Abnormal Oculomotor Functions in Amyotrophic Lateral Sclerosis.
Authors: Kang BH, Kim JI, Lim YM, Kim KK Abstract BACKGROUND AND PURPOSE: Although traditionally regarded as spared, a range of oculomotor dysfunction has been recognized in amyotrophic lateral sclerosis (ALS) patients. ALS is nowadays considered as a neurodegenerative disorder of a third compartment comprising widespread areas of extra-motor brain including cerebellum. Our objective was to perform an observational study to examine for ocular motor dysfunction in patients with ALS and for any differences between bulbar-onset and spinal-onset patients. METHODS: Thirty two ALS patients (bulbar onset: 10, spinal o...
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Region-Based Analysis of Prevalence and Incidence of Parkinson's Disease: Analysis of the National Sample Cohort in South Korea.
CONCLUSIONS: The standardized prevalence of PD increased steadily from 2003 to 2012 in South Korea, while its standardized incidence has remained constant. There were regional differences in the prevalence and incidence of PD based on the degree of urbanization and the area of agricultural land. PMID: 30198219 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Multimodal Assessment of Neural Substrates in Computerized Cognitive Training: A Preliminary Study.
CONCLUSIONS: The anterior cingulate and anterior insula, which are parts of the salience network, may be substrates for the improvements in cognitive function induced by computerized cognitive training. PMID: 30198220 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Paroxysmal Dyskinesia in Children: from Genes to the Clinic.
CONCLUSIONS: This study has summarized the clinical and genetic heterogeneity of paroxysmal dyskinesia in children. We suggest that pediatric paroxysmal dyskinesia should not be diagnosed using clinical features alone, but by combining them with broader genetic testing. PMID: 30198221 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Consolidation of a Learned Skill Correlates with Dopamine SPECT Uptake in Early Parkinson's Disease.
CONCLUSIONS: This study provides evidence of a correlation between procedural memory impairment and striatal dopaminergic dysfunction in early PD. PMID: 30198222 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

A Novel Homozygous Variant of SETX Causes Ataxia with Oculomotor Apraxia Type 2.
CONCLUSIONS: This report extends the allelic heterogeneity of SETX mutations causing AOA2 and also presents an asymptomatic patient with a pathogenic ATM variant. PMID: 30198223 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Changes in the Multiple Sclerosis Treatment Paradigm. What Do We Do Now and What Were We Doing Before?
CONCLUSIONS: We have identified that the tendency for treatment changes has increased following the arrival of new drugs. Efficacy has been the main cause of these changes. PMID: 30198224 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

The Role of Information Processing Speed in Clinical and Social Support Variables of Patients with Multiple Sclerosis.
Authors: Eizaguirre MB, Vanotti S, Merino Á, Yastremiz C, Silva B, Alonso R, Garcea O Abstract BACKGROUND AND PURPOSE: Information processing speed is one of the most impaired cognitive functions in multiple sclerosis (MS). There are two tests widely used for evaluating information processing speed: the Symbol Digit Modalities Test (SDMT) and the Paced Auditory Serial Addition Test (PASAT). To analyze the relationship between processing speed and the clinical and social support variables of patients with MS. METHODS: A group of 47 patients with relapsing-remitting MS was studied, 31 were women and 16, me...
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Therapeutic Interventions in Adult Low-Grade Gliomas.
Authors: Chammas M, Saadeh F, Maaliki M, Assi H Abstract Treating adult low-grade gliomas (LGGs) is particularly challenging due to the highly infiltrative nature of this type of brain cancer. Although surgery, radiotherapy, and chemotherapy are the mainstay treatment modalities for LGGs, the optimal combination management plan for a particular patient based on individual symptoms and the risk of treatment-induced toxicity remains unclear. This review highlights the competency and limitations of standard treatment options while providing an essential therapeutic update regarding current clinical trials aimed at imp...
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Neuromonitoring for Spinal Cord Stimulation Lead Placement Under General Anesthesia.
Authors: Shils JL, Arle JE Abstract Spinal cord stimulation (SCS) is a common therapeutic technique for treating medically refractory neuropathic back and other limb pain syndromes. SCS has historically been performed using a sedative anesthetic technique where the patient is awakened at various times during a surgical procedure to evaluate the location of the stimulator lead. This technique has potential complications, and thus other methods that allow the use of a general anesthetic have been developed. There are two primary methods for placing leads under general anesthesia, based on 1) compound muscle action po...
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Association between Frontal-Executive Dysfunction and Speech-in-Noise Perception Deficits in Mild Cognitive Impairment.
CONCLUSIONS: Our findings suggest that frontal-executive function is strongly related to speech-in-noise perception and that MCI patients with FED have greater deficits in speech-in-noise perception compared to other subgroups of MCI. PMID: 30198228 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Factors Associated with Cheyne-Stokes Respiration in Acute Ischemic Stroke.
CONCLUSIONS: CSR frequently occurs in strokes involving large arteries or due to cardioembolism, regardless of the location and severity of the stroke. Predisposing conditions such as preexisting neurologic disability, low LVEF, and LA enlargement are associated with CSR in acute stroke. PMID: 30198229 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Muscle Thickness and Echo Intensity of the Abdominal and Lower Extremity Muscles in Stroke Survivors.
CONCLUSIONS: Our results indicate that quantitative and qualitative changes on the paretic side in stroke survivors were the most robust in the thigh muscles, whereas such changes might not occur in the abdominal muscles. PMID: 30198230 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Effects of Antiepileptic Drugs on Language Abilities in Benign Epilepsy of Childhood with Centrotemporal Spikes.
This study is to assess the responsiveness of electroencephalography (EEG) abnormalities and their effects on language ability after initiating different types of antiepileptic therapy in children with newly diagnosed benign epilepsy of childhood with centrotemporal spikes (BECTS). METHODS: The records of patients newly diagnosed with BECTS (n=120; 69 males) were reviewed retrospectively. The patients were randomly treated with lamotrigine, oxcarbazepine, or topiramate monotherapy, and underwent at least two EEG and standardized language tests. Effects were compared using Pearson's chi-square tests and paired t-tests. ...
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Characteristics of South Korean Patients with Hereditary Transthyretin Amyloidosis.
CONCLUSIONS: South Korean patients with hereditary TTR amyloidosis exhibited heterogeneous TTR genotypes and clinical phenotypes. The findings of this study suggest that the distribution of TTR amyloidosis in South Korea is due to de novo mutations and/or related to the other countries in East Asia. PMID: 30198232 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Clinical Predictors of Excessive Daytime Sleepiness in Patients with Parkinson's Disease.
CONCLUSIONS: Nighttime sleep problems, older age, and levodopa use are significantly associated with EDS in PD. A careful assessment and the management of sleep problems in PD patients might help to improve their quality of life. PMID: 30198233 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Determining the Etiology of Internuclear Ophthalmoplegia in a Patient with a Cardiac Pacemaker and Complex Neurological Presentation.
Authors: Nourbakhsh B, Cordano C, Renthal W PMID: 30198234 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Safe Childbirth after Taking Teriflunomide in a Woman with Multiple Sclerosis.
Authors: Cho BH, Lee SH PMID: 30198235 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

GNE Myopathy with Prominent Axial Muscle Involvement.
Authors: Park JM, Shin JH, Park JS PMID: 30198236 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Giant Cell Arteritis Associated Arteritic Anterior Ischemic Optic Neuropathy: Sudden Vision Loss on the Contralateral Side of Headache.
Authors: Lee EJ, Woo KA, Koo DL PMID: 30198237 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - September 11, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Age-Specific Cutoff Scores on a T1-Weighted Axial Medial Temporal-Lobe Atrophy Visual Rating Scale in Alzheimer's Disease Using Clinical Research Center for Dementia of South Korea Data.
This study aimed to determine the optimal cutoff score on a T1-weighted axial MTA Visual Rating Scale (VRS) for differentiating patients with AD from cognitively normal elderly people. METHODS: The 3,430 recruited subjects comprising 1,427 with no cognitive impairment (NC) and 2003 AD patients were divided into age ranges of 50-59, 60-69, 70-79, and 80-89 years. Of these, 446 participants (218 in the NC group and 228 in the AD group) were chosen by random sampling for inclusion in this study. Each decade age group included 57 individuals, with the exception of 47 subjects being included in the 80- to 89-year NC group. ...
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Adverse Events During Perampanel Adjunctive Therapy in Intractable Epilepsy.
CONCLUSIONS: Slow titration of perampanel may reduce perampanel-related adverse events. PMID: 29971974 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Clinical Presentations and Phenotypic Spectrum of Multiple Sclerosis at a University Hospital in Saudi Arabia.
CONCLUSIONS: MS presenting in the hospital setting is more common in KSA than reported previously, and the number of diagnosed cases in increasing. It is therefore an emerging and disabling neurological illness in KSA with clinical characteristics not dissimilar to those in other middle eastern countries. A decrease in the frequency of patients with secondary progressive multiple sclerosis (SPMS) indicates either that more new cases of RRMS are being diagnosed or that adequate treatments of RRMS are preventing the evolution to SPMS. Further larger and population-wide epidemiological and clinical studies with the long-term ...
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Effect of Vitamin D Deficiency on the Frequency of Headaches in Migraine.
Authors: Song TJ, Chu MK, Sohn JH, Ahn HY, Lee SH, Cho SJ Abstract BACKGROUND AND PURPOSE: The risk of vitamin D deficiency varies with the season. The frequency of vitamin D deficiency in migraine patients and its association with migraine are unclear. METHODS: We retrospectively evaluated first-visit migraine patients between January 2016 and May 2017, and investigated the demographics, season, migraine subtypes, frequency, severity, and impact of migraine, psychological and sleep variables, climate factors, and vitamin D levels. The nonfasting serum 25-hydroxyvitamin D concentration was measured to determine...
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

The Etiologies of Chronic Progressive Cerebellar Ataxia in a Korean Population.
CONCLUSIONS: This is the largest epidemiological study to analyze the frequencies of various cerebellar ataxias in a Korean population based on the large database of a tertiary hospital movement-disorders clinic in South Korea. These data would be helpful for clinicians in constructing diagnostic strategies and counseling for patients with cerebellar ataxias. PMID: 29971977 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Hand Tremor Questionnaire: A Useful Screening Tool for Differentiating Patients with Hand Tremor between Parkinson's Disease and Essential Tremor.
CONCLUSIONS: The developed Hand Tremor Questionnaire might be a good screening tool for hand tremors in patients with PD and ET. PMID: 29971978 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Clinical Application of 2017 McDonald Diagnostic Criteria for Multiple Sclerosis.
CONCLUSIONS: The new 2017 Multiple Sclerosis criteria may have an important impact in clinical practice with an earlier treatment to avoid the risk of disease dissemination. Their application requires a careful assessment to avoid misdiagnosis and mistreatments. PMID: 29971979 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Postoperative Transient Neurologic Dysfunction: A Proposal for Pathophysiology.
CONCLUSIONS: Transient neurologic dysfunction can occur during the postoperative period of brain surgery. Although this may last more than usual transient ischemic attack or seizure, it eventually resolves regardless of treatment. Based on our observation, we propose that this is the manifestation of the transient cortical depression triggered by mechanical stimulation, analogous to migraine aura associated with cortical spreading depression. PMID: 29971980 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Clinical Heterogeneity of Anti-GM2-Ganglioside-Antibody Syndrome.
CONCLUSIONS: This study has identified that anti-GM2 antibody can be found in various subtypes of GBS and its variants in rare cases. Compared to the clinical heterogeneity of the IgM-positive group, the IgG-positive group can be characterized by cranial-dominant GBS variants presenting mainly with oculomotor and vestibular dysfunctions. PMID: 29971981 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Mechanical Thrombectomy in Strokes with Large-Vessel Occlusion Beyond 6 Hours: A Pooled Analysis of Randomized Trials.
This study performed a pooled analysis of data from trials in which mechanical thrombectomy was performed beyond 6 hours from symptom onset. METHODS: We searched for randomized controlled trials that compared mechanical thrombectomy with the best medical treatment beyond 6 hours for ischemic strokes due to ELVO and reported on between 1990 and April 2018. The intervention group comprised patients treated with mechanical thrombectomy. Statistical analysis was conducted while pooling data and analyzing fixed- or random-effects models as appropriate. RESULTS: Four trials involving 518 stroke patients met the eligibili...
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Alanyl-tRNA Synthetase 2-Related Dementia with Selective Bilateral Frontal Cystic Leukoencephalopathy.
Authors: Carle G, Morin A, Noiray C, Roy-Joly P, Cohen L, Levy R, Samaan S, Nadjar Y PMID: 29971983 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

An Elderly Woman with Reversal of Clinical Presentation Mimicking Rapid-Onset Dystonia-Parkinsonism.
Authors: Ahn BJ, Kwon KY PMID: 29971984 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Near-Fatal Statin-Associated Autoimmune Myositis.
Authors: Vithayathil M, Phung A PMID: 29971985 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Crab Sign in Bilateral Extracranial Vertebral Artery Dissection.
Authors: Peters N, Engelter ST PMID: 29971986 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

The Impact of a National Healthcare System on the Doctor-Patient Relationship in Neurology.
Authors: Park JE PMID: 29971987 [PubMed] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - July 6, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Patterns of Orthostatic Blood Pressure Changes in Patients with Orthostatic Hypotension.
The objective of this study was to determine the patterns of blood pressure (BP) changes during the head-up tilt (HUT) test, particularly in terms of its clinical significance for patients with orthostatic hypotension (OH). METHODS: OH was divided into four categories based on systolic BP changes occurring within the first 10 minutes of the HUT test: sustained orthostatic hypotension (SOH), progressive orthostatic hypotension (POH), orthostatic hypotension with partial recovery (OHPR), and transient orthostatic hypotension (TOH). RESULTS: In total, 151 patients were analyzed: 65 with SOH, 38 with POH, 21 with OHPR,...
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Severe Hemifacial Spasm is a Predictor of Severe Indentation and Facial Palsy after Microdecompression Surgery.
CONCLUSIONS: Spasm severity does not predict surgical outcomes, but it can be used as a marker of pathologic compression in MVD for HFS, and be considered as a predictor of delayed facial palsy after MVD. PMID: 29856152 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Stimulation in Supplementary Motor Area Versus Motor Cortex for Freezing of Gait in Parkinson's Disease.
Authors: Kim SJ, Paeng SH, Kang SY Abstract BACKGROUND AND PURPOSE: Freezing of gait (FOG) is a frustrating problem in Parkinson's disease (PD) for which there is no effective treatment. Our aim was to find brain stimulation areas showing greater responses for reducing FOG. METHODS: Twelve PD patients with FOG were selected for inclusion. We explored the therapeutic effect of repetitive transcranial magnetic stimulation (rTMS) in the supplementary motor area (SMA) and the motor cortex (MC). We measured the number of steps, completion time, and freezing episodes during the stand-walk-sit test before and after rT...
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Sympathetic Overactivity Based on Heart-Rate Variability in Patients with Obstructive Sleep Apnea and Cerebral Small-Vessel Disease.
CONCLUSIONS: Our findings suggest that dysregulation of HRV, especially overactivation of sympathetic tone, could be a pathophysiologic mechanism underlying the development of WMC in OSA patients. PMID: 29856154 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial.
CONCLUSIONS: This study shows that treatment with unpolished-rice-germ-derived GABA improved not only the subjective sleep quality but also the objective sleep efficacy without severe adverse events. PMID: 29856155 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Secondary Short-Lasting Unilateral Neuralgiform Headache with Conjunctival Injection and Tearing: A New Case and a Literature Review.
In conclusion, the neurobiology of secondary SUNCT includes structures such as the nucleus and the trigeminal nerve with its branches, suggesting that some cases of primary SUNCT have underlying mechanisms that are related to existing focal damage that cannot be visualized. PMID: 29856156 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Interleukin-6, S-Nitrosothiols, and Neurodegeneration in Different Central Nervous System Demyelinating Disorders: Is There a Relationship?
CONCLUSIONS: These results confirm that IL-6 is activated in different demyelinating disorders, with this elevation being more prominent in the CSF of NMOSD with AQP4-IgG and ADEM patients. Moreover, S-nitrosylation is activated in demyelinating disorders with spinal-cord injury and neurodegeneration in these patients. However, we found no correlation between these biochemical markers, and so we could not confirm whether IL-6-mediated nitric oxide production is involved in spinal-cord lesions. PMID: 29856157 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Efficacy of Gaze Photographs in Diagnosing Ocular Myasthenia Gravis.
Authors: Ahn J, Park KS, Kim JS, Hwang JM Abstract BACKGROUND AND PURPOSE: The various tests that are routinely used to diagnose generalized myasthenia gravis, such as the edrophonium test, serum anti-acetylcholine-receptor antibodies (AChR-Ab), and repetitive nerve stimulation (RNS) tests, have lower diagnostic sensitivity in ocular myasthenia gravis (OMG). Diagnosing OMG becomes even more difficult when the clinical symptoms are subtle. There is no gold-standard diagnostic test available for OMG patients, and so this study compared the diagnostic sensitivity of gaze photographs with conventional tests in OMG. ...
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Recurrent Optic Neuritis as the Initial Symptom in Demyelinating Diseases.
CONCLUSIONS: A lower VFSS at the last medical appointment was predictive of MS. Patients with NMOSD and CRION have similar clinical characteristics, whereas NMOSD patients tend to have worse visual acuity. PMID: 29856159 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Applicability of McDonald 2010 and Magnetic Resonance Imaging in Multiple Sclerosis (MAGNIMS) 2016 Magnetic Resonance Imaging Criteria for the Diagnosis of Multiple Sclerosis in Sri Lanka.
CONCLUSIONS: MAGNIMS 2016 MRI criteria were superior to McDonald 2010 MRI criteria in specificity, accuracy, and PPV, but inferior in sensitivity and NPV. PMID: 29856160 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Incidence and Clinical Significance of Positional Downbeat Nystagmus in Posterior Canal Benign Paroxysmal Positional Vertigo.
CONCLUSIONS: Our study found transient pDBN in 40% of patients with PC BPPV after the immediate resolution of positional vertigo and pT-UBN. pDBN may be attributed to residual debris in the distal portion of the PC, which can move toward the ampulla producing an ampullopetal flow of endolymph during positioning. PMID: 29856161 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Measurement of the Optic Nerve Sheath Diameter with Magnetic Resonance Imaging and Its Association with Eyeball Diameter in Healthy Adults.
Authors: Kim DH, Jun JS, Kim R Abstract BACKGROUND AND PURPOSE: The optic nerve sheath diameter (ONSD) is an indirect marker of the intracranial pressure, but the normal range of ONSD as measured using magnetic resonance imaging (MRI) and its associations with clinical parameters and the eyeball transverse diameter (ETD) remain unclear. METHODS: We included 314 healthy adults who underwent brain MRI examinations for health screening between June 2014 and September 2017. The ONSD and ETD of each eye were calculated using time-of-flight magnetic resonance angiography. Linear regression analyses were performed to ...
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

A Psychiatric Side Effect of Levetiracetam Can Mimic a Relapse of Anti-Leucine-Rich Glioma Inactivated 1 Encephalitis.
Authors: Jang Y, Lee ST, Chu K, Lee SK PMID: 29856163 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Ultrasonography in the Early Diagnosis of Diabetic Lumbosacral Radiculoplexus Neuropathy.
Authors: An JY, Bae DW, Walker FO PMID: 29856164 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research

Agenesis of the Internal Carotid Artery Associated with Generalized Epilepsy.
Authors: La Spina P, Grillo F, Granata F, Casella C, Fazio MC, Colella M, Cotroneo M, Dell'Aera C, Ciacciarelli A, Vita G, Musolino R PMID: 29856165 [PubMed - as supplied by publisher] (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - June 2, 2018 Category: Neurology Tags: J Clin Neurol Source Type: research