Drug Retention Rate and Factors Associated with Discontinuation of Interleukin-17 Inhibitors in Patients with Axial Spondyloarthritis
CONCLUSION: In patients with axSpA in whom TNFis failed, the long-term drug retention rate of IL-17is appears to be acceptable, with a 3-year drug retention rate of approximately 60%. Current smoking was associated with a higher risk of discontinuing IL-17is, whereas previous use of ≥3 TNFis was associated with a lower risk of discontinuing IL-17is.PMID:37992741 | PMC:PMC10681822 | DOI:10.3349/ymj.2023.0151 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Authors: Oh Chan Kwon Min-Chan Park Source Type: research

Nusinersen for Spinal Muscular Atrophy Type I with Chronic Respiratory Failure: A Retrospective Study in South Korea
CONCLUSION: Nusinersen is safe and effective in patients with SMA type I, even those with chronic respiratory failure and those on permanent ventilation. No significant adverse effects of nusinersen were observed.PMID:37992742 | PMC:PMC10681826 | DOI:10.3349/ymj.2023.0080 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Authors: Hui Jin Shin Ji-Hoon Na Hyunjoo Lee Young-Mock Lee Source Type: research

Clinical Features of Delirium among Patients in the Intensive Care Unit According to Motor Subtype Classification: A Retrospective Longitudinal Study
CONCLUSION: Managing and predicting delirium patients based on whether patients experienced non-hypoactive delirium may be clinically important. Variables obtained during the initial 48 hours can be used to determine which patients are likely to require invasive interventions.PMID:37992743 | PMC:PMC10681821 | DOI:10.3349/ymj.2023.0113 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Authors: Junhyung Kim Jooyoung Oh Ji Seon Ahn Kyungmi Chung Min-Kyeong Kim Cheung Soo Shin Jin Young Park Source Type: research

Combination of Fractional Microneedling Radiofrequency and Ablative Fractional Laser versus Ablative Fractional Laser Alone for Acne and Acne Scars
CONCLUSION: FMR combined with AFL is a well-tolerated and effective treatment modality for inflammatory acne and acne scarring.PMID:37992744 | PMC:PMC10681823 | DOI:10.3349/ymj.2023.0234 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Authors: Jemin Kim Sang Gyu Lee Sooyeon Choi Joohee Lee Young In Lee Jihee Kim Ju Hee Lee Source Type: research

A Comparative Study of a Sternum-Sparing Procedure and Clamshell Incision in Bilateral Lung Transplantation
CONCLUSION: Less-invasive lung transplantation via sternum-sparing BAT is a safe procedure with low morbidity and favorable outcomes. Preventing sternal instability enables more stable breathing after surgery, earlier weaning from mechanical ventilation, and faster recovery to routine activities.PMID:37992745 | PMC:PMC10681828 | DOI:10.3349/ymj.2023.0104 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Authors: Jong Myung Park Joohyung Son Do Hyung Kim Bong Soo Son Source Type: research

< sup > 18 < /sup > F-FDG PET/CT Parameters Enhance MRI Radiomics for Predicting Human Papilloma Virus Status in Oropharyngeal Squamous Cell Carcinoma
CONCLUSION: When combined with an MRI radiomics model, 18F-FDG PET/CT exhibits incremental value in predicting HPV status in patients with OPSCC.PMID:37992746 | PMC:PMC10681825 | DOI:10.3349/ymj.2023.0187 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Authors: Kwan Hyeong Jo Jinna Kim Hojin Cho Won Jun Kang Seung-Koo Lee Beomseok Sohn Source Type: research

The First Korean Adult Case of Progressive Familial Intrahepatic Cholestasis Type 7 with Novel < em > USP53 < /em > Splicing Variants by Next Generation Sequencing
Yonsei Med J. 2023 Dec;64(12):745-749. doi: 10.3349/ymj.2023.0161.ABSTRACTProgressive familial intrahepatic cholestasis (PFIC) is a group of rare genetic disorders caused by defects in biliary epithelial transporters. It mostly presents as low γ-glutamyltransferase cholestasis. Recently, USP53 has been identified as one of the novel genes associated with PFIC. Herein, we report a 21-year-old Korean male patient with a late-onset PFIC. Initial work-up, including whole genome sequencing, did not find any associated gene. However, reviewing sequencing data identified novel compound heterozygous variants in splicing site of U...
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Authors: Soomin Ahn Jonggi Choi Sook-Hyang Jeong Source Type: research

Erratum to "Bone Flap Changes after Cranioplasty Using Frozen Autologous Bone Flaps: A Three-Dimensional Volumetric Reconstruction Study" by Lee JH, et al. (Yonsei Med J 2019 Nov;60(11):1067-1073)
Yonsei Med J. 2023 Dec;64(12):750. doi: 10.3349/ymj.2019.0141.er.ABSTRACTThis corrects the article on p. 1067 in vol. 60, PMID: 31637889.PMID:37992748 | PMC:PMC10681824 | DOI:10.3349/ymj.2019.0141.er (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Source Type: research

Erratum to "National Trends in Hospitalization for Ambulatory Care Sensitive Conditions among Korean Adults between 2008 and 2019" by Park H, et al. (Yonsei Med J 2022 Oct;63(10):948-955)
Yonsei Med J. 2023 Dec;64(12):751. doi: 10.3349/ymj.2022.0110.er.ABSTRACTThis corrects the article on p. 948 in vol. 63, PMID: 36168248.PMID:37992749 | PMC:PMC10681820 | DOI:10.3349/ymj.2022.0110.er (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Source Type: research

Drug Retention Rate and Factors Associated with Discontinuation of Interleukin-17 Inhibitors in Patients with Axial Spondyloarthritis
CONCLUSION: In patients with axSpA in whom TNFis failed, the long-term drug retention rate of IL-17is appears to be acceptable, with a 3-year drug retention rate of approximately 60%. Current smoking was associated with a higher risk of discontinuing IL-17is, whereas previous use of ≥3 TNFis was associated with a lower risk of discontinuing IL-17is.PMID:37992741 | PMC:PMC10681822 | DOI:10.3349/ymj.2023.0151 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Authors: Oh Chan Kwon Min-Chan Park Source Type: research

Nusinersen for Spinal Muscular Atrophy Type I with Chronic Respiratory Failure: A Retrospective Study in South Korea
CONCLUSION: Nusinersen is safe and effective in patients with SMA type I, even those with chronic respiratory failure and those on permanent ventilation. No significant adverse effects of nusinersen were observed.PMID:37992742 | PMC:PMC10681826 | DOI:10.3349/ymj.2023.0080 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Authors: Hui Jin Shin Ji-Hoon Na Hyunjoo Lee Young-Mock Lee Source Type: research

Clinical Features of Delirium among Patients in the Intensive Care Unit According to Motor Subtype Classification: A Retrospective Longitudinal Study
CONCLUSION: Managing and predicting delirium patients based on whether patients experienced non-hypoactive delirium may be clinically important. Variables obtained during the initial 48 hours can be used to determine which patients are likely to require invasive interventions.PMID:37992743 | PMC:PMC10681821 | DOI:10.3349/ymj.2023.0113 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Authors: Junhyung Kim Jooyoung Oh Ji Seon Ahn Kyungmi Chung Min-Kyeong Kim Cheung Soo Shin Jin Young Park Source Type: research

Combination of Fractional Microneedling Radiofrequency and Ablative Fractional Laser versus Ablative Fractional Laser Alone for Acne and Acne Scars
CONCLUSION: FMR combined with AFL is a well-tolerated and effective treatment modality for inflammatory acne and acne scarring.PMID:37992744 | PMC:PMC10681823 | DOI:10.3349/ymj.2023.0234 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Authors: Jemin Kim Sang Gyu Lee Sooyeon Choi Joohee Lee Young In Lee Jihee Kim Ju Hee Lee Source Type: research

A Comparative Study of a Sternum-Sparing Procedure and Clamshell Incision in Bilateral Lung Transplantation
CONCLUSION: Less-invasive lung transplantation via sternum-sparing BAT is a safe procedure with low morbidity and favorable outcomes. Preventing sternal instability enables more stable breathing after surgery, earlier weaning from mechanical ventilation, and faster recovery to routine activities.PMID:37992745 | PMC:PMC10681828 | DOI:10.3349/ymj.2023.0104 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Authors: Jong Myung Park Joohyung Son Do Hyung Kim Bong Soo Son Source Type: research

< sup > 18 < /sup > F-FDG PET/CT Parameters Enhance MRI Radiomics for Predicting Human Papilloma Virus Status in Oropharyngeal Squamous Cell Carcinoma
CONCLUSION: When combined with an MRI radiomics model, 18F-FDG PET/CT exhibits incremental value in predicting HPV status in patients with OPSCC.PMID:37992746 | PMC:PMC10681825 | DOI:10.3349/ymj.2023.0187 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - November 22, 2023 Category: Universities & Medical Training Authors: Kwan Hyeong Jo Jinna Kim Hojin Cho Won Jun Kang Seung-Koo Lee Beomseok Sohn Source Type: research