Both Ends of Values in the Hemoglobin Spectrum Are Associated with Adverse Stroke Outcomes
Conclusions: Our study found both low and high hemoglobin values were associated with adverse stroke outcomes including all-cause mortality, stroke recurrence, combined endpoint, and stroke disability, which showed a U-shaped association. And, significant interactions between sex and hemoglobin concentration on all-cause mortality and stroke recurrence were also identified.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - August 18, 2021 Category: Neurology Source Type: research

Contemporary Trends in the Treatment of Mild Ischemic Stroke with Intravenous Thrombolysis: Paul Coverdell National Acute Stroke Program
Conclusion: There was an increased trend in IVT utilization among AIS patients presenting with mild symptoms. Utilization of IVT increased the odds of being discharged to home and the ability to ambulate at discharge independently in patients with mild stroke.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - August 17, 2021 Category: Neurology Source Type: research

PROGRESS in Blood Pressure Control for the Prevention of Secondary Stroke
Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - August 12, 2021 Category: Neurology Source Type: research

Treat COVID-19, but Not Only COVID-19: Stroke Matters as Well
Conclusion: Even with a low burden of COVID-19 during the first wave and no change in organization and logistics of stroke services, stroke admissions and volume of recanalization treatments decreased. Public health communication campaigns should encourage people to seek emergency medical care for stroke symptoms during the COVID-19 pandemic.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - August 11, 2021 Category: Neurology Source Type: research

A History of Cerebrovascular Disease Is Independently Associated with Increased Morbidity and Mortality in Patients with COVID-19: A Cohort Study of 369,563 COVID-19 Cases in the USA
Conclusions: CVD, a known complication of CO ­VID-19, is more frequent in patients with a prior history of CVD. Patients with any previous diagnosis of CVD are at higher risks of morbidity and mortality from COVID-19 infection. In patients admitted to the ED due to COVID-19 symptoms, these risk factors should be promptly identified as delayed or missed risk stratification and could lead to an ineffective and untimely diagnosis of subsequent CVD, which would lead to protracted hospitalization and poor prognosis.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - August 6, 2021 Category: Neurology Source Type: research

p53 Inhibition Provides a Pivotal Protective Effect against Cerebral Ischemia-Reperfusion Injury via the Wnt Signaling Pathway
Conclusion: We confirmed in vivo and in vitro that inhibition of p53 has a protective effect on the cerebral ischemia-reperfusion injury, which may be related to the activation of the Wnt signaling pathway.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - August 2, 2021 Category: Neurology Source Type: research

Editorial
Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - August 2, 2021 Category: Neurology Source Type: research

Association between Stroke Quality Assessments and Mortality within 30 Days among Patients Who Underwent Hemorrhagic Stroke Surgeries in South Korea
Conclusions: The study identified a significant relationship between stroke quality assessments and 30-day mortality. Healthcare organizations without stroke quality assessments may exhibit a comparatively higher risk of mortality. Future interventions to minimize mortality and provide evidence for policymakers and healthcare leaders could involve expanding the scope of stroke quality assessment.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - July 30, 2021 Category: Neurology Source Type: research

Workflow Times and Outcome of Endovascular Therapy in Stroke Patients with Initial MRI or CT
Conclusion: In LVO stroke patients undergoing ET, pretreatment imaging with MRI instead of CT leads to a delay of imaging acquisition after hospital admission without having a measurable impact on consecutive workflow steps and clinical outcome.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - July 30, 2021 Category: Neurology Source Type: research

Is Measuring Risk Marker Progression Useful for Cardiovascular Disease Prediction?
Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - July 30, 2021 Category: Neurology Source Type: research

Relationship between Chronic Kidney Disease, Time-in-Therapeutic Range, and Adverse Outcomes in Atrial Fibrillation: A post hoc Analysis from the AMADEUS Trial
Conclusion: Deteriorated renal function has a small negative impact on the quality of anticoagulation control with VKA which is linked to poor outcomes in AF. However, moderate renal failure itself was an independent risk factor for increased risk of stroke, major bleeding, and all-cause mortality amongst patients with AF.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - July 28, 2021 Category: Neurology Source Type: research

Evolution of Evidence-Based Medicine in Stroke
The introduction and evolution of evidence-based stroke medicine has realized major advances in our knowledge about stroke, methods of medical research, and patient outcomes that continue to complement traditional individual patient care. It is humbling to recall the state of knowledge and scientific endeavour of our forebears who were unaware of what we know now and yet pursued the highest standards for evaluating and delivering effective stroke care. The science of stroke medicine has evolved from pathophysiological theory to empirical testing. Progress has been steady, despite inevitable disappointments and cul-de-sacs,...
Source: Cerebrovascular Diseases - July 27, 2021 Category: Neurology Source Type: research

Trends in Literature on Cerebral Bypass Surgery: A Systematic Review
Conclusion: Clinical studies on cerebral bypass surgery have become increasingly popular in the past decades. Since the introduction of moyamoya as a distinct pathologic entity, Asian countries in particular have a very active community regarding this disease, with an increasing number of articles published every year. Studies on bypass for chronic steno-occlusive disease peaked in the 1980s but have remained the main focus of bypass research, particularly in many European departments. The number of reports published on these bypass operations significantly decreased after the FDA approval of flow diverters for aneurysm tr...
Source: Cerebrovascular Diseases - July 21, 2021 Category: Neurology Source Type: research

Association of Admission NIHSS Score with Infarct Core Volume and Target Mismatch of Infarct Core/Penumbra Volume on CT Perfusion in Acute Ischaemic Stroke
Conclusion: aNIHSS may be a useful tool to predict an ICV #x3c; 70 mL and TMM on CTP in AIS patients.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - July 21, 2021 Category: Neurology Source Type: research

Beyond Functional Impairment: Redefining Favorable Outcome in Patients with Subarachnoid Hemorrhage
Conclusion: Established stroke scores mainly focusing on functional outcomes do poorly reflect the high rate of subjective impairments reported in SAH survivors, specifically in those achieving good functional outcome. Further studies are needed to investigate whether psychoeducational approaches aiming at improving coping mechanisms and perceived self-efficacy may result in higher subjective health in these patients.Cerebrovasc Dis (Source: Cerebrovascular Diseases)
Source: Cerebrovascular Diseases - July 20, 2021 Category: Neurology Source Type: research