A Case of Complex Partial Seizures Presenting as Acute and Transient Psychotic Disorder.
Conclusion: Patients presenting with psychosis need careful diagnostic evaluation for other possibilities. PMID: 31186974 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - June 14, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Executive Dysfunction and Language Deficits in a Pediatric Patient with OCD and MDD with Suicidality.
We report the case of a 16-year-old girl who presented with bizarre, intrusive suicidal thoughts in the setting of OCD and MDD. This case is unusual in that we have accurate neuropsychological determination of our patient's language and executive function deficits, and we propose a link between them and her expression of suicidality in the context of OCD and MDD. PMID: 31183239 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - June 12, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Criminal Behaviour Associated with a Novel Mutation in the VPS13A-Gene Causing Chorea-Acanthocytosis.
Authors: Elmgreen SB Abstract Heralded by obsessive-compulsive disorder and anxiety, chorea-acanthocytosis may initially present in a psychiatric setting. As insidious onset of involuntary movements is commonly precipitated by dopamine blocking agents, this may not prompt further neurological investigation until symptoms progress after withdrawal of the suspected offending drug. Oromandibular dystonia and frontal disinhibition should call for early neurologic evaluation. PMID: 31139485 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - May 30, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Use of ECT in Major Vascular Neurocognitive Disorder with Treatment-Resistant Behavioral Disturbance following an Acute Stroke in a Young Patient.
Authors: Rodenbach KE, Varon D, Denko T, Peterson R, Andreescu C Abstract The following case describes the utilization of bitemporal ECT as a treatment of last resort in a 47-year-old woman with profoundly treatment-resistant behavioral disturbance poststroke. The use of ECT led to improvement in symptoms sufficient for discharge from an inpatient psychiatric unit to the nursing home. Neuropsychiatric sequelae of stroke include poststroke depression, anxiety, mania, psychosis, apathy, pathological laughter and crying, catastrophic reaction, and mild and major vascular neurocognitive disorders. Behavioral disturbanc...
Source: Case Reports in Psychiatry - May 30, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Accidental Overdose of Paliperidone Palmitate.
We report the case of a 21-year-old male with a history of mental illness that presented with selective mutism, disorganized speech, thought process and behavior, and auditory hallucinations who accidentally received 624 mg Paliperidone Palmitate intramuscularly with no reported side effects after 2 weeks of monitoring and observation. Paliperidone is a D2, 5HT2A receptor antagonist with additional antagonist activity at α-1 and α-2, H-1 receptor sites, and four metabolic pathways identified for its metabolism. Studies have reported adverse effects such as acute dystonia, acute renal failure, and cardiov...
Source: Case Reports in Psychiatry - May 23, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Premature Death of a Schizophrenic Patient due to Evacuation after a Nuclear Disaster in Fukushima.
Authors: Sonoda Y, Ozaki A, Hori A, Higuchi A, Shimada Y, Yamamoto K, Morita T, Sawano T, Leppold C, Tsubokura M Abstract Although psychiatric patients are likely to be adversely impacted by disasters, information regarding the processes involved in adverse impacts is limited. In March 2011, Japan experienced an earthquake, tsunami, and the Fukushima Daiichi Nuclear Power Plant accident. In its aftermath, Takano Hospital, 22 km south of the power plant, underwent forced patient evacuation. A 54-year-old Japanese male with schizophrenia, who had been hospitalized in the psychiatric ward for over 20 years, was transf...
Source: Case Reports in Psychiatry - May 15, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Attempted Suicide in a Parkinsonian Patient Treated with DBS of the VIM and High Dose Carbidopa-Levodopa.
Discussion: With PD and DBS being associated with behavioral changes and depressive symptoms and carbidopa-levodopa therapy being linked to behavioral changes such as impulsivity, it is important that these patients be closely monitored and research analyzes how these factors may interact and lead to an increased risk of suicide. Furthermore, when symptoms appear, a clear protocol must be established on managing these patients. We therefore recommend an approach that utilizes imaging to assess any changes in DBS placement, dose management of carbidopa-levodopa, and behavior monitoring in an inpatient setting. PMID: 310...
Source: Case Reports in Psychiatry - April 30, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Neuropsychiatric Manifestations of Partial Agenesis of the Corpus Callosum: A Case Report and Literature Review.
We present the case of a patient with partial agenesis of the corpus callosum who exhibits depressed mood, transient loss of memory, and history of cognitive, social, and behavioral disturbances that developed during his childhood. Recent and pertinent literature was reviewed and the agenesis of the corpus callosum and its associated neuropsychiatric manifestations are discussed. PMID: 31019828 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - April 26, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Decreased Clostridium Abundance after Electroconvulsive Therapy in the Gut Microbiota of a Patient with Schizophrenia.
Authors: Kanayama M, Hayashida M, Hashioka S, Miyaoka T, Inagaki M Abstract Relationships between gut microbiota and various disease pathogeneses have been investigated, but those between the pathogeneses of mental illnesses, including schizophrenia, and gut microbiota have only recently attracted attention. We observed a change in the gut microbiota of a patient with schizophrenia after administering electroconvulsive therapy (ECT). A 59-year-old woman was diagnosed with schizophrenia at 17 years of age and has been taking antipsychotic drugs since the diagnosis. Clostridium, which occupied 86.5% of her bacterial ...
Source: Case Reports in Psychiatry - April 3, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Effectiveness of Kangaroo Care for a Patient with Postpartum Depression and Comorbid Mother-Infant Bonding Disorder.
Authors: Takubo Y, Nemoto T, Obata Y, Baba Y, Yamaguchi T, Katagiri N, Tsujino N, Kitamura T, Mizuno M Abstract The presently reported patient was a 37-year-old married primipara with peripartum depression comorbid with bonding disorder. Care anxiety and a lack of affection towards her baby first appeared at around the time of delivery, and the patient developed major depression at one month after the birth of her healthy baby. At first, standard treatment for major depression including the use of antidepressants, electroconvulsive therapy, and supportive psychotherapy were provided. However, bonding problems appea...
Source: Case Reports in Psychiatry - April 3, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Isoniazid-Induced Acute Psychosis in a Patient with Pleural Tuberculosis.
We describe the case of a 21-year-old black woman, with no prior psychiatric history, who developed a psychotic episode four days after she was started on isoniazid. This case highlights psychosis arising as a possible adverse effect of isoniazid and the importance of remaining vigilant when antituberculous therapy is started. PMID: 30906613 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - March 26, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Persistent Idiopathic Facial Pain Associated with Somatoform Disorder in an 11-Year-Old Boy.
Authors: Sakurai Y, Fujii A, Kato F Abstract Persistent idiopathic facial pain (PIFP) is a poorly understood chronic disorder that rarely occurs in children. An 11-year-old boy initially presented with right cheek pain and a streptococcal infection 6 weeks previously. Facial cellulitis was suspected, which was resolved by antibiotic treatment. The right cheek pain recurred within 4 weeks of this initial visit. Because the antibiotic treatment did not relieve the pain, the patient visited our outpatient clinic. Physical examination revealed facial tenderness in an area that corresponded with the region supplied by t...
Source: Case Reports in Psychiatry - March 20, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Intensive Outpatient Treatment of Depression in a Spinocerebellar Ataxia Type 1 Patient.
Conclusion: Awareness among physicians, particularly psychiatrists and neurologists, regarding IOP programs as a treatment option for comorbid depression in the clinical setting of progressive SCA or other neurological conditions can be beneficial to patients requiring an increased level of psychiatric treatment. PMID: 30886755 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - March 20, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

A Case of Violent Suicide Attempt in a Context of Myxedema Psychosis following Radioiodine Treatment in a Patient with Graves' Disease.
We report a case of suicide attempt by self-stabbing in a 43-year-old woman without past psychiatric history, four months after radioiodine therapy for Graves' disease. On clinical examination remarkable signs of myxedema were found and blood investigations showed hypothyroidism with an extremely high thyroid stimulating hormone (TSH) level (152 mUI/L; reference range 0.20-5.10). The patient presented delirium symptoms at the time of self-stabbing, which was associated with persecutory delusions and auditory harm command hallucinations. A rapid physical and psychiatric improvement was observed after the initiation of an or...
Source: Case Reports in Psychiatry - February 8, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Polypharmacy Leading to Priapism in HIV Patient with Schizoaffective Disorder: A CYP450 Cascade.
Authors: Sharma V, Sharma A Abstract With increasing trend of polypharmacy, there are higher chances of drug-drug interactions leading to adverse effects, especially in psychiatric patients with co-morbid chronic medical problems. This case demonstrates a schizoaffective 30-year-old male on highly active antiretroviral therapy (HAART) who reported an incident of priapism potentially caused by an interaction between previously prescribed atypical antipsychotic, trazodone, norepinephrine dopamine reuptake inhibitor (NDRI), HAART, and newly added selective serotonin reuptake inhibitor (SSRI). This case emphasizes obta...
Source: Case Reports in Psychiatry - February 7, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Emotion Processing and the Role of Compassion in Psychotherapy from the Perspective of Multiple Selves and the Compassionate Self.
In this report, the author introduces a case in which the therapist helped a client to process emotional experiences by leading the client to pay attention to her own emotional responses. The client accessed multiple desires for each emotion and recognized the context for each. To integrate multiple desires and contexts, the therapist used multiple selves exercises from Compassion Focused Therapy. The compassionate self exercises play a role in integrating complicated emotions and in directing the client toward making an adequate choice independently. On its own, processing emotional experiences can induce adaptive and hea...
Source: Case Reports in Psychiatry - February 7, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Gastaut-Geschwind Syndrome, Faciobrachial Dystonic Seizure, and Autoimmune Limbic Encephalitis.
Authors: Benhamou OJ, Tavakkoli M, Okan H, Nobler M Abstract Here we report a case of a 55-year-old male who had presented with recent falls and behavioral changes, including a heightened religious preoccupation, hypergraphia, and paranoid ideations. He was initially treated for psychosis but soon exhibited absence-like seizures, which were consistent with faciobrachial dystonic seizures. Workup for underlying infectious, immunodeficiency, and autoimmune causes revealed antibodies towards the leucine-rich glioma inactivated subunit of the voltage-gated potassium complex. The patient was treated with steroids and in...
Source: Case Reports in Psychiatry - January 12, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Urethral Polyembolokoilamania: An Unusual Manifestation of Behavioral and Psychological Symptoms of Dementia (BPSD).
Authors: Shafi RMA, Suarez L, Lapid MI Abstract Behavioral and psychological symptoms of dementia (BPSD) have varied presentations and frequently occur throughout the trajectory of dementia. Hypersexuality and general disinhibition of societal and cultural norms are commonly documented in all types of dementia. However, sparse literature exists on polyembolokoilamania (insertion of foreign objects in bodily orifices) without a sexual component as a dementia-related symptom. We review an unusual case of a 94-year-old man who presented with urethral polyembolokoilamania without hypersexuality or other behavioral disi...
Source: Case Reports in Psychiatry - January 2, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

The Pathophysiology and Management of Coprophagia: A Report of Two Cases and Literature Review.
We present two cases of patients with coprophagia in seeking to address these questions. Common symptoms of thought content disorder related to coprophagic behavior are noted in both cases. A shorter time to resolution of coprophagia is noted in one of the patients compared to previously reported studies. Recent and pertinent literature was reviewed and the implications for diagnosis and management of coprophagia are discussed. PMID: 30581644 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - December 26, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Modafinil Induced Psychosis in a Patient with Bipolar 1 Depression.
Authors: DiSciullo AA, English CD, Horn WT Abstract Modafinil has been used as an adjunctive medication in the treatment of bipolar 1 depression with reported success. Case reports have been published demonstrating modafinil induced mania in bipolar patients and modafinil induced psychosis in schizophrenic patients. To our knowledge, we report the only case of modafinil induced psychosis in a patient with bipolar depression treated with both mood stabilizers and antipsychotics. In addition, it is the quickest onset to psychosis (2 days) at the lowest dosage of modafinil (100 mg/day) reported in the literature. Alth...
Source: Case Reports in Psychiatry - November 13, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

A Case Report of Compassion Focused Therapy (CFT) for a Japanese Patient with Recurrent Depressive Disorder: The Importance of Layered Processes in CFT.
This report presents a case of compassion focused therapy for a Japanese female with major depressive disorder and suicidal feelings. After receiving compassion focused therapy, the patient recovered and began to have social interaction with others again. This case suggested the importance of psychoeducation, exercises involving compassionate images and breathing, and a compassionate relationship in conducting compassion focused therapy. PMID: 30416837 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - November 13, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Tramadol-Induced Mood Elevation in a Patient with No Previous Psychiatric History.
We report on the observation of a distressing mood-elevating effect for tramadol in a patient with no previous psychiatric history. We present the case of a 26-year-old female patient who developed accelerated flow of speech, overactivity, and difficulty in sleeping following intake of tramadol 50 mg dose. These symptoms resolved four hours later and recurred as she retook tramadol. The patient has no history of mood disorder or any other psychiatric comorbidity. Clinicians should exercise caution when prescribing tramadol. PMID: 30364082 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - October 27, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Generalized Anxiety Disorder in Very Young Children: First Case Reports on Stability and Developmental Considerations.
Authors: Scheeringa MS, Burns LC Abstract Generalized anxiety disorder (GAD) is purported to start in early childhood but concerns about attenuation of anxiety symptoms over time and the development of emerging cognitive and emotional processing capabilities pose multiple challenges for accurate detection. This paper presents the first known case reports of very young children with GAD to examine these developmental challenges at the item level. Three children, five-to-six years of age, were assessed with the Diagnostic Infant and Preschool Assessment twice in a test-retest reliability study. One case appeared to s...
Source: Case Reports in Psychiatry - October 23, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Episodic Behavioural Regression in an 8-Year-Old Female: Sequelae of 22q11.2 Duplication Syndrome.
Authors: Bahji A, Khalid-Khan S Abstract 22q11.2 duplication syndrome is a recently discovered genetic syndrome with unclear neuropsychiatric sequelae. While its connection to 22q11.2 deletion syndrome is actively investigated, case reports on the neuropsychiatric sequelae of affected individuals have been previously described, largely focusing on comorbid autism spectrum disorder. Here, we present the case of an 8-year-old female experiencing episodes of severe behavioural regression following medical illness. We analyze the case and relate it to the available literature and identify potential risk factors. PM...
Source: Case Reports in Psychiatry - September 5, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Effects of the Attention Training Technique on Auditory Hallucinations in Schizo-Affective Disorder: A Single Case Study.
Authors: Carter KEP, Wells A Abstract A 41-year-old female with schizo-affective disorder presenting with an eight-year history of auditory hallucinations participated in a single case treatment study (A-B-A-B-A-C-B) of the effects of the Attention Training Technique (ATT). No antipsychotic medication was prescribed in this case following a serious adverse reaction in the past. The aim of the study was to test the impact of ATT on the frequency and duration of hallucinations using a repeated return to baseline followed by an alternating treatment design. The alternative intervention consisted of autogenic relaxatio...
Source: Case Reports in Psychiatry - September 5, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

A Case of Neuroleptic Malignant Syndrome in a Profoundly Intellectually Disabled Patient with Successful Reintroduction of Antipsychotic Therapy with Quetiapine.
We describe the diagnostic and treatment process leading to symptom remission. We then discuss our decision to reintroduce an atypical antipsychotic agent, quetiapine. This case illustrates the importance of early recognition of the signs and symptoms of NMS and the need to initiate treatment promptly in order to prevent complications, including death. This case also highlights the decision to resume antipsychotic pharmacotherapy after adequate resolution of NMS, demonstrating that it can be done so safely if started at low doses coupled with intensive monitoring of the patient. PMID: 30112240 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - August 17, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Periodic Catatonia Marked by Hypercortisolemia and Exacerbated by the Menses: A Case Report and Literature Review.
Authors: Zwiebel S, Villasante-Tejanos AG, de Leon J Abstract Kahlbaum first described catatonia; later Kraepelin, Gjessing, and Leonhard each defined periodic catatonia differently. A 48-year-old female with catatonia, whose grandmother probably died from it, was prospectively followed for>4 years in a US psychiatric state hospital. Through 4 catatonic episodes (one lasting 17 months) there were menstrual exacerbations of catatonia and increases in 4 biological variables: (1) creatine kinase (CK) up to 4,920 U/L, (2) lactate dehydrogenase (LDH) up to 424 U/L, (3) late afternoon cortisol levels up to 28.0 mcg/dL...
Source: Case Reports in Psychiatry - August 4, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

An Atypical Presentation of Pediatric Acute Neuropsychiatric Syndrome Responding to Plasmapheresis Treatment.
Authors: Barzman DH, Jackson H, Singh U, Griffey M, Sorter M, Bernstein JA Abstract Here we report a case of a 15-year-old female who had originally been diagnosed and treated unsuccessfully for schizophrenia, psychosis, severe anxiety, and depression. More in-depth history revealed an abrupt onset of her symptoms with remote acute infections and many exhibited characteristics of obsessive compulsive disorder with rituals. Work-up for underlying infectious, immunodeficiency, and autoimmune causes was unrevealing except for very high levels of anti-neuronal antibodies which have been linked to Pediatric Acute-onset ...
Source: Case Reports in Psychiatry - July 31, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Those Who Hear Music: Three Cases on Musical Hallucinations.
We report three patients who presented with musical hallucinations due to different aetiologies, namely, due to hearing impairment, intracerebral haemorrhage, and schizophrenia. The case series also highlights the fact that different aetiologies should be managed differently for the patients to be benefited. PMID: 30050719 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - July 31, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Management of Psychosis in a Patient with Probable Dopa-Responsive Dystonia.
This report describes a novel case of a 20-year-old male with a history of dopa-responsive dystonia and schizoaffective disorder who presented with both dystonia and psychosis after a period of medication noncompliance. This case provides a reference for the management of psychosis in patients with dopa-responsive dystonia and highlights the need for more research on the nonmotor symptoms that accompany this neurological disorder. PMID: 30013806 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - July 18, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Low-Dose Fluoxetine in Four Children with Autistic Spectrum Disorder Improves Self-Injurious Behavior, ADHD-Like Symptoms, and Irritability.
Authors: Lucchelli JP, Bertschy G Abstract Autism Spectrum Disorder (ASD) is defined by the copresence of two core symptoms: alteration in social communication and repetitive behaviors and/or restricted interests. In ASD children and adults, irritability, self-injurious behavior (SIB), and Attention Deficit and Hyperactivity Disorders- (ADHD-) like symptoms are regularly observed. In these situations, pharmacological treatments are sometimes used. Selective Serotonin Reuptake Inhibitors- (SSRI-) based treatments have been the subject of several publications: case reports and controlled studies, both of which demons...
Source: Case Reports in Psychiatry - July 15, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Diagnostic, Treatment, and System Challenges in the Management of Recurrent Neuroleptic Malignant Syndrome on a General Medical Service.
Authors: Verma K, Jayadeva V, Serrano R, Sivashanker K Abstract Neuroleptic malignant syndrome (NMS), an iatrogenic form of malignant catatonia, carries high morbidity and mortality rates especially in the context of delayed recognition and standard intervention protocol of lorazepam trial. However, there is limited guidance available through literature for further management if benzodiazepine treatment is ineffective and electroconvulsive therapy (ECT) is not readily accessible. This case report describes a multimodal approach to address the diagnostic, treatment, and logistical system challenges in an acute medic...
Source: Case Reports in Psychiatry - July 12, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Misinterpretation of Psychiatric Illness in Deaf Patients: Two Case Reports.
Authors: Anglemyer E, Crespi C Abstract The Deaf/hard of hearing population is growing rapidly and the medical community is facing a higher demand for this special needs group. The Deaf culture is unique in that spoken word is via sign language. What one person may see as mania or psychosis is actually a norm with Deaf individuals. The fear of the unknown language often creates immediate conclusions that are false. As such, being culturally sensitive becomes a large component of properly assessing a Deaf patient in any psychiatric situation. In the first case, the patient is a 26-year-old prelingually Deaf male, wh...
Source: Case Reports in Psychiatry - July 11, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Pervasive Refusal Syndrome in Autistic Spectrum Disorder.
We describe a case of PRS in a 9-year-old boy with a diagnosis of Autism Spectrum Disorder (ASD) presenting with severe weight loss due to extreme restriction of food and fluids. Other prominent symptoms included total mutism, school refusal, and self-neglect. He was admitted to a specialist Child and Adolescent Mental Health Unit. We discuss the symptoms present in this case and the differential diagnosis of ASD in PRS. Although this differential has briefly been considered one in previous case, there have been no reported cases of PRS with a prior diagnosis of ASD. We explore comorbidity and interaction of the two diagno...
Source: Case Reports in Psychiatry - July 11, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Camptocormia in an Adolescent: A Case Report and Review of the Literature.
Authors: Kaplan L, Aurigemma E, Sullivan T, Sidlow R Abstract Camptocormia, or bent-spine syndrome, is an entity with a long history and many etiologies. We discuss below both the history of this diagnosis in light of a rare case of psychogenic camptocormia and the recent changes in nosology regarding this disorder. PMID: 29971176 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - July 5, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Delayed-Onset Seizure in a Mild Quetiapine Overdose: Report of a Case and Review of the Literature.
Authors: Chen JA, Unverferth KM, Cheung EH Abstract Among atypical antipsychotics, quetiapine is commonly prescribed and considered to have a favorable side effect and safety profile. Here, we report the case of a patient who developed a generalized tonic-clonic seizure 28 hours following ingestion of 1,400 mg of quetiapine. Review of the literature identifies delayed-onset seizure as a potential complication of quetiapine overdose. Unique to this case, delayed-onset seizures occurred in a patient with a relatively low dose of quetiapine and no obvious toxidrome, suggesting that this reaction may be an impor...
Source: Case Reports in Psychiatry - June 13, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Salivary Alpha-Amylase Activity Levels in Catatonic Schizophrenia Decrease after Electroconvulsive Therapy.
Conclusions: sAA activity levels could be a potential biomarker of schizophrenia with catatonic state. PMID: 29862108 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - June 5, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Phenibut ( β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: Emerging Nootropics of Abuse.
We report a case in which a patient experienced withdrawal symptoms from phenibut and was successfully treated with a baclofen taper. This case report highlights the development of phenibut use disorder with coingestion of alcohol and potential management for phenibut withdrawal. We believe clinicians must be aware of how phenibut dependence may present and how to manage the withdrawal syndrome. PMID: 29854531 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - June 3, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Treatment-Emergent Mania in a Prepubertal Boy.
We present the case of a prepubertal child presenting with an apparent depressive episode who developed treatment-emergent mania when commenced on sertraline. This case highlights the need for further research into the presentations and pharmacological management of prepubertal children with bipolar affective disorder. PMID: 29850349 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - June 1, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Olfactory Reference Syndrome with Suicidal Attempt Treated with Pimozide and Fluvoxamine.
Authors: Jegede O, Virk I, Cherukupally K, Germain W, Fouron P, Olupona T, Jolayemi A Abstract The core symptomatology of the Olfactory Reference Syndrome (ORS) is characterized by a preoccupation with the belief that one emits an offensive odor, albeit not perceived by others. The present case is that of a 75-year-old African American woman, with an unclear past psychiatric history, who was brought into our Emergency Room after a suicide attempt. The patient reported a three-year history of a "rotten" smell from her vagina. She adamantly believes that she smells despite being told otherwise by people. Th...
Source: Case Reports in Psychiatry - June 1, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

"Capgras" Delusions Involving Belongings, Not People, and Evolving Visual Hallucinations Associated with Occipital Lobe Seizures.
We present, to our knowledge, the first reported case of visual hallucinations and Capgras delusions for objects that developed secondary to new onset occipital lobe epilepsy. We then discuss the possible underlying neurologic mechanisms responsible for the symptomatology. PMID: 29707400 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - May 2, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Polysubstance and Behavioral Addictions in a Patient with Bipolar Disorder: Role of Lifetime Subthreshold Autism Spectrum.
Authors: Dell'Osso L, Conversano C, Corsi M, Bertelloni CA, Cremone IM, Carpita B, Carbone MG, Gesi C, Carmassi C Abstract This case report draws attention to the potential relevance of undetected autism spectrum symptoms in a bipolar patient with high work functioning showing a peculiar addictive profile with impulsive and antisocial behaviors. A 23-year-old man with a diagnosis of Bipolar Disorder (BD) and Substance Use Disorder (SUD) was hospitalized at the Psychiatric Clinic of the University of Pisa for diuretics and β-2 adrenergic agonist abuse in a remission phase of benzodiazepines and substance abuse....
Source: Case Reports in Psychiatry - April 25, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Corrigendum to "A Case of Sporadic Creutzfeldt-Jakob Disease Presenting as Conversion Disorder".
Corrigendum to "A Case of Sporadic Creutzfeldt-Jakob Disease Presenting as Conversion Disorder". Case Rep Psychiatry. 2018;2018:3826863 Authors: Yegya-Raman N, Aziz R, Schneider D, Tobia A, Leitch M, Nwobi O Abstract [This corrects the article DOI: 10.1155/2017/2735329.]. PMID: 29682384 [PubMed - in process] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - April 25, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

What Can Happen When Postpartum Anxiety Progresses to Psychosis? A Case Study.
Authors: Pirec V Abstract This case report describes a primipara without documented psychiatric history prior to complicated delivery. Onset of severe insomnia and anxiety was right after childbirth but not treated. Obsessive thinking pattern became more prominent. The patient became depressed and sought psychiatric help four months after delivery. Insomnia was then treated pharmacologically. Anxiety and depression persisted, suicidal ideation emerged, and the patient became confused, indecisive, overwhelmed, and delusional regarding her child's health. Medications for depression and anxiety were started six months...
Source: Case Reports in Psychiatry - April 22, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Huntington's Disease in a Patient Misdiagnosed as Conversion Disorder.
We present a clinical case of a 65-year-old woman admitted to our Psychiatric Acute Unit. During the 6 years preceding the admission, the patient had clinical assessments made several times by different specialties that focused only on isolated symptoms, disregarding the syndrome as a whole. In the course of her last admission, the patient was referred to our Neuropsychiatric Team, which made the provisional diagnosis of late-onset Huntington's disease, later confirmed by genetic testing. This clinical vignette highlights the importance of a multidisciplinary approach to atypical clinical presentations and raises awareness...
Source: Case Reports in Psychiatry - April 21, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Prosopagnosia as a Type of Conversion Disorder.
Conclusions: We propose that our patient's adverse childhood experiences led to the development of a particular personality and coping style that "primed" him for a later abnormal emotional and behavioural response when confronted with reminders of his traumatic background. Further interdisciplinary studies are required to further elucidate the neurobiological basis for this condition. PMID: 29666739 [PubMed] (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - April 19, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Treatment of Acute Psychosis with Second-Generation Antipsychotics in a Patient with Left Temporal Lobe Lesion.
We present a case of rapid onset severe psychosis followed by suicide attempt in a United States Navy sailor. Investigation revealed a left temporal lobe brain mass suspicious for low-grade glioma. After hospitalization and medical management with olanzapine and lurasidone the patient's psychosis improved. The purpose of this paper is to add to the existing case reports that suggest a relationship between temporal lobe lesions and psychiatric illness, specifically psychosis. In addition, this case adds insight into the effectiveness of medical therapy for brain tumor patients that are not immediate candidates for neurosurg...
Source: Case Reports in Psychiatry - April 19, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Response after Infection-Associated Rise in Clozapine Levels in Treatment-Resistant Schizoaffective Disorder.
Authors: Grootendorst-van Mil NH, Huiskens ARM, Dieleman S, Birkenhäger TK Abstract The clinical management of patients with treatment-resistant psychotic disorders is still challenging despite years of extensive research. If first-line antipsychotic treatment proves ineffective, clozapine is considered golden standard. Herein, we report on a patient with schizoaffective disorder that initially showed no response to treatment with clozapine and ECT and therefore reached a therapeutic dead end. After an unintentional exposure to supratherapeutic clozapine levels, related to a pneumonia, a significant and persis...
Source: Case Reports in Psychiatry - April 8, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Pantoprazole-Induced Delirium: Review of a Case and Associated Literature.
We present a case report of PPI-induced delirium, regarding which not much has been written in the literature. Case Report: We present a case of a 93-year-old woman with no known past psychiatric history, who was hospitalized for syncope workup and who developed delirium after a double dose of pantoprazole. Discussion: Very few reports of PPI-induced delirium exist in the literature. In this case report, we attempt to highlight the mechanism of PPI induced delirium which in our case was most likely due to the primary effects of PPI and drug-drug interactions. Given the paucity of literature on this topic, we encour...
Source: Case Reports in Psychiatry - March 18, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Reversible Thrombocytopenia after Gabapentin in an HIV-Positive Patient.
Authors: Basith M, Francis A, Bellon A Abstract Gabapentin has become increasingly used in psychiatric practice specifically for anxiety disorders. Even though gabapentin is not approved by the US Food and Drug Administration to treat anxiety, physicians sometimes use it as an alternative to benzodiazepines in patients with a history of substance abuse. Gabapentin is also prescribed when individuals are at risk of thrombocytopenia which is not considered a side effect. Among patients at risk of thrombocytopenia are those positive for human immunodeficiency virus (HIV). Here we present a case of an HIV-positive man ...
Source: Case Reports in Psychiatry - March 18, 2018 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research