Why do Doctors Miss the Diagnosis of Leptospiral Uveitis? Emergence of New Serovars and Challenges in Diagnosis
CONCLUSIONS: The data suggest a declining sensitivity of MAT and ELISA, possibly due to the emergence of new serovars. Customizing the panel based on local isolates could enhance the performance of MAT. Critical need is the addition of advanced molecular techniques to improve the diagnosis.PMID:38127787 | DOI:10.1080/09273948.2023.2291477 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 21, 2023 Category: Allergy & Immunology Authors: S R Rathinam Rajesh Vedhanayagi Manoj Radhika M S Balamurugan K Balagiri C Gowri Priya G Jeya Kohila Source Type: research
Treatment Adherence Effect on the Visual Acuity of Beh çet's Uveitis Patients
CONCLUSION: Poor treatment adherence in BU patients has a negative effect on final visual acuity outcomes. Moreover, BU patients experience lower QoL and higher rates of depression and anxiety compared to the healthy control group. These findings highlight the importance of addressing treatment adherence and psychological well-being in the management of BU.PMID:38127797 | DOI:10.1080/09273948.2023.2288905 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 21, 2023 Category: Allergy & Immunology Authors: Murat Oklar Nil üfer Zorlutuna Kaymak Burak Tanyildiz Mehmet Engin Tezcan Şaban Şimşek Source Type: research
Macrophage Migration Inhibitory Factor (MIF) is a Key Player in Dry Eye Disease
CONCLUSION: MIF is a central positive mediator of the inflammatory process in experimental DED, thus, targeting MIF could be used as a novel therapy in ocular surface inflammatory pathologies.PMID:38127798 | DOI:10.1080/09273948.2023.2290624 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 21, 2023 Category: Allergy & Immunology Authors: Luis A Rivera Pablo E Hern ández Danielle T Vannan Jos é L Reyes Tonathiu Rodr íguez Ángel Sánchez-Barrera Marisol I Gonz ález Jos é Bustos Oscar A Ramos Imelda Ju árez Miriam Rodriguez-Sosa Alicia V ázquez Source Type: research
Bilateral Scleritis with Heterogeneous Etiologies: A Diagnostic Dilemma
CONCLUSION: Retinal detachment may be associated with scleritis, and ANCA testing may not detect GPA in its early stages. Once infection has been excluded, clinicians should not be afraid to use high-dose immunosuppression instead of surgery to treat retinal detachment associated with scleritis.PMID:38127820 | DOI:10.1080/09273948.2023.2288212 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 21, 2023 Category: Allergy & Immunology Authors: Parthopratim Dutta Majumder Mamta Agarwal Anitha Manoharan Appakkudal R Anand Source Type: research
Leptospiral Uveitis: Case Series and Review of Literature
CONCLUSION: Leptospiral uveitis is an under-reported entity. It may present as anterior uveitis or panuveitis. It must be included in the differential diagnosis of non-granulomatous uveitis. The visual prognosis is usually favorable even in severe cases.PMID:38128077 | DOI:10.1080/09273948.2023.2296037 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 21, 2023 Category: Allergy & Immunology Authors: Abhilasha Baharani Raja Rami Reddy P Source Type: research
Intracameral Fibrinous Reaction During Descemet's Membrane Endothelial Keratoplasty
CONCLUSION: Fibrinous reaction is a rare intraoperative complication of DMEK that interferes with graft unfolding and results in poor outcomes. Anticoagulant use appears to be a risk factor and may be compounded by surgical trauma to vascular tissues and prolonged surgical maneuvers.PMID:38109198 | DOI:10.1080/09273948.2023.2287057 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 18, 2023 Category: Allergy & Immunology Authors: Cristina Bostan Mika ël Bernier Tanguy Boutin Elise Slim Mich èle Mabon Isabelle Brunette Johanna Choremis Julia C Talajic Source Type: research
Molecular Analysis of Liquid Vitreous Biopsy Reveals Occult Lymphoma Following Cytology-Negative Biopsies of the Brain and Vitreous
CONCLUSION: This case illustrates the unique contribution of liquid biopsy neuropathology-oriented molecular testing in a challenging case with high clinical suspicion of PCNSL in which gold-standard diagnostic testing failed to yield a diagnosis.PMID:38109211 | DOI:10.1080/09273948.2023.2287061 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 18, 2023 Category: Allergy & Immunology Authors: Daniel A Balikov Kyle Conway Noah A Brown Sandra Camelo-Piragua Rajesh C Rao Source Type: research
Intracameral Fibrinous Reaction During Descemet's Membrane Endothelial Keratoplasty
CONCLUSION: Fibrinous reaction is a rare intraoperative complication of DMEK that interferes with graft unfolding and results in poor outcomes. Anticoagulant use appears to be a risk factor and may be compounded by surgical trauma to vascular tissues and prolonged surgical maneuvers.PMID:38109198 | DOI:10.1080/09273948.2023.2287057 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 18, 2023 Category: Allergy & Immunology Authors: Cristina Bostan Mika ël Bernier Tanguy Boutin Elise Slim Mich èle Mabon Isabelle Brunette Johanna Choremis Julia C Talajic Source Type: research
Molecular Analysis of Liquid Vitreous Biopsy Reveals Occult Lymphoma Following Cytology-Negative Biopsies of the Brain and Vitreous
CONCLUSION: This case illustrates the unique contribution of liquid biopsy neuropathology-oriented molecular testing in a challenging case with high clinical suspicion of PCNSL in which gold-standard diagnostic testing failed to yield a diagnosis.PMID:38109211 | DOI:10.1080/09273948.2023.2287061 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 18, 2023 Category: Allergy & Immunology Authors: Daniel A Balikov Kyle Conway Noah A Brown Sandra Camelo-Piragua Rajesh C Rao Source Type: research
Intracameral Fibrinous Reaction During Descemet's Membrane Endothelial Keratoplasty
CONCLUSION: Fibrinous reaction is a rare intraoperative complication of DMEK that interferes with graft unfolding and results in poor outcomes. Anticoagulant use appears to be a risk factor and may be compounded by surgical trauma to vascular tissues and prolonged surgical maneuvers.PMID:38109198 | DOI:10.1080/09273948.2023.2287057 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 18, 2023 Category: Allergy & Immunology Authors: Cristina Bostan Mika ël Bernier Tanguy Boutin Elise Slim Mich èle Mabon Isabelle Brunette Johanna Choremis Julia C Talajic Source Type: research
Molecular Analysis of Liquid Vitreous Biopsy Reveals Occult Lymphoma Following Cytology-Negative Biopsies of the Brain and Vitreous
CONCLUSION: This case illustrates the unique contribution of liquid biopsy neuropathology-oriented molecular testing in a challenging case with high clinical suspicion of PCNSL in which gold-standard diagnostic testing failed to yield a diagnosis.PMID:38109211 | DOI:10.1080/09273948.2023.2287061 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 18, 2023 Category: Allergy & Immunology Authors: Daniel A Balikov Kyle Conway Noah A Brown Sandra Camelo-Piragua Rajesh C Rao Source Type: research
Roles of Sphingosine Kinase and Sphingosine-1-Phosphate Receptor 2 in Endotoxin-Induced Acute Retinal Inflammation
CONCLUSION: SphK1/S1P/S1PR2 signaling was upregulated in EIU and S1PR2 inhibition suppressed inflammatory response. Targeting this signaling pathway has potential for treating retinal inflammatory diseases.PMID:38100527 | DOI:10.1080/09273948.2023.2273963 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 15, 2023 Category: Allergy & Immunology Authors: Tazbir Ahmed Takafumi Suzuki Ryo Terao Reiko Yamagishi Ryosuke Fujino Kunihiro Azuma Hirotsugu Soga Takashi Ueta Megumi Honjo Sumiko Watanabe Kazuaki Yoshioka Yoh Takuwa Makoto Aihara Source Type: research
Pediatric Posterior Infectious Uveitis
CONCLUSION: Infectious posterior uveitis is a challenging subject and should be considered in the differential diagnosis of any posterior uveitis in children. Infectious uveitis must be excluded before initiating immunosuppressive therapy.PMID:38096404 | DOI:10.1080/09273948.2023.2284990 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 14, 2023 Category: Allergy & Immunology Authors: Andr é Luiz Land Curi Alejandra de-la-Torre Ariel Schlaen Papdmamalini Mahendradas Jyortimay Biswas Source Type: research
