Cardiac autonomic involvement in Huntington ’s disease
ConclusionCardiac disfunction increases, and autonomic functions change in HD, but more comprehensive studies are needed to distinguish sympathetic and parasympathetic involvement. (Source: Neurological Sciences)
Source: Neurological Sciences - March 4, 2024 Category: Neurology Source Type: research
The Glasgow Coma Scale: 50-year anniversary
AbstractIn 1974, Sir Graham Teasdale and Bryan Jennett wrote the “Assessment of coma and impaired consciousness, A practical scale,” which has become one of the most influential papers in the history of traumatic brain injury, with more than 10,000 citations as of January 2024. Today, it is one of the most widely used tools in emergency departments, providing a reliable general overview of the patient’s consciousness status. (Source: Neurological Sciences)
Source: Neurological Sciences - March 4, 2024 Category: Neurology Source Type: research
Advances in using ultrasound to regulate the nervous system
This article mainly explores the pos sible mechanisms of ultrasound’s mechanical effects, cavitation effects, thermal effects, and the rise of sonogenetics. In addition, the essence of action potential and its relationship with ultrasound were also discussed. Traditional theory treats nerve impulses as pure electrical signals, simila r to cable theory. However, this theory cannot explain the phenomenon of inductance and cell membrane bulging out during the propagation of action potential. Therefore, the flexoelectric effect of cell membrane and soliton model reveal that action potential may also be a mechanical wave. Fin...
Source: Neurological Sciences - March 4, 2024 Category: Neurology Source Type: research
A novel pathogenic variant in TDP2 causes spinocerebellar ataxia autosomal recessive 23 accompanied by pituitary tumor and hyperhidrosis: a case report
AbstractTDP2 gene encodes tyrosyl DNA phosphodiesterase 2, an enzyme required for effective repair of the DNA double-strand breaks (DSBs). Spinocerebellar ataxia autosomal recessive 23 (SCAR23) is a rare disease caused by the pathogenic mutation of TDP2 gene and characterized by intellectual disability, progressive ataxia and refractory epilepsy. Thus far, merely nine patients harboring five different variants (c.425 + 1G > A; c.413_414delinsAA, p. Ser138*; c.400C > T, p. Arg134*; c.636 + 3_ 636 + 6 del; c.4G > T, p. Glu2*) in TDP2 gene have been reported. Here, we describe the tenth pa...
Source: Neurological Sciences - March 4, 2024 Category: Neurology Source Type: research
Atypical and delayed spinal cord MRI features of COVID-19-associated myelopathies: a report of four cases and literature review
This report highlights the recognition of COVID-19-associated myelopathy even months after initial infection, especially in patients with delayed and atypical spinal cord findings on MRI. (Source: Neurological Sciences)
Source: Neurological Sciences - March 2, 2024 Category: Neurology Source Type: research
Serial 18F-FDG PET/CT findings in a patient with Acute Wernicke Encephalopathy
(Source: Neurological Sciences)
Source: Neurological Sciences - March 1, 2024 Category: Neurology Source Type: research
Marked neuropsychiatric involvement and dysmorphic features in nemaline myopathy
ConclusionWe raise the need for further studies regarding the role of thin filament proteins in the central nervous system and for a systematic cognitive assessment of congenital myopathy patients. (Source: Neurological Sciences)
Source: Neurological Sciences - February 10, 2024 Category: Neurology Source Type: research
Parkinsonism with prominent neuropsychiatric symptoms without pyramidal involvement in a patient with FBXO7 variants
(Source: Neurological Sciences)
Source: Neurological Sciences - February 10, 2024 Category: Neurology Source Type: research
Autosomal recessive spino-cerebellar ataxia type 10 (SCAR10): clinical presentation associated with c.289delA ANO10 gene variant
(Source: Neurological Sciences)
Source: Neurological Sciences - February 10, 2024 Category: Neurology Source Type: research
Superficial siderosis of the central nervous system caused by myxopapillary ependymoma of cauda equine: a case report
(Source: Neurological Sciences)
Source: Neurological Sciences - February 10, 2024 Category: Neurology Source Type: research
Influenza B-induced longitudinally extensive transverse myelitis and bithalamic acute disseminated encephalomyelitis
AbstractIn the COVID-era, other viral pathogens, like influenza B, gain less attention in scientific reporting. However, influenza still is endemic, and rarely affects central nervous system (CNS). Here, we report the case of a 35-year-old male who presented with fever since 1 week, and developed acute ascending flaccid paralysis and urinary retention. The clinical presentation of paraparesis in combination with the inflammation proven by the lumbar puncture, and the MRI full spine, fulfilled the diagnostic criteria of longitudinally extensive transverse myelitis (LETM) . In this case, it is most likely based on a post-v...
Source: Neurological Sciences - February 10, 2024 Category: Neurology Source Type: research
Efgartigimod improves triple-negative myasthenia gravis
(Source: Neurological Sciences)
Source: Neurological Sciences - February 10, 2024 Category: Neurology Source Type: research
Dynamic diffusion imaging changes and unique midbrain involvement in a probable MV2K sCJD
(Source: Neurological Sciences)
Source: Neurological Sciences - February 10, 2024 Category: Neurology Source Type: research
Post-traumatic carotid-cavernous fistula
AbstractA 28-year-old woman who suffered a head injury 2 months before presented with a history of progressive right eye proptosis, ophthalmoplegia, and conjunctival injection. The radiological workup with a magnetic resonance imaging of the brain and cerebral angiography revealed a direct, high-flow, right post-traumatic carotid-cavernous fistula. An endovascular procedure was performed, and the carotid-cavernous fistula was successfully occluded with a progressive resolution of the complained symptoms. (Source: Neurological Sciences)
Source: Neurological Sciences - February 10, 2024 Category: Neurology Source Type: research
Letter to the Editor: a case of autoimmune glial fibrillary acidic protein astrocytopathy with acute paralytic ileus as initial symptom
(Source: Neurological Sciences)
Source: Neurological Sciences - February 10, 2024 Category: Neurology Source Type: research
