Safety and Efficacy of CLS-TA by Anatomic Location of Inflammation: Results from the Phase 3 PEACHTREE Clinical Trial
CONCLUSIONS: Irrespective of the uveitic anatomic subtype among patients treated for ME associated with NIU, a clinical benefit in participants treated with CLS-TA was demonstrated, with a comparable safety profile.PMID:38194432 | DOI:10.1080/09273948.2023.2262015 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 9, 2024 Category: Allergy & Immunology Authors: Milan Shah Thomas Albini Quan Nguyen Charles Wykoff Mark Barakat Rahul Khurana Barry Kapik Thomas A Ciulla Source Type: research
Efficacy and Safety of Switching from Adalimumab Originator to SB5, Adalimumab Biosimilar for Noninfectious Uveitis
CONCLUSION: Switching from adalimumab originator to SB5 for NIU does not result in clinically significant differences in treatment efficacy and safety.PMID:38194436 | DOI:10.1080/09273948.2023.2295544 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 9, 2024 Category: Allergy & Immunology Authors: Seok Hyeon Song Se Joon Woo Source Type: research
Bilateral Choroidal Detachments Associated with Perinuclear Anti-Neutrophil Cytoplasmic Antibodies (P-ANCA) - Associated Vasculitis
CONCLUSION: Choroidal detachment without other extraocular/intraocular inflammation can be associated with P-ANCA-associated vasculitis, a previously under-reported link. It is important to consider an inflammatory work-up for patients presenting with choroidal detachment to rule out conditions like P-ANCA-associated vasculitis.PMID:38194440 | DOI:10.1080/09273948.2023.2295535 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 9, 2024 Category: Allergy & Immunology Authors: Erkin Ötleş Kubra Serbest Ceylanoglu Hakan Demirci Source Type: research
Non-Infectious Uveitis and Pregnancy, is There an Optimal Treatment? Uveitis Course and Safety of Uveitis Treatment in Pregnancy
Ocul Immunol Inflamm. 2024 Jan 9:1-13. doi: 10.1080/09273948.2023.2296030. Online ahead of print.ABSTRACTIn pregnancy, a plethora of factors causes changes in maternal immunity. Uveitis flare-ups are more frequent in the first trimester and in undertreated patients. Management of non-infectious uveitis during pregnancy remains understudied. A bibliographic review to consolidate existing evidence was performed by a multidisciplinary group of Ophthalmologists, Gynaecologists and Rheumatologists. Our group recommends initial management with minimum-required doses of corticosteroids, preferably locally, to treat intraocular in...
Source: Ocular Immunology and Inflammation - January 9, 2024 Category: Allergy & Immunology Authors: Magdalene Yin Lin Ting Fabian Vega-Tapia Rodrigo Anguita Loreto Cuitino Rodrigo A Valenzuela Felipe Salgado Omar Valenzuela Sebastian Iba ñez Ruben Marchant Cristhian A Urzua Source Type: research
Long-Term Clinical Outcomes of the 0.18 Mg Fluocinolone Acetonide Intravitreal Implant Following Local Corticosteroid Burst in Noninfectious Uveitis
CONCLUSIONS: This treatment approach demonstrates that the 0.18 mg FAi is a useful adjuvant for the treatment of noninfectious uveitis but may not be adequate as solo therapy.PMID:38194443 | DOI:10.1080/09273948.2023.2296031 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 9, 2024 Category: Allergy & Immunology Authors: Timothy M Janetos Anjum Koreishi Debra A Goldstein Source Type: research
Optic Disk Granuloma in Eosinophilic Granulomatosis with Polyangiitis: A Case Report Illustrating the Utility of Multimodal Imaging
Ocul Immunol Inflamm. 2024 Jan 9:1-3. doi: 10.1080/09273948.2023.2295543. Online ahead of print.NO ABSTRACTPMID:38194463 | DOI:10.1080/09273948.2023.2295543 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 9, 2024 Category: Allergy & Immunology Authors: Alexandre Bourdin Alexandre Matet Helene Blin Raymond Barnhill Nathalie Cassoux Source Type: research
Incident Ocular Inflammation After COVID-19 Infection in a US Veteran Population
CONCLUSIONS: Incident ocular inflammation is associated with COVID-19 infection, but the increased risk is small, and the ocular inflammation is typically acute.PMID:38194622 | DOI:10.1080/09273948.2023.2296035 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 9, 2024 Category: Allergy & Immunology Authors: Sydney Roston Caroline L Minkus Karen R Armbrust Source Type: research
2023 Reviewer Thank You
Ocul Immunol Inflamm. 2023 Dec;31(10):2072-2073. doi: 10.1080/09273948.2023.2284621. Epub 2023 Dec 14.NO ABSTRACTPMID:38190727 | DOI:10.1080/09273948.2023.2284621 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 8, 2024 Category: Allergy & Immunology Source Type: research
Long-Term Visual Outcome of Patients with Blau Syndrome
CONCLUSION: Uveitis associated with Blau syndrome commonly leads to severe, chronic panuveitis, requiring long-term systemic immunosuppression. Early diagnosis and timely initiation of biologics may prevent significant visual impairment.PMID:38180755 | DOI:10.1080/09273948.2023.2293922 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - January 5, 2024 Category: Allergy & Immunology Authors: Elke O Kreps Dalila Al Julandani Catherine M Guly Juan I Arostegui Andrew D Dick Athimalaipet V Ramanan Source Type: research
Retinal Vasculitis in a Patient with Rhupus
Ocul Immunol Inflamm. 2024 Jan 4:1-3. doi: 10.1080/09273948.2023.2295533. Online ahead of print.ABSTRACTThis case report describes a case of retinal vasculitis in a patient with Rhupus, which has not been reported earlier in the literature. A 39-year-old female patient with a history of Rhupus presented with sudden vision loss in her left eye. The patient was treated earlier, for her polyarthritis, with oral corticosteroids, hydroxychloroquine, and oral methotrexate, which were discontinued after 1 year of treatment. At presentation, fundus examination of the left eye revealed mild vitritis, perivenous sheathing, and hemor...
Source: Ocular Immunology and Inflammation - January 4, 2024 Category: Allergy & Immunology Authors: Harshali Kamat Ashad Sivaraman Mithun C B Parthopratim Dutta Majumder Source Type: research
Uveitis Following Intravitreal Injections of Faricimab: A Case Report
CONCLUSIONS: These cases prompt further investigation into the potential risk of uveitis associated with faricimab and underscore the importance of continued monitoring and research to elucidate its real-world safety profile.PMID:38133943 | DOI:10.1080/09273948.2023.2293925 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 22, 2023 Category: Allergy & Immunology Authors: Filomena Palmieri Saad Younis Aseel Bedan Hamoud Lorenzo Fabozzi Source Type: research
Colombian Ocular Inflammatory Diseases Epidemiology Study (COIDES): Optic Neuritis Incidence Between 2015-2020
CONCLUSIONS: The incidence of ON in Colombia is lower compared to countries in the northern hemisphere, with women under 50 years being predominantly affected. The onset of the COVID-19 pandemic corresponded with a reduction in identifying new ON cases. This underscores governments' need to implement effective diagnostic strategies in the future.PMID:38133944 | DOI:10.1080/09273948.2023.2295538 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 22, 2023 Category: Allergy & Immunology Authors: Camilo Andr és Rodríguez-Rodríguez Carlos Cifuentes-Gonz ález Germ án Mejía-Salgado Juan Manuel Garz ón-Dangond Angie Vanessa Verbel-Yaneth Sofia Machado-Galindo Danna Lesley Cruz-Reyes Alejandra de-la-Torre Source Type: research
