Cyclosporine Anionic and Cationic Ophthalmic Emulsions in Dry Eye Disease: A Literature Review.
CONCLUSIONS: Both formulations are effective for the treatment of moderate-to-severe DED and are well tolerated. PMID: 32469256 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 31, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Detection of SARS-CoV-2 in Human Retinal Biopsies of Deceased COVID-19 Patients.
CONCLUSION: Viral RNA of SARS-CoV-2 is detectable in the retina of COVID-19 patients. PMID: 32469258 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 31, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Systemic Miltefosine as an Adjunct Treatment of Progressive Acanthamoeba Keratitis.
CONCLUSION: Oral MLT may be a viable adjunctive therapy for recalcitrant AK; however, its use may be associated with a severe inflammatory reaction. Further studies are needed to evaluate its efficacy and variable clinical response. PMID: 32469616 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 31, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Efficacy of Adalimumab in Non-Infectious Uveitis Across Different Etiologies: A Post Hoc Analysis of the VISUAL I and VISUAL II Trials.
CONCLUSIONS: Treatment failure risk was lower in patients with idiopathic noninfectious uveitis receiving adalimumab versus those receiving placebo. PMID: 32469621 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 31, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Direct Immunofluorescence Findings in 145 Consecutive Patients Receiving a Conjunctival Biopsy for Cicatrizing Conjunctivitis.
Authors: Kneiber D, Kowalski EH, Kroloff M, Patel PM, Jones VA, Tu EY, Sugar J, Aronson I, Amber KT PMID: 32469634 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 31, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Peripheral Capillary Non-perfusion in Birdshot Retinochoroiditis: A Novel Finding on Ultra-widefield Fluorescein Angiography.
CONCLUSIONS: Peripheral ischemia may present in eyes with chronic inflammation as seen in BRC but does not seem to progress to neovascular complications. This is likely to be more common than suspected and has now become evident following the advent of UWFFA. ABBREVIATIONS: HLA-A29: Human leukocyte antigen - A29; FFA: Fundus fluorescein angiography; OCT: Optical coherence tomography; ICGA: Indocyanine green angiography; UWF: Ultra-wide field; UWFFA: Ultra-wide field fluorescein angiography; CNP: Capillary non-perfusion. PMID: 32469666 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 31, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

In Vivo Analysis and Comparison of Anterior Segment Structures of Both Eyes in Unilateral Herpetic Anterior Uveitis.
Conclusion: SCA found similar on both sides. DIL is the most common iris feature of affected eyes. PMID: 32469669 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 31, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Correction.
Authors: PMID: 32469681 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 31, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Anterior Uveitis Due to Intracameral Moxifloxacin: A Case Report.
CONCLUSION AND IMPORTANCE: We present the second published case worldwide about anterior uveitis secondary to intracameral moxifloxacin, which may rarely cause hypertensive uveitis that may be confused with viral uveitis. This provides evidence on the importance of postoperative follow-up by the surgeon for an early referral and treatment of these cases. PMID: 32469689 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 31, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

A Validation Study of the Revised Diagnostic Criteria from the International Workshop on Ocular Sarcoidosis at a Single Institute in Japan.
CONCLUSION: The revised IWOS criteria are useful in Japanese patients, but could possibly be improved by modifying the criterion of presumed or probable OS. PMID: 32469694 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 31, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Effect of In Vivo Expansion of Regulatory T Cells with IL-2/anti-IL-2 Antibody Complex Plus Rapamycin on Experimental Autoimmune Uveoretinitis.
Conclusions: These findings suggest the potential limitations of IL-2 complex or IL-2 complex/rapamycin during EAU. PMID: 32459545 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 29, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

The Use of Optical Coherence Tomography Angiography in the Diagnosis of Inflammatory Type 1 Choroidal Neovascularization Secondary to Tuberculosis: A Case Report.
Conclusion: OCTA may be superior to ICGA in the detection of CNV secondary to inflammatory situations. PMID: 32459550 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 29, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Epstein-Barr Virus and the Eye.
Authors: Cunningham ET, Zierhut M PMID: 32462995 [PubMed - in process] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 29, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Tubulointerstitial Nephritis and Uveitis Syndrome: Characterization of Clinical Features.
CONCLUSIONS: TINU occurs in all age groups. Posterior segment manifestations are common. Most patients required systemic steroid therapy, with a significant number requiring long-term systemic immunomodulation. Careful fundus examination is required on all patients with TINU. PMID: 32463299 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 29, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Atypical Keratic Precipitates in Fuchs Uveitis.
CONCLUSION: Ophthalmologists should be aware that FU can manifest with atypical KPs in a minority of patients to prevent erroneous diagnosis and unnecessary treatments. PMID: 32463307 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 29, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Role of Ultra-widefield Imaging in Eales' Disease: A Case Series.
CONCLUSION: Ultra-widefield imaging is a very helpful tool in the management of a patient with Eales'disease. PMID: 32463328 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 29, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

COVID-19 and Eye Problems.
Authors: Mungmunpuntipantip R, Wiwanitkit V PMID: 32463341 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 29, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Cataract Surgery in the Setting of Scleritis.
CONCLUSION: In addition to providing a distinct pattern of cataract, index study showed that long-term control of scleral inflammation prior to the cataract surgery remains the primary requisite for the successful outcome. PMID: 32463347 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 29, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Pediatric Uveitis in a Referral Center in North Part of Turkey.
Authors: Eser-Ozturk H, Sullu Y Abstract Purpose: To analyze the demographic characteristics, clinical features, ocular complications, and visual outcome of pediatric patients with uveitis.Methods: Retrospective evaluation of medical records.Results: The study included 156 eyes of 93 patients. Fifty-three patients were female and 40 were male. Mean age at onset of the uveitis was 9.54 ± 4.29 years. The mean follow-up period was 29.88 ± 28.97 months. Anterior uveitis (49.5%) was the most common anatomic type followed by panuveitis (21.5%), intermediate uveitis (18.3%), and...
Source: Ocular Immunology and Inflammation - May 29, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Primary Vitreoretinal Lymphoma in HIV Infection.
Conclusions: Ophthalmologists should consider the diagnosis of PVRL in HIV-positive individuals who present with intermediate or posterior uveitis. PMID: 32453669 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 28, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Combination of Intravenous Methotrexate and Methylprednisolone Therapy in the Treatment of Severe Ocular Inflammatory Diseases.
Conclusion: Intravenous methotrexate and methylprednisolone infusions can be an effective method of treatment in patients with severe, sight-threatening ocular inflammatory conditions. PMID: 32406782 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 16, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Diffuse Phlebitis in Patients with Syphilitic Outer Retinopathy.
Conclusion: FA is especially important for differentiating syphilitic outer retinopathy from AZOOR. Timely diagnosis and treatment with penicillin and cautious use of steroid usually lead to favorable prognosis. PMID: 32406792 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 16, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Retinal Microcirculation Defects on OCTA Correlate with Active Inflammation and Vision in Vogt-Koyanagi-Harada Disease.
Authors: Liang A, Zhao C, Jia S, Gao F, Han X, Pei M, Qu Y, Xiao J, Zhang M Abstract Purpose: To analyze quantitative OCT-angiography (OCTA) measurements of Vogt-Koyanagi-Harada (VKH) disease at different disease stages.Methods: OCTA scans of 110 VKH patients in acute uveitic, convalescent and chronic recurrent stage were reviewed; posterior uveitis recurrent cases were excluded. Superficial and deep capillary plexus (SCP and DCP) vascular densities (VD) and subfoveal choroidal thickness (SFCT) were compared.Results: DCP VD was significantly lower and SFCT higher in VKH than normal controls (NC) in all 3 stages (all p
Source: Ocular Immunology and Inflammation - May 16, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Viral Acute Anterior Uveitis: Clinical Signs Useful for Differential Diagnosis.
Conclusion: Unilaterality, IOP≥24 mmHg and iris atrophy are significant predictors of possible viral etiology in AAU. PMID: 32407185 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 16, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Comparison of Topical Pigment Epithelium-Derived Factor (PEDF) with Topical Bevacizumab for Accelerating the Regression of Corneal Neovascularization in an Experimental Model of Rabbit Corneal Angiogenesis.
Authors: Mahmoudzadeh R, Heidari-Keshel S, Mehrpour M, Asadi Amoli F, Aghajanpour L, Lashay A Abstract Purpose: To evaluate the anti-angiogenic effect of topical administration of Pigment epithelium-derived factor (PEDF) on the reduction of corneal neovascularization (NV) in comparison to topical Bevacizumab.Methods: 18 eyes of 18 New Zealand rabbits were enrolled. Corneal NV was induced by a 7-0 silk suture. After suture removal, rabbits were randomly divided into three groups. In every group, one eye randomly treated with topical bevacizumab or topical PEDF or saline for 14 days. The area and length of neova...
Source: Ocular Immunology and Inflammation - May 16, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Escalation to Weekly Adalimumab for the Treatment of Ocular Inflammation.
Conclusion: Our series suggests that the escalation of ADA can be a useful strategy for treating recalcitrant ocular inflammation, but may not be adequate to treat refractory CME. PMID: 32407246 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 16, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Animal Models of Ocular Tuberculosis: Implications for Diagnosis and Treatment.
Authors: Basu S, Rao N, Elkington P Abstract The pathogenesis of ocular tuberculosis (TB) has remained unclear due to the challenges of performing mechanistic studies on clinical samples. Animal models have the potential to bridge these gaps by providing information about ocular dissemination and localization of mycobacteria, innate and adaptive immune response, and granuloma formation in the eye. Here, we critically review various animal models of ocular TB from the early 20th century to date and derive novel insights into pathogenesis of ocular TB that have direct implications on the diagnosis and treatment of th...
Source: Ocular Immunology and Inflammation - May 16, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

The Rs12569232 SNP Association with Vogt-Koyanagi-Harada Disease and Behcet's Disease is Probably Mediated by Regulation of Linc00467 Expression.
Conclusions: The rs12569232 association with VKH disease and BD may be mediated via regulating the expression of linc00467. PMID: 32400232 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 15, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Scleral Inflammation around Collector Channels in Eyes with Primary Open-Angle Glaucoma.
Conclusion: In POAG a diverse cellular infiltration exists around the CCs in the vast majority of biopsies. This could have major diagnostic and therapeutic consequences for the treatment of POAG.Abbreviations: POAG: primary open-angle glaucoma; CC: collector channel; AH: aqueous humor; TM: trabecular meshwork; SC: Schlemm's canal; HE: hematoxylin & eosin; APC: antigen-presenting cell. PMID: 32400241 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 15, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

A Case Report of Sweet's Syndrome with Panuveitis and Rhegmatogenous Retinal Detachment.
Conclusion: The association of bilateral uveitis with Sweet's syndrome has been described in this report. PMID: 32394773 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 13, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

The Changing Global Epidemic of HIV and Ocular Disease.
Conclusion: The changing epidemic of ocular disease in HIV-infected patients warrants close monitoring and identification of interventions that can help reduce the imminent burden of disease. PMID: 32396027 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 13, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Multimodal Imaging in Ocular Sarcoidosis.
Conclusions: This review article highlights the role of fundus fluorescein angiography (FA), indocyanine green angiography (ICG), optical coherence tomography (OCT), and optical coherence tomography angiography (OCTA) in the diagnosis and management of ocular sarcoidosis. This review article highlights the role of fundus fluorescein angiography (FA), indocyanine green angiography (ICG), optical coherence tomography (OCT), and optical coherence tomography angiography (OCTA) in the diagnosis and management of ocular sarcoidosis. PMID: 32396030 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 13, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Lessons in Digital Epidemiology from COTS-1: Coordinating Multicentre Research across 10 Countries Using Operational and Technology Innovation to Overcome Funding Deficiencies.
Conclusion: The final output from this effort was an in-depth retrospective analysis to facilitate the design of future prospective investigations on ocular TB and develop best practice guidelines. PMID: 32320326 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 23, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

COVID-19: Limiting the Risks for Eye Care Professionals.
Authors: Sadhu S, Agrawal R, Pyare R, Pavesio C, Zierhut M, Khatri A, Smith JR, de Smet MD, Biswas J Abstract After the outbreak of the disease COVID-19, it has reached pandemic proportions within a very short time. It is mainly transmitted human-to-human through direct contact with secretions from an infected person or through inhalation of droplets containing SARS-CoV-2. It is controversial whether the virus may be transmitted via tears. Exposed ocular surface can serve as a gateway in transmission and acquiring respiratory diseases. Considering the reported cases on healthcare workers indicating nosocomial trans...
Source: Ocular Immunology and Inflammation - April 22, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

An Algorithm for the Diagnosis of Beh ├žet Disease Uveitis in Adults.
Conclusion: This study provides a diagnostic tree for BD uveitis that needs to be validated in future studies. PMID: 32286112 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 16, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Analysis of Foveal Microvascular Abnormalities in Patients with Systemic Lupus Erythematosus Using Optical Coherence Tomography Angiography.
Authors: An Q, Gao J, Liu L, Liao R, Shuai Z Abstract Purpose: To analyze the abnormalities of foveal microvasculature in patients with systemic lupus erythematosus (SLE).Methods: A cross-sectional study of 41 eyes of patients diagnosed with SLE and 40 eyes of healthy controls. Sections measuring 6 mm×6 mm centered on the fovea were obtained using optical coherence tomography angiography (OCTA).Results: The area and perimeter of foveal avascular zone (FAZ) in SLE patients were greater than those in controls (both p
Source: Ocular Immunology and Inflammation - April 16, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Acute Bilateral Anterior Uveitis following Cyclophosphamide/ Bortezomid/Dexamethasone (CyBorD) Protocol in a Newly Diagnosed Multiple Myeloma Patient with Concomitant Use of Zoledronic Acid.
Conclusion: Our case mirrored uveitis cases with either masquerade syndrome due to Multiple Myeloma or following Zoledronic acid infusion, despite concomitant usage of Dexamethasone and Cyclophosphamide. Three consecutive rechallenges were performed without any topical prophylactic treatment and with no relapse of signs or symptoms. PMID: 32286130 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 16, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Incidence and Risk Factors for Blindness in Uveitis: A Nationwide Cohort Study from 2002 to 2013.
Conclusions: Low household income and Behçet's disease influence the risk of blindness in uveitis patients. These findings will help in assessing blindness-related socioeconomic burdens and planning health-care strategies for uveitis patients. PMID: 32293927 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 16, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Clinical Profile in Genetically Proven Blau Syndrome: A Case Series from South India.
Conclusions: Blau syndrome is underreported in India. This is the largest case series of genetically proven Blau syndrome from South India and highlights the clinical profile of Blau syndrome seen in India. PMID: 32293936 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 16, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

An Uncommon Concurrence of Cytomegalovirus Retinitis and Corneal Endotheliitis in an Immunocompromised HIV-Negative Patient.
Conclusion: CMV retinitis may occur in HIV-negative immunocompromised individuals, but CMV endotheliitis generally appears in the immunocompetent. It is a rare combination of CMV retinitis and endotheliitis in this patient. PMID: 32275171 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 12, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Evaluation of Ultrasound Biomicroscopy Combined with Color Doppler Flow Imaging in the Diagnosis of Primary Lacrimal Canaliculitis.
Conclusion: Ultrasonography is a valuable tool to assist the diagnosis of canaliculitis.(Clinical trial registration number: ChiCTR1900025411). PMID: 32275172 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 12, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Assessment of the Readability, Availability, and Quality of Online Patient Education Materials Regarding Uveitis Medications.
Conclusions: Online information regarding uveitis medications lacks accountability and is not written at an appropriate level for the average patient. PMID: 32275173 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 12, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Post-cataract Surgery Fungal Endophthalmitis: Management Outcomes and Prognostic Factors.
Conclusions: Corneal involvement in addition to endophthalmitis and the presence of Aspergillus terreus were found to be poor prognostic markers. PMID: 32275174 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 12, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Corneal Microstructural Changes by Confocal Microscopy in Vernal Keratoconjunctivitis Patients Treated with Topical Cyclosporine.
Conclusions: IVCM is a valuable tool to evaluate the dynamic corneal changes in VKC before and after treatment with CsA. PMID: 32275180 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 12, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Contralateral Eye Involvement and Retinal Detachment in Patients with Cytomegalovirus Retinitis Treated with Intravitreous Ganciclovir.
Conclusion: Eyes treated with intravitreous ganciclovir experienced retinal detachment at a rate similar to other populations treated with systemic antivirals. The risk of contralateral eye involvement was relatively high during the first 3 months after initial diagnosis despite the institution of antiretroviral therapy. PMID: 32275186 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 12, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Non-invasive Instrument-Based Tests for Quantifying Anterior Chamber Flare in Uveitis: A Systematic Review.
Conclusion: LFP shows moderate to strong correlation with clinician grading and aqueous protein concentration. LFP could be a superior reference test compared to clinician AC flare grading for validating new index tests. PMID: 32255392 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 9, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Systemic Immunosuppression Is Highly Effective in the Long-term Control of Inflammatory non-infectious Uveitic Choroidal Neovascularization: A Comparative Study.
Authors: Neri P, Pichi F, Pirani V, Arapi I Abstract Purpose: To compare immediate versus delayed introduction of immunosuppressives for naive noninfectious inflammatory choroidal neovascularization (iCNV).Methods: a retrospective, consecutive, comparative, interventional case series of patients with a diagnosis of inflammatory CNV and a minimum follow of 36 months. Patients were divided into two groups: Group A received Immunosuppressives if needed, while Group B since baseline. Both groups received systemic steroids and intravitreal ranibizumab since baseline. Primary end point was to compare the BCVA outcom...
Source: Ocular Immunology and Inflammation - April 9, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Efficacy of Topical Ivermectin for the Treatment of Cutaneous and Ocular Rosacea.
Conclusion: Topical ivermectin cream 1% given daily is an effective and safe therapy against rosacea. PMID: 32255398 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 9, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Vitamin D and Ocular Inflammation.
Authors: Cunningham ET, Sobrin L, Hall AJ, Zierhut M PMID: 32255412 [PubMed - in process] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 9, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

The Relationship between Ocular Vascular Changes and the Levels of Malondialdehyde and Vascular Endothelial Growth Factor in Patients with Inflammatory Bowel Disease.
Authors: Sengul Samanci N, Poturoglu S, Samanci C, Ustabasioglu FE, Koldas M, Duman AE, Ormeci AC Abstract Background: We evaluated ocular hemodynamic changes, malondialdehyde(MDA) and vascular endothelial growth factor (VEGF) levels in patients with IBD.Methods: We used ocular color Doppler ultrasonography to analyze 56 eyes with Crohn's disease (CD), 62 eyes with ulcerative colitis (UC), 68 eyes of healthy volunteers. We measured peak systolic velocity (PSV),end-diastolic velocity (EDV),and the resistivity index (RI) of ophthalmic artery (OA) and central retinal artery (CRA). MDA and VEGF levels were measured in ...
Source: Ocular Immunology and Inflammation - April 9, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research