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Ulnar neuropathy at wrist: entrapment at a very “congested” site
AbstractUlnar tunnel syndrome indicates ulnar neuropathy at different sites within the wrist. Several classifications of ulnar tunnel syndrome are present in literature, based upon typical nerve anatomy. However, anatomical variations are not uncommon and can complicate assessment. The etiology is also complex, due to the numerous potential causes of entrapment. Clinical examination, neurophysiological testing, and imaging are all used to support the diagnosis. At present, many therapeutic approaches are available, ranging from observation to surgical management. Although ulnar neuropathy at the wrist has undergone extensi...
Source: Neurological Sciences - May 19, 2018 Category: Neurology Source Type: research

The relationship with restless legs syndrome, fibromyalgia, and depressive symptoms in migraine patients
ConclusionsIn our study, the greater frequency of restless legs syndrome, depressive symptoms, and fibromyalgia in the patients with migraine supports the role of dopamine, which is common to all three disorders. Interviews focused on these problems among migraine patients may help to decide on the best available treatment modality. (Source: Neurological Sciences)
Source: Neurological Sciences - May 18, 2018 Category: Neurology Source Type: research

Cognitive assessment in multiple sclerosis —an Italian consensus
AbstractThe aim of this consensus paper was to define the state of the art on cognitive assessment of persons with multiple sclerosis (PwMS), with the purpose of providing recommendations for the Italian centers involved in MS management. While there are no formal guidelines published regarding the assessment of cognitive function in MS, on the basis of an expert opinion meeting, held in Milan (Italy) on July 4, 2016, we report the recommendations of a panel of Italian experts including MS neurologists and neuropsychologists for the assessment and follow-up of cognitive function in adult MS subjects. (Source: Neurological Sciences)
Source: Neurological Sciences - May 15, 2018 Category: Neurology Source Type: research

Highlights of Issue 6, 2018
(Source: Neurological Sciences)
Source: Neurological Sciences - May 15, 2018 Category: Neurology Source Type: research

Basal vitamin D levels and disease activity in multiple sclerosis patients treated with fingolimod
AbstractBackgroundSeveral studies have shown an association between 25-hydroxyvitamin D (25[OH]D) levels and multiple sclerosis (MS) susceptibility and/or level of disease activity in patients treated with first line drugs.AimsTo investigate whether baseline 25[OH]D values could influence disease activity also during treatment with the second-line drug fingolimod (FTY).Patients and methodsWe enrolled 176 MS patients who started FTY at the San Raffaele Hospital (OSR) MS center with available 25[OH]D measurement at the time of treatment start. We then prospectively followed them for 2  years with periodic clinical exami...
Source: Neurological Sciences - May 13, 2018 Category: Neurology Source Type: research

Anodal tDCS of the swallowing motor cortex for treatment of dysphagia in multiple sclerosis: a pilot open-label study
In conclusion, our preliminary results show that anodal tDCS has therapeutic potential in the treatment of swallowing problems in patients suffering with MS. However, future double-blind, randomized, and sham-controlled studies are needed to confirm the presen t findings. (Source: Neurological Sciences)
Source: Neurological Sciences - May 13, 2018 Category: Neurology Source Type: research

Hippocampal deep brain stimulation: persistent seizure control after bilateral extra-cranial electrode fracture
AbstractHippocampal deep brain stimulation (DBS) can provide an effective alternative for intractable temporal lobe epilepsy. In this case report, we describe a peculiar outcome after a post-traumatic wire-disconnection of a bilateral hippocampal DBS device. The patient presented a postoperative long-term significant reduction in seizure frequency even with an absent electric stimulation. This case gives the possibility to consider alternatives in epilepsy surgery, based on stimulation interference (lesional or electrical disturbing) in the epileptogenic zone. (Source: Neurological Sciences)
Source: Neurological Sciences - May 13, 2018 Category: Neurology Source Type: research

Incidence of sarcopenia and dynapenia according to stage in patients with idiopathic Parkinson ’s disease
ConclusionIn the early stages of chronic progressive diseases like IPD, identification of sarcopenia and dynapenia is important considering the limitations of disease-preventive effects in treatments applied after diagnosis. (Source: Neurological Sciences)
Source: Neurological Sciences - May 12, 2018 Category: Neurology Source Type: research

Semi-quantitative dopamine transporter standardized uptake value in comparison with conventional specific binding ratio in [123I] FP-CIT single-photon emission computed tomography (DaTscan)
AbstractPurposeWe developed a new analytical method to quantify the dopamine transporter (DAT) radiation dose in the striatum on [123I] FP-CIT single-photon emission computed tomography (SPECT). This method is based on the dopamine transporter standardized uptake value (DaTSUV). The purpose of this study was to compare DaTSUV with the classical specific binding ratio (SBR) in the discrimination of dopaminergic neurodegenerative diseases (dNDD) from non-dNDD.MethodSeventy-seven consecutive patients who underwent DaTscan were included. Patients were divided into a dNDD group (n = 44; 24 men, 20 women; median ag...
Source: Neurological Sciences - May 10, 2018 Category: Neurology Source Type: research

Romberg ratio coefficient in quiet stance and postural control in Parkinson ’s disease
Conclusion: Parkinson patients use the increase in CoP sway length and ellipse area to stabilize their balance and sight does not facilitate static postural control as in healthy subjects. (Source: Neurological Sciences)
Source: Neurological Sciences - May 8, 2018 Category: Neurology Source Type: research

Glioblastoma niches: from the concept to the phenotypical reality
AbstractRecently, the concept of niches as sites of tumor progression, invasion, and angiogenesis in glioblastoma (GB) has been extensively debated. Niches, considered the sites in which glioblastoma stem cells (GSCs) reside, have been classified as perivascular, perinecrotic, and invasive. However, from a neuropathological point of view, it is not easy to establish when a tumor structure can be considered a niche. The relevant literature has been reviewed in the light of our recent experience on the subject. As for perinecrotic niches, the occurrence of GSCs around necrosis is interpreted as triggered by hypoxia through H...
Source: Neurological Sciences - May 8, 2018 Category: Neurology Source Type: research

A novel device for continuous monitoring of tremor and other motor symptoms
In this study, 16 patients with movement disorders were recruited. While results need to be extended with further studies and clinical trials, the proposed device appears promising and suitable for the use as part of clinical trials and routine clinical practice fo r supporting the evaluation of motor symptoms, disease progression, and the quantification of therapeutic effects (Source: Neurological Sciences)
Source: Neurological Sciences - May 7, 2018 Category: Neurology Source Type: research

Focal cortical superficial siderosis due to hemorrhagic transformation of cortical microinfarction
(Source: Neurological Sciences)
Source: Neurological Sciences - May 7, 2018 Category: Neurology Source Type: research

Standardization and validation of a parallel form of the verbal and non-verbal recognition memory test in an Italian population sample
AbstractIn the neuropsychological assessment of several neurological conditions, recognition memory evaluation is requested. Recognition seems to be more appropriate than recall to study verbal and non-verbal memory, because interferences of psychological and emotional disorders are less relevant in the recognition than they are in recall memory paradigms. In many neurological disorders, longitudinal repeated assessments are needed to monitor the effectiveness of rehabilitation programs or pharmacological treatments on the recovery of memory. In order to contain the practice effect in repeated neuropsychological evaluation...
Source: Neurological Sciences - May 4, 2018 Category: Neurology Source Type: research

Coping strategies in caregivers of disorders of consciousness patients
ConclusionResults showed the importance to develop effective coping strategies aimed to reduce psychological distress and improving caregiver ’s well-being. (Source: Neurological Sciences)
Source: Neurological Sciences - May 4, 2018 Category: Neurology Source Type: research

Rapidly ascending necrotizing myelopathy with widespread brain white matter involvement following intrathecal methotrexate and cytosine arabinoside treatment in an adult with T cell acute lymphoblastic leukemia
(Source: Neurological Sciences)
Source: Neurological Sciences - May 4, 2018 Category: Neurology Source Type: research

Bulleidia extructa and Actinomyces israelii infections in a patient with brain abscess
(Source: Neurological Sciences)
Source: Neurological Sciences - May 4, 2018 Category: Neurology Source Type: research

Psychometric properties of the Italian version of the Cognitive Reserve Scale (I-CRS)
AbstractThe original definition of cognitive reserve (CR) refers to the individual differences in cognitive performance after a brain damage or pathology. Several proxies were proposed to evaluate CR (education, occupational attainment, premorbid IQ, leisure activities). Recently, some scales were developed to measure CR taking into account several cognitively stimulating activities. The aim of this study is to adapt the Cognitive Reserve Scale (I-CRS) for the Italian population and to explore its psychometric properties. I-CRS was administered to 547 healthy participants, ranging from 18 to 89  years old, along with ...
Source: Neurological Sciences - May 4, 2018 Category: Neurology Source Type: research

A simple measure of cognitive reserve is relevant for cognitive performance in MS patients
AbstractCognitive reserve (CR) contributes to preserve cognition despite brain damage. This theory has been applied to multiple sclerosis (MS) to explain the partial relationship between cognition and MRI markers of brain pathology. Our aim was to determine the relationship between two measures of CR and cognition in MS. One hundred and forty-seven MS patients were enrolled. Cognition was assessed using the Rao ’s Brief Repeatable Battery and the Stroop Test. CR was measured as the vocabulary subtest of the WAIS-R score (VOC) and the number of years of formal education (EDU). Regression analysis included raw score da...
Source: Neurological Sciences - May 4, 2018 Category: Neurology Source Type: research

Refractory epilepsy in Norrie disease
(Source: Neurological Sciences)
Source: Neurological Sciences - May 3, 2018 Category: Neurology Source Type: research

Advances in dialysis encephalopathy research: a review
AbstractDialysis encephalopathy (DE) is a progressive, fatal disease with a high mortality rate. Understanding the causes of this disease and the efforts to prevent and treat it would help improve the prognosis and quality of life of affected patients. This paper reviews the etiology, clinical features, methods of examining accessory features, diagnosis, treatment, and prevention of DE. We found that DE is likely to be related to aluminum poisoning. The clinical manifestations of DE include language disorders, mental and behavioral disorders, cognitive decline, and movement disorders. Electroencephalogram (EEG) findings ma...
Source: Neurological Sciences - May 2, 2018 Category: Neurology Source Type: research

The urgent neurological consultation in the population of the province of Ferrara, Italy
AbstractIn the province of Ferrara, Italy, the urgent neurological consultation (UNC) cases in the population correspond to the resident outpatients who undergo a UNC in the ER of the university hospital of Ferrara (UHFe). Thanks to this health organization a retrospective survey identified 612 UNC cases (range of age 7 –102 years, median 67,5 years) in the study period giving a period prevalence rate of 173 per 100,000 (95% CI 159.3–187.3) which increased with age (χ2 for trend  = 178.4p   0.70). The prevalence rate decreased with the distance between the patients&rsqu...
Source: Neurological Sciences - May 1, 2018 Category: Neurology Source Type: research

Meta-analysis of the association between ZNF512B polymorphism rs2275294 and risk of amyotrophic lateral sclerosis
AbstractAmyotrophic lateral sclerosis (ALS), the most common motor neuron disease, appears to result from the combination of genetic and environmental factors. Whether the rs2275294 polymorphism in theZNF512B gene influences ALS risk is controversial. We meta-analysed the association between rs2275294 and ALS risk based on evidence published in the PubMed database. Five case –control studies involving 2559 patients with sporadic ALS and 5740 controls were analysed. Based on random-effects meta-analysis, the polymorphism rs2275294 was associated with increased risk of ALS disease in an allele model (C vs. T: OR 1.222,...
Source: Neurological Sciences - May 1, 2018 Category: Neurology Source Type: research

The goblet sign in the amnestic syndrome of the subcallosal artery infarct
AbstractWe here describe an acute-onset amnesic syndrome with evidence of an embolic infarction in the distribution of the subcallosal artery, a proximal branch of the anterior communicating artery. The infarction involved the corpus callosum genu and both fornices, giving a peculiar image on MRI that resembled a goblet. Although infrequent, the subcallosal artery infarction should be considered in the differential diagnosis of patients with an acute amnestic syndrome. We propose “the goblet sign” for the peculiar diffusion-weighted MRI image of the brain in this syndrome. (Source: Neurological Sciences)
Source: Neurological Sciences - May 1, 2018 Category: Neurology Source Type: research

Contralateral Parkinson ’s disease in a patient with diabetic hemichorea
(Source: Neurological Sciences)
Source: Neurological Sciences - April 30, 2018 Category: Neurology Source Type: research

A longitudinal study of painless and painful intercostobrachial neuropathy after breast cancer surgery
AbstractIntercostobrachial neuropathy, often resulting in neuropathic pain, is a common complication of breast cancer surgery. In this 1-year longitudinal study, we aimed at seeking information on the frequency, clinical features, and course of painless and painful intercostobrachial neuropathy. We enrolled 40 women previously undergoing breast cancer surgery. In these patients, we collected, at 3, 6 and 12  months after surgery, clinical and quantitative sensory testing (QST) variables to diagnose intercostobrachial neuropathy, DN4 questionnaire to identify neuropathic pain, Neuropathic Pain Symptom Inventory to asse...
Source: Neurological Sciences - April 29, 2018 Category: Neurology Source Type: research

BK-virus progressive multifocal leukoencephalitis in a patient with systemic lupus erythematosus
(Source: Neurological Sciences)
Source: Neurological Sciences - April 28, 2018 Category: Neurology Source Type: research

Acute myelitis as presentation of a reemerging disease: measles
(Source: Neurological Sciences)
Source: Neurological Sciences - April 28, 2018 Category: Neurology Source Type: research

The Italian validation of the minimal assessment of cognitive function in multiple sclerosis (MACFIMS) and the application of the Cognitive Impairment Index scoring procedure in MS patients
AbstractCognitive dysfunction occurs in almost 50 –60% of patients with multiple sclerosis (MS) even in early stages of the disease and affects different aspects of patient’s life. Aims of the present study were (1) to introduce and validate an Italian version of the minimal assessment of cognitive functions in MS (MACFIMS) battery and (2) to p ropose the use of the Cognitive Impairment Index (CII) as a scoring procedure to define the degree of impairment in relapsing-remitting (RRMS) and secondary-progressive (SPMS) patients. A total of 240 HC and 123 MS patients performed the Italian version of the MACFIMS co...
Source: Neurological Sciences - April 27, 2018 Category: Neurology Source Type: research

Levetiracetam-induced rhabdomyolysis: the first Italian case
(Source: Neurological Sciences)
Source: Neurological Sciences - April 26, 2018 Category: Neurology Source Type: research

Neurobeh çet, multiple sclerosis or overlap syndrome? A case report
(Source: Neurological Sciences)
Source: Neurological Sciences - April 26, 2018 Category: Neurology Source Type: research

Correction to: The Italian Dystonia Registry: rationale, design and preliminary findings
AbstractIn the original article, Gina Ferrazzano was affiliated to Department of Neurology and Psychiatry, Neuromed Institute IRCCS, Sapienza University of Rome, Pozzilli, Italy.The corrected affiliation should be: Neuromed Institute IRCCS, Pozzilli, IS, Italy. (Source: Neurological Sciences)
Source: Neurological Sciences - April 18, 2018 Category: Neurology Source Type: research

Multiple sclerosis in the Republic of San Marino, Italian peninsula: an incidence and prevalence study from a high-risk area
AbstractEpidemiological studies on multiple sclerosis (MS) carried out in Southern Europe in the last years have shown a significant increase in the disease frequency. Previous surveys conducted in the Republic of San Marino, Northern Italian peninsula, identified  that the population is at high risk for MS, with a prevalence of 51.6 per 100,000 population in 1982 and of 166.7 in 2005 and with a mean annual incidence of 7.9 per 100,000 for the period 1990–2005. The present work is a community-based intensive prevalence and incidence survey, by a complete e numeration approach, to update the prevalence and i...
Source: Neurological Sciences - April 18, 2018 Category: Neurology Source Type: research

Cross-cultural adaptation and psychometric properties of the SCOPA-Sleep —German version
AbstractAim of the study was the cross-cultural adaptation and validation of the German version of the Scale for Outcomes in Parkinson ’s disease-Sleep Scale (SCOPA-Sleep) for assessment of night-time sleep problems (NS) and daytime sleepiness (DS). Eighty-three patients with Parkinson’s disease completed the SCOPA-Sleep and a multitude of measures for assessment of validity (e.g., PSQI, ESS). Twenty patients completed the SCOP A-Sleep twice within 2 months for assessment of retest reliability. Sixty-four healthy controls were also included for validity estimation. Internal consistency (Cronbach’s al...
Source: Neurological Sciences - April 14, 2018 Category: Neurology Source Type: research

Bilateral vestibular impairment in Vogt Koyanagi Harada syndrome: a case report
(Source: Neurological Sciences)
Source: Neurological Sciences - April 13, 2018 Category: Neurology Source Type: research

Interictal levels of calcitonin gene related peptide in gingival crevicular fluid of chronic migraine patients
AbstractCalcitonin gene related peptide (CGRP) is a mediator of neurogenic inflammation playing a major role in the pathogenesis of migraine. Increases in serum CGRP have been detected previously in migraineurs and a return to baseline values regarded as successful treatment. As gingival crevicular fluid is known to originate from the serum, the aim of this study is to measure the CGRP content of gingival crevicular fluid (GCF) in chronic migraine patients and to determine whether there is a correlation between serum and GCF values of CGRP. For this study, 24 female individuals suffering from chronic migraine with aura wer...
Source: Neurological Sciences - April 13, 2018 Category: Neurology Source Type: research

The correlation between growth hormone receptor (GHR) polymorphism and obstructive sleep apnea syndrome among the Han and Hani population in China
In conclusion, significant associa tions were detected between some SNPs in the GHR gene and OSAS occurrence while others appeared to be ethnicity-dependent. (Source: Neurological Sciences)
Source: Neurological Sciences - April 13, 2018 Category: Neurology Source Type: research

Biomarkers study in atypical dementia: proof of a diagnostic work-up
This study introduces a proof of diagnostic work-up that combines imaging and CSF biomarkers and suggests distinct ways to proceed on the basis of a greater diagnostic likelihood. (Source: Neurological Sciences)
Source: Neurological Sciences - April 13, 2018 Category: Neurology Source Type: research

Epilepsy in popular Medicine from the Classic Age to the Modern Age: a study on elk hoof as an original treatment
AbstractEuropean people believed that epilepsy was both a sacred and demoniac disease in the pre- and post-Hippocratic Age, and this belief continued into the Christian era. Epilepsy was wrapped in mystery. The present work shows an epileptic treatment using elk (Alces alces) hoof, which was better known among Northern European people, and explains its historical and popular origins that lead to its importance and success within the Official Medicine in the sixteenth and seventeenth centuries until its gradual decline as a specific treatment in the subsequent centuries. We study authors from both Antiquity and the Modern A...
Source: Neurological Sciences - April 12, 2018 Category: Neurology Source Type: research

The clinicopathological and prognostic significance of TP53 alteration in K27M mutated gliomas: an individual-participant data meta-analysis
This study aimed to investigate the impact of TP53 alteration on survival and clinicopathological features of glioma patients with H3K27M mutations. An individual-participant-data (IPD) meta-analysis was performed to investigate the impact of TP53 alteration on survival and clinicopathological features of patients with H3K27M mutations. Three hundred thirty-one individual records from 12 eligible glioma studies involving the H3K27M mutation were finally included in our meta-analysis, and a pooled hazard ratio (HR) of 1.53 (95%CI, 1.10 –2.11;P = 0.01) indicated that TP53 alterations were associated with ...
Source: Neurological Sciences - April 12, 2018 Category: Neurology Source Type: research

Functional MRI and laser-evoked potentials evaluation in Charcot-Marie-Tooth syndrome
We described a case of a 39-year-old male patient affect by Charcot-Marie-Tooth (CMT) disease compared to five healthy controls (HC), to assess the sensory and the nociceptive pathways by using LEPs recording associated to fMRI examination, to find an “objective” marker which could be used in the management of CMT patient. The nociceptive system was evaluated by laser-evoked potentials (LEPs). Moreover, fMRI (functional magnetic resonance imaging) examination, by using laser stimuli, was performed. LEPs’ examination showed an increase of la tency and an amplitude reduction respect to HC. The laser stimula...
Source: Neurological Sciences - April 11, 2018 Category: Neurology Source Type: research

Unilateral hyperhidrosis as persistently isolated feature of syringomyelia and Arnold Chiari type 1
(Source: Neurological Sciences)
Source: Neurological Sciences - April 10, 2018 Category: Neurology Source Type: research

The association of NF2 (neurofibromin 2) gene polymorphism and the risk of medulloblastomas
AbstractTo explore the relationship between NF2 promoter gene mutation and the risk of medulloblastomas (MBs). We collected tissues from 16 MB patients and 7 age-matched non-MB controls. Gene sequencing, qPCR (real-time quantitative polymerase chain reaction), IHC (immunohistochemistry), and WB (Western blot) were used to analyze the changes in the NF2 gene sequence and expression between patients and controls. We found that NF2 promoter gene mutations occurred in MB patients. The NF2 mRNA expression was higher in the controls than in patients (p = 0.03 
Source: Neurological Sciences - April 10, 2018 Category: Neurology Source Type: research

Healthcare resources utilisation in primary progressive multiple sclerosis
This study was aimed to evaluate the burden of PPMS in Italy with healthcare resources utilisation and costs for Italian National Health System (INHS). A 2-year cross-sectional analysis of real-world data collected in the ARCO database, covering>  10 million Italian inhabitants, was performed. From a cohort of patients affected by MS in 2014, those supposedly affected by PPMS were defined by the concurrent matching of absence of disease-modifying treatments and use of rehabilitation services. Any other drug prescriptions, outpatient servic es and hospitalisations were analysed in 2015 for each subject. The averag...
Source: Neurological Sciences - April 10, 2018 Category: Neurology Source Type: research

Thrombomodulin, alarmin signaling, and copeptin: cross-talk between obesity and acute ischemic stroke initiation and severity in Egyptians
In conclusion, these results highlighted detr imental role of alarmin signaling with increased adaptive response to block this pathway through TM in addition to increased copeptin level as an acute damage marker and their tight relation to WC not to BMI in AIS which clarify the implication of central adiposity. (Source: Neurological Sciences)
Source: Neurological Sciences - April 10, 2018 Category: Neurology Source Type: research

The rise of soluble platelet-derived growth factor receptor β in CSF early after subarachnoid hemorrhage correlates with cerebral vasospasm
AbstractPlatelet-derived growth factor β (PDGFβ) has been proposed to contribute to the development of cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH), and soluble PDGFRβ (sPDGFRβ) is considered to be an inhibitor of PDGF signaling. We aimed at determining the sPDGFRβ concentrations in the cerebrospinal fluid (CSF) of p atients with aneurysmal SAH (aSAH) and analyzing the relationship between sPDGFRβ level and CVS. CSF was sampled from 32 patients who suffered aSAH and five normal controls. Enzyme-linked immunosorbent assay was performed to determine the sPDGFRβ concentration...
Source: Neurological Sciences - April 10, 2018 Category: Neurology Source Type: research

Peritoneum as an origin of epilepsy from the viewpoint of Avicenna
This article presents concept of Maraqq-related epilepsy; according to Avicenna’s view, “Maraqq” is a membranous structure which is located in the abdomen (equivalent of parietal peritoneum in current nomenclature). We discuss his viewpoint about the diagnosis and treatment of Maraqq-related epilepsy with focus on herbal remedies. The concept of a relationship between the “Maraqq” and the brain is well discussed in the old Persian medicine texts; however, it seems that further studies in this area are required to clarify Avicenna’s view about the pathophysiological mechanisms, clinical m...
Source: Neurological Sciences - April 9, 2018 Category: Neurology Source Type: research

Therapeutic potential of vitamin E and its derivatives in traumatic brain injury-associated dementia
AbstractTraumatic brain injury is one of the most common causes for intervention in neurosurgery. Apart from its acute consequence, it can represent a further burden on individuals as well as society by being associated with significant comorbidity —mainly early-onset dementia. Oxidative stress is one of the crucial mechanisms conferring the damage to nervous tissue, and it is believed it could be, to some extent, influenced by dietary composition, largely by antioxidants contained in the diet. Under stressful conditions, cell-derived reacti ve oxygen species in the brain can induce the formation of lipid peroxides a...
Source: Neurological Sciences - April 7, 2018 Category: Neurology Source Type: research

Orthostatic hypotension acutely impairs executive functions in Parkinson ’s disease
AbstractOrthostatic hypotension is a frequent non-motor symptom of Parkinson ’s disease, with negative prognostic role on cognitive functions. Here we measured the acute effects of orthostatic hypotension on executive functions in Parkinson’s disease patients devoid of hypertension, carotid artery stenosis, and significant chronic cerebrovascular pathology. Measurements were carried out during regular visits in outpatient setting. Twenty-eight Parkinson’s disease patients were recruited and studied along scheduled outpatient visits. They were divided into two groups (n = 14 each) based on th...
Source: Neurological Sciences - April 7, 2018 Category: Neurology Source Type: research

False-negative diagnostic imaging of Wallenberg ’s syndrome by diffuse-weighted imaging: a case report and literature review
AbstractHere, we report a case of a 64-year-old female with acute-onset vertigo, nausea, and vomiting. In an emergency imaging examination, the results of computed tomography (CT) and diffusion weighted imaging (DWI) were negative. However, on 1  day post-hospital admission, a small acute infarct in the posterolateral aspect of the left medulla was detected by DWI. Extra attention should be payed to the false-negative imaging results to avoid diagnosis and treatment delay. (Source: Neurological Sciences)
Source: Neurological Sciences - April 7, 2018 Category: Neurology Source Type: research