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Drug: Acetylcysteine

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Total 2370 results found since Jan 2013.

Effect of MetioNac ® in patients with metabolic syndrome who are at risk of metabolic dysfunction associated fatty liver disease: a randomized controlled trial
CONCLUSION: supplementation with MetioNac® may be protective against hyperlipidemia, insulin resistance, and overweight among metabolic syndrome patients. Further studies on this issue are needed in a larger population.PMID:37409712 | DOI:10.20960/nh.04635
Source: Nutricion Hospitalaria - July 6, 2023 Category: Nutrition Authors: Elena Garicano Vilar Sara Sanz Rojo Sara L ópez Oliva Silvia Mart ínez Ana Terr én Lora Ismael San Mauro Martin Source Type: research

D- β-Hydroxybutyrate Dehydrogenase Mitigates Diabetes-Induced Atherosclerosis through the Activation of Nrf2
CONCLUSION: Bdh1 attenuates AS in Apoe-/- mice with type 2 diabetes, accelerates lipid degradation, and reduces lipid levels by promoting ketone body metabolism. Moreover, it activates the Nrf2 pathway of Raw264.7 by regulating the metabolic flux of fumarate, which inhibits oxidative stress and leads to a decrease in ROS and inflammatory factor production.PMID:37399841 | DOI:10.1055/s-0043-1770985
Source: Atherosclerosis - July 3, 2023 Category: Cardiology Authors: Jie Lin Qian Ren Fanjie Zhang Jing Gui Xin Xiang Qin Wan Source Type: research

Reactive oxygen species-mediated endoplasmic reticulum stress contributes to osteocyte death induced by orthodontic compressive force
This study first proposes the ERS pathway as a new potential pathway for regulating the rate of OTM based on osteocyte death. RESEARCH HIGHLIGHTS: The orthodontic force increases osteocyte death in rat alveolar bone. The compressive force causes osteocyte apoptosis by the endoplasmic reticulum stress (ERS) pathway in vitro. The ROS scavenger NAC blocked compressive force-induced ERS and osteocyte apoptosis.PMID:37382312 | DOI:10.1002/jemt.24382
Source: Cell Research - June 29, 2023 Category: Cytology Authors: Ming Yan Yun Zhang Wanting Niu Kezhou Liu Lingyun Xue Kexin Zhou Source Type: research

Integrating network pharmacology and pharmacological evaluation to reveal the therapeutic effects and potential mechanism of S-allylmercapto-N-acetylcysteine on acute respiratory distress syndrome
In conclusion, our research presented the efficacy of ASSNAC against ARDS. Furthermore, the mechanism of ASSNAC on ARDS was clarified by combining network pharmacology prediction with experimental confirmation.PMID:37369159 | DOI:10.1016/j.intimp.2023.110516
Source: International Immunopharmacology - June 27, 2023 Category: Allergy & Immunology Authors: Jinglong Wang Huatian Yang Dandan Zheng Yueyue Sun Lulu An Genju Li Zhongxi Zhao Source Type: research