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Condition: Autoimmune Disease
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Total 584 results found since Jan 2013.
Impact of Major Depressive Disorder on Comorbidities: A Systematic Literature Review
Conclusions: The presence of MDD was identified as a risk factor for both the development and the worsening of a range of comorbidities. These results highlight the importance of addressing depression early in its course and the need for integrating mental and general health care.PMID:36264099 | DOI:10.4088/JCP.21r14328
Source: Journal of Clinical Psychiatry - October 20, 2022 Category: Psychiatry Authors: Alix M Arnaud Teri S Brister Ken Duckworth Phyllis Foxworth Tonya Fulwider Ellison D Suthoff Brian Werneburg Izabela Aleksanderek Marcia L Reinhart Source Type: research
A network-based approach for isolating the chronic inflammation gene signatures underlying complex diseases towards finding new treatment opportunities
Complex diseases are associated with a wide range of cellular, physiological, and clinical phenotypes. To advance our understanding of disease mechanisms and our ability to treat these diseases, it is critical to delineate the molecular basis and therapeutic avenues of specific disease phenotypes, especially those that are associated with multiple diseases. Inflammatory processes constitute one such prominent phenotype, being involved in a wide range of health problems including ischemic heart disease, stroke, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease, and autoimmune and neurodege...
Source: Frontiers in Pharmacology - October 12, 2022 Category: Drugs & Pharmacology Source Type: research
Bilateral ballism as limb-shaking transient ischemic attacks treated with unilateral carotid artery stent placement
A man in his 80s with no medical history and a heavy smoking habit experienced a sudden involuntary movement of the bilateral limbs, trunk, and tongue. He had mild dysarthria, and could not eat (Video 1). Symptoms lasted for several hours and days, with frequent onset during the day. No consciousness impairments, paralysis, or sensory disturbances were observed. Physical examination and laboratory data did not indicate meningitis, encephalitis, post-infectious causes, or autoimmune disorders.The electroencephalogram showed no abnormalities.
Source: Journal of Stroke and Cerebrovascular Diseases - September 23, 2022 Category: Neurology Authors: Toshihiko Shimizu, Keiko Haro, Masahiko Tagawa, Masaaki Hirata, Sachiko Iwano, Hiroshi Kosaka, Yuji Yamamoto Tags: Case Report Source Type: research
Predictors of Intensive Care Unit Admission in Patients with Confirmed Coronavirus Disease 2019: A Cross-Sectional Study
CONCLUSION: A high index of suspicion for ICU admission should be maintained in patients with positive clinical and laboratory predictive factors.PMID:36117577 | PMC:PMC9445874 | DOI:10.30476/IJMS.2021.89916.2068
Source: Atherosclerosis - September 19, 2022 Category: Cardiology Authors: Naeimehossadat Asmarian Farid Zand Parvin Delavari Vahid Khaloo Zahra Esmaeilinezhad Golnar Sabetian Yaldasadat Moeini Mohsen Savaie Fatemeh Javaherforooshzadeh Farhad Soltani Farid Yousefi Ebrahim Heidari Sardabi Maryam Haddadzadeh Shoushtari Anoush Dehn Source Type: research
Emerging role of neutrophil extracellular traps in the complications of diabetes mellitus
Front Med (Lausanne). 2022 Aug 23;9:995993. doi: 10.3389/fmed.2022.995993. eCollection 2022.ABSTRACTImmune dysfunction is widely regarded as one of the central tenants underpinning the pathophysiology of diabetes mellitus (DM) and its complications. When discussing immunity, the role of neutrophils must be accounted for: neutrophils are the most abundant of the circulating immune cells and are the first to be recruited to sites of inflammation, where they contribute to host defense via phagocytosis, degranulation, and extrusion of neutrophil extracellular traps (NETs). NETs are composed of DNA associated with nuclear and c...
Source: Atherosclerosis - September 9, 2022 Category: Cardiology Authors: Areez Shafqat Saleha Abdul Rab Osama Ammar Sulaiman Al Salameh Anas Alkhudairi Junaid Kashir Khaled Alkattan Ahmed Yaqinuddin Source Type: research
Risk factors and characteristics of ischemic stroke in patients with immune thrombocytopenia: A retrospective cohort study
Immune thrombocytopenia (ITP), also known as idiopathic thrombocytopenic purpura, is an autoimmune disease characterized by a platelet count of
Source: Journal of Stroke and Cerebrovascular Diseases - August 31, 2022 Category: Neurology Authors: Xi Rong, Lidan Jiang, Meijie Qu, Shaonan Yang, Kun Wang, Liwei Jiang Source Type: research
Sex differences in comorbidities associated with Sj ögren's disease
CONCLUSIONS: The top comorbidities in Sjögren's disease were fibromyalgia, depression, and pain. Women with Sjögren's disease had a higher relative risk of developing fibromyalgia, depression, pain, migraine, hypermobile syndrome, EDS and other rheumatic autoimmune diseases. Men with Sjögren's disease had higher risk of developing cardiovascular diseases.PMID:35991633 | PMC:PMC9387724 | DOI:10.3389/fmed.2022.958670
Source: Atherosclerosis - August 22, 2022 Category: Cardiology Authors: Katelyn A Bruno Andrea Carolina Morales-Lara Edsel B Bittencourt Habeeba Siddiqui Gabriella Bommarito Jenil Patel John M Sousou Gary R Salomon Rinald Paloka Shelby T Watford David O Hodge Scott M Lieberman Todd D Rozen Paldeep S Atwal Peter T Dorsher Lyns Source Type: research
Neurosarcoidosis Presenting with Prominent Periventricular White-Matter Lesions during Steroid Treatment for Autoimmune Hepatitis
A 63-year-old woman under treatment of autoimmune hepatitis presented with headache, memory loss, and somnolence. Three months before admission, the patient experienced liver inflammation relapse after prednisolone (PSL) cessation. Consequently, PSL was resumed and then tapered. Cerebrospinal fluid (CSF) examination showed lymphocytic pleocytosis with remarkably reduced glucose and elevated angiotensin-converting enzyme and soluble interleukin-2 receptor levels. Magnetic resonance imaging (MRI) revealed prominent bilateral periventricular white-matter lesions, hydrocephalus, ischemic stroke with gadolinium enhancement of f...
Source: Case Reports in Neurology - August 19, 2022 Category: Neurology Source Type: research
Cardiology co-management of rheumatoid arthritis patients with coronary artery disease as an intervention reduces hospitalization rates and adverse event occurrence
ConclusionPatients with regular cardiology follow-up demonstrated fewer cardiac-related adverse events. This suggests that co-management may have a role in adverse cardiac event risk reduction and should therefore be an early consideration.Key Points•Rheumatoid arthritis patients demonstrate higher rates of coronary disease compared to the general population. Traditional cardiac risk factors may not be entirely responsible for this phenomenon•Hospitalization rates and adverse event occurrence are significantly higher in patients with single-provider care (rheumatology only) compared to dual provider care (rheumatology ...
Source: Clinical Rheumatology - August 16, 2022 Category: Rheumatology Source Type: research
Science Saturday: Do environmental exposures contribute to human diseases?
An accumulation of environmental chemicals, pollutants, microbes, and particulates may be living inside each of us — acquired from the air we breathe, the food we eat, products we touch, and the water we drink. These sometimes-harmful exposures can potentially interact with our genes to fuel diseases, including cancer, cardiovascular disease, respiratory illnesses, autoimmune diseases, and stroke. Research sh ows environmental factors are associated with more than 80% of human diseases and nearly 1 in 6 deaths worldwide. …
Source: News from Mayo Clinic - August 13, 2022 Category: Databases & Libraries Source Type: news
