Microbleeds after Carotid Artery Stenting: Small Embolism May Induce Cerebral Microbleeds
Conclusions: We found that new cerebral microbleeds developed after CAS and that these might be associated with new ischemic lesions, mostly in the territory of the treated carotid artery. We speculate that these microbleeds result from the deoxygenation of hemoglobin in the embolus or, alternatively, small hemorrhagic transformation of ischemic lesions.Cerebrovasc Dis Extra 2019;9:57 –65 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - June 14, 2019 Category: Neurology Source Type: research

Stent Retriever Thrombectomy Potentially Increases the Recanalization Rate, Improves Clinical Outcome, and Decreases Mortality in Acute Basilar Occlusion: A Systematic Review and Meta-Analysis
Conclusions: The data from this meta-analysis suggest a possible superiority of SRT over IVT, pending positive results of randomized controlled trials. According to international recommendations, patients with BAO should preferentially be treated with SRT; if no contraindications exist, IVT should not be withheld.Cerebrovasc Dis Extra 2019;9:46 –56 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - June 5, 2019 Category: Neurology Source Type: research

Cardiac Magnetic Resonance Imaging in Patients with Acute Ischemic Stroke and Elevated Troponin: A TRoponin ELevation in Acute Ischemic Stroke (TRELAS) Sub-Study
Conclusions: The TRELAS sub-study indicates that noninvasive cardiac MRI may provide helpful information to identify stroke patients with or without acute coronary syndrome. Our findings might help to select stroke patients in urgent need of coronary angiography.Cerebrovasc Dis Extra 2019;9:19 –24 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - May 5, 2019 Category: Neurology Source Type: research

Increased Plasma VEGF Levels in Patients with Cerebral Large Artery Disease Are Associated with Cerebral Microbleeds
Conclusions: In patients with CLAD, elevated plasma VEGF might be associated with CMBs, especially those located in the cortex and/or at the gray-white junction.Cerebrovasc Dis Extra 2019;9:25 –30 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - May 5, 2019 Category: Neurology Source Type: research

Nonsteroidal Anti-Inflammatory Drugs: A Potential Pharmacological Treatment for Intracranial Aneurysm
Background: Saccular intracranial aneurysms (IAs) are outpouchings of the vessel wall of intracranial arteries. Rupture of IAs results in subarachnoid hemorrhage which is associated with high morbidity and mortality. Surgical interventions, such as clipping and coiling, have associated risks. Currently, there are no proven pharmacological treatments to prevent the growth or rupture of IAs. Infiltration of proinflammatory cytokines in response to increased wall sheer stress is a hallmark of IA. Nonsteroidal anti-inflammatory drugs (NSAIDs) are being investigated as potential therapeutic agents for reduction in growth and/or...
Source: Cerebrovascular Diseases Extra - May 5, 2019 Category: Neurology Source Type: research

Circulating Microparticles in Patients with Symptomatic Carotid Disease Are Related to Embolic Plaque Activity and Recent Cerebral Ischaemia
Conclusions: PMP and EMP were associated with stroke and recent cerebrovascular events (DWI+) but only PMP were also associated with ongoing (MES+) thrombo-embolic activity suggesting a differential biomarker potential for EMP to index cerebral ischaemia while PMP may predict on-going thrombo-embolic activity.Cerebrovasc Dis Extra 2019;9:9 –18 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - April 3, 2019 Category: Neurology Source Type: research

Health Economic Evaluations of Digital Health Interventions for Secondary Prevention in Stroke Patients: A Systematic Review
Background: In the first 5 years after their stroke, about a quarter of patients will suffer from a recurrent stroke. Digital health interventions facilitating interactions between a caregiver and a patient from a distance are a promising approach to improve patient adherence to lifestyle changes proposed by secondary prevention guidelines. Many of these interventions are not implemented in daily practice, even though efficacy has been shown. One of the reasons can be the lack of clear economic incentives for implementation. We propose to map all health economic evidence regarding digital health interventions for secondary...
Source: Cerebrovascular Diseases Extra - January 13, 2019 Category: Neurology Source Type: research

Transient Ischaemic Attack Rarely Precedes Stroke in a Cohort with Low Proportions of Large Artery Atherosclerosis: A Population-Based Study
Conclusion: In our population-based cohort, rates of TIA preceding ischaemic stroke were much lower than previously reported, probably reflective of effective secondary prevention (active TIA clinics) and primary prevention (limiting LAA prevalence). In our population, further enhancements in TIA care will be of limited yield.Cerebrovasc Dis Extra 2018;8:101 –105 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - August 23, 2018 Category: Neurology Source Type: research

A Novel Intraoperative Laser Light Imaging System to Simultaneously Visualize Visible Light and Near-Infrared Fluorescence for Indocyanine Green Videoangiography
Conclusions: Using the present setup, we can observe the color operative field and enhanced blood flow using ICG in real time. This setup could facilitate various cerebrovascular surgeries.Cerebrovasc Dis Extra 2018;8:96 –100 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - July 27, 2018 Category: Neurology Source Type: research

Effect of Exercise on Physical Recovery of People with Locked-In Syndrome after Stroke: What Do We Know from the Current Evidence? A Systematic Review
Conclusion: Studies indicate a positive trend of effect of exercise for physical recovery of people with LIS after stroke including the improvement of muscle strength, tone, walking ability, and activity in daily living. Mixed physical exercises were used. The effects were not significant. No adverse event has been reported. The quality of the existing evidence is relatively low since the papers were either case series or case studies. Further studies are needed on exercise types and dosages for better prescriptions for people with LIS after stroke. This may help to extend their lives with better control of the complicatio...
Source: Cerebrovascular Diseases Extra - July 13, 2018 Category: Neurology Source Type: research

Cerebral Haemodynamics following Acute Ischaemic Stroke: Effects of Stroke Severity and Stroke Subtype
Conclusions: AIS patients with different OCSP subtypes and severity have homogeneity in CA capability. Cerebral haemodynamic measurements in the UH were distinguishable between stroke subtype and severity, including the association between deteriorating ARI in UH with stroke severity. More studies are needed to determine their clinical significance and to understand the determinants of CA impairment in AIS patients.Cerebrovasc Dis Extra 2018;8:80 –89 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - July 11, 2018 Category: Neurology Source Type: research

Stroke Mortality in Kenya ’s Public Tertiary Hospitals: A Prospective Facility-Based Study
Conclusions: Mortality due to stroke is high, with poor survival observed in the first year after stroke. The risk of death increases with increasing age and duration of hospital stay. There is need for attention to quality of care and long-term needs of stroke patients to mitigate the high mortality rates observed. Public health initiatives aimed at early screening and diagnosis should be enhanced. Further research is recommended to establish the true burden of stroke at the community level to inform appropriate mitigation measures.Cerebrovasc Dis Extra 2018;8:70 –79 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - June 12, 2018 Category: Neurology Source Type: research

Predictors of Cardioembolic Stroke in Japanese Patients with Atrial Fibrillation in the Fushimi AF Registry
Conclusions: In this population-based cohort of Japanese patients with AF, in addition to previous stroke/TIA and older age, sustained AF and low body weight emerged as risk factors for CES, as opposed to any stroke, which may have a different risk profile. Patients with CKD or previous stroke/TIA who developed cardioembolic infarction exhibited more advanced severity. There is a need for direct oral anticoagulants that can be used safely in patients with comorbid AF and CKD.Cerebrovasc Dis Extra 2018;8:50 –59 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - May 30, 2018 Category: Neurology Source Type: research

Knowledge about Stroke in Belo Horizonte, Brazil: A Community-Based Study Using an Innovative Video Approach
Conclusion: Female sex and a family history of stroke increased the odds of recognizing the signs of stroke. Knowledge about the clinical manifestations, risk factors, and management of stroke was low in the studied population.Cerebrovasc Dis Extra 2018;8:60 –69 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - May 30, 2018 Category: Neurology Source Type: research

Spotty Carotid Plaques Are Associated with Inflammation and the Occurrence of Cerebrovascular Symptoms
Conclusions: The present study supports the concept that spottiness is a feature of the carotid plaques rich in inflammation and can be associated with the typical phenotype of high-risk plaques.Cerebrovasc Dis Extra 2018;8:16 –25 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - January 15, 2018 Category: Neurology Source Type: research

Intracranial Arterial Calcification in Black Africans with Acute Ischaemic Stroke
Conclusions: The burden of IAC is very high among native African patients with AIS and preferentially involves proximal inflow arteries. Therefore, the role of large vessel atherosclerosis in ischaemic stroke in native Africans should be explored in future multinational, multimodality studies.Cerebrovasc Dis Extra 2018;8:26 –38 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - January 15, 2018 Category: Neurology Source Type: research

Erythrocyte-Rich Thrombus Is Associated with Reduced Number of Maneuvers and Procedure Time in Patients with Acute Ischemic Stroke Undergoing Mechanical Thrombectomy
Conclusions: In this study, erythrocyte-rich thrombus was associated with noncardioembolic etiology, higher thrombus density, and reduced procedure time.Cerebrovasc Dis Extra 2018;8:39 –49 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - January 15, 2018 Category: Neurology Source Type: research

Oral Health and Brain Injury: Causal or Casual Relation?
Conclusions: Overall, oral health and stroke were related. Periodontitis and tooth loss were independently associated with stroke. However, prevention and timely intervention may reduce the risk of stroke. Stroke was the main cerebral lesion studied in the literature, with almost no publications on other brain lesions.Cerebrovasc Dis Extra 2018;8:1 –15 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - January 10, 2018 Category: Neurology Source Type: research

Frequency, Aetiology, and Outcome of Small Cerebellar Infarction
Conclusions: Small cerebellar infarction accounted for one-third of the ischaemic strokes in this location, most often involved the posterior lobe, causing fewer clinical features, and had a better clinical outcome than large cerebellar infarction. Patients with small cerebellar infarction require appropriate vascular management including investigation for a cardioembolic source.Cerebrovasc Dis Extra 2017;7:173 –180 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - November 2, 2017 Category: Neurology Source Type: research

Blunt Traumatic Extracranial Cerebrovascular Injury and Ischemic Stroke
Background: Ischemic stroke occurs in a significant subset of patients with blunt traumatic cerebrovascular injury (TCVI). The patients are victims of motor vehicle crashes, assaults or other high-energy collisions, and suffer ischemic stroke due to injury to the extracranial carotid or vertebral arteries.Summary: An increasing number of patients with TCVI are being identified, largely because of the expanding use of computed tomography angiography for screening patients with blunt trauma. Patients with TCVI are particularly challenging to manage because they often suffer polytrauma, that is, numerous additional injuries i...
Source: Cerebrovascular Diseases Extra - October 25, 2017 Category: Neurology Source Type: research

Factor XII as a Risk Marker for Hemorrhagic Stroke: A Prospective Cohort Study
Conclusion: We found an independent association between FXII levels and the risk of hemorrhagic stroke, but not between FXII levels and ischemic stroke or myocardial infarction.Cerebrovasc Dis Extra 2017;7:84 –94 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 25, 2017 Category: Neurology Source Type: research

Outcomes of Endovascular Thrombectomy with and without Thrombolysis for Acute Large Artery Ischaemic Stroke at a Tertiary Stroke Centre
Conclusion: Our study highlights the relatively large proportion of patients suitable for EVT who have a contraindication to alteplase and raises the hypothesis that adding alteplase to successful EVT may not be necessary to optimize functional outcome. The results are consistent with observational data from other endovascular centres and support a randomised controlled trial of EVT versus EVT with bridging alteplase.Cerebrovasc Dis Extra 2017;7:95 –102 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 25, 2017 Category: Neurology Source Type: research

Dosage Calculation for Intravenous Thrombolysis of Ischemic Stroke: To Weigh or to Estimate
Conclusion: This first prospective study of weight assessment in acute stroke shows that the use of an easily accessible scale makes it feasible to weigh patients with acute stroke without the treatment delay associated with additional patient transfers. Physicians ’ estimates of patients’ weights demonstrated substantial aberrations from measured weights. Avoiding these deviations would improve the accuracy of tPA dosage.Cerebrovasc Dis Extra 2017;7:103 –110 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 25, 2017 Category: Neurology Source Type: research

In Potential Stroke Patients on Warfarin, the International Normalized Ratio Predicts Ischemia
Conclusions: Sub-therapeutic INR and atrial fibrillation are strongly associated with ischemia in patients on warfarin presenting with acute neurologic symptoms. Ischemia is far less likely in patients with an INR of ≥2 and rare in those with an INR ≥3.6. This study shows that the INR value of a patient on warfarin can help stratify patients’ risk for acute ischemic stroke and guide further neurologic imaging and workup.Cerebrovasc Dis Extra 2017;7:111 –119 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 25, 2017 Category: Neurology Source Type: research

Abbreviation of the Follow-Up NIH Stroke Scale Using Factor Analysis
Conclusions: At 24 h following ischemic stroke, aphasia, neglect, and arm weakness are the most prognostically relevant neurologic findings. The aNIHSS appears to have excellent prognostic accuracy with higher reliability and may be clinically useful.Cerebrovasc Dis Extra 2017;7:120 –129 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 25, 2017 Category: Neurology Source Type: research

Pharyngolaryngeal Sensory Deficits in Patients with Middle Cerebral Artery Infarction: Lateralization and Relation to Overall Dysphagia Severity
Conclusions: This study provides evidence that an intact sensory feedback is of utmost importance to perform nonimpaired swallowing and highlights the key role of disturbed pharyngeal and laryngeal afferents in the pathophysiology of PSD.Cerebrovasc Dis Extra 2017;7:130 –139 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 25, 2017 Category: Neurology Source Type: research

The Missing Link in the Pathophysiology of Vascular Cognitive Impairment: Design of the Heart-Brain Study
Conclusions: The Heart-Brain Study investigates relationships between (cardio-)vascular factors, the hemodynamic status of the heart and the brain, and cognitive impairment. By studying the complete heart-brain axis in patient groups that represent components of this axis, we have the opportunity to assess a combination of clinical and subclinical manifestations of disorders of the heart, vascular system and brain, with hemodynamic status as a possible binding factor.Cerebrovasc Dis Extra 2017;7:140 –152 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 25, 2017 Category: Neurology Source Type: research

Improvement and Aggravation of Spontaneous Unruptured Vertebral Artery Dissection
Conclusions: VAD improvement primarily occurs within 6 months after onset, and VAD aggravation within 1 month. It seems that older patients and current smoking are negative predictors of VAD improvement as risk factors, and as image findings, the pearl and string sign is a positive predictor and occlusion a negative predictor.Cerebrovasc Dis Extra 2017;7:153 –164 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 25, 2017 Category: Neurology Source Type: research

Characteristics and Outcomes of Vertebrobasilar Artery Dissection with Accompanied Atherosclerosis
Conclusion: VBD-related PCS with and without accompanied atherosclerosis had different manifestations and should be regarded as distinct arterial diseases.Cerebrovasc Dis Extra 2017;7:165 –172 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 25, 2017 Category: Neurology Source Type: research

Improvement and Aggravation of Spontaneous Unruptured Vertebral Artery Dissection
Conclusions: VAD improvement primarily occurs within 6 months after onset, and VAD aggravation within 1 month. It seems that older patients and current smoking are negative predictors of VAD improvement as risk factors, and as image findings, the pearl and string sign is a positive predictor and occlusion a negative predictor.Cerebrovasc Dis Extra 2017;7:153 –164 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 17, 2017 Category: Neurology Source Type: research

Characteristics and Outcomes of Vertebrobasilar Artery Dissection with Accompanied Atherosclerosis
Conclusion: VBD-related PCS with and without accompanied atherosclerosis had different manifestations and should be regarded as distinct arterial diseases.Cerebrovasc Dis Extra 2017;7:165 –172 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 17, 2017 Category: Neurology Source Type: research

The Missing Link in the Pathophysiology of Vascular Cognitive Impairment: Design of the Heart-Brain Study
Conclusions: The Heart-Brain Study investigates relationships between (cardio-)vascular factors, the hemodynamic status of the heart and the brain, and cognitive impairment. By studying the complete heart-brain axis in patient groups that represent components of this axis, we have the opportunity to assess a combination of clinical and subclinical manifestations of disorders of the heart, vascular system and brain, with hemodynamic status as a possible binding factor.Cerebrovasc Dis Extra 2017;7:140 –152 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 10, 2017 Category: Neurology Source Type: research

Pharyngolaryngeal Sensory Deficits in Patients with Middle Cerebral Artery Infarction: Lateralization and Relation to Overall Dysphagia Severity
Conclusions: This study provides evidence that an intact sensory feedback is of utmost importance to perform nonimpaired swallowing and highlights the key role of disturbed pharyngeal and laryngeal afferents in the pathophysiology of PSD.Cerebrovasc Dis Extra 2017;7:130 –139 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 3, 2017 Category: Neurology Source Type: research

Abbreviation of the Follow-Up NIH Stroke Scale Using Factor Analysis
Conclusions: At 24 h following ischemic stroke, aphasia, neglect, and arm weakness are the most prognostically relevant neurologic findings. The aNIHSS appears to have excellent prognostic accuracy with higher reliability and may be clinically useful.Cerebrovasc Dis Extra 2017;7:120 –129 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 2, 2017 Category: Neurology Source Type: research

In Potential Stroke Patients on Warfarin, the International Normalized Ratio Predicts Ischemia
Conclusions: Sub-therapeutic INR and atrial fibrillation are strongly associated with ischemia in patients on warfarin presenting with acute neurologic symptoms. Ischemia is far less likely in patients with an INR of ≥2 and rare in those with an INR ≥3.6. This study shows that the INR value of a patient on warfarin can help stratify patients’ risk for acute ischemic stroke and guide further neurologic imaging and workup.Cerebrovasc Dis Extra 2017;7:111 –119 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - August 11, 2017 Category: Neurology Source Type: research

Dosage Calculation for Intravenous Thrombolysis of Ischemic Stroke: To Weigh or to Estimate
Conclusion: This first prospective study of weight assessment in acute stroke shows that the use of an easily accessible scale makes it feasible to weigh patients with acute stroke without the treatment delay associated with additional patient transfers. Physicians ’ estimates of patients’ weights demonstrated substantial aberrations from measured weights. Avoiding these deviations would improve the accuracy of tPA dosage.Cerebrovasc Dis Extra 2017;7:103 –110 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - June 9, 2017 Category: Neurology Source Type: research

Dosage Calculation for Intravenous Thrombolysis of Ischemic Stroke: To Weigh or to Estimate?
Conclusion: This first prospective study of weight assessment in acute stroke shows that the use of an easily accessible scale makes it feasible to weigh patients with acute stroke without the treatment delay associated with additional patient transfers. Physicians ’ estimates of patients’ weights demonstrated substantial aberrations from measured weights. Avoiding these deviations would improve the accuracy of tPA dosage.Cerebrovasc Dis Extra 2017;7:103 –110 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - May 31, 2017 Category: Neurology Source Type: research

Outcomes of Endovascular Thrombectomy with and without Thrombolysis for Acute Large Artery Ischaemic Stroke at a Tertiary Stroke Centre
Conclusion: Our study highlights the relatively large proportion of patients suitable for EVT who have a contraindication to alteplase and raises the hypothesis that adding alteplase to successful EVT may not be necessary to optimize functional outcome. The results are consistent with observational data from other endovascular centres and support a randomised controlled trial of EVT versus EVT with bridging alteplase.Cerebrovasc Dis Extra 2017;7:95 –102 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - May 2, 2017 Category: Neurology Source Type: research

Factor XII as a Risk Marker for Hemorrhagic Stroke: A Prospective Cohort Study
Conclusion: We found an independent association between FXII levels and the risk of hemorrhagic stroke, but not between FXII levels and ischemic stroke or myocardial infarction.Cerebrovasc Dis Extra 2017;7:84 –94 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - April 21, 2017 Category: Neurology Source Type: research

Blunt Traumatic Extracranial Cerebrovascular Injury and Ischemic Stroke
Background: Ischemic stroke occurs in a significant subset of patients with blunt traumatic cerebrovascular injury (TCVI). The patients are victims of motor vehicle crashes, assaults or other high-energy collisions, and suffer ischemic stroke due to injury to the extracranial carotid or vertebral arteries.Summary: An increasing number of patients with TCVI are being identified, largely because of the expanding use of computed tomography angiography for screening patients with blunt trauma. Patients with TCVI are particularly challenging to manage because they often suffer polytrauma, that is, numerous additional injuries i...
Source: Cerebrovascular Diseases Extra - April 11, 2017 Category: Neurology Source Type: research

Volume and Characteristics of Intracerebral Hemorrhage with Direct Oral Anticoagulants in Comparison with Warfarin 

Conclusions: Based on the results of the present study, in terms of the risks associated with ICHs, the use of DOACs appears to be safer than warfarin for anticoagulation therapy. Further studies are required to validate these findings. 
Cerebrovasc Dis Extra 2017;7:62 –71 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - April 3, 2017 Category: Neurology Source Type: research

High Risk of Seizures and Epilepsy after Decompressive Hemicraniectomy for Malignant Middle Cerebral Artery Stroke 

Conclusion: The incidence of seizures and epilepsy after malignant MCA infarcts submitted to DHC might be very high. Seizure might occur precociously in patients who are not submitted to anticonvulsant prophylaxis. The large stroke volume and the large cortical ischemic area seem to be the main risk factors for seizure or epilepsy development in this subtype of stroke. 
Cerebrovasc Dis Extra 2017;7:51 –61 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - March 30, 2017 Category: Neurology Source Type: research

Measurement of Oxygen Desaturation Is Not Useful for the Detection of Aspiration in Dysphagic Stroke Patients
Conclusions: According to this study, measurement of oxygen desaturation is not a suitable screening tool for the detection of aspiration in stroke patients.Cerebrovasc Dis Extra 2017;7:44-50 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - March 3, 2017 Category: Neurology Source Type: research

Brain Natriuretic Peptide Is a Powerful Predictor of Outcome in Stroke Patients with Atrial Fibrillation 

Conclusions: Apart from NIHSS score, BNP was a very useful predictor for long-term outcomes of patients with NVAF after AIS. 
Cerebrovasc Dis Extra 2017;7:35 –43 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - March 2, 2017 Category: Neurology Source Type: research

MRI-Based Neuroanatomical Predictors of Dysphagia, Dysarthria, and Aphasia in Patients with First Acute Ischemic Stroke 

Conclusion: Predicting outcomes following acute stroke is important for treatment decisions. Determining the risk of major post-stroke impairments requires consideration of factors beyond lesion localization. Accordingly, we demonstrated interactions between localized and global brain function for dysphagia and elucidated common lesion locations across 3 debilitating impairments. 
Cerebrovasc Dis Extra 2017;7:21 –34 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - February 16, 2017 Category: Neurology Source Type: research

The Course and Impact of Poststroke Insomnia in Stroke Survivors Aged 18 to 65 Years: Results from the Psychosocial Outcomes In StrokE (POISE) Study 

Conclusions: Chronic insomnia has a negative effect on disability and return to work 1 year after stroke even after adjusting for demographic, psychiatric, and disability factors. Identifying and appropriately targeting insomnia through known effective treatments may improve functional outcomes after stroke. 
Cerebrovasc Dis Extra 2017;7:9 –20 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - February 3, 2017 Category: Neurology Source Type: research

The Role of White Matter Damage in the Risk of Periprocedural Diffusion-Weighted Lesions after Carotid Artery Stenting
Conclusions: Treated side and preexisting white matter damage are risk conditions for brain microembolism during CAS. This should be taken into account to optimize severe carotid artery disease management.Cerebrovasc Dis Extra 2017;7:1-8 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - January 26, 2017 Category: Neurology Source Type: research

Low Incidence of Atrial Fibrillation in Patients with Transient Ischemic Attack
Conclusion: In this retrospective study, patients with TIA had a low incidence of AF detected with ECG and 72-hour Holter monitoring. Prospective studies are needed to confirm these findings.Cerebrovasc Dis Extra 2016;6:140-149 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - November 29, 2016 Category: Neurology Source Type: research

Risk Factors for Incident Carotid Artery Revascularization among Older Adults: The Cardiovascular Health Study
Conclusions: Even after accounting for carotid stenosis and incident cerebral ischemic events, carotid revascularization is related to age, gender, and cardiovascular risk factors. Further study of these demographic disparities and the role of risk factor control is warranted.Cerebrovasc Dis Extra 2016;6:129-139 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - November 15, 2016 Category: Neurology Source Type: research

How Reliable Are Administrative Data for Capturing Stroke Patients and Their Care
Conclusions: Inpatient and ED administrative data were found to be reliable in the reporting of the International Classification of Diagnosis, 10th revision, Canada (ICD-10-CA)-coded ischemic stroke, ICH and TIA, and for the recording of atrial fibrillation and diabetes. The combination of physician billing data with hospital administrative data greatly improved the capture of some diagnostic services provided to inpatients.Cerebrovasc Dis Extra 2016;6:96-106 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 18, 2016 Category: Neurology Source Type: research