Cytomegalovirus Corneal Endotheliitis: A Comprehensive Review
Ocul Immunol Inflamm. 2024 Feb 28:1-10. doi: 10.1080/09273948.2024.2320704. Online ahead of print.ABSTRACTCytomegalovirus (CMV) anterior uveitis and corneal endotheliitis are the most common ocular diseases caused by CMV infections in immunocompetent patients. The incidence of CMV corneal endotheliitis is relatively high in middle-aged men. CMV corneal endotheliitis presents with mild anterior chamber inflammation, corneal edema, keratic precipitates, and elevated intraocular pressure. It resembles Posner-Schlossman syndrome and Fuchs uveitis because of the elevated intraocular pressure. Without proper diagnosis and treatm...
Source: Ocular Immunology and Inflammation - February 28, 2024 Category: Allergy & Immunology Authors: Woong-Sun Yoo Lee-Ha Kwon Youngsub Eom Zheng Xian Thng Christopher Or Quan Dong Nguyen Seong-Jae Kim Source Type: research

Uveitis Onset and Flare-Up: Does the Time of Year Matter?
CONCLUSION: While variation by month, calendar season, or temperature is not present for all uveitis patients, a subset of patients with comorbid autoimmune conditions, specifically HLA-B27 positive, experience temperature variations with increasing incidence of flare-ups in transitional months in Connecticut.PMID:38411923 | DOI:10.1080/09273948.2024.2320701 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 27, 2024 Category: Allergy & Immunology Authors: Leena Surapaneni Paige Orlofsky Ninani Kombo Source Type: research

Automated Machine Learning versus Expert-Designed Models in Ocular Toxoplasmosis: Detection and Lesion Localization Using Fundus Images
CONCLUSION: AutoML models created by ophthalmologists without coding experience were comparable or better than expert-designed bespoke models trained on the same dataset. By creatively using AutoML to identify OT lesions on fundus images, our approach brings the whole spectrum of DL model design into the hands of clinicians.PMID:38411944 | DOI:10.1080/09273948.2024.2319281 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 27, 2024 Category: Allergy & Immunology Authors: Daniel Milad Fares Antaki Allison Bernstein Samir Touma Renaud Duval Source Type: research

VKH with APECED in a Two-Year-Old Child: A Rare Concomitant Diagnosis in an Unprecedented Age
CONCLUSION: APECED is a rare endocrine disorder and has been reported to be associated with VKH twice. Likewise, VKH is commonly present in much older patients; this is the first time ever to be diagnosed in a two-year-old child.PMID:38412247 | DOI:10.1080/09273948.2023.2208212 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 27, 2024 Category: Allergy & Immunology Authors: Lameece Moustafa Hassan Mona M Hassan Hend Abou Shady Dina Khedr Source Type: research

Drug Retention Time of Immunosuppressive Therapy in Behcet's Uveitis
CONCLUSION: Adalimumab's drug retention time was found to be similar to and possibly better than cDMARDs in patients with BU, who often suffer from vision-threatening disease at first presentation.PMID:38412375 | DOI:10.1080/09273948.2024.2315205 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 27, 2024 Category: Allergy & Immunology Authors: Donald Tran Sophie Rogers Lyndell L Lim Source Type: research

Herpes-Zoster-Related Choroidopathy - A Report of Two Cases
CONCLUSION: This report demonstrates a very rare, late finding of choroidal involvement in two HZO cases.PMID:38412396 | DOI:10.1080/09273948.2024.2320709 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 27, 2024 Category: Allergy & Immunology Authors: Melis Kabaalioglu Guner Eric Weldy Michelle M Abou-Jaoude Source Type: research

Uveitis Onset and Flare-Up: Does the Time of Year Matter?
CONCLUSION: While variation by month, calendar season, or temperature is not present for all uveitis patients, a subset of patients with comorbid autoimmune conditions, specifically HLA-B27 positive, experience temperature variations with increasing incidence of flare-ups in transitional months in Connecticut.PMID:38411923 | DOI:10.1080/09273948.2024.2320701 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 27, 2024 Category: Allergy & Immunology Authors: Leena Surapaneni Paige Orlofsky Ninani Kombo Source Type: research

Automated Machine Learning versus Expert-Designed Models in Ocular Toxoplasmosis: Detection and Lesion Localization Using Fundus Images
CONCLUSION: AutoML models created by ophthalmologists without coding experience were comparable or better than expert-designed bespoke models trained on the same dataset. By creatively using AutoML to identify OT lesions on fundus images, our approach brings the whole spectrum of DL model design into the hands of clinicians.PMID:38411944 | DOI:10.1080/09273948.2024.2319281 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 27, 2024 Category: Allergy & Immunology Authors: Daniel Milad Fares Antaki Allison Bernstein Samir Touma Renaud Duval Source Type: research

Suspected Retinal Toxicity After Multiple Intravitreal Ganciclovir Injections in a Patient of CMV Retinitis
CONCLUSION AND IMPORTANCE: We present a case of progressive diffuse RPE atrophy as a result of toxicity of intravitreal ganciclovir injections. It is important to be aware of this rare potential toxicity of intravitreal Ganciclovir.PMID:38407965 | DOI:10.1080/09273948.2024.2316754 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 26, 2024 Category: Allergy & Immunology Authors: Rohan Kapoor SriniVas Sadda Mudit Tyagi Source Type: research

Investigating the Accuracy and Completeness of an Artificial Intelligence Large Language Model About Uveitis: An Evaluation of ChatGPT
CONCLUSION: ChatGPT can provide relatively high accuracy responses for various questions related to uveitis; however, the answers it provides are incomplete, with some inaccuracies. Its utility in providing medical information requires further validation and development prior to serving as a source of uveitis information for patients.PMID:38394625 | DOI:10.1080/09273948.2024.2317417 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 23, 2024 Category: Allergy & Immunology Authors: Rayna F Marshall Krishna Mallem Hannah Xu Jennifer Thorne Bryn Burkholder Benjamin Chaon Paulina Liberman Meghan Berkenstock Source Type: research

Surgical Outcomes in Uveitic Glaucoma: Long-Term Evaluation of Trabeculectomy, Non-Penetrating Deep Sclerectomy, Ex-PRESS Shunt and Ahmed Glaucoma Valve. A 3-Year Follow-Up Study
CONCLUSION: Various filtering surgeries are safe and effective procedures for lowering IOP and reducing the requirement of topical antihypertensives in UG at 36 months. However, one-third of the patients will require another IOP-lowering procedure.PMID:38381450 | DOI:10.1080/09273948.2024.2315194 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 21, 2024 Category: Allergy & Immunology Authors: David Arag ón-Roca David Oliver-Gutierrez Sandra Banderas Garc ía Jaume Rigo Antonio Dou Marta Castany Source Type: research