The First Case of a Korean Patient with a Mutation-Confirmed Tumor Necrosis Factor Receptor-Associated Periodic Syndrome
Yonsei Med J. 2024 Apr;65(4):241-245. doi: 10.3349/ymj.2023.0366.ABSTRACTTumor necrosis factor receptor-associated periodic syndrome (TRAPS, OMIM: #142680) is a rare autoinflammatory disease (AID) with recurrent febrile episodes. To our knowledge, we report herein the first case of a patient with TRAPS in South Korea whose symptoms included fever, arthralgia, abdominal pain, rash, myalgia, cough, and lymphadenopathy. A pathogenic de novo mutation, c.175T>C (p.Cys59Arg), in the tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) gene, was confirmed by gene sequencing. The patient has been with tocilizumab (an...
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Seok-Jin Lee Jee Yeon Baek Ji Young Lee Ji-Man Kang Jong Gyun Ahn Source Type: research
Ssangcheon, Life of Lee Young-Choon (1903-1980)
Yonsei Med J. 2024 Apr;65(4):189-193. doi: 10.3349/ymj.2023.0445.NO ABSTRACTPMID:38515355 | DOI:10.3349/ymj.2023.0445 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Kang-Hyu Lee Joo-Min Lee Soon-Jae Yoon Chang-Seop Lee Source Type: research
Immune Cell-Mediated Autoimmune Responses in Severe Asthma
Yonsei Med J. 2024 Apr;65(4):194-201. doi: 10.3349/ymj.2023.0432.ABSTRACTSevere asthma (SA) has heterogeneous inflammatory phenotypes characterized by persistent airway inflammation (eosinophilic and/or neutrophilic inflammation) and remodeling. Various immune cells (eosinophils, neutrophils, and macrophages) become more activated and release inflammatory mediators and extracellular traps, damaging the protective barrier of airway epithelial cells and further activating other immune and structural cells. These cells play a role in autoimmune responses in asthmatic airways, where the adaptive immune system generates autoant...
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Thi Bich Tra Cao Quang Luu Quoc Jae-Hyuk Jang Hae-Sim Park Source Type: research
Evidence of Placental Villous Inflammation and Apoptosis in Third-Trimester Symptomatic SARS-CoV-2 Maternal Infection
CONCLUSION: The presence of SARS-CoV-2 spike protein as well as altered inflammatory and apoptotic processes may indicate the presence of placental disturbance in third-trimester maternal COVID-19 infection. The lack of correlation between placental disruption and maternal severity status suggests the need for more research to understand the infection process and any potential long-term impacts on all offsprings born to COVID-19-infected pregnant women.PMID:38515357 | DOI:10.3349/ymj.2023.0309 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Manggala Pasca Wardhana Kuntaman Kuntaman Budi Utomo Rozi Aditya Aryananda Salsabila Nabilah Rifdah Ifan Ali Wafa Almira Aulia Shahnaz Dahlia Ningrum Nareswari Imanadha Cininta Grace Ariani Jan Mm Van Lith Erry Gumilar Dachlan Source Type: research
Application of Data Mining Technology in the Screening for Gallbladder Stones: A Cross-Sectional Retrospective Study of Chinese Adults
CONCLUSION: The results of this study showed that MLP and J48 algorithms are effective at screening individuals for the risk of GS. The key attributes of data mining can further promote the prevention of GS through targeted community intervention, improve the outcome of GS, and reduce the burden on the medical system.PMID:38515358 | DOI:10.3349/ymj.2023.0246 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Shuang Wang Chenhui Bao Dongmei Pei Source Type: research
Effect of Dietary Habits on Alzheimer's Disease Progression
CONCLUSION: Eating a balanced diet and reducing salt intake were associated with a slower decline in dementia severity, cognition, and behavioral alterations in patients with ADD.PMID:38515359 | DOI:10.3349/ymj.2023.0119 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: So Hyun Ahn Jee Hyang Jeong Kyung Won Park Eun-Joo Kim Soo Jin Yoon Bora Yoon Jae-Won Jang Yangki Minn Seong Hye Choi Source Type: research
Physical Activity-Induced Modification of the Association of Long-Term Air Pollution Exposure with the Risk of Depression in Older Adults
CONCLUSION: We suggest that older adults who vigorously exercise outdoors may be susceptible to air pollution-related depression.PMID:38515360 | DOI:10.3349/ymj.2023.0292 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Woongbi Park Heeseon Jang Juyeon Ko Jungwoo Sohn Young Noh Sun-Young Kim Sang-Baek Koh Changsoo Kim Jaelim Cho Source Type: research
Trend in the Incidence of Severe Partial Edentulism among Adults Using the Korean National Health Insurance Service Claim Data, 2014-2018
CONCLUSION: The study showed that the incidence trend of SPE increased and decreased from 2014 to 2018. This result would be able to aid in the planning of public oral health, and may also serve as fundamental data for verifying the impact of the public oral health policies implemented.PMID:38515361 | DOI:10.3349/ymj.2023.0380 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Hyeonjeong Go Hoi-In Jung Song Vogue Ahn Jeonghoon Ahn Hosung Shin Atsuo Amano Youn-Hee Choi Source Type: research
The First Case of a Korean Patient with a Mutation-Confirmed Tumor Necrosis Factor Receptor-Associated Periodic Syndrome
Yonsei Med J. 2024 Apr;65(4):241-245. doi: 10.3349/ymj.2023.0366.ABSTRACTTumor necrosis factor receptor-associated periodic syndrome (TRAPS, OMIM: #142680) is a rare autoinflammatory disease (AID) with recurrent febrile episodes. To our knowledge, we report herein the first case of a patient with TRAPS in South Korea whose symptoms included fever, arthralgia, abdominal pain, rash, myalgia, cough, and lymphadenopathy. A pathogenic de novo mutation, c.175T>C (p.Cys59Arg), in the tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) gene, was confirmed by gene sequencing. The patient has been with tocilizumab (an...
Source: Yonsei Medical Journal - March 22, 2024 Category: Universities & Medical Training Authors: Seok-Jin Lee Jee Yeon Baek Ji Young Lee Ji-Man Kang Jong Gyun Ahn Source Type: research
Feasibility of Intraoperative Radiotherapy Tumor Bed Boost in Patients with Breast Cancer after Neoadjuvant Chemotherapy
CONCLUSION: Most patients successfully received IORT as a tumor bed boost after neoadjuvant chemotherapy. Thus, IORT may be a safe and feasible option for patients with advanced-stage breast cancer receiving neoadjuvant chemotherapy.PMID:38373832 | PMC:PMC10896667 | DOI:10.3349/ymj.2023.0229 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - February 19, 2024 Category: Universities & Medical Training Authors: Gowoon Yang Jun Won Kim Ik Jae Lee Joon Jeong Sung Gwe Ahn Soong June Bae Jee Hung Kim Yeona Cho Source Type: research
The Prediction Model of Non-Suicidal Self-Injury in Psychiatric Patients Using Decision Tree Analysis
CONCLUSION: The major contribution of this study is finding a combination of factors to predict the high-risk group of NSSI among psychiatric patients in Korea. This study provides evidence on the effect of rumination, working memory, and problematic alcohol use on NSSI. It is suggested that clinicians and researchers should pay more attention to emotion regulation and related vulnerabilities in preventing and treating NSSI.PMID:38373833 | PMC:PMC10896672 | DOI:10.3349/ymj.2023.0129 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - February 19, 2024 Category: Universities & Medical Training Authors: Kawon Kim Sungbum Woo Seok Hyeon Kim Sungwon Roh Sojung Kim Source Type: research
The Revo-i Robotic Surgical System in Advanced Pancreatic Surgery: A Second Non-Randomized Clinical Trial and Comparative Analysis to the da Vinci ™ System
CONCLUSION: In this single-arm prospective study with short-term follow-up at a single institution, the Revo-i robotic surgical system was safe and effective for advanced pancreatic surgery. Revo-i RPD is comparable to the da Vinci™ RPD and is expected to have wide clinical application.PMID:38373834 | PMC:PMC10896669 | DOI:10.3349/ymj.2023.0140 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - February 19, 2024 Category: Universities & Medical Training Authors: Ji Su Kim Munseok Choi Hyeo Seong Hwang Woo Jung Lee Chang Moo Kang Source Type: research
The Association between Serum Lipid Levels and Tinnitus Prevalence and Severity in Korean Elderly: A Nationwide Population-Based Cross-Sectional Study
CONCLUSION: This study revealed that hypertriglyceridemia and high TC/HDL-C ratio were significantly associated with an increased OR of tinnitus in Korean older adults.PMID:38373835 | PMC:PMC10896670 | DOI:10.3349/ymj.2022.0626 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - February 19, 2024 Category: Universities & Medical Training Authors: Hye Jun Lee Duk Chul Lee Choon Ok Kim Source Type: research
Computed Tomography Radiomics for Preoperative Prediction of Spread Through Air Spaces in the Early Stage of Surgically Resected Lung Adenocarcinomas
CONCLUSION: A quantitative CT radiomics model can assist in the non-invasive prediction of the presence of STAS in the early stage of lung adenocarcinomas.PMID:38373836 | PMC:PMC10896671 | DOI:10.3349/ymj.2023.0368 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - February 19, 2024 Category: Universities & Medical Training Authors: Young Joo Suh Kyunghwa Han Yonghan Kwon Hwiyoung Kim Suji Lee Sung Ho Hwang Myung Hyun Kim Hyun Joo Shin Chang Young Lee Hyo Sup Shim Source Type: research
Smartphone AI vs. Medical Experts: A Comparative Study in Prehospital STEMI Diagnosis
CONCLUSION: The digital STEMI biomarker, derived from printed prehospital ECGs, demonstrated non-inferiority to expert consensus, indicating a promising approach for enhancing prehospital telecardiology.PMID:38373837 | PMC:PMC10896668 | DOI:10.3349/ymj.2023.0341 (Source: Yonsei Medical Journal)
Source: Yonsei Medical Journal - February 19, 2024 Category: Universities & Medical Training Authors: Seung Hyo Lee Won Pyo Hong Joonghee Kim Youngjin Cho Eunkyoung Lee Source Type: research
