COVID19: ethnic, cardiovascular and renal: pandemic causing pandemonium.
PMID: 32762509 [PubMed - in process] (Source: Perfusion)
Source: Perfusion - August 13, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Punjabi PP Tags: Perfusion Source Type: research

Alternative technique of long acting cardioplegia delivery results in less hemodilution.
CONCLUSION: Besides the safe delivery of del-Nido cardioplegia, the National University Hospital Technique reduces hemodilution and provides other technical benefits including a steeper temperature gradient, modification of circuit configuration to deliver another cardioplegia while on bypass, as well as re-configuration of clamps to spike the base solution. PMID: 32777980 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - August 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Ong GS, Guim GS, Lim QX, Chay-Nancy HS, Jaafar NB, Lim CA, Clement CKH, Sazzad F, Kofidis T Tags: Perfusion Source Type: research

Individualized positive end-expiratory pressure setting in patients with severe acute respiratory distress syndrome supported with veno-venous extracorporeal membrane oxygenation.
This study aimed to determine the preferred method for setting positive end-expiratory pressure in patients with severe acute respiratory distress syndrome on veno-venous extracorporeal membrane oxygenation support. METHODS: We retrospectively reviewed all subjects supported with veno-venous extracorporeal membrane oxygenation for severe acute respiratory distress syndrome from 2009 to 2019 in the intensive care units in Tianjin Third Central Hospital. Subjects were divided into two groups according to the positive end-expiratory pressure titration method used: P-V curve (quasi-static pressure-volume curve-guided posi...
Source: Perfusion - August 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Yin C, Gao X, Cao C, Xu L, Lu X Tags: Perfusion Source Type: research

Regional oxygen saturation change rate for detection of leg ischemia in minimally invasive cardiac surgery.
Abstract INTRODUCTION: The criteria for placement of distal perfusion cannulas vary among reports. This cohort study aimed to establish a reproducible method to monitor critical leg ischemia during minimally invasive cardiac surgery. METHODS: We included 121 patients who underwent minimally invasive cardiac surgery via right thoracotomy with right femoral arterial cannulation from 2015 to 2018. The change rate of regional oxygen saturation (ΔrSO2) was calculated as follows: rSO2 (baseline) - rSO2 (actual number)/rSO2 (baseline). Patients were divided into Group N (ΔrSO2 &thins...
Source: Perfusion - August 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Shikata F, Nakamura Y, Okuzono Y, Uchigasaki Y, Yamauchi N Tags: Perfusion Source Type: research

Extracorporeal cardiopulmonary resuscitation with low pump flow for blocked modified Blalock-Taussig shunt followed by spontaneous recanalization.
Abstract A 2-week-old male newborn with a double inlet left ventricle developed a cardiac arrest following modified Blalock-Taussig anastomosis in pediatric intensive care unit. Probable causes of the arrest were hemodynamic instability and thrombosed shunt, which was later recanalized on extracorporeal membrane oxygenation therapy, which was successfully used with a pump flow lower than recommended in these patients-without the shunt clip, but without any complications. PMID: 32762308 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - August 6, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Bakos M, Dilber D, Belina D, Rubic F, Matic T Tags: Perfusion Source Type: research

Right watershed cerebral infarction following neck cannulation for veno-arterial extracorporeal membrane oxygenation in pediatric septic shock: a case series.
We describe here two infants requiring veno-arterial extracorporeal membrane oxygenation for septic shock who encountered right watershed infarction ipsilateral to carotid artery cannulation. Hemodynamic failure seems to be the most probable underlying mechanism. The asymmetry of transcranial Doppler metrics in one case and the low right regional cerebral oxygen saturation value observed soon after right cannulation in both cases suggest an insufficient cerebral collateral flow compensation. The risk of ipsilateral watershed injury should be considered before cervical cannulation, notably in the context of sepsis and an ev...
Source: Perfusion - August 5, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Chenouard A, Toulgoat F, Rolland A, Liet JM, Maminirina P, Joram N, Bourgoin P Tags: Perfusion Source Type: research

Acute isotonic hyponatremia after single dose histidine-tryptophan-ketoglutarate cardioplegia: an observational study.
Abstract INTRODUCTION: Histidine-tryptophan-ketoglutarate cardioplegia is used for prolonged myocardial protection in complex cardiac surgery. Administration leads to acute hyponatremia in a majority of patients, because of its low sodium concentration (15 mmol/L). However, histidine-tryptophan-ketoglutarate solution's osmolality is slightly hypertonic (310 mOsm/kg). Hypothesized was that acute isotonic hyponatremia will be induced, which does not need to be corrected with hypertonic saline. METHODS: Cardiac surgery patients who received histidine-tryptophan-ketoglutarate cardioplegia were inclu...
Source: Perfusion - August 5, 2020 Category: Cardiovascular & Thoracic Surgery Authors: van Houte J, Bindels AJ, Houterman S, Dong PV, den Ouden M, de Bock NE, Verberkmoes NJ, Curvers J, Bouwman AR Tags: Perfusion Source Type: research

Normoxic management of cardiopulmonary bypass reduces myocardial oxidative stress in adult patients undergoing coronary artery bypass graft surgery.
CONCLUSIONS: Normoxic cardiopulmonary bypass is associated with reduced myocardial oxidative stress compared to hyperoxic cardiopulmonary bypass in adult coronary artery bypass patients. PMID: 32755372 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - August 5, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Topcu AC, Bolukcu A, Ozeren K, Kavasoglu T, Kayacioglu I Tags: Perfusion Source Type: research

Evidence-based translational research approach may help to select the best femoral arterial cannula for adolescent/adult extracorporeal life support population.
r A PMID: 32757715 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - August 5, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Ündar A Tags: Perfusion Source Type: research

Myocardial protection in cardiac surgery: how limited are the options? A comprehensive literature review.
Abstract For patients undergoing cardiopulmonary bypass, myocardial protection is a key for successful recovery and improved outcomes following cardiac surgery that requires cardiac arrest. Different solutions, components and modes of delivery have evolved over the last few decades to optimise myocardial protection. These include cold and warm and blood and crystalloid solution through antegrade, retrograde or combined cardioplegia delivery approach. However, each method has its own advantages and disadvantages, posing a challenge to establish a gold-standard cardioplegic solution with an optimised mode of deliver...
Source: Perfusion - July 31, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Whittaker A, Aboughdir M, Mahbub S, Ahmed A, Harky A Tags: Perfusion Source Type: research

Corrigendum to 'New Noninvasive Methodology to Measure Cardiac Output in Veno-Venous Extracorporeal Membrane Oxygenation Patients'.
Authors: PMID: 32729354 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 30, 2020 Category: Cardiovascular & Thoracic Surgery Tags: Perfusion Source Type: research

The evolving role of the modern perfusionist: insights from transesophageal echocardiography.
Abstract Transesophageal echocardiography is a relatively non-invasive, mobile, safe imaging technique that is ideal for providing real-time information on cardiac anatomy and function during heart surgery. The technology has evolved from two-dimensional to real-time three-dimensional imaging during cardiac procedures, which has significantly benefited preoperative planning, intraoperative guidance, evaluation, and postoperative follow-up. Transesophageal echocardiography may serve the clinical perfusionist by providing imaging guidance for identifying potential problems before cardiopulmonary bypass, guiding the ...
Source: Perfusion - July 30, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Bouchez S, De Somer F Tags: Perfusion Source Type: research

Computed tomography angiography as an adjunct to computational fluid dynamics for prediction of oxygenator thrombus formation.
CONCLUSION: In the studied oxygenator, clot burden follows a pattern consistent with clinical observations. Computed tomography angiography-based flow analysis provides a useful adjunct to computational fluid dynamics-based flow analysis in understanding oxygenator thrombus formation. PMID: 32723149 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 29, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Conway RG, Zhang J, Jeudy J, Evans C, Li T, Wu ZJ, Griffith BP Tags: Perfusion Source Type: research

Myocardial perfusion imaging and appropriateness of the test for preoperative cardiac risk evaluation in an Iranian population: clinical role of Duke Activity Status Index.
CONCLUSION: Either Duke Activity Status Index is not a proper tool for calculation of metabolic equivalents or the appropriate use criteria is not operational in the population of Iranian preoperative patients in which cultural factors may contribute. PMID: 32723151 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 29, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Salehi Y, Farzanehfar S, Naseri M, Sherafati A, Ranjbar S, Abbasi M Tags: Perfusion Source Type: research

Generalized convulsive status epilepticus after retrograde type A aortic dissection surgery.
CONCLUSION: Generalized convulsive status epilepticus should be alert for avoiding delay in the rehabilitation particularly after aortic dissection surgery. Under the good condition of ventilation, combining morphine with midazolam or diazepam can more effectively relieve the symptoms. PMID: 32723152 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 29, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Li Y, Wu Q, Shi H, Chen D, Zhang C Tags: Perfusion Source Type: research

Simulation-based training of critical events during cardiopulmonary bypass: importance of a critical events checklist.
CONCLUSION: Evaluation of critical events during simulated cardiopulmonary bypass shows that the scenario is realistic and relevant for clinical practice. Integrating a critical events checklist improves the probability of correct decision-making and shortens the correct decision time. Temporal workload is increased when using a checklist. Eye tracking and heart rate variability are well suited to evaluate participants' behaviors and stress levels. All participants welcomed simulation training for critical incidents. PMID: 32713287 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 25, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Merkle F, Kurtovic D, Matschke A, Haupt B, Falk V, Starck C Tags: Perfusion Source Type: research

The role of strut chordae in mitral valve competence during annular dilation.
Abstract Strut chordae, on their own, are not typically thought to aid mitral valve competence. The aim of this study is to assess whether strut chordae aid mitral valve competence during acute annular dilation. Twelve porcine hearts were dissected and tested using an in vitro simulator, with the mitral annulus tested in either a 'normal' or a dilated configuration. The normal configuration included a diameter of 30 mm, a posterior leaflet 'radius' of 15 mm and a commissural corner 'radius' of 7.5 mm; the dilated annular template instead used dimensions of 50 mm, 25 mm and 12.5&t...
Source: Perfusion - July 22, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Taylor S, Buchan KG, Espino DM Tags: Perfusion Source Type: research

Use of del Nido cardioplegia in acute aortic dissection surgery.
Abstract OBJECTIVE: Del Nido cardioplegia solution provides a depolarized hyperkalemic arrest lasting up to 60 minutes. Single-dose del Nido cardioplegia solution may offer an alternative myocardial protection strategy to conventional whole blood cardioplegia following acute aortic dissection surgery. METHODS: We retrospectively reviewed 122 consecutive patients with acute aortic dissection undergoing arch reconstruction surgery procedure with cardioplegia arrest from January 2017 to December 2019. Patients exclusively received with whole blood cardioplegia (n = 60, January 2017-December ...
Source: Perfusion - July 22, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Chen H, Wang L, Wan L, Xiao L, Chen X Tags: Perfusion Source Type: research

Severe aortic valve regurgitation requiring mechanical aortic valve replacement following Impella device implantation.
CONCLUSION: Echocardiography must include frequent assessment of both valvular and myocardial function after Impella removal. PMID: 32664788 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 15, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Vila P, de Vere F, Simon A, Walker C Tags: Perfusion Source Type: research

Perioperative management of COVID-19 patients undergoing cardiac surgery with cardiopulmonary bypass.
Abstract Coronavirus disease 2019 (COVID-19) is a serious health concern which affects all healthcare professionals worldwide. The pandemic puts health services, including cardiac surgery units, under escalating pressure. There are significant challenges caused by this novel virus and ensuing disease that leads to great uncertainty. While it has been advocated to delay elective surgeries, most cardiac surgical patients present in a more urgent manner which elevates the critical nature for intervention, which may make the surgical decision inevitable. To date, no definitive treatments to the pandemic have been prom...
Source: Perfusion - July 15, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Gunaydin S, Stammers AH Tags: Perfusion Source Type: research

Comparison of CHA2DS2-VASc and C2HEST scores for predicting the incidence of atrial fibrillation among patients with end-stage renal disease.
CONCLUSION: Both scores yield almost identical AUROC values implying no difference in predictive power. Further work is warranted to verify the prognostic value of the current scores. PMID: 32666900 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 15, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Hu WS, Lin CL Tags: Perfusion Source Type: research

Predictiveness of different preoperative risk assessments for postoperative bleeding after coronary artery bypass grafting surgery.
CONCLUSION: Predicting postoperative bleeding and transfusion rates with preoperative risk scores in patients undergoing coronary artery bypass graft surgery will provide valuable information to physicians for establishing a proper patient blood management protocol and this will decrease excessive transfusions, unnecessary reoperations as well as improve postoperative outcomes. PMID: 32659163 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Gunertem E, Urcun S, Pala AA, Budak AB, Ercisli MA, Gunaydin S Tags: Perfusion Source Type: research

Echocardiographic findings on aortic stenosis: an observational, prospective, and multi-center registry.
CONCLUSION: Left atrial dilatation is one of the first changes to take place in low-flow low-gradient aortic stenosis patients even when left ventricular dimensions and function remains intact. Global longitudinal strain is an important determinant of left ventricular systolic and diastolic dysfunction and right ventricular function is an important parameter of aortic stenosis assessment. Accordingly, our registry has further shed the light on these indices role as multisite follow-up of aortic stenosis. PMID: 32650695 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Anwer S, Oğuz D, Galian-Gay L, Peovska Mitevska I, Baghdassarian L, Dulgheru R, Lapinskas T, Santoro C, Loizos S, Cameli M, Srbinovska E, Grapsa J, Magne J, Donal E Tags: Perfusion Source Type: research

Prolonged duration of repolarization and decreased conduction velocity in the atrial myocardium after hypothermic ischemia-reperfusion may be related to expressions of inward rectifier potassium channel 2.1 protein and connexin 40.
Abstract OBJECTIVES: The study aimed to determine the role of inward rectifier potassium channel 2.1 protein and connexin 40 expressions in regulating the duration of repolarization and conduction velocity of right atrial myocardium in rats following hypothermic ischemia-reperfusion. METHODS: The Langendorff isolated rat cardiac perfusion models were divided into control (C) and hypothermic ischemia-reperfusion groups, with 8 models in group C and 16 models in group ischemia-reperfusion. Depending on the incidence of atrial arrhythmia after reperfusion, the models in group ischemia-reperfusion were further di...
Source: Perfusion - July 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: He Y, Wang G, Gao H, Liu Y, Li H, Feng Y, Tang J Tags: Perfusion Source Type: research

Antithrombin use during pediatric cardiac extracorporeal membrane oxygenation admission: insights from a national database.
CONCLUSION: Antithrombin administration is associated with increased mortality, a shorter length of stay, and decreased billing cost. Recently, antithrombin usage has been decreasing-potentially due to the reported lack of clinical benefit. Together, these results reinforce that antithrombin may not be indicated for all pediatric extracorporeal membrane oxygenation patients. PMID: 32650697 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Aiello SR, Flores S, Coughlin M, Villarreal EG, Loomba RS Tags: Perfusion Source Type: research

Case report of successful peripheral veno-arterial extracorporeal membrane oxygenation in a patient with chronic type B aortic dissection.
Abstract A case report of successful application of peripheral veno-arterial extracorporeal membrane oxygenation in a patient with chronic type B aortic dissection and myocardial stunning to bridge to recovery was presented. Good outcomes from the application of peripheral veno-arterial extracorporeal membrane oxygenation in aortic dissection have rarely been reported, and the considerations of starting veno-arterial extracorporeal membrane oxygenation in this situation were seldom discussed. The orthodox that peripheral veno-arterial extracorporeal membrane oxygenation is an absolute contraindication for initiati...
Source: Perfusion - July 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Au SY, Fong KM, Ng WG, So SO, Leung KA Tags: Perfusion Source Type: research

Bilateral sequential lung transplantation in Jehovah's Witnesses.
We report two successful cases of bilateral sequential lung transplantation in Jehovah's Witness patients with excellent long-term follow-up. PMID: 32650703 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Chan EG, Morrell MR, Chan PG, Sanchez PG Tags: Perfusion Source Type: research

A case of vaping-induced acute respiratory distress syndrome requiring extracorporeal life support.
CONCLUSION: Extracorporeal life support can be successfully utilized as a bridge to recovery in vaping-induced severe acute respiratory distress syndrome. PMID: 32650708 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Krishnan S, Thind GS, Soliman M, Tolle L, Mireles-Cabodevila E, Adi A, Anandamurthy B, Bribriesco A, Yun J Tags: Perfusion Source Type: research

Delayed graft function and perfusion parameters of kidneys from uncontrolled donors after circulatory death.
Abstract Better preservation and evaluation of kidneys from donors after circulatory death serve to increase the number of kidneys available for transplantation and hypothermic machine perfusion has been shown to decrease ischemia reperfusion injury and delayed graft function. Data on relation between hemodynamic parameters during hypothermic machine perfusion and delayed graft function in kidneys from donors after circulatory death are so far scarce and not univocal. We aimed at assessing whether hemodynamic parameters measured during hypothermic machine perfusion (flow, mean perfusion pressure, and renal resista...
Source: Perfusion - July 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Peris A, Fulceri GE, Lazzeri C, Bonizzoli M, Li Marzi V, Serni S, Cirami L, Migliaccio ML Tags: Perfusion Source Type: research

Veno-venous extracorporeal membrane oxygenation for COVID-19-associated pediatric acute respiratory distress syndrome.
CONCLUSION: We report the use of veno-venous extracorporeal membrane oxygenation as a bridge to lung recovery in a pediatric patient with severe pediatric acute respiratory distress syndrome due to COVID-19. PMID: 32643551 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 9, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Lewis D, Fisler G, Schneider J, Sweberg T, Murphy K, Sathya C, Silver P, Taylor MD Tags: Perfusion Source Type: research

Sterility and performance of open and closed extracorporeal circuits after long-term dry-wet setups.
This study was undertaken to determine a safe deviation from standardized recommendations. METHODS: Open (cardiopulmonary bypass) circuits and closed extracorporeal membrane oxygenation circuits were setup dry for up to 60 days and wet primed for up to 6 weeks with one control inoculated with Escherichia coli. Open circuits were cultured daily, closed circuits weekly. Circuits were primed with blood, albumin, heparin, NaHCO3, and CaCl2. Baseline pCO2, pO2, hemoglobin, lactate dehydrogenase, and plasma free hemoglobin were measured. Circuits were recirculated at a blood flow of 6 Liters/minute with...
Source: Perfusion - July 8, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Deptula J, McGrath C, Preston T, Miller H, Yen B, Munari L, Setty SP Tags: Perfusion Source Type: research

Pressure and flow properties of dual-lumen cannulae for extracorporeal membrane oxygenation.
r A PMID: 32627656 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 6, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Ündar A Tags: Perfusion Source Type: research

Oxygenator impact on voriconazole in extracorporeal membrane oxygenation circuits.
CONCLUSION: This ex vivo investigation demonstrated substantial voriconazole loss within an extracorporeal membrane oxygenation circuit with an oxygenator in series with both sizes of the Quadrox-i oxygenator at 24 hours and no significant voriconazole loss in the absence of an oxygenator. Further evaluations with multiple dose in vitro and in vivo investigations are needed before specific voriconazole dosing recommendations can be made for clinical application with extracorporeal membrane oxygenation. PMID: 32627659 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 6, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Cies JJ, Moore WS, Giliam N, Low T, Marino D, Deacon J, Enache A, Chopra A Tags: Perfusion Source Type: research

Risk factors for agitation and hyperactive delirium in adult postcardiotomy patients with extracorporeal membrane oxygenation support: an observational study.
CONCLUSION: Our results suggest that the prevalence of agitation and hyperactive delirium in postcardiotomy patients with extracorporeal membrane oxygenation support is high. In addition, previous stroke and severe mean arterial pressure reduction before extracorporeal membrane oxygenation initiation is predictive of agitation and hyperactive delirium. PMID: 32627668 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 4, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Wang H, Hou D, Tian X, Wang L, Li C, Jia M, Hou X Tags: Perfusion Source Type: research

Is there a "safe" suction pressure in the venous line of extracorporeal circulation system?
Is there a "safe" suction pressure in the venous line of extracorporeal circulation system? Perfusion. 2020 Jul 04;:267659120936453 Authors: Ganushchak YM, Körver EP, Maessen JG Abstract Successes of extracorporeal life support increased the use of centrifugal pumps. However, reports of hemolysis call for caution in using these pumps, especially in neonatology and in pediatric intensive care. Cavitation can be a cause of blood damage. The aim of our study was to obtain information about the cavitation conditions and to provide the safest operating range of centrifugal pumps. A series of...
Source: Perfusion - July 4, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Ganushchak YM, Körver EP, Maessen JG Tags: Perfusion Source Type: research

Modified cardiopulmonary bypass circuit for the use of the AngioVac ® system in a case with high paradoxical embolization risk.
We describe a modified cardiopulmonary bypass circuit for the use of the AngioVac® system that enables full cardiopulmonary support and reduces paradoxical thromboembolic risk. PMID: 32613901 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - July 2, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Schmiady MO, Kucher N, Nagaraj N, Schürner AM, Maisano F, Ouda A Tags: Perfusion Source Type: research

Predicting short-term outcomes in patients supported with venoarterial extracorporeal membrane oxygenation.
PMID: 32558633 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - June 21, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Hou X Tags: Perfusion Source Type: research

Application of goal-directed therapy for the use of concentrated antithrombin for heparin resistance during cardiac surgery.
Abstract The maintenance of anticoagulation in adult patients undergoing cardiopulmonary bypass is dependent upon a number of factors, including heparin concentration and adequate antithrombin activity. Inadequate anticoagulation increases the risk of thrombosis and jeopardizes both vascular and extracorporeal circuit integrity. The purpose of this study was to evaluate a goal-directed approach for the use of antithrombin in patients who were resistant to heparin. Following institutional review board approval, data were obtained from quality improvement records. A goal-directed protocol for antithrombin was establ...
Source: Perfusion - June 13, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Stammers AH, Francis SG, Miller R, Nostro A, Tesdahl EA, Mongero LB Tags: Perfusion Source Type: research

Survival following venoarterial extracorporeal membrane oxygenation in postcardiotomy cardiogenic shock adults.
The objective of this study was to examine the survival outcomes and identify mortality risk factors for coronary artery bypass grafting patients who received venoarterial extracorporeal membrane oxygenation for postcardiotomy cardiogenic shock. METHODS: Data from 121 consecutive venoarterial extracorporeal membrane oxygenation-treated coronary artery bypass grafting patients at the Beijing Anzhen Hospital between January 2012 and December 2016 were analyzed. Multivariable Cox regression modeling was used to identify factors independently associated with 36-month mortality. RESULTS: Seventy-seven patients (64%) c...
Source: Perfusion - June 12, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Chen F, Wang L, Shao J, Wang H, Hou X, Jia M Tags: Perfusion Source Type: research

Surgical treatment of coronary atherosclerotic heart disease with right coronary artery aneurysm: a case report.
CONCLUSION: The standard surgical treatment for coronary artery aneurysms is unclear. For symptomatic large coronary aneurysms, ligation of coronary artery aneurysms with additional coronary artery bypass grafting can achieve good results. PMID: 32529911 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - June 12, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Wang F, Liu G, Mao X Tags: Perfusion Source Type: research

Life-threatening antineutrophil cytoplasmic antibody-associated vasculitis after influenza A H1N1 infection requiring veno-venous extracorporeal membrane oxygenation.
We present a case of severe antineutrophil cytoplasmic autoantibody-associated pulmonary vasculitis, managed with veno-venous extracorporeal membrane oxygenation at the initial phase. Despite the significant challenges raised with the use of extracorporeal membrane oxygenation in pulmonary hemorrhage cases, extracorporeal membrane oxygenation may have a significant impact on outcome in this setting, by providing adequate time for a successful immunosuppressive treatment. PMID: 32529913 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - June 12, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Frantzeskaki FG, Dimopoulos S, Konstantonis D, Katsibri P, Kostopanagiotou K, Theodorakopoulou M, Diakaki C, Dougenis D, Boumpas D, Karabinis A, Armaganidis A, Tsangaris I Tags: Perfusion Source Type: research

Minimally invasive extracorporeal circulation is a cost-effective alternative to conventional extracorporeal circulation for coronary artery bypass grafting: propensity matched analysis.
Abstract INTRODUCTION: Minimally invasive extracorporeal circulation has developed with the aim of reducing the impact of the adverse effects associated with conventional extracorporeal circulation. The aim of this study was to compare outcomes for patients undergoing coronary artery bypass grafting using minimally invasive extracorporeal circulation with those performed using conventional extracorporeal circulation. METHODS: A retrospective analysis was performed of patients undergoing minimally invasive extracorporeal circulation coronary artery bypass grafting at a single centre. 2:1 propensity matching wa...
Source: Perfusion - June 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Ali JM, Kovzel M, McPhilimey E, Colah S, De Silva R, Moorjani N Tags: Perfusion Source Type: research

Anticoagulation management during pulmonary endarterectomy with cardiopulmonary bypass and deep hypothermic circulatory arrest.
Abstract INTRODUCTION: Pulmonary endarterectomy requires cardiopulmonary bypass and deep hypothermic circulatory arrest, which may prolong the activated clotting time. We investigated whether activated clotting time-guided anticoagulation under these circumstances suppresses hemostatic activation. METHODS: Individual heparin sensitivity was determined by the heparin dose-response test, and anticoagulation was monitored by the activated clotting time and heparin concentration. Perioperative hemostasis was evaluated by thromboelastometry, platelet aggregation, and several plasma coagulation markers. RESULT...
Source: Perfusion - June 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Veerhoek D, van Barneveld LJ, Haumann RG, Kamminga SK, Vonk AB, Boer C, Symersky P Tags: Perfusion Source Type: research

Loading doses of ticagrelor versus clopidogrel in preventing periprocedural myocardial infarction in Asian patients with acute coronary syndrome.
CONCLUSION: Pretreatment with a loading dose of ticagrelor seems to be superior in reducing the incidence of percutaneous coronary intervention-related periprocedural myocardial infarction in Asian patients with acute coronary syndrome as compared with clopidogrel. PMID: 32522095 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - June 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Zhang YR, Xue ZK, Chen KY, Xu LX, Wang WD, Tao HY, Liu T, Che JJ, Wang XW, Rha SW, Wang JR, Wang P Tags: Perfusion Source Type: research

Clinical outcomes associated with retrograde arterial perfusion in minimally invasive mitral valve surgery: a systematic review.
CONCLUSION: Retrograde arterial perfusion in minimally invasive mitral valve surgery may be associated with an increased risk of neurologic events, without affecting the risk of 30-day mortality or renal failure. Although these patterns were identified, an overall paucity of evidence justifies further study. PMID: 32519587 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - June 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Burns DJ, Birla R, Vohra HA Tags: Perfusion Source Type: research

Feasibility study of a novel method of concentrating fresh frozen plasma by hemoconcentrating filter outside cardiopulmonary bypass.
PMID: 32519614 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - June 10, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Sajima T, Momose N, Ishiguro Y Tags: Perfusion Source Type: research

Acute kidney injury, stroke and death after cardiopulmonary bypass surgery: the role of perfusion flow and pressure.
This study aims to evaluate the role of low perfusion flow and pressure in the development of cardiopulmonary bypass-associated acute kidney injury, stroke and death, using multicentre registry data. METHODS: We identified patients from the Australian and New Zealand Collaborative Perfusion Registry who underwent coronary artery bypass grafting and/or valvular surgery between 2008 and 2018. Primary predictor variables were the length of time the perfusion flow was
Source: Perfusion - June 9, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Turner L, Hardikar A, Jose MD, Bhattarai K, Fenton C, Sharma R, Kirkland G, Jeffs L, Breslin M, Silva Ragaini B, Newland RF Tags: Perfusion Source Type: research

Pressure and flow properties of dual-lumen cannulae for extracorporeal membrane oxygenation.
CONCLUSION: Non-standardized testing of pressure-flow properties of extracorporeal membrane oxygenation dual-lumen cannulae prevents an adequate prediction of pressure-flow results when these cannulae are used in patients. Properties of dual-lumen cannulae may vary between sizes within same cannula family, in particular concerning the drainage flow. PMID: 32500818 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - June 5, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Broman LM, Westlund CJ, Gilbers M, Perry da Câmara L, Prahl Wittberg L, Taccone FS, Malfertheiner MV, Di Nardo M, Swol J, Vercaemst L, Barrett NA, Pappalardo F, Belohlavek J, Belliato M, Lorusso R Tags: Perfusion Source Type: research

Using a quality improvement initiative to reduce acute kidney injury during on-pump coronary artery bypass grafting.
Abstract INTRODUCTION: In response to a perceived high incidence of acute kidney injury following cardiopulmonary bypass at our institution, a quality improvement initiative consisting of a systematic change to a delivered oxygen (DO2) goal-directed perfusion practice was implemented. We sought to maintain DO2 > 270 mL/min/m2 to reduce the incidence of acute kidney injury. METHODS: 'The study population included all patients receiving isolated, non-emergent, on-pump coronary artery bypass grafting from January 2015 through December 2018, excluding patients requiring preoperative hemodi...
Source: Perfusion - June 5, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Katona MA, Walker JL, Das NA, Miller SR, Sako EY Tags: Perfusion Source Type: research

The Great Ormond Street Hospital immunoadsorption method for ABO-incompatible heart transplantation: a practical technique.
This article outlines the practical details required to perform the technique in order to avoid hyperacute rejection. PMID: 32493108 [PubMed - as supplied by publisher] (Source: Perfusion)
Source: Perfusion - June 3, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Issitt R, Crook R, Shaw M, Robertson A Tags: Perfusion Source Type: research