Vogt-Koyanagi-Harada Syndrome in a Canadian First Nations Population
Conclusions: VKH may cause potentially severe uveitis in this population. Comorbidities including tuberculosis and diabetes, in addition to unique cultural, linguistic and geographic factors, may necessitate complex, individualized management strategies.PMID:33621146 | DOI:10.1080/09273948.2020.1849737 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 23, 2021 Category: Allergy & Immunology Authors: Michael T Kryshtalskyj Mili Roy Source Type: research

Contemporaneous Risk Factors for Visual Acuity in Non-Infectious Uveitis
Ocul Immunol Inflamm. 2021 Feb 23:1-8. doi: 10.1080/09273948.2020.1828493. Online ahead of print.ABSTRACTINTRODUCTION: We evaluated the associations of clinical and demographic characteristics with visual acuity (VA) with over 5 years in a subspecialty noninfectious uveitis population.METHODS: Retrospective data from 5,530 noninfectious uveitis patients were abstracted by expert reviewers, and contemporaneous associations of VA with demographic and clinical factors were modeled.RESULTS: Patients were a median of 41 years old, 65% female, and 73% white. Eyes diagnosed ≥5 years prior to cohort entry had worse VA (-1.2 lin...
Source: Ocular Immunology and Inflammation - February 23, 2021 Category: Allergy & Immunology Authors: Maxwell Pistilli Sapna S Gangaputra Siddharth S Pujari Douglas A Jabs Grace A Levy-Clarke Robert B Nussenblatt James T Rosenbaum H Nida Sen Eric B Suhler Jennifer E Thorne Nirali P Bhatt C Stephen Foster Hosne Begum Tonetta D Fitzgerald Kurt A Dreger John Source Type: research

Vogt-Koyanagi-Harada Syndrome in a Canadian First Nations Population
Conclusions: VKH may cause potentially severe uveitis in this population. Comorbidities including tuberculosis and diabetes, in addition to unique cultural, linguistic and geographic factors, may necessitate complex, individualized management strategies.PMID:33621146 | DOI:10.1080/09273948.2020.1849737 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 23, 2021 Category: Allergy & Immunology Authors: Michael T Kryshtalskyj Mili Roy Source Type: research

Contemporaneous Risk Factors for Visual Acuity in Non-Infectious Uveitis
Ocul Immunol Inflamm. 2021 Feb 23:1-8. doi: 10.1080/09273948.2020.1828493. Online ahead of print.ABSTRACTINTRODUCTION: We evaluated the associations of clinical and demographic characteristics with visual acuity (VA) with over 5 years in a subspecialty noninfectious uveitis population.METHODS: Retrospective data from 5,530 noninfectious uveitis patients were abstracted by expert reviewers, and contemporaneous associations of VA with demographic and clinical factors were modeled.RESULTS: Patients were a median of 41 years old, 65% female, and 73% white. Eyes diagnosed ≥5 years prior to cohort entry had worse VA (-1.2 lin...
Source: Ocular Immunology and Inflammation - February 23, 2021 Category: Allergy & Immunology Authors: Maxwell Pistilli Sapna S Gangaputra Siddharth S Pujari Douglas A Jabs Grace A Levy-Clarke Robert B Nussenblatt James T Rosenbaum H Nida Sen Eric B Suhler Jennifer E Thorne Nirali P Bhatt C Stephen Foster Hosne Begum Tonetta D Fitzgerald Kurt A Dreger John Source Type: research

Tryptophan as a Safe Compound in Topical Ophthalmic Medications: < em > In Vitro < /em > and < em > In Vivo < /em > Studies
Conclusions: TRP had no influence on the cellular cytoskeleton but induced a significant pseudopodia projection in both epithelia. TRP did not influence corneal re-epithelization in vivo. TRP was not toxic for corneal and conjunctival epithelia.PMID:33616466 | DOI:10.1080/09273948.2020.1856883 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 22, 2021 Category: Allergy & Immunology Authors: Anna Matysik-Wo źniak Waldemar A Turski Monika Turska Roman Paduch Miros ław Łańcut Pawe ł Piwowarczyk Miros ław Czuczwar Robert Rejdak Source Type: research

Epidemiology of Viral Induced Anterior Uveitis
Conclusion: HSV, VZV are prevalent worldwide. CMV is more frequent in Asia, and rubella in the West. However, due to globalization and air travel, HTLV-1, Chikungunya, Dengue and Ebola may become important causes of VAU across the world.PMID:33617392 | DOI:10.1080/09273948.2020.1853177 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 22, 2021 Category: Allergy & Immunology Authors: Aleksandra Radosavljevic Mamta Agarwal Soon Phaik Chee Manfred Zierhut Source Type: research

Melanocortin 5 Receptor Expression and Recovery of Ocular Immune Privilege after Uveitis
Conclusion: α-MSH treatment of EAU mediates a MC5r-dependent recovery of RPE suppression of phagolysosome activation in macrophages possibly altering antigen processing and presentation. Also, MC5r-expression helps protect the retina from inflammatory damage. In addition, MC5r-expression is important in the homeostatic maintenance of phagosome-maturation within macrophages.PMID:33617397 | DOI:10.1080/09273948.2020.1849735 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 22, 2021 Category: Allergy & Immunology Authors: Tat Fong Ng Ambika Manhapra David Cluckey Yoona Choe Srujan Vajram Andrew W Taylor Source Type: research

< em > Serratia Marcescens < /em > Endophthalmitis and Bacteraemia following Complicated Cataract Surgery
Ocul Immunol Inflamm. 2021 Feb 22:1-2. doi: 10.1080/09273948.2020.1846060. Online ahead of print.ABSTRACTA 93-year-old male presented with left eye pain, fever and loss of vision two days after complicated cataract surgery. A diagnosis of Serratia marcescens endophthalmitis and systemic bacteremia was made after the organism was identified on vitreous and peripheral blood cultures. This case demonstrates that an aggressive intraocular infection can lead to bacteremia.PMID:33617399 | DOI:10.1080/09273948.2020.1846060 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 22, 2021 Category: Allergy & Immunology Authors: Riyaz Bhikoo Matt Blakiston William Cunningham Sinead McCarthy Amanda Charlton Mark Donaldson Source Type: research

Late Contralateral Recurrence of Unilateral Acute Idiopathic Maculopathy: Adaptive Optics Findings
CONCLUSION: This would explain the acute clinical presentation of UAIM, followed by a spontaneous, partial, recovery, with a relative scotoma remaining over time.PMID:33617409 | DOI:10.1080/09273948.2020.1821897 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 22, 2021 Category: Allergy & Immunology Authors: C éline Faure Pauline Cognard Matthieu P Robert Source Type: research

Review of the Current Literature and Our Experience on the Value of OCT-angiography in White Dot Syndromes
CONCLUSIONS: We confirmed that OCT-A contributes new information on the physiopathology of white dot syndromes and inflammatory chorioretinopathies, notably on whether or not the choriocapillaris is involved. Comparing the OCT-A features allowed us to suggest that both APMPPE and SLC might be part of the same spectrum of inflammatory disease with primary involvement at the level of the choriocapillaris and secondary RPE damage.PMID:33617412 | DOI:10.1080/09273948.2020.1837185 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 22, 2021 Category: Allergy & Immunology Authors: C éline Mebsout-Pallado Rapha ëlle Orès C éline Terrada Kunal K Dansingani Jay Chhablani Andrew W Eller Joseph N Martel Alexander Anetakis Jean C Harwick Evan L Waxman Denise S Gallagher Colin Prensky Chad Indermill Neila Sedira Emmanuel H éron Miche Source Type: research

Multiple Faces of Eyelid Involvement in Sarcoidosis.
Conclusion: Although eyelid involvement in sarcoidosis is uncommon, different forms of presentation, including destructive lesions, can be observed. PMID: 33606589 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 20, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Optic Nerve Head Parameters and Peripapillary Retinal Nerve Fiber Layer Thickness in Patients with Coronavirus Disease 2019.
Conclusion: Patients recovered from COVID-19 had unremarkable alterations in the peripapillary RNFL thickness. Abbreviations: ONH: Optic Nerve HeadRNFL: Retinal Nerve Fiber LayerSD-OCT: Spectral-Domain Optical Coherence TomographyCOVID-19: Coronavirus Disease 2019SARS-CoV-2: Severe Acute Respiratory Syndrome Coronavirus 2CNS: Central Nervous SystemACE: Angiotensin-Converting EnzymeRT-PCR: Reverse Transcription-Polymerase Chain Reaction. PMID: 33606593 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 20, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Drug-induced Sarcoid Uveitis with Biologics.
Conclusions: Biologic treatment-induced uveitis often presents as granulomatous disease. PMID: 33596386 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 19, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

The Usefulness of Monocyte-to-High Density Lipoprotein and Neutrophil-to-Lymphocyte Ratio in Diabetic Macular Edema Prediction and Early anti-VEGF Treatment Response.
Conclusion: MHR and NLR were simple and cost-effective biomarkers to predict DME. Moreover, higher NLR may contribute to poor CRT outcomes. PMID: 33596398 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 19, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Recent Clinical Features of Intraocular Inflammation in Hokkaido, Japan - Comparison with the Previous Decade.
CONCLUSION: Although the order of the top four etiologies was the same in the two surveys, the rate of sarcoidosis increased and that of Behçet's disease decreased. PMID: 33571416 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 13, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Clinical Characteristics and Outcomes of Short-term Repeat Corneal Transplantation.
Authors: Chen X, Li T, Qi X, Shi W, Gao H Abstract PURPOSE: To explore the primary indications, direct causes and graft survival of short-term repeat keratoplasty. METHODS: An analytical cross-sectional study. RESULTS: The primary indications for keratoplasty were infectious keratitis (67.9%) and immune keratopathy (12.8%). The direct causes of graft failure were infectious ulcer (43.6%) and recurrence (30.8%). Pre-operative hypopyon (P = 0.017, HR = 1.757) and use of decellularized porcine corneas as grafts (P = 0.005, HR = 2.690) were independent risk factors for graft failure. The Kaplan-Meier analysis r...
Source: Ocular Immunology and Inflammation - February 10, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Efficacy and Safety of Adalimumab Therapy for the Treatment of Non-infectious Uveitis: Efficacy comparison among Uveitis Aetiologies.
Conclusion: Adalimumab is efficacious and safe for the treatment of patients with Non-infectious uveitis. Differences in the efficacy of adalimumab treatment may exist between patients with Vogt-Koyanagi-Harada disease/sympathetic ophthalmia and patients with Behçet's disease. PMID: 33560160 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 10, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Severe Inflammatory Response in a Patient on Oral Miltefosine for Acanthamoeba Keratitis.
Authors: Si Z, Veldman PB, Reidy JJ, Farooq AV PMID: 33560165 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 10, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Ocular Toxoplasmosis after Exposure to Wild Game.
Conclusions: Contact with wild game is a potential source of primary ocular toxoplasmosis in immunocompetent adults. Hunters and consumers of rare game are at risk of serious ocular disease and appropriate contact precautions and cooking may reduce this complication. PMID: 33560166 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 10, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Comparison of topical omega-3 fatty acids with topical sodium hyaluronate after corneal crosslinking : Short term results.
Conclusion: Topical omega 3 increases tear film stability more prominent than sodium hyaluronate following crosslinking. PMID: 33560170 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 10, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Difference in Host Immune response to Methicillin-Resistant and Methicillin Sensitive Staphylococcus aureus (MRSA and MSSA) Endophthalmitis.
CONCLUSIONS: MRSA strain can induce an exacerbated immune response in retinal cells. Giving clues for potential targets in immunomodulatory therapies. PMID: 33560179 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 10, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Investigation of the Demodex Lid Infestation with in Vivo Confocal Microscopy versus Light Microscopy in Patients with Seborrheic Blepharitis.
Conclusion: KOH was found to be superior in terms of the quantification of mites compared to alcohol and IVCM. PMID: 33560183 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 10, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Incidence of Fungal Infection in Positive Donor Rim Cultures after Corneal Transplantation.
CONCLUSIONS: This study adds to the growing data on the low rate of fungal keratitis and endophthalmitis after a corneal transplant, even in the case of positive rim cultures. This study also suggests that positive rim cultures do not advance the risk of postoperative fungal infection in the recipient. PMID: 33560899 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 10, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Granulocyte Colony Stimulating Factor-induced Immune Recovery Uveitis Associated with Cytomegalovirus Retinitis in the Setting of Good Syndrome.
In this report, we present a patient with Good syndrome who developed IRU secondary to CMV retinitis. PMID: 33561367 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 10, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Iris Manifestations in Inadequately Treated Chronic Recurrent Vogt-Koyanagi-Harada Disease.
Conclusion: Uncontrolled bilateral diffuse granulomatous stromal iris inflammation leads to subsequent depigmentation, transillumination defects and atrophy, beginning in the peripheral iris. Sphincter pupillae is initially spared but complete iris atrophy may develop. PMID: 33561370 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 10, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

The Role of Radiotherapy in Orbital Pseudotumor: A Systematic Review of Literature.
Conclusions: Radiotherapy seemed to achieve good response rates however, in most of the studies, inclusion criteria and outcome parameters are not uniform and therefore the results are difficult to compare. Often important parameters such as chronic pain and permanent functional deficits are not assessed in the outcome. Therefore, prospective studies, with good cohort characteristics and a clear definition of the outcome, are required. PMID: 33561371 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 10, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Atypical Noninfectious Surgically Induced Necrotizing Scleritis in a Child.
We present a case of unilateral surgically induced scleral necrosis resulting in complete loss of left inferior rectus muscle and muscle sheath in a child 2 weeks after uneventful bilateral strabismus surgery for hypertropia. PMID: 33544632 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 7, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Ocular Co-infection with Mycobacterium Tuberculosis and Toxoplasma Gondii in an Immunocompetent Patient - A Case Report.
Conclusion: Ocular tuberculosis and toxoplasmosis can not only mimic each other but also present as co-infection in rare cases. PMID: 33544637 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 7, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Allergy and Dry Eye Disease.
Authors: Leonardi A, Modugno RL, Salami E Abstract Ocular allergy (OA) and dry eye disease (DED) are the most common ocular surface disorders with a potential severe impact on the patient's quality of life. OA and DED may coexist and have a significant clinical overlap. Therefore, clinical features commonly believed to be distinctive of OA or DED may be sometimes insufficient for a differential diagnosis. Alterations of the tear film, epithelial barrier, and corneal innervation are described in OA and can pave the way to DED. Conversely, DED may facilitate or worsen allergic reactions in predisposed (atopic) patien...
Source: Ocular Immunology and Inflammation - February 7, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Use of Short-wave Blue Fundus Autofluorescence to Detect and Monitor Acute Regional Outer Retinopathy in Punctate Inner Choroidopathy.
Conclusions: Symptomatic acute regional outer retinopathy in PIC, manifesting as hyperautofluorescence and EZ loss, is easily identifiable using widefield FAF imaging. Treatment resulted in resolution of symptoms and imaging findings in our cohort, and should be considered in this patient population. PMID: 33544644 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 7, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Unique Features of Posterior Ocular Involvement of Whipple's Disease in a Patient with No Gastrointestinal Symptoms.
Conclusion: Posterior ocular involvement in WD may present with a wide clinical spectrum including intraocular inflammation and unique features of sub-RPE deposits, widespread retinal hemorrhages, and optic disc edema. PMID: 33545009 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 7, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Recurrences of Scleritis after Ocular Surgery.
Authors: Vergouwen DPC, Ten Berge JC, Rothova A PMID: 33545011 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 7, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Hyperbaric Oxygen Therapy for Mumps-Associated Outer Retinitis with Frosted Branch Angiitis.
CONCLUSION: HBO therapy appears to be a feasible and safe treatment that might improve the anatomical and functional outcome in patients with mumps retinitis. PMID: 33545017 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 7, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Recurrent Uveitis Related to Ibrutinib for Treatment of Chronic Lymphocytic Leukemia.
We describe a case vision-threatening sclerouveitis as a probable adverse drug reaction to ibrutinib. Methods: Case report. Results: Ibrutinib is an inhibitor of Bruton's kinase which has shown success in the treatment of hematological malignancies such as chronic lymphocytic leukemia. Despite being generally well tolerated, recent studies have implicated ibrutinib in several adverse events affecting organs such as the heart, intestines, and the eyes. We present the case of a patient who developed severe sclerouveitis after approximately one year of ibrutinib therapy, and suggest this is a probable adverse drug reaction as...
Source: Ocular Immunology and Inflammation - February 6, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Multimodal Imaging of a Severe Case of Neonatal Acute Retinal Necrosis and Lens Vacuoles Associated with Herpes Simplex Virus Infection.
CONCLUSIONS: Clinicians should remember this rare, but devastating condition without specific prodromal symptoms. PMID: 33539717 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 6, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Avascular Necrosis of Bone in Patients with Uveitis Treated with Systemic Corticosteroids.
Conclusions: AVN is a rare but severe complication of corticosteroid therapy. Clinicians should be vigilant for symptoms of bone pain as early detection and cessation of corticosteroids can reverse incipient AVN and avoid surgery. PMID: 33539719 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 6, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Comment on "Acute Retinal Necrosis: Is the Current Valacyclovir Regimen Adequate?"
Comment on "Acute Retinal Necrosis: Is the Current Valacyclovir Regimen Adequate?" Ocul Immunol Inflamm. 2021 Jan 29;:1 Authors: von Hofsten J, Studahl M PMID: 33512259 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 31, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Corneal Graft Rejection after Yellow Fever Vaccine: A Case Report.
Conclusions: This is the first case report of corneal transplant rejection temporally associated with yellow fever vaccination. Although the yellow fever vaccine is a very safe and efficacious vaccine, the occurrence of vaccine-related rejection may be more frequent than reported. Both patients and ophthalmologists should be aware of possible vaccine-related complications which may be potentially sight-threatening. PMID: 33507830 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 30, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Retinal Vessel Diameter Changes in COVID-19 Infected Patients.
This study included 25 patients with COVID-19 (Group 1) and 25 healthy subjects (Group 2). The diameters of peripapillary temporal and nasal retinal arteries and veins were measured at baseline and at 4 months after remission. Results: The baseline diameters of the inferior temporal vein and the artery were increased in group 1 compared to controls (p = .007 and p = .041, respectively). There was also an increase in the diameters of the inferior and superior nasal veins and arteries in group 1 at baseline (p = .001, p = .019, p = .037, and p = .008, respectively). Retinal vessel diameters...
Source: Ocular Immunology and Inflammation - January 28, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Photodynamic Therapy for the Treatment of Vascularized Intraretinal Tuberculoma.
Conclusion: PDT may be a valuable second-line therapeutic approach for vascularized intraretinal granulomas. PMID: 33476223 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 23, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Tocilizumab for the Treatment of Ocular Inflammatory Disease.
Authors: Cunningham ET, Adán A, Nguyen QD, Zierhut M PMID: 33434090 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 14, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Granulicatella Adiacens as an Unusual Cause of Microbial Keratitis and Endophthalmitis: A Case Series and Literature Review.
Conclusions: These cases expand the literature on G. adiacens keratitis and endophthalmitis and corroborate the role of steroid use and prior surgery as paramount risk factors. PMID: 33426987 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 13, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Purtscher-like Retinopathy Associated with Crimean-Congo Hemorrhagic Fever: A Case Report.
CONCLUSION: Crimean-Congo hemorrhagic fever is known to cause mild ocular disease, and may also cause Purtscher-like retinopathy. It is important to aware of the ocular findings of CCHF. PMID: 33428499 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 13, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Tuberculous Scleritis and Multidrug Resistance.
Conclusion: Diagnosis of tuberculous scleritis is a challenge. Therapeutic failure must alert the clinician for drug resistance which is diagnosed early, can prevent the devastating outcomes. PMID: 33416427 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 10, 2021 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Is There a True Neuroretinitis in Idiopathic Retinal Vasculitis, Aneurysms, and Neuroretinitis (IRVAN) Syndrome ?
Conclusion : There is no clinical evidence of true neuroretinitis at any of the disease stages in patients with IRVAN syndrome. The acronym « IRVARE » (Idiopathic Retinal Vasculitis, Aneurysms, and Retinal Exudates) is proposed to better characterize this syndrome. PMID: 33331800 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 19, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Cilioretinal Artery Obstruction as a Complication of Retinitis Caused by Chikungunya Virus.
CONCLUSIONS AND IMPORTANCE: CHIKV fever has been currently associated with atypical manifestations. This indexed report describes a unique perspective on CHIKV focal retinitis, complicated by cilioretinal artery obstruction, further leading to limited visual recovery. PMID: 33297802 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 12, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Symptomatic Retinal Microangiophaty in a Patient with Coronavirus Disease 2019 (COVID-19): Single Case Report.
Conclusion: Visual field defects due to retinal microangiopathy can occur during the late phase of COVID-19. Vascular changes observed in the retina may mimic what may be happening in other, less-accessible organs. PMID: 33284032 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 9, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Analysis of Vitreous Samples by the Cellient ® Automated Cell Block System: A Six-year Review of Specimens in a Uveitis Population.
Conclusion: Our standardized protocol can be used to diagnose endophthalmitis, lymphoma, granulomatous disease, inactive and storage disease, and metastatic infiltration. Cellient analysis of vitreous specimens had a diagnostic yield of 86.3% in unsolved uveitis cases. PMID: 33269981 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 5, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Authors' Response to "Chalazia, A Late Manifestation of Primary Immunodeficiency Disorders".
Authors' Response to "Chalazia, A Late Manifestation of Primary Immunodeficiency Disorders". Ocul Immunol Inflamm. 2020 Dec 02;:1 Authors: Nieves-Moreno M, Granados M, Noval S PMID: 33264031 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 4, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

Widefield Fundus Fluorescein Angiography Features of Uveitis Associated with Juvenile Idiopathic Arthritis.
CONCLUSION: More than 70% of JIA-uveitis eyes showed some WFA-evidence of posterior segment inflammation, which changed the course of therapy for a major proportion of patients with no clinically active anterior chamber inflammation. PMID: 33264037 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 4, 2020 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research