The role of thymic stromal lymphopoietin in cutaneous disorders
AbstractThymic Stromal Lymphopoietin (TSLP) is an important cytokine that invokes early immune responses. TSLP, an IL-7-like cytokine encoded by theTSLP gene, activates JAK1 and JAK2 signaling pathways, stimulating dendritic cells to induce inflammatory Th2 cells. This cytokine is associated with pruritus in various cutaneous disorders, particularly atopic dermatitis. Varying levels of the cytokine TSLP have been demonstrated in studies of different cutaneous disorders. Pharmacological treatment targeting TSLP has been explored recently, particularly in the realm of atopic dermatitis.This review explores the relation of TS...
Source: Archives of Dermatological Research - April 17, 2024 Category: Dermatology Source Type: research

Prevalence of obstructive sleep apnea with hidradenitis suppurativa: a matched case-control study
(Source: Archives of Dermatological Research)
Source: Archives of Dermatological Research - April 17, 2024 Category: Dermatology Source Type: research

Efficacy and safety of botulinum toxin in treating scleroderma-associated raynaud ’s phenomenon: a systematic review and meta-analysis
(Source: Archives of Dermatological Research)
Source: Archives of Dermatological Research - April 17, 2024 Category: Dermatology Source Type: research

Sentinel lymph node biopsy versus observation in high risk cutaneous squamous cell carcinoma of head and neck: a propensity score matching analysis
AbstractSentinel lymph node biopsy (SLNB) has gained considerable attention in the management of head and neck cutaneous squamous cell carcinoma (HNcSCC). The aim of this study was to compare the oncologic outcomes between observation and SLNB in cN0 high-risk HNcSCC patients. We retrospectively enrolled patients from the SEER database and evaluated the impact of observation versus SLNB on disease-specific survival (DSS) and overall survival (OS) using a Propensity Score Matching (PSM) analysis. A total of 9804 patients were included, with 1169 cases treated by SLNB. Successful retrieval of the sentinel lymph node was achi...
Source: Archives of Dermatological Research - April 16, 2024 Category: Dermatology Source Type: research

The role of teledermatology in Mohs micrographic surgery: a review
This study underscores TD’s multifaceted benefits in MMS: enhanced patient experience preopera tively, improved communication during surgery, and cost-effective postoperative follow-up. Limitations include the financial expense and technical issues that can arise with TD (connectivity problems, delays in video/audio transmission, etc.). Further studies are needed to explore emerging TD modali ties in post-operative patient management. The integration of TD into MMS signifies a progressive step in dermatological care, offering convenient, cost-effective, and better solutions with the potential to enhance patient experienc...
Source: Archives of Dermatological Research - April 16, 2024 Category: Dermatology Source Type: research

Association between miR-202, miR-211, and miR-1238 gene polymorphisms and risk of vitiligo
AbstractVitiligo, as a common pigment defect in the skin, hair, and mucous membranes, results from the destruction of melanocytes. Recent investigations have shown that miRNA dysregulation contributes in the pathogenesis of vitiligo. Therefore, in this research, our aim is to explore the relationship between miR-202 rs12355840, miR-211 rs8039189, and miR-1238 rs12973308 polymorphisms and susceptibility to vitiligo. A total number of 136 vitiligo patients and 129 healthy individuals as a control group were included in this research. The salting out approach was implemented to extraction genomic DNA. The genetic polymorphism...
Source: Archives of Dermatological Research - April 10, 2024 Category: Dermatology Source Type: research

Understanding patient demographics and treatment strategies observed in the follicular occlusion triad and tetrad
(Source: Archives of Dermatological Research)
Source: Archives of Dermatological Research - April 4, 2024 Category: Dermatology Source Type: research

Characterization of alopecia clinical trials: an analysis of trials registered on clinicaltrials.gov
(Source: Archives of Dermatological Research)
Source: Archives of Dermatological Research - April 1, 2024 Category: Dermatology Source Type: research

Skin color reporting in squamous cell carcinoma-related randomized controlled trials in top dermatology journals: a systematic review
The objectives are to determine the frequency that skin color is reported in randomized controlled trials (RCTs) involving squamous cell carcinoma (SCC) detection and treatment in leading dermatology journals. A systematic review of RCTs involving SCC was conducted among the top ten most impactful dermatology journals from inception to July 10th, 2023. Studies were included if they reviewed the treatment, prevention, or detection of SCC, involved patients directly and were classified as traditional RCTs. Studies were considered positive for reporting SOC if there was any demographic data in the methods or results of the fo...
Source: Archives of Dermatological Research - March 30, 2024 Category: Dermatology Source Type: research

Global burden and future trends in psoriasis epidemiology: insights from the global burden of disease study 2019 and predictions to 2030
ConclusionThis research revealed a global decline in psoriasis incidence rate from 1990 to 2019, with predictions suggesting this trend continues through 2030. Geographic disparities underscore the importance of tailored healthcare policies. (Source: Archives of Dermatological Research)
Source: Archives of Dermatological Research - March 26, 2024 Category: Dermatology Source Type: research