Tubulointerstitial Nephritis and Uveitis Syndrome in Pediatric Patients
Ocul Immunol Inflamm. 2023 Nov 20:1-10. doi: 10.1080/09273948.2023.2279689. Online ahead of print.ABSTRACTTubulointerstitial nephritis and uveitis (TINU) syndrome is a disorder that was originally described in 1975. The syndrome, although diagnosed in all age ranges, is more frequently reported in pediatric patients. Diagnosis can be difficult, and its clinical spectrum is still being defined. In this article, we review the epidemiology, diagnosis, pathogenesis, clinical findings, prognosis, and treatment of both the ocular and renal disease. We comment on the current difficulties in diagnosis and study of the disease, its...
Source: Ocular Immunology and Inflammation - November 20, 2023 Category: Allergy & Immunology Authors: Timothy M Janetos Ping Hei Alfie Lee Debra A Goldstein Source Type: research
Sarcoid Uveitis in Children
Ocul Immunol Inflamm. 2023 Nov 20:1-6. doi: 10.1080/09273948.2023.2282609. Online ahead of print.ABSTRACTSarcoidosis is a multi-system granulomatous disease that often presents with uveitis. Although sarcoidosis and sarcoid uveitis typically occur in adulthood, children also may be affected. There are two distinct clinical presentations of the pediatric disease, associated with younger and older age groups, and having different causations. "Early-onset sarcoidosis", beginning at age 5 years or less, is an autosomal dominant genetic disease, caused by a mutation in the NOD2 gene. It is also known as sporadic Blau syndrome o...
Source: Ocular Immunology and Inflammation - November 20, 2023 Category: Allergy & Immunology Authors: Justine R Smith Manabu Mochizuki Source Type: research
Pediatric Pars Planitis: A Review
CONCLUSION: Timely diagnosis and adequate treatment of pediatric pars planitis and associated complications are crucial in order to improve visual outcomes.PMID:37976519 | DOI:10.1080/09273948.2023.2279683 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - November 17, 2023 Category: Allergy & Immunology Authors: Sana Khochtali Pinar Ozdal Abdulrahman F AlBloushi Wijd ène Nabi Moncef Khairallah Source Type: research
Effectiveness and Safety of Weekly Adalimumab for Non-Infectious Chronic Anterior Uveitis in Children
CONCLUSION: Weekly adalimumab in children with refractory CAU appears to be an effective and safe treatment for inflammation control and corticosteroid sparing, and an alternative before biologic switching. Controlled studies are needed.PMID:37972236 | DOI:10.1080/09273948.2023.2279682 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - November 16, 2023 Category: Allergy & Immunology Authors: Justine Huard Sorina-Dana Mihailescu Marc Muraine Solen Raymond Martine Grall Lerosey Julie Gueudry Source Type: research
Colombian Ocular Inflammatory Diseases Epidemiology Study (COIDES): Prevalence, Incidence, and Sociodemographic Characterization of Uveitis in Colombia, 2015-2020
CONCLUSIONS: Our study represents Colombia's first population-based characterization of GU, AU, and PU epidemiology. Our results highlight the importance of understanding disease patterns according to sociodemographic factors intrinsic to distinct geographic locations to design better preventive, diagnostic, and treatment approaches in the Colombian population.PMID:37972239 | DOI:10.1080/09273948.2023.2279681 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - November 16, 2023 Category: Allergy & Immunology Authors: Gabriela Florez-Esparza Carlos Cifuentes-Gonz ález William Rojas-Carabali Germ án Mejía-Salgado Juan Sebasti án Pineda-Sierra Daniella Pardo-Pizza Danna Lesley Cruz Alejandra de-la-Torre Source Type: research
