Uveitis and Dry Eye Disease in Children: A Cross-Sectional Comparative Study
CONCLUSIONS: Our findings demonstrate a significantly higher prevalence of DED in children with uveitis compared to their healthy counterparts. Furthermore, our analysis indicates that the risk of DED in pediatric patients with uveitis is threefold higher than in healthy children. Therefore, it is crucial for clinicians to vigilantly monitor the development of DED in pediatric patients with uveitis and consider the implementation of preventive treatments.PMID:38376892 | DOI:10.1080/09273948.2024.2317416 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 20, 2024 Category: Allergy & Immunology Authors: William Rojas-Carabali Germ án Mejía-Salgado Valeria Villabona-Mart ínez Dom énico Barraquer-López Carlos Cifuentes-Gonz ález Guillermo Marroqu ín Pilar Del Rosario Guarnizo Zuccardi Alejandra de-la-Torre Source Type: research
Periodontal Ligament Stem Cell-Derived Exosomes Regulate Muc5ac Expression in Rat Conjunctival Goblet Cells via Regulating Macrophages Toward an Anti-Inflammatory Phenotype
CONCLUSION: PDLSC-Exos could protect CGCs against M1 macrophage-mediated inflammation, and the protective effects of PDLSC-Exos are partly attributable to their effects on M1 macrophages.PMID:38363299 | DOI:10.1080/09273948.2024.2311981 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 16, 2024 Category: Allergy & Immunology Authors: Yiqian Ren Yani Wang Na An Xianghua Xiao Shiyin Pan Bei Wang Xianning Liu Yao Wang Source Type: research
Evaluation of Dry Eye Severity and Ocular Surface Inflammation in Patients with Autoimmune Rheumatic Diseases
CONCLUSIONS: Variable degrees of dry eye and immune-mediated ocular surface inflammation persist in different ARD patients. In addition to a well-known association between dry eye and pSS, dry eye is also commonly observed in SLE and RA patients. Therefore, there is a definite need for regular ophthalmologic evaluations and topical medications in all patients with ARDs.PMID:38363334 | DOI:10.1080/09273948.2024.2315196 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 16, 2024 Category: Allergy & Immunology Authors: Yingyi Liu Mengbo Wu Yuerong Ren Jianing Feng Wen Shi Huanmin Kang Jing Tian Yan He Source Type: research
Familial Mediterranean Fever-Associated Retinal Vasculitis: A Rare Manifestation Successfully Managed with IL-1 Pathway Inhibitors
CONCLUSION: This case underscores the rarity of retinal vasculitis in FMF, particularly involving arteries, and highlights the correlation between specific gene mutations (M680I, M694V) and disease severity. The successful management with IL-1 pathway inhibitors suggests a potential therapeutic approach. Increased clinical awareness, further research, and reporting are crucial for optimizing the understanding and treatment of FMF-related ocular manifestations.PMID:38364019 | DOI:10.1080/09273948.2024.2317978 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 16, 2024 Category: Allergy & Immunology Authors: Natalia Anglada-Masferrer Yann Bertolani Liliana Gutuleac J úlia Angrill Valls Laura Distefano Eric Kirkegaard-Biosca Source Type: research
Periodontal Ligament Stem Cell-Derived Exosomes Regulate Muc5ac Expression in Rat Conjunctival Goblet Cells via Regulating Macrophages Toward an Anti-Inflammatory Phenotype
CONCLUSION: PDLSC-Exos could protect CGCs against M1 macrophage-mediated inflammation, and the protective effects of PDLSC-Exos are partly attributable to their effects on M1 macrophages.PMID:38363299 | DOI:10.1080/09273948.2024.2311981 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 16, 2024 Category: Allergy & Immunology Authors: Yiqian Ren Yani Wang Na An Xianghua Xiao Shiyin Pan Bei Wang Xianning Liu Yao Wang Source Type: research
Evaluation of Dry Eye Severity and Ocular Surface Inflammation in Patients with Autoimmune Rheumatic Diseases
CONCLUSIONS: Variable degrees of dry eye and immune-mediated ocular surface inflammation persist in different ARD patients. In addition to a well-known association between dry eye and pSS, dry eye is also commonly observed in SLE and RA patients. Therefore, there is a definite need for regular ophthalmologic evaluations and topical medications in all patients with ARDs.PMID:38363334 | DOI:10.1080/09273948.2024.2315196 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 16, 2024 Category: Allergy & Immunology Authors: Yingyi Liu Mengbo Wu Yuerong Ren Jianing Feng Wen Shi Huanmin Kang Jing Tian Yan He Source Type: research
Familial Mediterranean Fever-Associated Retinal Vasculitis: A Rare Manifestation Successfully Managed with IL-1 Pathway Inhibitors
CONCLUSION: This case underscores the rarity of retinal vasculitis in FMF, particularly involving arteries, and highlights the correlation between specific gene mutations (M680I, M694V) and disease severity. The successful management with IL-1 pathway inhibitors suggests a potential therapeutic approach. Increased clinical awareness, further research, and reporting are crucial for optimizing the understanding and treatment of FMF-related ocular manifestations.PMID:38364019 | DOI:10.1080/09273948.2024.2317978 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 16, 2024 Category: Allergy & Immunology Authors: Natalia Anglada-Masferrer Yann Bertolani Liliana Gutuleac J úlia Angrill Valls Laura Distefano Eric Kirkegaard-Biosca Source Type: research
Periodontal Ligament Stem Cell-Derived Exosomes Regulate Muc5ac Expression in Rat Conjunctival Goblet Cells via Regulating Macrophages Toward an Anti-Inflammatory Phenotype
CONCLUSION: PDLSC-Exos could protect CGCs against M1 macrophage-mediated inflammation, and the protective effects of PDLSC-Exos are partly attributable to their effects on M1 macrophages.PMID:38363299 | DOI:10.1080/09273948.2024.2311981 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 16, 2024 Category: Allergy & Immunology Authors: Yiqian Ren Yani Wang Na An Xianghua Xiao Shiyin Pan Bei Wang Xianning Liu Yao Wang Source Type: research
Evaluation of Dry Eye Severity and Ocular Surface Inflammation in Patients with Autoimmune Rheumatic Diseases
CONCLUSIONS: Variable degrees of dry eye and immune-mediated ocular surface inflammation persist in different ARD patients. In addition to a well-known association between dry eye and pSS, dry eye is also commonly observed in SLE and RA patients. Therefore, there is a definite need for regular ophthalmologic evaluations and topical medications in all patients with ARDs.PMID:38363334 | DOI:10.1080/09273948.2024.2315196 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 16, 2024 Category: Allergy & Immunology Authors: Yingyi Liu Mengbo Wu Yuerong Ren Jianing Feng Wen Shi Huanmin Kang Jing Tian Yan He Source Type: research
Familial Mediterranean Fever-Associated Retinal Vasculitis: A Rare Manifestation Successfully Managed with IL-1 Pathway Inhibitors
CONCLUSION: This case underscores the rarity of retinal vasculitis in FMF, particularly involving arteries, and highlights the correlation between specific gene mutations (M680I, M694V) and disease severity. The successful management with IL-1 pathway inhibitors suggests a potential therapeutic approach. Increased clinical awareness, further research, and reporting are crucial for optimizing the understanding and treatment of FMF-related ocular manifestations.PMID:38364019 | DOI:10.1080/09273948.2024.2317978 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 16, 2024 Category: Allergy & Immunology Authors: Natalia Anglada-Masferrer Yann Bertolani Liliana Gutuleac J úlia Angrill Valls Laura Distefano Eric Kirkegaard-Biosca Source Type: research
Periodontal Ligament Stem Cell-Derived Exosomes Regulate Muc5ac Expression in Rat Conjunctival Goblet Cells via Regulating Macrophages Toward an Anti-Inflammatory Phenotype
CONCLUSION: PDLSC-Exos could protect CGCs against M1 macrophage-mediated inflammation, and the protective effects of PDLSC-Exos are partly attributable to their effects on M1 macrophages.PMID:38363299 | DOI:10.1080/09273948.2024.2311981 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 16, 2024 Category: Allergy & Immunology Authors: Yiqian Ren Yani Wang Na An Xianghua Xiao Shiyin Pan Bei Wang Xianning Liu Yao Wang Source Type: research
Evaluation of Dry Eye Severity and Ocular Surface Inflammation in Patients with Autoimmune Rheumatic Diseases
CONCLUSIONS: Variable degrees of dry eye and immune-mediated ocular surface inflammation persist in different ARD patients. In addition to a well-known association between dry eye and pSS, dry eye is also commonly observed in SLE and RA patients. Therefore, there is a definite need for regular ophthalmologic evaluations and topical medications in all patients with ARDs.PMID:38363334 | DOI:10.1080/09273948.2024.2315196 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 16, 2024 Category: Allergy & Immunology Authors: Yingyi Liu Mengbo Wu Yuerong Ren Jianing Feng Wen Shi Huanmin Kang Jing Tian Yan He Source Type: research
Familial Mediterranean Fever-Associated Retinal Vasculitis: A Rare Manifestation Successfully Managed with IL-1 Pathway Inhibitors
CONCLUSION: This case underscores the rarity of retinal vasculitis in FMF, particularly involving arteries, and highlights the correlation between specific gene mutations (M680I, M694V) and disease severity. The successful management with IL-1 pathway inhibitors suggests a potential therapeutic approach. Increased clinical awareness, further research, and reporting are crucial for optimizing the understanding and treatment of FMF-related ocular manifestations.PMID:38364019 | DOI:10.1080/09273948.2024.2317978 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 16, 2024 Category: Allergy & Immunology Authors: Natalia Anglada-Masferrer Yann Bertolani Liliana Gutuleac J úlia Angrill Valls Laura Distefano Eric Kirkegaard-Biosca Source Type: research
Real-World Experience in the Use of Immunosuppression for the Management of Inflammatory Eye Disease
CONCLUSION: Progressive conditions, such as cicatrising conjunctivitis may require lifelong immunosuppression, but patients with NIU and Scleritis and those on CTSS, immunosuppression withdrawal should be considered if they remain in remission for 2 years. Any patient stopping a medication should be contacted immediately for counselling. These data will better inform patients, encourage adherence and aide formal guideline development.PMID:38349962 | DOI:10.1080/09273948.2024.2311743 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 13, 2024 Category: Allergy & Immunology Authors: Matthew Azzopardi Yu Jeat Chong Sreekanth Sreekantam Robert J Barry Natraj Poonit Saaeha Rauz Philip I Murray Source Type: research
Acute Unilateral Hypertensive Uveitis in Leptospirosis: A Case Report
CONCLUSION: Leptospirosis should be considered as a differential in the diagnosis of acute hypertensive uveitis.PMID:38350005 | DOI:10.1080/09273948.2024.2312237 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 13, 2024 Category: Allergy & Immunology Authors: Yogish Subraya Kamath Alisha Rizvi Shashidhar Vishwanath Ravikumar T N Raghavendra Rao Ram Bhat Source Type: research
