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Condition: Autoimmune Disease

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Total 584 results found since Jan 2013.

Prevalence and associated relating factors in patients with hereditary retinal dystrophy: a nationwide population-based study in Taiwan
CONCLUSIONS: 74% of the diagnosed HRD are retinitis pigmentosa. Population-based data suggested an increased incidence of cataract in younger patients, whereas older HRD patients are more susceptible to develop CME. Further work is needed to elucidate the mechanism between these ophthalmological disorders and HRD.PMID:35396285 | DOI:10.1136/bmjopen-2021-054111
Source: Cancer Control - April 9, 2022 Category: Cancer & Oncology Authors: Peng Yeong Woon Jia-Ying Chien Jen-Hung Wang Yu-Yau Chou Mei-Chen Lin Shun-Ping Huang Source Type: research

Oral tolerance: an updated review
Immunol Lett. 2022 Apr 5:S0165-2478(22)00041-4. doi: 10.1016/j.imlet.2022.03.007. Online ahead of print.ABSTRACTOral tolerance (OT) has classically been defined as the specific suppression of cellular and/or humoral immune responses to an antigen by prior administration of the antigen through the oral route. Multiple mechanisms have been proposed to explain the induction of OT including T cell clonal depletion and anergy when high doses of antigens are fed, and regulatory T (Treg) cell generation following oral administration of low and repeated doses of antigens. Oral antigen administration suppresses the immune response ...
Source: Immunology Letters - April 8, 2022 Category: Allergy & Immunology Authors: Rafael M Rezende Howard L Weiner Source Type: research

Prevalence and associated relating factors in patients with hereditary retinal dystrophy: a nationwide population-based study in Taiwan
Conclusions 74% of the diagnosed HRD are retinitis pigmentosa. Population-based data suggested an increased incidence of cataract in younger patients, whereas older HRD patients are more susceptible to develop CME. Further work is needed to elucidate the mechanism between these ophthalmological disorders and HRD.
Source: BMJ Open - April 8, 2022 Category: General Medicine Authors: Woon, P. Y., Chien, J.-Y., Wang, J.-H., Chou, Y.-Y., Lin, M.-C., Huang, S.-P. Tags: Open access, Ophthalmology Source Type: research

Immunomodulatory Therapeutic Effects of Curcumin on M1 / M2 Macrophage polarization in Inflammatory Diseases
CONCLUSION: Curcumin not only enhances anti- tumor immunity (via shifting M polarization towards to M1 phenotype and/or up-regulation of M1 markers expression), but ameliorates inflammatory diseases including auto immune diseases (experimental autoimmune myocarditis and Behcet's disease), nephropathy, chronic serum sickness, stroke and atherosclerosis.PMID:35331128 | DOI:10.2174/1874467215666220324114624
Source: Atherosclerosis - March 25, 2022 Category: Cardiology Authors: Elham Abdollahi Thomas P Johnston Zahra Ghaneifar Parviz Vahedi Pouya Goleij Sara Azhdari Abbas Shapouri Moghaddam Source Type: research

Association of autoimmune blistering disease, and specifically, pemphigus vulgaris, with cardiovascular disease and its risk factors: a systematic review and meta-analysis
The objective of the study was to systematically review the relationship of  AIBD, including pemphigus vulgaris (PV), and its treatment with CVD and CVD risk factors. MEDLINE, EMBASE, Cochrane, LILACS, SCOPUS, and Web of Science were searched. We included all studies of CVD and CVD risk factors in AIBD patients. Two reviewers performed title and/or abstract review and da ta extraction. Pooled random-effects meta-analysis was performed. Forty papers met inclusion criteria. AIBD was associated with higher odds of diabetes (DM) (odds ratio [95% confidence interval]: 1.809 [1.258–2.601]), hypertension (HTN) (1.393 [1.088â...
Source: Archives of Dermatological Research - March 9, 2022 Category: Dermatology Source Type: research

REM sleep behavior disorder as a complex condition with heterogeneous underlying disorders: clinical management and prognostic implications Commentary
CONCLUSIONS: The clinical and research RBD fields span across the disciplines of neurology, pulmonary, psychiatry, psychology, and pediatric sleep medicine, along with physical medicine and rehabilitation medicine, other allied disciplines, and the basic and clinical neurosciences.PMID:35239134 | DOI:10.1007/s11325-022-02574-6
Source: Sleep and Breathing - March 3, 2022 Category: Sleep Medicine Authors: Carlos H Schenck Source Type: research

Pinocembrin Reduces Keratinocyte Activation and Ameliorates Imiquimod-Induced Psoriasis-like Dermatitis in BALB/c Mice through the Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Pathway
In this study, we evaluated the effects of pinocembrin on human HaCaT keratinocytes and BALB/c mice with imiquimod- (IMQ-) induced psoriatic dermatitis. In interferon-γ- (IFN-γ-) activated HaCaT cells, pinocembrin reduced the expression of inflammatory cytokines, namely, tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and keratinocyte proliferation markers, namely, keratin (K)16, K17, and Ki-67. The mechanism underlying these inhibitory effects involved the regulation of the heme oxygenase- (HO-) 1/signal transducer and activator of transcription (STAT) 3 pathway. In the IMQ-induced psoriatic dermatitis mouse mo...
Source: Evidence-based Complementary and Alternative Medicine - February 4, 2022 Category: Complementary Medicine Authors: Kuo-Kuei Huang Meng-Nan Lin Hui-Chun Hsu Yi-Ling Hsu Ting-Ni Huang I-Huang Lu I-Hong Pan Source Type: research