Cohort profile: the Environmental Reproductive and Glucose Outcomes (ERGO) Study (Boston, Massachusetts, USA) -- a prospective pregnancy cohort study of the impacts of environmental exposures on parental cardiometabolic health
Purpose
Pregnancy and the postpartum period are increasingly recognised as sensitive windows for cardiometabolic disease risk. Growing evidence suggests environmental exposures, including endocrine-disrupting chemicals (EDCs), are associated with an increased risk of pregnancy complications that are associated with long-term cardiometabolic risk. However, the impact of perinatal EDC exposure on subsequent cardiometabolic risk post-pregnancy is less understood. The Environmental Reproductive and Glucose Outcomes (ERGO) Study was established to investigate the associations of environmental exposures during the perinatal peri...
Source: BMJ Open - May 8, 2024 Category: General Medicine Authors: Preston, E. V., Quinn, M. R., Williams, P. L., McElrath, T. F., Cantonwine, D. E., Seely, E. W., Wylie, B. J., Hacker, M. R., O'Brien, K., Brown, F. M., Powe, C. E., Bellavia, A., Wang, Z., Tomsho, K. S., Hauser, R., James-Todd, T., the Environmental Repr Tags: Open access, Epidemiology Source Type: research
The efficacy of NIV in patients affected by Rett syndrome with hypoventilation
Rett syndrome is a progressive neurological disorder associated to several comorbidities that contribute significantly to impair lung function. Respiratory morbidity represents a major cause of death in this population. Little is known about the benefit of non-invasive ventilation. (Source: Pediatric Neurology)
Source: Pediatric Neurology - May 8, 2024 Category: Neurology Authors: Francesca Peri, Claudio Cherchi, Maria Beatrice Chiarini Testa, Martino Pavone, Elisabetta Verrillo, Renato Cutrera Tags: Research Paper Source Type: research
Changes in abilities over the initial 12 months of nusinersen treatment for type II SMA
Spinal muscular atrophy (SMA) is an autosomal recessive, progressive neurodegenerative condition resulting from mutations in the survival motor neuron 1 gene (SMN1), leading to the degeneration of α-motor neurons in the spinal cord and brain stem. Historically, the disease is classified into types I-IV, with types I-III of pediatric-onset [1]. Type II SMA, with symptom onset between 6 and 18 months, is characterized by inability to achieve independent standing and walking [2,3]. As part of n atural history, there is a progressive loss of functional abilities that becomes more evident between the age of 5 and 13 years [4-6...
Source: Neuromuscular Disorders - May 8, 2024 Category: Neurology Authors: Giorgia Coratti, Matthew Civitello, Annemarie Rohwer, Francesca Salmin, Allan M Glanzman, Jaqueline Montes, Amy Pasternak, Roberto De Sanctis, Sally Dunaway Young, Tina Duong, Irene Mizzoni, Evelin Milev, Maria Sframeli, Simone Morando, Emilio Albamonte, Tags: Research paper Source Type: research
Prevalence and risk factors associated within 48-hour unplanned paediatric intensive care unit readmissions: An integrative review
Unplanned paediatric intensive care unit (PICU) readmission is associated with increased morbidity/mortality, hospital length of stay, and health service cost and is recognised as a key performance indicator of quality-of-care delivery. However, research evidence on unplanned PICU readmission risk factors is limited, and results were inconsistent across studies. (Source: Australian Critical Care)
Source: Australian Critical Care - May 8, 2024 Category: Nursing Authors: Martina K. Barnwell, Huaqiong Zhou, Simon Erickson Tags: Review paper Source Type: research
Insomnia severity among caregivers of children with type 1 diabetes: A mixed method study
This research was conducted to assess the severity of insomnia experienced by caregivers of children with type 1 diabetes. (Source: Journal of Pediatric Nursing)
Source: Journal of Pediatric Nursing - May 8, 2024 Category: Nursing Authors: Tu ğba Bilgehan, Dilek Uludaşdemir Source Type: research
Self-care deficits reported by school children with cystic fibrosis
Self-care refers to the ability that an individual has or develops to regulate the functioning of the body. Health status and age are factors associated with dependency on, and the need for, someone else to take over self-care. In the present case, there was a self-care deficit. Cystic fibrosis is a chronic disease that occurs in one in 10,000 live births in Brazil, and the affected population in the country is predominantly pediatric (approximately 73%). Support from nursing teams is necessary to improve patients' skills until they can take full responsibility for their self-care. (Source: Journal of Pediatric Nursing)
Source: Journal of Pediatric Nursing - May 8, 2024 Category: Nursing Authors: Thiago Doria Rego, Juliana Rezende Montenegro Medeiros de Moraes, Ivone Evangelista Cabral, Tania Vignuda de Souza Source Type: research
Post-acute Sequelae of SARS-CoV-2 Infection and Its Impact on Adolescents and Young Adults
This review discusses the varying definitions for post-acute sequelae of SARS CoV-2 infection (PASC) in adolescents and young adults (AYAs), symptom profiles of AYAs with PASC, and assessment and management strategies when AYAs present with symptoms concerning for PASC. Additionally, it reviews the impact that PASC can have on AYAs and includes strategies for providers to support AYAs with PASC. Finally, it concludes with a discussion around equity in the care of AYAs with possible PASC. (Source: Pediatric Clinics of North America)
Source: Pediatric Clinics of North America - May 8, 2024 Category: Pediatrics Authors: Camille A. Broussard, Alba Azola, Peter C. Rowe Source Type: research
Disordered Eating/Eating Disorders in Adolescents
The coronavirus disease 2019 pandemic was as tressful time for adolescents, with increased isolation, loss of routines, and changes in access to medical care. In this setting, the medical system saw a significant rise in the number of adolescents seeking care for eating disorders, as well as increased severity of patient presentation. Telehealth treatment for eating disorders was a unique shift during the pandemic, with some benefits but not universally positive experiences among patients, families and providers. (Source: Pediatric Clinics of North America)
Source: Pediatric Clinics of North America - May 8, 2024 Category: Pediatrics Authors: Sydney M. Hartman-Munick, Suzanne Allen, Anne Powell Source Type: research
Top ten reviewers 2023
While the origin of the peer-review process dates back to the mid 18th Century, it was not fully adopted by mainstream journals within North America until the mid 20th Century. Although imperfect, it certainly lays the foundation for maintaining the integrity of scientific publication. We at the JPU, realize the tremendous time commitment involved with the peer review process and would like to extend our appreciation to all reviewers over the last year. Simply put, we could not exist without your assistance and personal sacrifice to provide constructive feedback to authors that assures the highest quality of scientific pub...
Source: Journal of Pediatric Urology - May 8, 2024 Category: Urology & Nephrology Source Type: research
Cardiac output calculation using the Liljestrand and Zander formula: is this method applicable during immediate transition after birth? — A post hoc analysis
Conclusion: The present study demonstrates high comparability of COest/adj LaZ and CO-bioimpedance in neonates during immediate transition after birth, suggesting that cardiac output can be derived in a cost-effective and feasible manner if other methods are not available.What is Known:• Echocardiography is considered the gold standard for non-invasive CO evaluation, but its feasibility during the immediate transition period is limited.What is New:• Non-invasive methods such as CO-bioimpedance for cardiac output (CO) measurement and the Liljestrand and Zander (LaZ) formula for estimating CO offer promising alternatives...
Source: European Journal of Pediatrics - May 8, 2024 Category: Pediatrics Source Type: research
Recurrent Mononeuropathy, Stroke and Deafness in a Teenage Boy: Authors ’ Reply
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - May 8, 2024 Category: Pediatrics Source Type: research
Genetically Confirmed Case of Aspartylglycosaminuria (AGU)
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - May 8, 2024 Category: Pediatrics Source Type: research
Assessment of aortic dilatation in Chinese children and adolescents with Turner syndrome: a single center experience
This study aimed to investigate the... (Source: BMC Pediatrics)
Source: BMC Pediatrics - May 8, 2024 Category: Pediatrics Authors: Wei Su, Longwei Sun, Zhuoguang Li, Xia Liu, Longjiang Zhang, Xiu Zhao, Shumin Fan, Boning Li, Ying Xie, Weiwei Xiao and Zhe Su Tags: Research Source Type: research
Functional connectivity is linked to working memory differences in children with reading learning disability
Reading learning disability (RLD) is characterized by a specific difficulty in learning to read that is not better explained by an intellectual disability, lack of instruction, psychosocial adversity, or a neu... (Source: BMC Pediatrics)
Source: BMC Pediatrics - May 8, 2024 Category: Pediatrics Authors: Rodrigo Flores-Gallegos, Thal ía Fernández, Sarael Alcauter, Erick Pasaye, Lucero Albarrán-Cárdenas, Bertha Barrera-Díaz and Paulina Rodríguez-Leis Tags: Research Source Type: research
Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) as part of the clinical presentation of pediatric multiple sclerosis, successfully treated with therapeutic plasma exchange
Pediatric multiple sclerosis (MS) refers to MS cases with onset before the age of 18. The pathophysiology and presentation of pediatric MS is similar to adult cases. Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) is a rare brainstem disorder characterized by exotropia, bilateral impairment of adduction, dissociated nystagmus of the abducting eye, vertical gaze-evoked nystagmus, and impaired vertical vestibulo-ocular reflex. While WEBINO has been reported in adult MS, to our knowledge, its occurrence in pediatric MS is not documented. (Source: Pediatric Neurology)
Source: Pediatric Neurology - May 8, 2024 Category: Neurology Authors: Sara Shakin, Michael Altman, Jennie Hart, Sarah Hopkins, Peggy Lazerow, J. Alfredo Caceres Tags: Short Communication Source Type: research
