Individual versus task differences in slow potential generators
AbstractAverage slow potentials (SPs) can be computed from any voluntary task, minimally involving attention to anticipated stimuli. Their topography when recorded by large electrode arrays even during simple tasks is complex, multifocal, and its generators appear to be equally multifocal and highly variable across subjects. Various sources of noise of course contaminate such averages and must contribute to the topographic complexity. Here, we report a study in which the non-averaged SP band (0 to 1  Hz) was analyzed by independent components (ICA), from 256 channel recordings of 18 subjects, during four task conditio...
Source: Neurological Sciences - January 16, 2021 Category: Neurology Source Type: research

Cyclophosphamide treatment in active multiple sclerosis
ConclusionsCYC continues to be a valid therapeutic option, especially in regions with limited access to high-efficiency therapies particularly in patients with high relapsing activity and malignant course. (Source: Neurological Sciences)
Source: Neurological Sciences - January 16, 2021 Category: Neurology Source Type: research

Update on therapy of chronic immune-mediated neuropathies
AbstractChronic immune-mediated neuropathies, including chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), neuropathies associated with monoclonal gammopathy, and multifocal motor neuropathy (MMN), are a group of disorders deemed to be caused by an immune response against peripheral nerve antigens. Several immune therapies have been reported to be variably effective in these neuropathies including steroids, plasma exchange, and high-dose intravenous (IVIg) or subcutaneous (SCIg) immunoglobulins. These therapies are however far from being invariably effective and may be associated with a number of side effect...
Source: Neurological Sciences - January 16, 2021 Category: Neurology Source Type: research

Identification of hsa-miR-106a-5p as an impact agent on promotion of multiple sclerosis using multi-step data analysis
AbstractMultiple sclerosis (MS) is a chronic, demyelinating disease in which the neuron myelin sheath is disrupted and leading to signal transductions disabilities. The evidence demonstrated that gene expression patterns and their related regulating factors are the most critical agents in MS demyelinating process. A miRNA is a small non-coding RNA which functions in post-transcriptional regulation of gene expression. Identification of specific miRNA dysregulation patterns in MS blood samples compared to healthy control can be used as a diagnostic and prognostic agent. Through the literature review and bioinformatics analys...
Source: Neurological Sciences - January 16, 2021 Category: Neurology Source Type: research

Spontaneous upbeat contratorsional nystagmus with downbeat ipsitorsional nystagmus during horizontal gaze in chronic lateral medullary infarction
(Source: Neurological Sciences)
Source: Neurological Sciences - January 16, 2021 Category: Neurology Source Type: research

SLC20A2 mutation manifesting as very late-onset orofacial dyskinesia
(Source: Neurological Sciences)
Source: Neurological Sciences - January 16, 2021 Category: Neurology Source Type: research

Effect of the COVID-19 pandemic and the lockdown measures on the local stroke network
DiscussionOur observational study, involving hub-and-spoke stroke network of a wide regional area, indicates that the COVID-19 outbreak impacted on the acute stroke management. This impact was equally observed in hub as well as in spoke centers. (Source: Neurological Sciences)
Source: Neurological Sciences - January 15, 2021 Category: Neurology Source Type: research

Propofol shows less negative effects on cognitive performances than dexmedetomidine in elderly intensive care unit patients
ConclusionOur study compared the effects of commonly used medications on short-term cognitive impairment in elderly ICU patients, which would aid the selection of sedation plan for the benefit of ICU patients. (Source: Neurological Sciences)
Source: Neurological Sciences - January 15, 2021 Category: Neurology Source Type: research

Message from the Editor-in-Chief
(Source: Neurological Sciences)
Source: Neurological Sciences - January 15, 2021 Category: Neurology Source Type: research

Epilepsy and quality of life: what does really matter?
ConclusionQuality of life in adult PWE is predominantly affected by psychosocial factors more than epilepsy-related ones. These findings suggest that effective epilepsy management requires more than seizure control, and early detection of psychological dysfunction and tailored interventions to improve the QoL should be considered. (Source: Neurological Sciences)
Source: Neurological Sciences - January 15, 2021 Category: Neurology Source Type: research

Neuroanatomical changes in early Parkinson ’s disease with mild cognitive impairment: a VBM study; the Parkinson’s Disease Cognitive Impairment Study (PaCoS)
AbstractIntroductionMild cognitive impairment (MCI) is common in Parkinson ’s disease (PD), but the underlying pathological mechanism has not been fully understood. Voxel-based morphometry could be used to evaluate regional atrophy and its relationship with cognitive performances in early PD-MCI.Patients and MethodsOne hundred and six patients with PD were recruited from a larger cohort of patients, the Parkinson ’s Disease Cognitive Impairment Study (PaCoS). Subject underwent a T1-3D MRI and a complete clinical and neuropsychological evaluation. Patients were divided into PD with normal cognition (PD-NC) and P...
Source: Neurological Sciences - January 14, 2021 Category: Neurology Source Type: research

Multidisciplinary care in Amyotrophic Lateral Sclerosis: a systematic review and meta-analysis
AbstractMultidisciplinary care (MDC) has been the most recommended approach for symptom management in amyotrophic lateral sclerosis (ALS) but there is conflicting evidence about its effectiveness on survival and quality of life (QoL) of ALS patients. We conducted a systematic review to determine the effects of multidisciplinary care compared to general neurological care in survival and quality of life of ALS patients. A comprehensive literature search using Scopus, MEDLINE-PubMed, Cochrane, Web of Science, PEDro, and Science Direct was undertaken. Studies related to multidisciplinary care or general neurological care in AL...
Source: Neurological Sciences - January 14, 2021 Category: Neurology Source Type: research

Prevalence and predictors of atrial fibrillation in patients with embolic stroke of undetermined source: a real-life single-center retrospective study
AbstractIntroductionUp to one-third of ischemic strokes remained cryptogenic despite extensive investigations. Atrial fibrillation may be detected in a significant proportion of patients with embolic stroke of undetermined source, particularly after the introduction of implantable loop recorder in clinical practice.MethodsWe retrospectively included all the consecutive patients with embolic stroke of undetermined source referred to our units in the period November 2013 to December 2018 and in which an implantable loop recorder was positioned within 6  months from stroke event. Prevalence and predictors of atrial fibri...
Source: Neurological Sciences - January 14, 2021 Category: Neurology Source Type: research

Cardiovascular fingolimod effects on rapid baroreceptor unloading are counterbalanced by baroreflex resetting
This study evaluated cardiovascular responses to Valsalva maneuver (VM)-induced baroreceptor unloading and loading upon fingolimod initiation.Patients and methodsTwenty-one patients with relapsing-remitting multiple sclerosis performed VMs before and 0.5, 1, 2, 3, 4, 5, and 6  hours after fingolimod initiation. We recorded heart rate (HR) as RR intervals (RRI), systolic and diastolic BP (BPsys, BPdia) during VM phase 1, VM phase 2 early, VM phase 2 late, and VM phase 4. Using linear regression analysis between decreasing BPsys and RRI values during VM phase 2 early, we determined baroreflex gain (BRG) reflecting vagal...
Source: Neurological Sciences - January 14, 2021 Category: Neurology Source Type: research

COVID-19 impact on neurology training program in Italy
AbstractThe ongoing COVID-19 pandemic is having a huge impact on clinical activity of all hospitals, including the ones involved in training of residents. In addition, neurology residents underwent substantial modifications of their training program. Aim of our investigation was to evaluate the impact of COVID-19 pandemic on the educational activities of Italian neurology residents through an online questionnaire delivered to neurology residents. The results obtained showed that almost 30% of the respondents were redistributed to COVID-19 units. Neurology departments underwent substantial modifications of their organizatio...
Source: Neurological Sciences - January 14, 2021 Category: Neurology Source Type: research

A scoping review of the nature of physiotherapists ’ role to avoid fall in people with Parkinsonism
ConclusionPhysiotherapy has the possibility to decrease fall incidence and fall risk in people with PD. However, the heterogeneity in the patients ’ selection, intervention studies, outcome measures chosen, time since the onset of disease, variation in intensity, and duration of treatment between included studies make the comparisons difficult. Consequently, more studies are needed on best intervention. (Source: Neurological Sciences)
Source: Neurological Sciences - January 14, 2021 Category: Neurology Source Type: research

A novel Q93H missense mutation in DCTN1 caused distal hereditary motor neuropathy type 7B and Perry syndrome from a Chinese family
AbstractTheDynactin 1 (DCTN1) encodes the p150 subunit of dynactin, which engages retrograde axonal transport. Missense mutations inDCTN1 have been linked to a series of neurodegenerative diseases, including distal hereditary motor neuropathies (dHMN) and Perry syndrome. A few pathogenicDCTN1 mutations related with Perry syndrome have been described within, or adjacent to, the highly conserved N-terminal cytoskeleton-associated protein, glycine-rich (CAP-Gly) domain. But to our best knowledge, only the pathogenic G59S mutation inDCTN1 has been reported in dHMN7B families. Herein, we provided a novel heterozygous mutation i...
Source: Neurological Sciences - January 14, 2021 Category: Neurology Source Type: research

Clinical features associated with drooling in Parkinson ’s disease
ConclusionDrooling is not caused by a single factor; it is influenced and related to several clinical features. Some clinical factors participate in the onset of drooling while others are concomitant. (Source: Neurological Sciences)
Source: Neurological Sciences - January 14, 2021 Category: Neurology Source Type: research

Evaluation of clinical findings and neurofibromatosis type 1 bright objects on brain magnetic resonance images of 60 Turkish patients with NF1 gene variants
AbstractNeurofibromatosis type 1 (NF1) is caused by mutations in theNF1 gene. This retrospective study aims to evaluate the clinical manifestations and brain magnetic resonance images (MRI) analysis in 60 genetically confirmed NF1 patients. The results of next-generation sequencing (NGS), Sanger sequencing, and MLPA ofNF1 gene were evaluated. A total of 54 different variants were identified. Fourteen out of them were novel variants (25.9%). Patients who complied with NIH criteria had most frequently frameshift variants (11/32 patients), and those with only CALMs had missense variants (9/28 patients). Neurofibromatosis type...
Source: Neurological Sciences - January 14, 2021 Category: Neurology Source Type: research

The predictive value of platelet to lymphocyte ratio and D-dimer to fibrinogen ratio combined with WELLS score on lower extremity deep vein thrombosis in young patients with cerebral hemorrhage
ConclusionsPLR and DFR combined with Wells score have high specificity for predicting LEDVT in YCH patients with low missed diagnosis and low misdiagnosis rates. They are worthy of popularization and application. (Source: Neurological Sciences)
Source: Neurological Sciences - January 14, 2021 Category: Neurology Source Type: research

Predictors of self-perceived health worsening over COVID-19 emergency in ALS
DiscussionCOVID-19 emergency and its management exerted a significant impact on self-perceived health status in patients with ALS, particularly in those cases in the earliest disease phases and with a more aggressive disease course. These findings have potential to improve personalized medicine strategies in the next phase. (Source: Neurological Sciences)
Source: Neurological Sciences - January 14, 2021 Category: Neurology Source Type: research

Study on different pathogenic factors in different disease stages of patients with Wilson disease
ConclusionThere are different pathogenic factors in different stages of WD. At the neuronal necrosis stage, copper deposition was decreased in WD patients. In the stage of fiber injury and neuronal necrosis, there is oxidative stress injury in WD patients. In the neuronal necrosis phase, WD patients have an inflammatory response. (Source: Neurological Sciences)
Source: Neurological Sciences - January 14, 2021 Category: Neurology Source Type: research

Movement disorders in primary central nervous system lymphoma: two unreported cases and a review of literature
ConclusionsThis study identified those features of PCNSL-related MDs that could support an appropriate approach to such a rare condition. In fact, while the outcome remains still poor, the therapeutic scenario of PCNSL is changing; an early diagnosis together with an adequate management will be thus crucial for timely and successful interventions. (Source: Neurological Sciences)
Source: Neurological Sciences - January 14, 2021 Category: Neurology Source Type: research

The impact of lockdown during SARS-CoV-2 outbreak on behavioral and psychological symptoms of dementia
ConclusionThis is one of the first studies to investigate the presence of BPSD during SARS-CoV-2 outbreak and related nationwide lockdown, showing only slight, likely not clinically relevant, differences in BPSD burden, concerning mostly agitation and aggression, anxiety, apathy and indifference, and irritability. (Source: Neurological Sciences)
Source: Neurological Sciences - January 14, 2021 Category: Neurology Source Type: research

Effect of pyridoxine plus pyridostigmine treatment on vincristine-induced peripheral neuropathy in pediatric patients with acute lymphoblastic leukemia: a single-center experience
ConclusionThe WHO and NCI CTCAE scorings may be used for evaluating neuropathy at diagnosis and follow-up of neurotoxicity with treatment. Pyridoxine plus pyridostigmine therapy may be an effective option in the treatment of VIPN. (Source: Neurological Sciences)
Source: Neurological Sciences - January 13, 2021 Category: Neurology Source Type: research

A new and short protocol to achieve the early diagnosis of mild cognitive impairment
ConclusionsA proper selection of cognitive measures within those included in the already-available neuropsychological batteries may provide a thorough assessment of MCI and allow its timely diagnosis. (Source: Neurological Sciences)
Source: Neurological Sciences - January 13, 2021 Category: Neurology Source Type: research

Epilepsy, status epilepticus, and hemiplegic migraine coexisting with a novel SLC4A4 mutation
ConclusionThese results expand the clinical and mutational spectra ofSLC4A4-related disease and have implications for understanding the potential role of NBCe1 in the pathophysiologic processes of hemiplegic migraine and epilepsy/status epilepticus associated with the mutation. (Source: Neurological Sciences)
Source: Neurological Sciences - January 13, 2021 Category: Neurology Source Type: research

Favourable course in a cohort of Parkinson ’s disease patients infected by SARS-CoV-2: a single-centre experience
AbstractThe COVID-19 outbreak has had a dramatic impact on the healthcare system due to the rapid, worldwide spread of the virus, highlighting several considerations on the best management of infected patients and also potential risks and prognostic factors in patients with pre-existing chronic diseases exposed to the virus. Neurodegenerative disorders are known to be chronic, disabling diseases that imply a higher vulnerability to infections, and for this reason, it has been suggested that SARS-CoV-2 infection may have a worse course in these patients. In the present study, we report our experience with 12 patients affect...
Source: Neurological Sciences - January 13, 2021 Category: Neurology Source Type: research

Brain function during central fatigue induced by intermittent high-intensity cycling
ConclusionHigher, relative intensities (10 and 20 °) increased brain function, regardless of fatigue occurrence. HIIT (high-intensity interval training) led to an alteration in the neural response. Further work investigating the usefulness of HIIT to improve brain function is warranted. (Source: Neurological Sciences)
Source: Neurological Sciences - January 13, 2021 Category: Neurology Source Type: research

Cluster headache, beyond the pain: a comparative cross-sectional study
AbstractObjectiveTo compare the presence of allodynia, pain catastrophizing, and the impact of headaches on patients with cluster headache (CH) and healthy individuals. Our second aim was to analyze the relationship between catastrophism, psychological comorbidities, and the impact in CH.MethodsWe designed this cross-sectional study to compare various factors among 47 patients diagnosed with CH and 40 healthy controls, and then focus on catastrophism, anxiety, depression, and impact in the CH group.ResultsThere were statistically significant differences between CH and the asymptomatic group in Allodynia Symptom Checklist (ASC) (p
Source: Neurological Sciences - January 13, 2021 Category: Neurology Source Type: research

Diabetes and impaired fasting glucose in a population-based sample of individuals aged 75  + years: associations with cognition, major depressive disorder, functionality and quality of life—the Pietà study
ConclusionsIFG and DM were common in this population-based sample aged 75  + years old, as were inadequate diagnoses and treatments of DM. DM individuals presented poor performance in the executive function test, functionality, and QoL. Further studies are recommended to investigate the value of an IFG diagnosis among the most elderly population. (Source: Neurological Sciences)
Source: Neurological Sciences - January 13, 2021 Category: Neurology Source Type: research

Hereditary spastic paraplegia
AbstractHereditary spastic paraplegias (HSPs) are a group of neurodegenerative disorders which involve the corticospinal tracts and present with distinct spasticity and weakness of the lower extremities. The estimated prevalence of HSP is around 1.8/100,000 cases for both autosomal dominant and autosomal recessive types. Classification of HSP is based on inheritance pattern, clinical phenotype, and molecular pathophysiological mechanisms. The most common neuropathological sign is the axonal degeneration involving the lateral corticospinal tracts in both the cervical and thoracic spinal cord. The target of this review artic...
Source: Neurological Sciences - January 13, 2021 Category: Neurology Source Type: research

Pegylated interferon beta-1a (Plegridy) Italian real-world experience: a Delphi analysis of injection-site reaction and flu-like symptom management
ConclusionsPatient education and counseling play a key role in promoting adherence to treatment especially in the first months also in patients switching from nonpegylated IFNs to peginterferon beta-1a. (Source: Neurological Sciences)
Source: Neurological Sciences - January 13, 2021 Category: Neurology Source Type: research

Novel compound heterozygous variants in the GFPT1 gene leading to rare limb-girdle congenital myasthenic syndrome with rimmed vacuoles
Conclusions: Collectively, molecular genetic analysis and muscle biopsy play crucial roles in the diagnosis of GFPT1-related LG-CMS with rimmed vacuoles (a rare phenotype of CMS) and have important implications for treatment decision. (Source: Neurological Sciences)
Source: Neurological Sciences - January 13, 2021 Category: Neurology Source Type: research

Retinal nerve fiber layer changes in migraine: a systematic review and meta-analysis
ConclusionsThe findings from our comprehensive meta-analysis with large datasets strengthen the clinical evidence of the RNFL thickness reduction in migraine. RNFL thickness via spectral-domain OCT measurement demonstrates the potential role in differentiating patients with migraine, especially migraine with aura, from healthy controls. (Source: Neurological Sciences)
Source: Neurological Sciences - January 13, 2021 Category: Neurology Source Type: research

Statin use and Parkinson ’s disease incidence
(Source: Neurological Sciences)
Source: Neurological Sciences - January 13, 2021 Category: Neurology Source Type: research

AChRAb and MuSKAb double-seropositive myasthenia gravis: a distinct subtype?
This study investigated the characteristics of double-seropositive myasthenia gravis (DSP-MG) in southern China for disease subtype classification.MethodsA case-control study was carried out in which the characteristics of DSP-MG patients (n = 17) were compared to those of muscle-specific tyrosine kinase antibody-positive (MuSK)-MG and acetylcholine receptor antibody-positive (AChR)-MG patients (n = 8 and 27, respectively). We also performed a literature review of DSP-MG patients.ResultsCompared to AChR-MG, DSP-MG had greater bulbar dysfunction (47.1% vs 18.6%,P = 0.04), higher incidence...
Source: Neurological Sciences - January 12, 2021 Category: Neurology Source Type: research

Lynch syndrome-associated repeated stroke with MLH1 frame-shift mutation
We describe the case of a 34-year-old female patient with 50  days of sudden dizziness and left limb weakness, whose head CT scan showed large infarction in the right frontal temporal parietal lobe and basal ganglia area. Imaging examinations and pathological biopsy indicated high-grade serous carcinoma (HGSC) IIIA1 of the right ovary. In addition, a novel f rame-shift mutation in the MLH1 gene (c.1621dupG, p.A541Gfs*16) was found in the genetic panel sequence. It may render declining of MLH1 protein and also associate with the patient’s progressive clinical manifestations of multiple systems. Therefore, the tim...
Source: Neurological Sciences - January 12, 2021 Category: Neurology Source Type: research

The impact of the COVID-19 pandemic on people with neurological disorders: an urgent need to enhance the health care system ’s preparedness
(Source: Neurological Sciences)
Source: Neurological Sciences - January 12, 2021 Category: Neurology Source Type: research

Stroke and digital technology: a wake-up call from COVID-19 pandemic
ConclusionThe global emergency represented by the COVID-19 pandemic can be the stimulus to accelerate the digitalization process in the field of stroke for the use of new methods on a large scale. (Source: Neurological Sciences)
Source: Neurological Sciences - January 12, 2021 Category: Neurology Source Type: research

Association between tumor necrosis factor alpha and lymphotoxin alpha gene polymorphisms and migraine occurrence among Jordanians
In this study, polymorphisms in tumor necrosis factor alpha (TNF α) and lymphotoxin alpha (LTA) genes were tested for association with migraine. A total of 398 participants (198 migraine patients and 200 controls) were recruited in the study. Serum TNF level was measured using a sandwich ELISA kit. Lymphocytes ’ and monocytes’ counts were obtained from a differential complete blood count profile. Participants’ DNA was extracted and genotyped for rs1800629 and rs1799724 inTNF α, and rs909253 inLTA. Controls had a significantly higher mean lymphocyte count (P = 0.018), while the mean monocyte co...
Source: Neurological Sciences - January 12, 2021 Category: Neurology Source Type: research

Antihistamines as a common cause of new-onset seizures: a single-center observational study
ConclusionIn our population, antihistamine accounted for the highest proportion of drug-induced seizures. Considering that antihistamines are widely used as over-the-counter drugs around the world, they should be considered a possible cause of new-onset seizures. (Source: Neurological Sciences)
Source: Neurological Sciences - January 12, 2021 Category: Neurology Source Type: research

Preclinical studies of mesenchymal stem cells transplantation in amyotrophic lateral sclerosis: a systemic review and metaanalysis
ConclusionsThese results showed that MSCs transplantation was beneficial for neurobehavioral improvement in the treatment of ALS animal model and recommended that all potential reparative roles of MSCs postdelivery, should be carefully considered and fused to maximize the effectiveness of MSCs therapy in ALS. (Source: Neurological Sciences)
Source: Neurological Sciences - January 12, 2021 Category: Neurology Source Type: research

Serum B cell lymphoma-2 concentrations and mortality of patients with spontaneous intracerebral hemorrhage
AbstractObjectiveThere is scarce data on B cell lymphoma 2 (Bcl2), a member of the Bcl-2 family of antiapoptotic molecules of the intrinsic apoptosis pathway, in patients with spontaneous intracerebral hemorrhage (SIH). In one study, higher serum Bcl2 levels were found in patients with SIH than in healthy subjects. Thus, the objective of our study was to compare serum Bcl2 levels in surviving and non-surviving SIH patients.MethodsPatients with severe supratentorial SIH (defined as Glasgow Coma Scale  
Source: Neurological Sciences - January 12, 2021 Category: Neurology Source Type: research

Association of dietary diversity score (DDS) and migraine headache severity among women
ConclusionDDS was inversely associated with migraine disability, pain severity, and headache frequency. Additional studies are needed to replicate these findings and to explore mechanisms that mediate the association between DDS and migraine attacks. (Source: Neurological Sciences)
Source: Neurological Sciences - January 11, 2021 Category: Neurology Source Type: research

Epileptic olfactory auras: a clinical spectrum
ConclusionsThe relative frequency of OAs in focal epilepsies is likely to be found higher than expected. Elementary OAs occur much more frequently than complex OAs. Among the elementary OAs, elementary unpleasant OAs and elementary neutral OAs are the most common types, whereas elementary pleasant OAs are extremely rare. (Source: Neurological Sciences)
Source: Neurological Sciences - January 11, 2021 Category: Neurology Source Type: research

Stroke admission rates before, during and after the first phase of the COVID-19 pandemic
AbstractBackgroundThere was a significant decrease in stroke admissions during the first phase of the COVID-19 pandemic. There are concerns that stroke patients have not sought medical attention and in the months after the lockdown suffer recurrent severe strokes. The aims of this study were to investigate how stroke admission rates and distributions of severity varied before, during and after the lockdown in a representative Norwegian hospital population.MethodsAll patients discharged from Akershus University Hospital with a diagnosis of transient ischemic attack (TIA) or acute stroke from January to September 2020 were i...
Source: Neurological Sciences - January 11, 2021 Category: Neurology Source Type: research

Neurological manifestations of coronavirus disease 2019: exploring past to understand present
AbstractSARS-CoV-2 infection, resulting in Coronavirus disease 2019 (COVID-19), has significantly affected the entire world. It was labelled a pandemic by World Health Organization. Although it commonly produces respiratory symptoms, neurological features have been described. Neurological manifestations may vary from non-specific symptoms such as headache, dizziness, myalgia and/or fatigue, olfactory or taste dysfunction to specific syndromes including meningitis, stroke, acute transverse myelitis and Guillain-Barre syndrome. This review describes potential pathogenetic mechanisms and neurological manifestations of COVID-1...
Source: Neurological Sciences - January 11, 2021 Category: Neurology Source Type: research

The vessel density of the superficial retinal capillary plexus as a new biomarker in cerebral small vessel disease: an optical coherence tomography angiography study
ConclusionOCTA revealed a significant decrease in retinal microvascular perfusion in CSVD patients, and retinal hypoperfusion was related to MRI markers and cognitive function, suggesting that these parameters could have potential utility as early disease biomarkers. (Source: Neurological Sciences)
Source: Neurological Sciences - January 11, 2021 Category: Neurology Source Type: research

Acute motor axonal polyneuropathy in one parkinsonian patient receiving moderate dosage of oral levodopa
(Source: Neurological Sciences)
Source: Neurological Sciences - January 11, 2021 Category: Neurology Source Type: research