Antithrombotic Treatment Following Intracerebral Hemorrhage in Patients With and Without Atrial Fibrillation Clinical Sciences

Background and Purpose— Patients who survive intracerebral hemorrhage (ICH) often have compelling indications for anticoagulant and antiplatelet medication. This nationwide observational study aimed to determine the extent and predictors of antithrombotic treatment after ICH in Sweden. Methods— Patients with a first-ever ICH in the Swedish Stroke Register (Riksstroke) 2005 to 2012 who survived hospital discharge were included. Riksstroke data were individually linked with other national registers to determine comorbid conditions and dispensed prescriptions of antithrombotic agents. Results— Among the 2777 patients with atrial fibrillation (AF), the proportion with a dispensed prescription of antithrombotic agents was 8.5% (anticoagulants) and 36.6% (antiplatelet agents) within 6 months and 11.1% (anticoagulants) and 43.6% (antiplatelet agents) within 1 year. Among the 11 268 patients without AF, the corresponding figures were 1.6% (anticoagulants) and 13.8% (antiplatelet agents) within 6 months and 2.0% (anticoagulants) and 17.5% (antiplatelet agents) within 1 year. In patients with AF, predictors of anticoagulant treatment were less severe ICH, younger age, previous anticoagulation, valvular disease, and previous ischemic stroke. High CHA2DS2-VASc (congestive heart failure, hypertension, age, diabetes mellitus, stroke [doubled], vascular disease, age, and sex category [female]) scores did not correlate with anticoagulant treatment. There was a positive co...
Source: Stroke - Category: Neurology Authors: Tags: Acute Cerebral Hemorrhage, Anticoagulants, Antiplatelets, Epidemiology Clinical Sciences Source Type: research

Related Links:

Conclusions: GCP patients (otherwise systemically healthy) were characterized by increased Th17-proinflammatory cell phenotype positive for the IL-23 receptor in peripheral blood. The proportion of Th17 cells that are negative for the IL-23 receptor in the peripheral blood of systemically healthy patients seemed to be unaffected by the presence or absence of chronic periodontitis.
Source: Journal of Applied Oral Science - Category: Dentistry Source Type: research
CONCLUSIONS: These findings emphasize the concern that psychiatric patients present an altered metabolic profile and that they do not receive adequate treatment for metabolic disruptions. Presence of metabolic disturbances should be routinely assessed, and adequate follow-up is needed to intervene early after illness onset. PMID: 32237298 [PubMed - in process]
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research
Anti‑glycolipid disorder effect of epigallocatechin‑3‑gallate on high‑fat diet and STZ‑induced T2DM in mice. Mol Med Rep. 2020 Mar 26;: Authors: Ren Z, Yang Z, Lu Y, Zhang R, Yang H Abstract Epigallocatechin-3-gallate (EGCG) is beneficial for inhibiting dyslipidemia and reducing hyperlipidemic risk. The purpose of the present study was to investigate the glycolipid regulatory effects and potential mechanisms of EGCG in a high‑fat diet and streptozotocin‑induced type 2 diabetes mellitus (T2DM) mouse model. The results demonstrated that EGCG can decrease blood glucose levels and i...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
CONCLUSION: Despite a reduction in the overall burden of depressive symptoms, the migrant subgroup population has a higher probability of presenting these symptoms. Mental health strategies for migrant women are a priority in Peru. PMID: 32237886 [PubMed - in process]
Source: Rural and Remote Health - Category: Rural Health Tags: Rural Remote Health Source Type: research
Authors: Godman B, McCabe H, D Leong T, Mueller D, Martin AP, Hoxha I, Mwita JC, Rwegerera GM, Massele A, Costa JO, do Nascimento RCRM, Lemos LLP, Tachkov K, Milushewa P, Patrick O, Niba LL, Laius O, Sefah I, Abdulsalim S, Soleymani F, Guantai AN, Achieng L, Oluka M, Jakupi A, Logviss K, Hassali MA, Kibuule D, Kalemeera F, Mubita M, Fadare J, Ogunleye OO, Saleem Z, Hussain S, Bochenek T, Mardare I, Alrasheedy AA, Furst J, Tomek D, Markovic-Pekovic V, Rampamba EM, Alfadl A, Amu AA, Matsebula Z, Phuong TNT, Thanh BN, Chichonyi Kalungia A, Zaranyika T, Masuka N, Olaru ID, Wale J, Hill R, Kurdi A, Timoney A, Campbell S, Meyer ...
Source: Expert Review of Pharmacoeconomics and Outcomes Research - Category: Health Management Tags: Expert Rev Pharmacoecon Outcomes Res Source Type: research
Conclusion: These finds highlight the role of ERAP1 in the pathogenesis of preeclampsia. PMID: 32239976 [PubMed - as supplied by publisher]
Source: Hypertension in Pregnancy - Category: OBGYN Tags: Hypertens Pregnancy Source Type: research
Authors: Huang YM, Shiyanbola OO, Chan HY, Smith PD Abstract Background: Type 2 diabetes (T2D) incurs tremendous health cost associated with various complications due to poor diabetes control. Medication adherence, which is correlated with patients' health literacy, should be consistently practiced achieving optimal diabetes control. A deeper understanding of the specific communication and psychosocial factors related to medication-taking behaviors across different levels of health literacy among people with T2D will guide the development of effective interventions and strategies to enhance medication adherence.Obj...
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
Conclusions: The home-visit simulation scenario was effective in providing students with a problem-solving experience in conditions similar to reality.Clinical Evidence: Further research is needed to develop various types of community simulation scenarios to enhance competency for community health practice. PMID: 32233948 [PubMed - in process]
Source: Journal of Community Health Nursing - Category: Nursing Tags: J Community Health Nurs Source Type: research
Publication date: Available online 2 April 2020Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Kannan Badri Narayanan, Gyu Tae Park, Sung Soo Han
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
J. Mater. Chem. A, 2020, Accepted Manuscript DOI: 10.1039/D0TA00871K, PaperJunquan Meng, Cher Hon Lau, Yunlong Xue, Rui Zhang, Bing Cao, pei li The incompatibility between hydrophobic polymers such as polytetrafluoroethylene (PTFE) and hydrophilic polymers like polyvinyl alcohol (PVA) is typically overcomed by reducing the large surface energy difference between these materials via... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - J. Mater. Chem. latest articles - Category: Chemistry Authors: Source Type: research
More News: Alcoholism | Atrial Fibrillation | Bleeding | Cardiology | Congestive Heart Failure | Diabetes | Diabetes Mellitus | Endocrinology | Epidemiology | Heart | Heart Failure | Hemorrhagic Stroke | Hypertension | Ischemic Stroke | Liver | Neurology | Stroke | Study | Urology & Nephrology