopsy was nondiagnostic, 2) identify possible factors associated with an increased diagnostic rate in the second biopsy, and 3) analyze additional morbidity induced by the second biopsy. METHODS: We performed a retrospective cohort study from 2009 to 2019, during which 1,919 patients underwent a brain biopsy, including 30 who were biopsied twice (1.6%). The specific histological diagnosis rate, diagnosis-associated factors, and complication rate were assessed for the 30 twice-biopsied patients. RESULTS: The second biopsy allo...
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Factors Affecting the Time Taken to Determine Brain Death in Patients with Impending Brain Death.
CONCLUSIONS: The SMs in PWIBDs and a craniotomy performed immediately before starting the process of determining brain death seem to be related to lengthening the TT-BD. PMID: 33029974 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Tacrolimus for Treating Orbital and Cranial Form of Idiopathic Inflammatory Pseudotumors.
CONCLUSIONS: Tacrolimus may be a safe and effective immunosuppressant for refractory or relapsing form of orbital or cranial IIPs. PMID: 33029975 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Impact of Neurointensivist Co-Management in a Semiclosed Neurocritical-Care Unit.
CONCLUSIONS: Despite the higher severity of the condition during neurointensivist co-management, co-management significantly improved clinical outcomes (including the mortality rate) in neurocritical patients. PMID: 33029976 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Central Nervous System Infection-Related Isolated Hippocampal Atrophy as Another Subtype of Medial Temporal Lobe Epilepsy with Hippocampal Atrophy: A Comparison to Conventional Medial Temporal Lobe Epilepsy with Hippocampal Atrophy.
CONCLUSIONS: In addition to bilateral HA, CNS infection alone was not a poor prognostic factor for the CNS infection-related epilepsy with HA group compared with the conventional MTLE with HA group. Based on these negative results, HA is a plausible and relevant lesion with similar clinical characteristics to HA in patients with conventional MTLE. Therefore, CNS infection-related MTLE with isolated HA might represent another subtype of MTLE with HA with a different etiology. PMID: 33029977 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Ultra-Early Remote Intracranial Hemorrhage Complicating Intravenous Thrombolysis with Tenecteplase for Acute Ischemic Stroke.
Authors: Kargiotis O, Safouris A, Psychogios K, Chondrogianni M, Andrikopoulou A, Theodorou A, Magoufis G, Stamboulis E, Tsivgoulis G PMID: 33029978 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Anti-CASPR2-Antibody-Positive Isaacs' Syndrome Presenting with Myokymia, Neuropathic Pain, and Hyperhidrosis.
Authors: Kim H, Lim YM, Lee EJ, Kim HW, Ahn HS, Kim KK PMID: 33029979 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

A Case of Polyneuritis Cranialis with the Initial Symptom of Isolated Hypoglossal Nerve Palsy.
Authors: Ju H, Im K, Roh H PMID: 33029980 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Ultrasonography Findings in Hereditary Neuropathy with Liability to Pressure Palsies Due to Single-Nucleotide Substitution.
Authors: Kim YK, Ro S, Jeong YH, Ann S, Park HJ, Suh BC PMID: 33029981 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Stroke in a Feverish Patient with COVID-19 Infection and Unknown Endocarditis.
Authors: Mantero V, Rigamonti A, Basilico P, Sangalli D, Scaccabarozzi C, Salmaggi A PMID: 33029982 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

First Case of TARDBP-Related Amyotrophic Lateral Sclerosis in Korea.
Authors: Han HJ, Park HJ, Yun U, Choi YC PMID: 33029983 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Inferior Divisional Oculomotor Nerve Palsy Due to Orbital Lymphoma.
Authors: Lee JY, Kim HJ, Kwon E, Choi JY, Oh HJ, Kim JS PMID: 33029984 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Acetylcholine Receptor-Antibody-Positive Myasthenia Gravis Presenting with Early Atrophy and Nonfluctuating Weakness of Proximal Limb Muscles.
Authors: Pancheri E, Bertolasi L, Tonin P, Vattemi G PMID: 33029985 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

A Case of Myositis Preceding Neuropathy in Eosinophilic Granulomatosis with Polyangiitis.
Authors: Woo K, Park YE, Jeon D, Shin JH PMID: 33029986 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Adult-Onset Neuronal Intranuclear Inclusion Disease: First Korean Case Confirmed by Skin Biopsy.
Authors: Chun MY, Park HK, Kim GH, Lee SA, Kim SH, Sung SH, Park YW, Jeong JH PMID: 33029987 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Successful Experience of Cyclic Progesterone Supplementation in Catamenial Epilepsy.
Authors: Kim JS, Hong SH, Kim WS PMID: 33029988 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Chemoradiotherapy Alters Protein Expression in Glioblastoma Multiforme.
Authors: Hwang M, Park HH, Han MH, Choi H, Lee KY, Lee YJ, Kim JM, Cheong JH, Ryu JI, Ko Y, Koh SH PMID: 33029989 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Facial-Onset Sensory Motor Neuronopathy Syndrome is not Always Facial Onset.
Authors: Zhang W, Huang Q, Xuan Z, Wu S, Zhao Y, Xu H PMID: 33029990 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - October 10, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Monoclonal Antibody Therapies for Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder.
This article reviews the use of mAbs for treating MS and NMOSD, including summarizing their mechanisms of action, efficacy, and safety profiles. PMID: 32657055 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Tuberculous Myelopathy Associated with Longitudinally Extensive Lesion: A Clinicoradiological Review of Reported Cases.
Authors: Md Noh MSF, Bahari N, Abdul Rashid AM Abstract Acute transverse myelitis is an inflammatory disorder of the spinal cord in which there is no evidence of spinal cord compression. Longitudinally extensive transverse myelitis (LETM) is a specific subtype of acute transverse myelitis that usually affects three or more vertebral levels and produces marked neurological deficits. While the most-common cause of LETM is neuromyelitis optica or neuromyelitis optica spectrum disorder, there are rare cases of other causes mimicking this condition, including tuberculosis (TB). We sought to review the clinicoradiologica...
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Acute Flaccid Myelitis: Current Status and Diagnostic Challenges.
This article provides a concise overview of our current understanding of AFM and the clinical features that distinguish AFM from AFP and similar other neurological infectious and autoimmune diseases or disorders. We also discuss the diagnosis, clinical pathology, possible pathogenetic mechanisms, and currently available therapies. PMID: 32657057 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Refining General Principles of Antiepileptic Drug Treatments for Epilepsy.
This article is the first in a series on AED treatments for epilepsy in South Korea. PMID: 32657058 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Alterations in Structural and Functional Connectivities in Patients with End-Stage Renal Disease.
CONCLUSIONS: We found that ESRD patients exhibited decreased structural and functional brain connectivities, and that there was a significant association between brain connectivity and cognitive function. These alterations in the brain network may contribute to the pathophysiological mechanism of CI in ESRD patients. PMID: 32657059 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Effects of Evening Exposure to Light from Organic Light-Emitting Diodes on Melatonin and Sleep.
Authors: Park HR, Choi SJ, Jo H, Cho JW, Joo EY Abstract BACKGROUND AND PURPOSE: Organic light-emitting diodes (OLEDs) emit less blue light than traditional light-emitting diodes (LEDs), but the effects of OLED light exposure (LE) on melatonin and sleep have not been evaluated. METHODS: Twenty-four healthy subjects (age 26.9±5.7 years; including 18 females) with the intermediate chronotype were exposed to three different light conditions [4,000 K 150 lux OLED LE, 4,000 K 150 lux LED LE, and dim light (DL) at
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Cefepime-Induced Encephalopathy in a Tertiary Medical Center in Korea.
This study collected demographic data, laboratory findings, and clinical data including the cause of infection, duration for onset of altered consciousness, duration of cefepime treatment, dosage of cefepime, duration of recovering consciousness after stopping cefepime, sequelae after encephalopathy, and electroencephalography data. RESULTS: Forty-four (2.5%) patients were included in the CIE group. The age was significantly higher in the CIE group than in the control group (71.2±10.8 years vs. 64.7±16.1 years, mean±standard deviation; p=0.007), and females constituted a significantly large proport...
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Impact of Puberty in Pediatric Migraine: A Pilot Prospective Study.
CONCLUSIONS: Prodromal symptoms increase in pediatric migraine after 2 years, and some trigger factors for migraine become more prevalent, including sleep disturbances. New accompanying symptoms are also identified. These changes provide information about how migraine changes during puberty along with physical and lifestyle changes, and represent a dynamic physiopathological process that deserves more research. PMID: 32657062 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Correlates of Stigma in People with Epilepsy.
CONCLUSIONS: Stigma burden can be substantial among PLWE and may vary depending on contextual factors such as mental health comorbidity. Care approaches that screen for psychiatric comorbidities, address low health literacy, institute promising self-management programs, and employ effective health communication strategies about epilepsy misconceptions, may reduce epilepsy related burden. PMID: 32657063 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Acute Healthcare Utilization of a Multidisciplinary Neurocognitive Dementia Patient Cohort.
CONCLUSIONS: Performing follow-up in multidisciplinary clinics provides patients with more education and may help to reduce the utilization of healthcare services. PMID: 32657064 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Analysis of Risk Factors for a Poor Prognosis in Patients with Anti-N-Methyl-D-Aspartate Receptor Encephalitis and Construction of a Prognostic Composite Score.
CONCLUSIONS: Age, disturbance of consciousness at admission, and ≥50% slow waves on the EEG were independent risk factors for a poor prognosis. The ACS prognostic composite score could play a role in facilitating early predictions of the prognosis of anti-NMDAR encephalitis. PMID: 32657065 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Heart-Rate-Based Machine-Learning Algorithms for Screening Orthostatic Hypotension.
CONCLUSIONS: We have identified clinical parameters that are strongly associated with OH. Machine-learning analysis using those parameters was highly accurate in differentiating OH from non-OH patients. These parameters could be useful screening factors for OH in patients who are unable to perform the HUTT. PMID: 32657066 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Smoking Cessation, Weight Change, and Risk of Parkinson's Disease: Analysis of National Cohort Data.
CONCLUSIONS: Postcessation weight gain in males did not offset the protective impact of smoking on PD development, although overall weight gain predicted an increased risk of PD. PMID: 32657067 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Clinical Spectrum of Myelin Oligodendrocyte Glycoprotein-Immunoglobulin G-Associated Disease in Korean Children.
CONCLUSIONS: MOG antibodies were identified in all pediatric ADS phenotypes except for monophasic TM. Therefore, the MOG antibody test is recommended for all pediatric patients with ADS, especially before a diagnosis of MS and for patients without a clear diagnosis. PMID: 32657068 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Identification of Medium-Length Antineurofilament Autoantibodies in Patients with Anti-N-Methyl-D-Aspartate Receptor Encephalitis.
CONCLUSIONS: Anti-NFM autoantibodies may be present in patients with anti-NMDAR encephalitis, indicating underlying neuronal damage. A large cohort study is warranted to investigate the clinical differences between patients with NMDAR encephalitis according to their anti-NFM antibody status. PMID: 32657069 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research

Determination of Brain Death/Death by Neurologic Criteria in Countries in Asia and the Pacific.
CONCLUSIONS: The protocols for conducting a BD/DNC determination vary markedly among countries in Asia and the Pacific. Since it is optimal to have internationally and intranationally consistent BD/DNC protocols, efforts should be made to harmonize protocols both within this region and worldwide. PMID: 32657070 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 15, 2020 Category: Neurology Tags: J Clin Neurol Source Type: research