What the pediatric nurse needs to know about the Impella cardiac assist device
Perfusion. 2024 Apr;39(1_suppl):95S-106S. doi: 10.1177/02676591241237761.ABSTRACTBackground: Cardiogenic shock in children still carries a high mortality risk despite advances in medical therapy. The use of temporary mechanical circulatory supports is an accepted strategy to bridge patients with acute heart failure to recovery, decision, transplantation or destination therapy. These devices are however limited in children and extracorporeal membrane oxygenation (ECMO) remains the most commonly used device. Veno-arterial ECMO may provide adequate oxygen delivery, but it does not significantly unload the left ventricle, and ...
Source: Perfusion - April 23, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Giorgia Borrelli Ilaria Nittolo Chiara Bochicchio Laura Trainelli Valerio Confalone Tiziana Satta Federica Cancani Richard Kirk Antonio Amodeo Matteo Di Nardo Source Type: research
Pediatric Diffuse Leptomeningeal Glioneuronal Tumors: Diagnosis, Follow-up and Treatment Options
CONCLUSION: Further work with larger cohorts is required to determine a common algorithm for DLGNT treatment and follow-up. This analysis may keep this entity in mind in patients with pediatric communicating hydrocephalus and may present insight into diagnosis, follow-up, and treatment options.PMID:38650559 | DOI:10.5137/1019-5149.JTN.43742-23.2 (Source: Turkish Neurosurgery)
Source: Turkish Neurosurgery - April 23, 2024 Category: Neurosurgery Authors: Ali Ozen Bahattin Tanrikulu Ayca Ersen Danyeli Memet Ozek Source Type: research
Percutaneous Ventriculoatrial Shunting as a Salvage Method in the Pediatric Hydrocephalus Patients with Peritoneal Problems
CONCLUSION: Percutaneous ventriculoatrial shunting under the guidance of intraoperative fluoroscopy and ultrasound is a safe, effective, and easy alternative in patients with peritoneal complications and a history of multiple operations.PMID:38650557 | DOI:10.5137/1019-5149.JTN.43472-23.2 (Source: Turkish Neurosurgery)
Source: Turkish Neurosurgery - April 23, 2024 Category: Neurosurgery Authors: Kadir Oktay Sinan Sozutok Umur Anil Pehlivan Dogu Cihan Yildirim Mevlana Akbaba Kerem Mazhar Ozsoy Nuri Eralp Cetinalp Source Type: research
Characterization of Ceftriaxone-Resistant < em > Haemophilus influenzae < /em > Among Korean Children
CONCLUSION: The emergence of ceftriaxone-resistant H. influenzae with ceftriaxone MIC values of up to 0.75 mg/L was observed even in children in South Korea, with most associated with S385T and L389F substitutions. The N526K mutation alone does not significantly impact ceftriaxone resistance. Further large-scale studies are essential to investigate changes in antibiotic resistance patterns and factors influencing antibiotic resistance in H. influenzae isolated from pediatric patients in Korea.PMID:38651222 | DOI:10.3346/jkms.2024.39.e136 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 23, 2024 Category: Biomedical Science Authors: Sanghoon Lee Gahee Kim Jung Hwa Kim Mi-Na Kim Jina Lee Source Type: research
Delta-S-Cys-Albumin as a Marker of Pediatric Biospecimen Integrity
We report application of a previously developed assay in adults-the ΔS-Cys-Albumin assay, which facilitates estimation of plasma and serum exposure to thawed conditions-to a population of pediatric EDTA plasma samples from patients aged 3-18 years to determine the assay's applicability, estimate its reference range for pediatric samples, and assess the impact of pre-centrifugation delay at 0°C. In addition, the effect of plasma thawed-state exposure to a range of times at 23°C, 4°C, and -20°C on ΔS-Cys-Albumin was evaluated. Using 98 precollected and processed pediatric EDTA plasma specimens, no difference was found ...
Source: Biopreservation and Biobanking - April 23, 2024 Category: Biomedical Science Authors: Schuyler Kremer Valentina Shakhnovich Amanda K Riffel Lisa Harvey Chad R Borges Source Type: research
Analyzing the Quality of Life in Individuals with Fragile X Syndrome in Relation to Sleep and Mental Health
This study included 119 individuals with Fragile X Syndrome who were given different cognitive examinations by a neuropsychologist or by parent-proxy questionnaires. This study focused on the Pediatric Quality of Life Inventory (PedsQoL), the Anxiety, Depression and Mood Scale (ADAMS), the Children's Sleep Habits Questionnaire (CSHQ), but did include other cognitive tests (Vineland Adaptive Behaviour Scales, Nonverbal IQ, Autism Diagnostic Observation Schedule). We identified significant associations between decreases in emotional, social and school domains of PedsQoL and the ADAMS subtests of Generalized Anxiety, Manic/Hy...
Source: Journal of Autism and Developmental Disorders - April 23, 2024 Category: Psychiatry Authors: Amrita Minhas Kerri Whitlock Cory Rosenfelt Julie Shatto Brittany Finlay Jennifer Zwicker Sarah Lippe Sebastien Jacquemont Randi Hagerman Kara Murias Francois V Bolduc Source Type: research
Adalimumab Dose Reduction and Withdrawal in Stable Non-Infectious Pediatric Uveitis: An Open-Label, Prospective, Pilot Study
CONCLUSIONS: In PNIU children who reached remission for 6 months, ADA dose reduction and withdrawal were associated with a high risk of inflammation recurrence. Timely adjustment of ADA to the last effective dosage frequency can regain control of the inflammation. Detection of ADA serum levels in patients with recurrence may help find the appropriate interval of ADA use.PMID:38652891 | DOI:10.1080/09273948.2024.2343084 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 23, 2024 Category: Allergy & Immunology Authors: P D Yuan Y W Hu X Q Chen G Y Chen Y Pan H Y Lao D Liang Source Type: research
The Use of the RETeval Portable Electroretinography Device for Low-Cost Screening: A Mini-Review
Klin Monbl Augenheilkd. 2024 Apr;241(4):533-537. doi: 10.1055/a-2237-3814. Epub 2024 Apr 23.ABSTRACTElectroretinography (ERG) provides crucial insights into retinal function and the integrity of the visual pathways. However, ERG assessments classically require a complicated technical background with costly equipment. In addition, the placement of corneal or conjunctival electrodes is not always tolerated by the patients, which restricts the measurement for pediatric evaluations. In this short review, we give an overview of the use of the RETeval portable ERG device (LKC Technologies, Inc., Gaithersburg, MD, USA), a modern ...
Source: Klinische Monatsblatter fur Augenheilkunde - April 23, 2024 Category: Opthalmology Authors: Amr Saad Ferhat Turgut Chiara Sommer Matthias Becker Delia DeBuc Mirella Barboni Gabor Mark Somfai Source Type: research
Positive Airway Pressure and Metabolic Markers in Children With Obstructive Sleep Apnea
CONCLUSIONS: Although evidence on effects of PAP on metabolic markers in children with OSA is encouraging, available literature is limited. Longitudinal studies are still required to further assess the long-term influence of PAP on metabolic and inflammatory markers, particularly in children with obesity.PMID:38653555 | DOI:10.4187/respcare.11679 (Source: Respiratory Care)
Source: Respiratory Care - April 23, 2024 Category: Respiratory Medicine Authors: Christopher A Gerdung Daniel B Ofosu Sara Rodriguez-Lopez Stefan Palkowski Diana Keto-Lambert Meng Lin Maria L Castro-Codesal Source Type: research
Pediatric and Young Adult Trauma Recidivism
CONCLUSIONS: Pediatric/young adult trauma recidivism is associated with specific characteristics including male, African American race, penetrating trauma, and uninsured status. Recidivists are primarily presenting from a zip code with low socioeconomic status. It is critical to develop targeted interventions to help this population in trauma prevention.PMID:38653577 | DOI:10.1177/00031348241248698 (Source: The American Surgeon)
Source: The American Surgeon - April 23, 2024 Category: Surgery Authors: Alison Lehane Elizabeth Wood Sarah Pranikoff Martin Avery Thomas Pranikoff Source Type: research
Prediction of High-Risk Neuroblastoma Among Neuroblastic Tumors Using Radiomics Features Derived from Magnetic Resonance Imaging: A Pilot Study
CONCLUSION: An MRI-based radiomics model can help predict high-risk neuroblastoma among neuroblastic tumors.PMID:38653568 | DOI:10.3349/ymj.2023.0192 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - April 23, 2024 Category: Universities & Medical Training Authors: Jisoo Kim Young Hun Choi Haesung Yoon Hyun Ji Lim Jung Woo Han Mi-Jung Lee Source Type: research
Metabolic dysfunction-associated steatotic liver disease: Evolution of the final terminology
Eur J Intern Med. 2024 Apr 22:S0953-6205(24)00173-0. doi: 10.1016/j.ejim.2024.04.013. Online ahead of print.ABSTRACTThe medical term nonalcoholic fatty liver disease (NAFLD) was coined in 1986 for a condition that has since become the most prevalent liver disorder worldwide. In the last 3 years, the global professional community launched 2 consecutive efforts to purge NAFLD from the medical dictionary and recommended new terms based on disease pathophysiology rather than distinction from similar conditions featuring liver steatosis. A consensus by renowned clinical scholars primarily residing in the Asian-Pacific region in...
Source: European Journal of Internal Medicine - April 23, 2024 Category: Internal Medicine Authors: Piero Portincasa Gyorgy Baffy Source Type: research
Diagnostic Evaluation of Autism Spectrum Disorder in Pediatric Primary Care
CONCLUSIONS: This model was successful in shortening the interval from referral to diagnosis resulting in significant decrease of age at diagnosis compared with the national average. Widespread implementation could improve access to timely diagnostic services and improve outcomes for children with ASD.PMID:38650542 | DOI:10.1177/21501319241247997 (Source: Primary Care)
Source: Primary Care - April 23, 2024 Category: Primary Care Authors: Arwa K Nasir Whitney Strong-Bak Marie Bernard Source Type: research
Early career investigator biocommentary: Lauren Erdman
Pediatr Res. 2024 Apr 23. doi: 10.1038/s41390-024-03216-1. Online ahead of print.NO ABSTRACTPMID:38654094 | DOI:10.1038/s41390-024-03216-1 (Source: Pediatric Research)
Source: Pediatric Research - April 23, 2024 Category: Pediatrics Authors: Lauren Erdman Source Type: research
Perforated Appendicitis in Children: Management, Microbiology, and Antibiotic Stewardship
Paediatr Drugs. 2024 Apr 24. doi: 10.1007/s40272-024-00630-0. Online ahead of print.ABSTRACTAlthough appendicitis has been described for more than 300 years, its optimal management remains a topic of active investigation. Acute appendicitis is the most common cause of peritonitis in children, and rates of perforated appendicitis are much higher in children than in adults. Increased risk for perforated appendicitis in children is related to a delay in diagnosis due to age, size, access to care, and more. Surgical options include immediate appendectomy versus nonoperative management with intravenous antibiotics ± a drainage...
Source: Paediatric Drugs - April 23, 2024 Category: Pediatrics Authors: Katherine B Snyder Catherine J Hunter Christie L Buonpane Source Type: research
