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Condition: Autoimmune Disease
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Total 584 results found since Jan 2013.
The role of the indoles in microbiota-gut-brain axis and potential therapeutic targets: A focus on human neurological and neuropsychiatric diseases
Neuropharmacology. 2023 Aug 22:109690. doi: 10.1016/j.neuropharm.2023.109690. Online ahead of print.ABSTRACTAt present, a large number of relevant studies have suggested that the changes in gut microbiota are related to the course of nervous system diseases, and the microbiota-gut-brain axis is necessary for the proper functioning of the nervous system. Indole and its derivatives, as the products of the gut microbiota metabolism of tryptophan, can be used as ligands to regulate inflammation and autoimmune response in vivo. In recent years, some studies have found that the levels of indole and its derivatives differ signifi...
Source: Neuropharmacology - August 24, 2023 Category: Drugs & Pharmacology Authors: Yi Zhou Yue Chen Hui He Meichang Peng Meiqin Zeng Haitao Sun Source Type: research
A patient with MELAS syndrome combined with autoimmune abnormalities: a case report
ConclusionMitochondrial encephalomyopathy is a rare clinical condition; however, the association with autoimmune diseases is not yet clear and still needs further research and analysis.
Source: Frontiers in Neurology - August 24, 2023 Category: Neurology Source Type: research
Scientists Are Just Beginning to Understand COVID-19 ’ s Effect On the Brain
Early in the COVID-19 pandemic, doctors started to notice something striking. For what was originally described as a respiratory virus, SARS-CoV-2 seemed to have a strong effect on the brain, causing everything from loss of taste and smell and brain fog to, in serious cases, stroke.
NYU Langone Health, a New York city research hospital, started collating those anecdotes in hopes of better understanding how the virus affects the brain and nervous system. Years later, the project has morphed from focusing solely on acute symptoms to also tracking the long-term neurologic issues that some people with Long COVID experience, sa...
Source: TIME: Health - July 17, 2023 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news
Mitochondrial encephalopathy with lactic-acidosis and stroke-like episodes syndrome presenting as progressive supranuclear palsy
Clinical manifestations of MELAS are broad and include stroke-like episodes, myopathy, cardiomyopathy, headaches, hearing impairment, dementia, epilepsy, lactic acidemia, cyclic vomiting, diabetes, and short stature. Most cases of MELAS present early in childhood, with only 1 –6% presenting after the age of 40 [1]. Progressive supranuclear palsy (PSP) is a neurodegenerative disorder which can be mimicked by a variety of conditions, such as CADASIL, cerebrovascular disease, and autoimmune encephalitis [2].
Source: Parkinsonism and Related Disorders - July 7, 2023 Category: Neurology Authors: Reece M. Hass, Jennifer L. Whitwell, Elizabeth Y. Coon, Keith A. Josephs, Farwa Ali Tags: Correspondence Source Type: research
Myasthenia Gravis and Ischemic Stroke: A Bidirectional Mendelian Randomization Study
CONCLUSION: Bidirectional MR analysis did not provide evidence to support a causal relationship between genetically predicted MG and IS, although observational studies have found such a potential link.PMID:37403387 | DOI:10.2174/1567202620666230703122140
Source: Current Neurovascular Research - July 5, 2023 Category: Neurology Authors: Chen Liu Chengyuan Mao Shen Li Yun Su Hongbing Liu Xin Wang Weishi Liu Jiawei Zhao Xuyang Liu Yuming Xu Source Type: research
Risk factors for cardiovascular disease in primary Sj ögren’s syndrome (pSS): a 20-year follow-up study
ConclusionsExtraglandular involvement was associated with a higher prevalence of arterial hypertension, dyslipidemia, hyperuricemia, and coronary artery disease. Anti-Ro/SSA and anti-La/SSB seropositivity was associated with a higher prevalence of cardiac rhythm abnormalities, hyperuricemia, venous thrombosis, coronary artery disease, and cerebrovascular disease. Raised inflammatory markers, disease activity measured by ESSDAI, extraglandular involvement, serologic markers including hypergammaglobulinemia and low C3, and treatment with corticosteroids were associated with a higher risk for cardiovascular comorbidities.Key ...
Source: Clinical Rheumatology - July 4, 2023 Category: Rheumatology Source Type: research
Outcomes of therapeutic plasma exchange in severe autoimmune hemolytic anemia hospitalizations: An analysis of the National Inpatient Sample
CONCLUSION: Hospitalizations with severe AIHA that received TPE had higher rates of adverse in-hospital outcomes.PMID:37395043 | DOI:10.1111/trf.17445
Source: Transfusion - July 3, 2023 Category: Hematology Authors: Ali Abdelhay Amir A Mahmoud Omar Ammari Rami Dalbah Mouna Reghis Anas Hashem Mouaz Alkasem Mariam Mostafa Source Type: research
A knowledge-based decision support system for inferring supportive treatment recommendations for diabetes mellitus
CONCLUSION: The results obtained are promising in demonstrating the applicability, effectiveness, and efficiency of the tool. It can ensure that necessary precautions are taken in advance by raising awareness of society against the DM risk.PMID:37393457 | DOI:10.3233/THC-230237
Source: Technology and Health Care - July 2, 2023 Category: Medical Devices Authors: Duygu Çelik Ertuğrul Ne şe Akcan Yiltan Bitirim Begum Koru Mahmut Sevince Source Type: research
