Serum Albumin Is Negatively Associated with Hemorrhagic Transformation in Acute Ischemic Stroke Patients
Conclusions: Higher serum albumin is associated with lower HT risk in a dose-dependent manner in AIS patients younger than 60 years.Cerebrovasc Dis 2019;47:88 –94 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - March 22, 2019 Category: Neurology Source Type: research

Editorial
Cerebrovasc Dis 2019;47:I (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - March 21, 2019 Category: Neurology Source Type: research

A COACHS Nomogram to Predict the Probability of Three-Month Unfavorable Outcome after Acute Ischemic Stroke in Chinese Patients
Conclusions: The COACHS nomogram may be used to predict unfavorable outcome at 3 months after acute ischemic stroke in Chinese population. It may be also a reliable tool that is effective in its clinical utilization to risk-stratify acute stroke patients.Cerebrovasc Dis 2019;47:80 –87 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - March 21, 2019 Category: Neurology Source Type: research

Serotonergic Regulation and Cognition after Stroke: The Role of Antidepressant Treatment and Genetic Variation
Conclusion: There was no difference in cognition between citalopram and placebo-treated patients according to the genotype group. Our results indicate, however, that low expression SERT genotype may contribute to reduced cognitive function post stroke as placebo-treated patients with low SERT expression tended to score lower on the SDMT. The significant difference in SDMT scores between low and high expression patients was present only in the placebo-treated group, thereby warranting further exploration of the potential effect of early citalopram treatment on cognitive functioning. Our results are preliminary and need repl...
Source: Cerebrovascular Diseases - March 7, 2019 Category: Neurology Source Type: research

Endovascular Thrombectomy in the Elderly: Do Radiological and Clinical Outcomes Differ from Those in Younger Patients? A Prospective Single-Center Experience
Conclusions: EVT in the elderly resulted in equally notable neurological improvement as compared to younger patients. Although the elderly had a higher mortality rate and fewer favorable clinical outcomes at 3 month follow-up, a strict upper age limit for EVT seems unjustified.Cerebrovasc Dis 2019;47:65 –71 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - February 26, 2019 Category: Neurology Source Type: research

Renal Impairment Is Associated with Intracerebral Hemorrhage after Mechanical Thrombectomy in Vertebrobasilar Stroke
Conclusions: Patients with RD and acute vertebrobasilar stroke should be thoroughly monitored to prevent ICH after thrombectomy. Our results support performing mechanical thrombectomy in acute stroke patients with large vessel occlusions of the posterior circulation, irrespective of their renal function.Cerebrovasc Dis 2019;47:48 –56 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - February 15, 2019 Category: Neurology Source Type: research

Reduced Hypoxic Tissue and Cognitive Improvement after Revascularization Surgery for Chronic Cerebral Ischemia
Conclusions: Hypoxic tissue is reduced following the restoration of cerebral perfusion with revascularization surgery in patients with severe atherosclerotic stenosis of the cervical ICA. The reduction in hypoxic tissue is associated with cognitive improvement in such patients.Cerebrovasc Dis 2019;47:57 –64 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - February 15, 2019 Category: Neurology Source Type: research

Associations of High Intensities on Magnetization-Prepared Rapid Acquisition with Gradient Echo with Aortic Complicated Lesions in Ischemic Stroke Patients
Conclusions: High intensities on T1WI with MPRAGE in the aortic arch were significantly associated with the presence of ACLs. An evaluation of the aortic arch using MPRAGE may be useful for predicting ACLs.Cerebrovasc Dis 2019;47:15 –23 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - February 14, 2019 Category: Neurology Source Type: research

Impact of Baseline Features and Risk Factor Control on Cognitive Function in the Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis Trial
Conclusion: Cognitive impairment is common in patients with severe symptomatic intracranial atherosclerosis. Physical inactivity at baseline and during follow-up is a strong predictor of cognitive impairment.Cerebrovasc Dis 2019;47:24 –31 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - February 14, 2019 Category: Neurology Source Type: research

Liver Fibrosis, Not Steatosis, Associates with Long-Term Outcomes in Ischaemic Stroke Patients
Conclusions: This study found that the burden of liver fibrosis but not that of steatosis, assessed via TE, was an independent predictor of all-cause and cardiovascular mortality during long-term follow-up in patients with ischaemic stroke.Cerebrovasc Dis 2019;47:32 –39 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - February 14, 2019 Category: Neurology Source Type: research

One-Year Risk of Recurrent Stroke and Death Associated with Vertebrobasilar Artery Stenosis and Occlusion in a Cohort of 10,515 Patients
Conclusions: VBA stenosis or occlusion was relatively prevalent among patients with TIA or ischemic stroke and associated with higher risk of recurrent stroke and death in patients with ischemic stroke or TIA who had large artery atherosclerosis.Cerebrovasc Dis 2019;47:40 –47 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - February 14, 2019 Category: Neurology Source Type: research

Using the Region of Interest from Time-of-Flight Magnetic Resonance Angiography to Differentiate Between Intracranial Arterial Dissection and True Atherosclerotic Stenosis
Conclusion: The ROI difference value from 3D TOF MRA could help distinguish between dissection and atherosclerosis. If the ROI difference value from 3D TOF MRA is small (#x3c; 99.0), detailed testing should be performed to identify dissection.Cerebrovasc Dis 2019;47:8 –14 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - February 7, 2019 Category: Neurology Source Type: research

Contents Vol. 46, 2018
Cerebrovasc Dis 2018;46:I –VI (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - February 1, 2019 Category: Neurology Source Type: research

Risks of Acute Stroke Treatment in Patients with Cardiac Disease
Cerebrovasc Dis 2018;46:I (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - January 18, 2019 Category: Neurology Source Type: research

Returning to Unpaid Work after Stroke: The Psychosocial Outcomes in Stroke Cohort Study
Conclusions: More women are engaged in unpaid work before and at 12 months after stroke, but there is a reduction in the proportion of women returning to unpaid work at 12 months not seen in men. Consideration may need to be given to the development of rehabilitation strategies targeted at the specific needs of stroke survivors.Cerebrovasc Dis 2019;47:1 –7 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - January 17, 2019 Category: Neurology Source Type: research

Adenosine Deaminase Two and Immunoglobulin M Accurately Differentiate Adult Sneddon ’s Syndrome of Unknown Cause
Conclusion: Serum IgM levels might be used as a triage tool and plasma ADA2 activity performs perfectly as a diagnostic test for DADA2 in adult patients within the SnS spectrum. ADA2 activity in plasma also reliably distinguishes HHZ from HC.Cerebrovasc Dis 2018;46:257 –264 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - January 16, 2019 Category: Neurology Source Type: research

Intra-Plaque Vessels on Contrast-Enhanced Ultrasound Sonography Predict Carotid Plaque Histology
Conclusion: Vas-S values of 0 and 2 at 1 min indicated unruptured and healed plaques respectively. Thus, a Vas-S of 1 at 1 min is an indicator of a ruptured plaque. The intra-plaque vessel size on CEUS was significantly associated with carotid plaque histology, and may predict the process of plaque rupture and restoration.Cerebrovasc Dis 2018;46:265 –269 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - January 16, 2019 Category: Neurology Source Type: research

Thrombus Enhancement Is a Predictor of Clinical Outcome in Acute Ischemic Stroke after Mechanical Thrombectomy
Conclusions: CE of thrombi – especially in a range from over 18.4 to 40.35 Hounsfield Units – is an independent predictor of poor clinical outcome in patients undergoing MT due to acute middle cerebral artery occlusion.Cerebrovasc Dis 2018;46:270 –278 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - January 16, 2019 Category: Neurology Source Type: research

The Relationship between Blood Pressure Variability, Recanalization Degree, and Clinical Outcome in Large Vessel Occlusive Stroke after an Intra-Arterial Thrombectomy
Conclusions: Short-term BPV over 24 and 48 h after IAT in acute ischemic stroke patients was related to recanalization degree, and END occurrence, and may be an independent predictor of clinical outcome.Cerebrovasc Dis 2018;46:279 –286 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - January 16, 2019 Category: Neurology Source Type: research

Cholesterol Crystals in Embolic Debris are Associated with Postoperative Cerebral Embolism after Carotid Artery Stenting
Conclusions: Cholesterol crystals were common in the embolic debris from patients with postoperative ischemic lesions after CAS. These results suggest that inflammatory destabilization of the intraplaque lipid component is related to postprocedural DWI lesions.Cerebrovasc Dis 2018;46:242 –248 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - January 2, 2019 Category: Neurology Source Type: research

Baseline Characteristics and Readmissions after Cerebral Venous Sinus Thrombosis in a Nationally Representative Database
Conclusions: We provide baseline characteristics and readmission rates after CVST over a 1-year period. In-hospital mortality rate and association with pregnancy were lower than previously observed.Cerebrovasc Dis 2018;46:249 –256 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - January 2, 2019 Category: Neurology Source Type: research

Cervical Artery Dissection in Patients of African Ancestry
Conclusion: AA patients represent a smaller proportion of CeAD cases compared to young stroke cases at our center. AA patients suffering CeAD have higher prevalence of both vascular risk factors and frequency of the CeAD risk allele compared to EA patients. These findings suggest a complex interplay between traditional vascular risk factors and genetic predisposition underlying CeAD pathogenesis. Further prospective research is needed to clarify these associations and disparities.Cerebrovasc Dis 2018;46:218 –222 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - December 5, 2018 Category: Neurology Source Type: research

Left-Sided Atrial Septal Pouch as a Risk Factor of Cryptogenic Stroke: A Systematic Review and Meta-Analysis
Conclusion: Our meta-analysis demonstrated association between LSSP and cryptogenic stroke. In our univariate analysis, the risk of cryptogenic stroke is higher among patients with LSSP than in cases without the LSSP.Cerebrovasc Dis 2018;46:223 –229 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - December 5, 2018 Category: Neurology Source Type: research

A Systematic Review and Meta-Analysis of Molecular Biomarkers Associated with Early Neurological Deterioration Following Acute Stroke
Background: Early neurological deterioration (END) following acute stroke is associated with poorer long-term outcomes. Identification of patients at risk could assist early monitoring and treatment decisions. This review summarised the evidence describing non-radiological biomarkers for END.Summary: Electronic searches from January 1990 to March 2017 identified studies reporting a blood/cerebrospinal fluid (CSF)/urine biomarker measurement within 24 h of acute stroke and at least 2 serial assessments of clinical neurological status (#x3c; 24 h and #x3c; 7 days). Out of 12,895 citations, 82 studies were included, mostly fo...
Source: Cerebrovascular Diseases - December 5, 2018 Category: Neurology Source Type: research

The Management of Acute Ischemic Strokes and the Prevalence of Large Vessel Occlusion in Left Ventricular Assist Device
Conclusions: In-hospital strokes and acute LVOs are common in LVAD-associated AIS. Prompt evaluation with CTA and endovascular therapy should be pursued for these critically ill patients.Cerebrovasc Dis 2018;46:213 –217 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - December 4, 2018 Category: Neurology Source Type: research

Coincidence and Management of Non-Motor Stroke-Associated Risks (Dysphagia – Swallowing Deficits – Visual Neglect)
Cerebrovasc Dis 2018;46:I (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - November 15, 2018 Category: Neurology Source Type: research

Letter to the Article by Maus et al.: “Order of Treatment Matters in Ischemic Stroke: Mechanical Thrombectomy First, Then Carotid Artery Stenting for Tandem Lesions of the Anterior Circulation”
Cerebrovasc Dis 2018;46:210 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - November 12, 2018 Category: Neurology Source Type: research

Challenge of Attaining Flow Arrest in Anterior Circulation Tandem Occlusions in Large Vessel Ischemic Stroke: Wedged SAVE Technique
Cerebrovasc Dis 2018;46:211 –212 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - November 12, 2018 Category: Neurology Source Type: research

The Impact of Cerebral Atherosclerosis According to Location on Prognosis after Coronary Artery Bypass Grafting
Conclusions: Over 10 years of follow-up, cerebral atherosclerosis significantly associated with the development of adverse outcomes after CABG. The prognostic value of ICAS might be different from that of ECAS; immediate post-CABG stroke was more closely associated with ICAS, whereas there was a closer association between long-term post-CABG mortality and ECAS.Cerebrovasc Dis 2018;46:200 –209 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - November 8, 2018 Category: Neurology Source Type: research

Ten-Year Evaluation of the TOYOTA Prehospital Stroke Scale for Tissue Plasminogen Activator Intravenous Therapy in the Real World
Conclusions: The TOPSPIN is a simple prehospital stroke scale that includes an assessment of atrial fibrillation. Detection of atrial fibrillation in the prehospital stage may point to a higher probability of ischemic stroke.Cerebrovasc Dis 2018;46:184 –192 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - November 1, 2018 Category: Neurology Source Type: research

Safety of Endovascular Thrombectomy for Acute Ischaemic Stroke in Anticoagulated Patients Ineligible for Intravenous Thrombolysis
Conclusion: Mechanical thrombectomy appears to be safe and effective in anticoagulated patients ineligible for thrombolysis, with observed haemorrhage rates similar to those of patients not on anticoagulant therapy. However, further multicentre prospective studies are needed, due to the rising number of patients on warfarin and DOACs worldwide.Cerebrovasc Dis 2018;46:193 –199 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - November 1, 2018 Category: Neurology Source Type: research

Transcranial Magnetic Stimulation as an Intervention Tool to Recover from Language, Swallowing and Attentional Deficits after Stroke: A Systematic Review
Background: Following a stroke event, patients often are severely affected by disabilities that hinder their quality-of-life. There are currently several rehabilitative options and strategies, and it is crucial to find the most effective interventions. The applicability of transcranial magnetic stimulation (TMS) to the recovery of nonmotor functions such as communication skills, swallowing ability and spatial attention after stroke remains important clinical questions.Summary: We searched PubMed and ISI Web of Science for articles that used repetitive TMS protocols to rehabilitate post-stroke deficits. We analysed qualitat...
Source: Cerebrovascular Diseases - October 19, 2018 Category: Neurology Source Type: research

Endovascular Clot Retrieval by Hub-and-Spoke Service Delivery is Feasible Compared with Direct-to-Mothership
Conclusion: This state-wide service model demonstrates comparable clinical outcomes to that described in clinical trials. We found no significant difference in outcome between patients directly admitted to CSC and those with “hub-and-spoke” service delivery.Cerebrovasc Dis 2018;46:170 –175 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - October 9, 2018 Category: Neurology Source Type: research

< b > < i > ACTA2 < /i > < /b > Cerebral Arteriopathy: Not Just a Puff of Smoke
Background: Missense mutations in the gene that codes for smooth muscle actin,ACTA2, cause diffuse smooth muscle dysfunction and a distinct cerebral arteriopathy collectively known as multisystemic smooth muscle dysfunction syndrome (MSMDS). Until recently,ACTA2 cerebral arteriopathy was considered to be a variant of moyamoya disease. However, recent basic science and clinical data have demonstrated that the cerebral arteriopathy caused by mutantACTA2 exhibits genetic loci, histopathology, neurological sequelae, and radiographic findings unique from moyamoya disease. We conducted a literature review to provide insight into...
Source: Cerebrovascular Diseases - October 9, 2018 Category: Neurology Source Type: research

Effect of Combined Treatment with MLC601 (NeuroAiDTM) and Rehabilitation on Post-Stroke Recovery: The CHIMES and CHIMES-E Studies
Conclusions: More subjects on MLC601 improved to functional independence compared to placebo among subjects receiving persistent rehabilitation up to M3. The larger treatment effect of MLC601 was sustained over 2  years which supports the hypothesis that MLC601 combined with rehabilitation might have beneficial and sustained effects on neuro-repair processes after stroke. There is a need for more data on the effect of combining rehabilitation programs with stroke recovery treatments.Cerebrovasc Dis 2018;46:82 –88 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - October 5, 2018 Category: Neurology Source Type: research

Predicting Dysphagia with National Institute of Health Stroke Scale: Distinction between Infra- and Supratentorial Region is Essential
Conclusions: NIH-SS may be used as an adjunct to predict dysphagia in acute stroke patients with moderate sensitivity and specificity. Differentiation between supra- and infratentorial regions is essential not to miss dysphagia in infratentorial stroke.Cerebrovasc Dis 2018;46:150 –158 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - October 5, 2018 Category: Neurology Source Type: research

Insulin Resistance Index from Oral Glucose Tolerance Test Predicts Ischemic Stroke Outcomes in Non-Diabetic Patients with Different Estimated Glomerular Filtration Rate Strata
Conclusions: An OGTT-derived estimate of insulin resistance with the composite ISI, but not HOMA-IR, was independently associated with increased risks of 1-year mortality and poor functional outcome in non-diabetic ischemic stroke patients with different eGFR strata.Cerebrovasc Dis 2018;46:140 –149 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - September 20, 2018 Category: Neurology Source Type: research

Mechanical Thrombectomy in Acute Stroke Due to Carotid Occlusion: A Series of 153 Consecutive Patients
Conclusions: In our population, patients with CAO clinically present with severe strokes. Isolated occlusions of the extra- or intracranial segments of the carotid are more frequent than tandem occlusions. Successful recanalization after thrombectomy is achieved in most of the patients, but association with favorable functional outcome is poor. Clinical evolution is similar in patients treated with PMT and BT. Intracranial symptomatic hemorrhage after treatment is associated with higher intrahospital mortality and worse 3 months-mRS. Poor perfusion-CT mismatch, symptomatic hemorrhage, and isolated CAO are independent predi...
Source: Cerebrovascular Diseases - September 17, 2018 Category: Neurology Source Type: research

Impact of Dysphagia Assessment and Management on Risk of Stroke-Associated Pneumonia: A Systematic Review
Background: Patients with dysphagia are at an increased risk of stroke-associated pneumonia. There is wide variation in the way patients are screened and assessed during the acute phase. The aim of this review was to identify the methods of assessment and management in acute stroke that influence the risk of stroke-associated pneumonia. Studies of stroke patients that reported dysphagia screening, assessment or management and occurrence of pneumonia during acute phase stroke were screened for inclusion after electronic searches of multiple databases from inception to November 2016. The primary outcome was association with ...
Source: Cerebrovascular Diseases - September 10, 2018 Category: Neurology Source Type: research

Patterns and Outcomes of the Top of the Basilar Artery Syndrome: The Role of the Posterior Communicating Artery
Conclusion: Patterns and clinical outcomes of TOB vary and are affected by the hemodynamic status of the arterial system, such as BA recanalization and the presence of textbook-type PcoA.Cerebrovasc Dis 2018;46:106 –115 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - September 10, 2018 Category: Neurology Source Type: research

Early Achievement of Blood Pressure Lowering and Hematoma Growth in Acute Intracerebral Hemorrhage: Stroke Acute Management with Urgent Risk-Factor Assessment and Improvement-Intracerebral Hemorrhage Study
Conclusions: Early achievement of target SBP #x3c; 160 mm Hg is associated with a lower risk of hematoma growth in ICH.Cerebrovasc Dis 2018;46:116 –122 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - September 10, 2018 Category: Neurology Source Type: research

Hypercoagulation on Thromboelastography Predicts Early Neurological Deterioration in Patients with Acute Ischemic Stroke
Conclusion: Decreased R time on admission TEG is associated with END within 3 days in patients with acute ischemic stroke.Cerebrovasc Dis 2018;46:123 –129 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - September 10, 2018 Category: Neurology Source Type: research

Title Page
Cerebrovasc Dis 2018;46:I –II (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - September 7, 2018 Category: Neurology Source Type: research

Asia Pacific Stroke Conference 2018. Abstracts of the Annual Conference of the Asia Pacific Stroke Organization (APSO). Jakarta, Indonesia, September 6-9, 2018
Cerebrovasc Dis 2018;46:1 –49 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - September 7, 2018 Category: Neurology Source Type: research

Effect of Combined Treatment with MLC601 (NeuroAiD < sup > TM < /sup > ) and Rehabilitation on Post-Stroke Recovery: The CHIMES and CHIMES-E Studies
Conclusions: More subjects on MLC601 improved to functional independence compared to placebo among subjects receiving persistent rehabilitation up to M3. The larger treatment effect of MLC601 was sustained over 2  years which supports the hypothesis that MLC601 combined with rehabilitation might have beneficial and sustained effects on neuro-repair processes after stroke. There is a need for more data on the effect of combining rehabilitation programs with stroke recovery treatments.Cerebrovasc Dis 2018;46:82 –88 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - September 7, 2018 Category: Neurology Source Type: research

Onset to Reperfusion Time Was Not Important in Mechanical Thrombectomy for Elderly Patients: A Retrospective Multicenter Study in Tama Area, Tokyo
Conclusions: In MT for elderly patients, effective recanalization improved the patients ’ outcome but OTR affected less. Further studies are warranted to establish the appropriate patient selection and treatment strategies.Cerebrovasc Dis 2018;46:89 –96 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - September 7, 2018 Category: Neurology Source Type: research

Peak Troponin I Levels Are Associated with Functional Outcome in Intracerebral Hemorrhage
Conclusions: Troponin I elevations during hospital stay occur frequently in ICH patients and are independently associated with functional outcome after 3 and 12 months but not with mortality.Cerebrovasc Dis 2018;46:72 –81 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - August 23, 2018 Category: Neurology Source Type: research

Telestroke in Catalonia: Increasing Thrombolysis Rate and Avoiding Interhospital Transfers
Conclusions: Telestroke favors safe and effective thrombolysis, helps to increase the population rate of IVT, and avoids a large number of interhospital transfers.Cerebrovasc Dis 2018;46:66 –71 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - August 22, 2018 Category: Neurology Source Type: research

Delayed Intravenous Thrombolysis in Patients with Minor Stroke
Conclusions: Our findings show that the door-to-needle time was longer in patients with minor stroke than it was in those with non-minor stroke, mainly owing to delayed action in the initial steps of neurology notification and imaging. Our findings suggest that some quality improvement initiatives are necessary for patients with suspected stroke with minor symptoms.Cerebrovasc Dis 2018;46:52 –58 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - August 10, 2018 Category: Neurology Source Type: research

Order of Treatment Matters in Ischemic Stroke: Mechanical Thrombectomy First, Then Carotid Artery Stenting for Tandem Lesions of the Anterior Circulation
Conclusion: Mechanical thrombectomy prior to acute CAS in TO is a predictive factor for favorable clinical outcome at 90 days.Cerebrovasc Dis 2018;46:59 –65 (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - August 10, 2018 Category: Neurology Source Type: research