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Condition: Autoimmune Disease

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Total 584 results found since Jan 2013.

The role of IL-23/IL-17 axis in ischemic stroke from the perspective of gut-brain axis
Neuropharmacology. 2023 Mar 14:109505. doi: 10.1016/j.neuropharm.2023.109505. Online ahead of print.ABSTRACTBidirectional communication between central nervous system (CNS) and intestine is mediated by nerve, endocrine, immune and other pathways in gut-brain axis. Many diseases of CNS disturb the homeostasis of intestine and gut microbiota. Similarly, the dysbiosis of intestinal and gut microbiota also promotes the progression and deterioration of CNS diseases. IL-23/IL-17 axis is an important inflammatory axis which is widely involved in CNS diseases such as experimental autoimmune encephalomyelitis (EAE), multiple sclero...
Source: Neuropharmacology - March 16, 2023 Category: Drugs & Pharmacology Authors: Yang Jiang Yajie Dai Zhenquan Liu Yan Liao Shuyong Sun Xianghe Kong Jingjing Hu Yibo Tang Source Type: research

Idiopathic pulmonary hemosiderosis and stroke secondary to protein C deficiency in a child with Down syndrome: a case report
ConclusionIdiopathic pulmonary hemosiderosis remains a severe disease, which is rarely associated with Down syndrome. The management of this disease in Down syndrome patients is difficult, especially when associated with an ischemic stroke secondary to protein C deficiency.
Source: Journal of Medical Case Reports - March 11, 2023 Category: General Medicine Source Type: research

Future-proofing the Profession: Physiotherapists ’ Perceptions of their Current and Emerging Role
This qualitative report is important and reflects the deeper thinking that is needed about the directions of physiotherapy as a leading established health profession [1]. As a profession we have shown less reflexivity and responsiveness to epidemiologic trends since the end of World War 2, over 70 years ago. Given the progressive increase in prevalence of chronic lifestyle-related non-communicable diseases since World War 2, namely, heart disease, cancer, hypertension, stroke, diabetes, obesity, renal disease, autoimmune diseases, and Alzheimer ’s disease and that non-invasive interventions are typically superior to drug...
Source: Physiotherapy - March 7, 2023 Category: Physiotherapy Authors: Elizabeth Dean Tags: Letter to the Editor Source Type: research

Dietary energy restriction in  neurological diseases: what’s new?
AbstractEnergy-restricted diet is a specific dietary regimen, including the continuous energy-restricted diet and the intermittent energy-restricted diet. It has been proven effective not only to reduce weight and extend the lifespan in animal models, but also to regulate the development and progression of various neurological diseases such as epilepsy, cerebrovascular diseases (stroke), neurodegenerative disorders (Alzheimer's disease and Parkinson's disease) and autoimmune diseases (multiple sclerosis). However, the mechanism in this field is still not clear and a systematic neurological summary is still missing. In this...
Source: European Journal of Nutrition - February 26, 2023 Category: Nutrition Source Type: research

Nasu-Hakola Disease With Stroke-like Attack: A Case Report
Alzheimer Dis Assoc Disord. 2023 Feb 20. doi: 10.1097/WAD.0000000000000547. Online ahead of print.ABSTRACTHomozygous mutations in the triggering receptor expressed on myeloid cells 2 (TREM2) gene are known to cause Nasu-Hakola disease, which is a rare cause of progressive presenile dementia. A 36-year-old woman presented with repetitive seizures, a 5-year history of progressive behavioral and cognitive changes, and an affected sibling. Magnetic resonance imaging of the brain revealed an ischemic lesion in the left medial temporal lobe. Extensive evaluation of juvenile stroke revealed that viral and autoimmune encephalitide...
Source: Alzheimer Disease and Associated Disorders - February 23, 2023 Category: Psychiatry Authors: Azra Rashid Nezhad Nahid Olfati Ali Shoeibi Fariborz Rezaei Talab Mohsen Soltani Sabi Source Type: research

Giant Cell Arteritis Presenting with Mania, Psychosis, and Cognitive Dysfunction: A Case Report
CONCLUSION: Corticosteroids led to a temporary exacerbation of manic symptoms, which improved after 3 to 4 weeks of continuous treatment, indicating that the symptoms were most likely associated with GCA. The patient manifested with clinical features and a clinical course that has, to our knowledge, not been described or published before. Therefore, GCA may be an underdiagnosed disease in psychiatric populations and should be considered in case of atypical, new-onset psychiatric disorders in the elderly.PMID:36819979 | PMC:PMC9938786 | DOI:10.1155/2023/7989712
Source: Case Reports in Psychiatry - February 23, 2023 Category: Psychiatry Authors: Heidi Madeleine Latvala Solveig Kl æbo Reitan Arne Einar Vaaler Source Type: research

Nasu-Hakola Disease With Stroke-like Attack: A Case Report
Alzheimer Dis Assoc Disord. 2023 Feb 20. doi: 10.1097/WAD.0000000000000547. Online ahead of print.ABSTRACTHomozygous mutations in the triggering receptor expressed on myeloid cells 2 (TREM2) gene are known to cause Nasu-Hakola disease, which is a rare cause of progressive presenile dementia. A 36-year-old woman presented with repetitive seizures, a 5-year history of progressive behavioral and cognitive changes, and an affected sibling. Magnetic resonance imaging of the brain revealed an ischemic lesion in the left medial temporal lobe. Extensive evaluation of juvenile stroke revealed that viral and autoimmune encephalitide...
Source: Alzheimer Disease and Associated Disorders - February 23, 2023 Category: Psychiatry Authors: Azra Rashid Nezhad Nahid Olfati Ali Shoeibi Fariborz Rezaei Talab Mohsen Soltani Sabi Source Type: research

Giant Cell Arteritis Presenting with Mania, Psychosis, and Cognitive Dysfunction: A Case Report
CONCLUSION: Corticosteroids led to a temporary exacerbation of manic symptoms, which improved after 3 to 4 weeks of continuous treatment, indicating that the symptoms were most likely associated with GCA. The patient manifested with clinical features and a clinical course that has, to our knowledge, not been described or published before. Therefore, GCA may be an underdiagnosed disease in psychiatric populations and should be considered in case of atypical, new-onset psychiatric disorders in the elderly.PMID:36819979 | PMC:PMC9938786 | DOI:10.1155/2023/7989712
Source: Case Reports in Psychiatry - February 23, 2023 Category: Psychiatry Authors: Heidi Madeleine Latvala Solveig Kl æbo Reitan Arne Einar Vaaler Source Type: research