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Systematic evaluation of Merkel cell carcinoma clinical practice guidelines using the AGREE II instrument
The objective of this study was to appraise such CPGs via the Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument. Eight CPGs were identified via systematic literature search following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. Four appraisers trained in AGREE II protocols evaluated each CPG and deemed two CPGs as high quality, five as moderate quality, and one as low quality. Intraclass correlation coefficients (ICCs) were calculated to verify reviewer consistency as excellent, good, and moderate across four, one, and one domain, respectively. The majority o...
Source: Archives of Dermatological Research - April 25, 2024 Category: Dermatology Source Type: research

Effectiveness of atopic dermatitis patient education programs – a systematic review and meta-analysis
In this study, we conducted a systematic review of the literature to determine the effectiveness of online programming in AD education compared to in-person interventions. A comprehensive search was conducted in accordance with the Cochrane Handbook for Systematic Reviews of Interventions 2019. Studies were retrieved based on articles published up to 04 April 2023. Adherence to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) Statement guided the reportage process for this systematic review and meta-analysis. The primary outcome of our meta-analysis was the effect of various educational modali...
Source: Archives of Dermatological Research - April 25, 2024 Category: Dermatology Source Type: research

Cytokine signaling pathways as molecular markers of the efficacy of phototherapy in early stages of mycosis fungoides
(Source: Archives of Dermatological Research)
Source: Archives of Dermatological Research - April 25, 2024 Category: Dermatology Source Type: research

Investigating the link between rosacea and neurological diseases: an all of us case-control study
(Source: Archives of Dermatological Research)
Source: Archives of Dermatological Research - April 25, 2024 Category: Dermatology Source Type: research

Transcriptional variations at perilesional site in vitiligo patients: probably a fight for cell-survival
AbstractExploration of gene expression variations is a potential source to unravel biological pathways involved in pathological changes in body and understand the mechanism underneath. Vitiligo patients were explored for gene expression changes transcriptionally at perilesional site in comparison to normal site of same patients for melanogenesis pathway (TYR, DCT& TYRP1) cell adhesion (MMPs& TIMP1), cell survival (BCL2& BAX1) as well as proliferation, migration& development (SOX9, SOX10& MITF) regulatory system, using skin biopsy samples. Results were also compared with changes in gene expression for me...
Source: Archives of Dermatological Research - April 25, 2024 Category: Dermatology Source Type: research

Skin of color representation of skin cancer is minimal on the internet: a Google images search analysis
(Source: Archives of Dermatological Research)
Source: Archives of Dermatological Research - April 25, 2024 Category: Dermatology Source Type: research

Bimekizumab in psoriasis: a monocentric study evaluating short- and mid-term effectiveness and safety profile in a real-world setting
ConclusionOur results confirm that this IL17A/F inhibitor is highly effective, with a tolerability profile similar to the one expected from RCTs. (Source: Archives of Dermatological Research)
Source: Archives of Dermatological Research - April 25, 2024 Category: Dermatology Source Type: research

Evaluating the inpatient burden of antimicrobial resistance in hidradenitis suppurativa hospitalizations: a cross-sectional analysis
(Source: Archives of Dermatological Research)
Source: Archives of Dermatological Research - April 25, 2024 Category: Dermatology Source Type: research

Diagnostic discordance of Stevens-Johnson syndrome and toxic epidermal necrolysis between dermatologists and primary inpatient teams: a single-institution retrospective chart review
(Source: Archives of Dermatological Research)
Source: Archives of Dermatological Research - April 25, 2024 Category: Dermatology Source Type: research

Use of complementary and alternative medicine in vitiligo: a cross-sectional survey
AbstractVitiligo is characterized by skin depigmentation, which can lead to profound psychological effects and decreased quality of life, especially for those with skin of color. Individuals with vitiligo may utilize complementary and alternative medicine (CAM) due to limited treatment options with varying efficacy.An anonymous, multiple-choice, cross-sectional questionnaire was distributed to participants with vitiligo in the United States through online forums. Data on disease characteristics, use of prescription medications, use of topical therapies, supplements, and diets, and perceptions of CAM were collected.In total...
Source: Archives of Dermatological Research - April 23, 2024 Category: Dermatology Source Type: research

Understanding patient perspectives on vaccine decision making in adults with autoimmune bullous diseases: a qualitative study
AbstractPatients with autoimmune bullous diseases are at an increased risk of infection, both from the underlying skin disease and from immunosuppressive treatments. Limited information is available on vaccine beliefs and behaviors in dermatology patients and adults with autoimmune bullous diseases in particular. To understand vaccine decision making, identify perceived risks and benefits of vaccinations, and discuss individual experiences in patients with autoimmune bullous diseases in the United States. A qualitative study was performed utilizing semi-structured interviews, and analysis was conducted on NVivo. Patterns w...
Source: Archives of Dermatological Research - April 18, 2024 Category: Dermatology Source Type: research

The potential role of tumor necrosis factor- α in thrombosis in livedoid vasculopathy
(Source: Archives of Dermatological Research)
Source: Archives of Dermatological Research - April 18, 2024 Category: Dermatology Source Type: research

Understanding patient perspectives on vaccine decision making in adults with autoimmune bullous diseases: a qualitative study
AbstractPatients with autoimmune bullous diseases are at an increased risk of infection, both from the underlying skin disease and from immunosuppressive treatments. Limited information is available on vaccine beliefs and behaviors in dermatology patients and adults with autoimmune bullous diseases in particular. To understand vaccine decision making, identify perceived risks and benefits of vaccinations, and discuss individual experiences in patients with autoimmune bullous diseases in the United States. A qualitative study was performed utilizing semi-structured interviews, and analysis was conducted on NVivo. Patterns w...
Source: Archives of Dermatological Research - April 18, 2024 Category: Dermatology Source Type: research

The potential role of tumor necrosis factor- α in thrombosis in livedoid vasculopathy
(Source: Archives of Dermatological Research)
Source: Archives of Dermatological Research - April 18, 2024 Category: Dermatology Source Type: research