Filtered By:
Condition: Autoimmune Disease

This page shows you your search results in order of date. This is page number 20.

Order by Relevance | Date

Total 584 results found since Jan 2013.

Anaphylaxis-induced atrial fibrillation and anesthesia: Pathophysiologic and therapeutic considerations.
Abstract Atrial fibrillation is the most common cardiac arrhythmia in western society affecting more than 35 million individuals worldwide annually. It is a common postoperative complication and may also occur spontaneously during general and local anesthesia administration. Aging, diabetes mellitus, hypertension, and cardiovascular diseases including cardiomyopathies, congenital cardiac anomalies, heart failure, myocardial ischemia, pericarditis, previous cardiac surgery, vascular disease, and valvular heart disease are some correlated factors. Beyond age, increased incidence of atrial fibrillation has been corre...
Source: Annals of Cardiac Anaesthesia - December 31, 2019 Category: Anesthesiology Authors: Kounis NG, Koniari I, Tzanis G, Soufras GD, Velissaris D, Hahalis G Tags: Ann Card Anaesth Source Type: research

A Case of Fabry Disease Presenting with Young Stroke and Fever.
Authors: Wu LC, Chiang CT, Lee KF Abstract Although it is known that Fabry disease should be included in the differential diagnosis of young stroke and fever of unknown origin, it has not been reported in the literature of stroke with fever as the presentation of Fabry disease. This is relevant because stroke with fever may misguide the differential diagnosis. Here we present a young stroke patient with fever. DWI of brain MRI revealed acute multiple infarctions. Due to the fever, infectious and inflammatory origins such as infective endocarditis and autoimmune diseases were examined first. However, we could not id...
Source: Acta Neurologica Taiwanica - December 25, 2019 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Mumps encephalitis with bilateral hippocampal lesions preceding parotitis
Bilateral hippocampal lesions can be a feature in both infectious and autoimmune limbic encephalitis. Although rare, mumps meningoencephalitis should be considered in the differential diagnosis of bilateral hippocampal lesions, especially in the presence of symptoms suggestive of systemic and/or CNS infection.
Source: Neurology Clinical Practice - December 8, 2019 Category: Neurology Authors: Chee, Y. C., Ong, B. H. Tags: MRI, Encephalitis, All Clinical Neurology, All Cerebrovascular disease/Stroke, EEG; see Epilepsy/Seizures Case Source Type: research

Orthostatic hypotension and cardiovascular risk.
Abstract Orthostatic hypotension (OH) is a cardinal sign of cardiovascular (CV) autonomic dysfunction as a result of autonomic nervous system failure to control the postural hemodynamic homeostasis. The proportion of individuals with OH increases with aging and chronic conditions, such as neurodegenerative diseases, hypertension, heart failure, diabetes, renal dysfunction, autoimmune diseases and cancer. In those over 70 years, more than 20% can be affected. It is now increasingly recognized that a direct relationship exists between OH and each step of the CV disease continuum, eventually leading to end-stage hear...
Source: Polish Heart Journal - November 7, 2019 Category: Cardiology Authors: Fedorowski A, Ricci F, Sutton R Tags: Kardiol Pol Source Type: research

A challenging diagnosis of reversible “vascular” dementia: Cerebral amyloid angiopathy-related inflammation
We describe the clinical course, radiological features and therapeutic approach of two patients with probable CAA-ri with the aim of emphasizing the importance of an early diagnosis of this potentially reversible disease in different neurological settings, such as memory clinics and stroke units.
Source: Journal of Neuroimmunology - November 6, 2019 Category: Allergy & Immunology Authors: L. Poli, V. De Giuli, F. Piazza, I. Volonghi, G. Bigliardi, S. Vallone, P.F. Nichelli, R. Gasparotti, A. Zini, A. Padovani, A. Pezzini Tags: Short Communication Source Type: research

Global Characterization of Circulating Nucleic Acids.
Abstract Circulating nucleic acids (CNAs) include genomic and mitochondrial DNA fragments, small RNAs, and bacterial and viral DNA/RNA. Different mechanisms such as cell apoptosis, necrosis, and active CNA release from cells have been proposed to result in nucleic acids in the circulation. Application of next generation sequencing technology demonstrated that CNAs contain specific mutations, indels, microsatellite alterations, and epigenetic changes (DNA methylation) associated with various diseases. Their clinical implications have been demonstrated for diseases such as cancer, stroke, trauma, myocardial infarcti...
Source: Mol Biol Cell - November 1, 2019 Category: Molecular Biology Authors: Dunaeva M, Pruijn GJM Tags: Methods Mol Biol Source Type: research

Behcet's Disease With Cerebral Artery Infarction Caused by Cerebral Arteritis as an Early Symptom Only With Elevated Interleukin-8
Conclusion: This case demonstrates that neurological involvement might be an early symptom of BD. IL-8 could act as a novel target for the treatment of BD theoretically and probably play a key role in disease recovery.
Source: Frontiers in Neurology - October 21, 2019 Category: Neurology Source Type: research

Patterns of serum lipids derangements and cardiovascular risk assessment in patients with primary biliary cholangitis.
CONCLUSIONS: Marked derangements in serum lipids and a high frequency of dyslipidemias are found in patients with PBC, however, these do not increase the risk of cardiovascular events. PMID: 31506216 [PubMed - as supplied by publisher]
Source: Annals of Hepatology - September 12, 2019 Category: Gastroenterology Tags: Ann Hepatol Source Type: research

Activated protein C ameliorates chronic graft-versus-host disease by PAR1-dependent biased cell signaling on T cells
Soluble thrombomodulin plasma concentrations are elevated in steroid-resistant graft-versus-host disease (GVHD), implying endothelial hypofunctioning for thrombomodulin-dependent generation of activated protein C’s (APC) anticoagulant, anti-inflammatory, and antiapoptotic functions. Recombinant thrombomodulin or APC administration decreases acute GVHD, manifested by intense inflammation and tissue destruction. Here, we administered recombinant murine wild-type (WT) APC to mice with established chronic GVHD (cGVHD), a less-inflammatory autoimmune-like disease. WT APC normalized bronchiolitis obliterans–induced p...
Source: Blood - August 28, 2019 Category: Hematology Authors: Sinha, R. K., Flynn, R., Zaiken, M., Paz, K., Gavin, A. L., Nemazee, D., Fernandez, J. A., Xu, X., Griffin, J. H., Blazar, B. R. Tags: Transplantation, Brief Reports Source Type: research

Getting the Right Care for Painful Autoimmune Conditions
A corticosteroid can quickly relieve symptoms of both polymyalgia rheumatica and temporal arteritis. But a delay could cause vision loss, a stroke or even death.
Source: NYT Health - August 19, 2019 Category: Consumer Health News Authors: Jane E. Brody Tags: Stroke Steroids Autoimmune Diseases Immune System Source Type: news

Central Nervous System Opportunistic Infections
Semin Neurol 2019; 39: 383-390 DOI: 10.1055/s-0039-1687842Opportunistic infections of the central nervous system are classically associated with immunosuppression arising from infection with human immunodeficiency virus and with various hematologic malignancies. However, over the past few years, they are increasingly associated with transplantation and various immunosuppressive treatments used to treat autoimmune diseases. They cause significant morbidity and mortality and remain a diagnostic challenge due to the absence of typical signs and symptoms of infection and mimicry by various noninfectious causes. The pathogens a...
Source: Seminars in Neurology - August 1, 2019 Category: Neurology Authors: Agnihotri, Shruti P. Tags: Review Article Source Type: research

Treating psoriasis with injections may offset sufferers' higher risk of heart disease, study finds
Injection drugs used to treat the common autoimmune skin condition also alleviated blood vessel inflammation and fat buildup linked to heart attack and stroke, a new NIH study suggests.
Source: the Mail online | Health - July 31, 2019 Category: Consumer Health News Source Type: news

Regulatory T Cells: Pathophysiological Roles and Clinical Applications.
Abstract Inflammation and immune responses after tissue injury play pivotal roles in the resolution of inflammation, tissue recovery, fibrosis, and remodeling. Regulatory T cells (Tregs) are responsible for immune tolerance and are usually activated in secondary lymphatic tissues. Activated Tregs subsequently regulate effector T cell and dendritic cell activation. For clinical applications such as the suppression of both autoimmune diseases and the rejection of transplanted organs, methods to generate stabilized antigen-specific Tregs are required. For this purpose, transcriptional and epigenetic regulation of Fox...
Source: The Keio Journal of Medicine - July 25, 2019 Category: Universities & Medical Training Authors: Sakai R, Komai K, Iizuka-Koga M, Yoshimura A, Ito M Tags: Keio J Med Source Type: research

Application and prospects of butylphthalide for the treatment of neurologic diseases.
CONCLUSIONS: The varied pharmacologic mechanisms of NBP involve many complex molecular mechanisms; however, there many unknown pharmacologic effects await further study. PMID: 31205106 [PubMed - in process]
Source: Chinese Medical Journal - June 18, 2019 Category: General Medicine Authors: Chen XQ, Qiu K, Liu H, He Q, Bai JH, Lu W Tags: Chin Med J (Engl) Source Type: research

What Causes Facial Nerve Palsy?
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news