Total polyphenol, total phenolic and antioxidant activities of different peanut (Arachis hypogaea L.) market types by Different Techniques Combined with Chemometrics (PCA and HCA)
In this study, it is aimed to determine the antioxidant activity, total polyphenol and total flavonoid content of peanuts from four different market types, for the first time, and group them with principal component analysis (PCA) and hierarchical cluster analysis (HCA). The total polyphenol content changed 1.556 to 2.899 mg GAE/g.The lowest value have seen at Spanish merket type to determine the antioxidant activities of peanut samples were maked FRAP and DPPH assay, the lowest FRAP value (8.136 µmol FeSO47H2O/g sample) was seen at Valencia market type, the highest (14.004 µmol FeSO47H2O/g sample) was seen at Virginia m...
Source: Chemistry and Biodiversity - February 21, 2024 Category: Biochemistry Authors: Bet ül Gıdık Zehra Can Fadul Önemli Source Type: research

Genes, Vol. 15, Pages 265: Genome-Wide Characterization of the Phenylalanine Ammonia-Lyase Gene Family and Their Potential Roles in Response to Aspergillus flavus L. Infection in Cultivated Peanut (Arachis hypogaea L.)
ng Suoyi Han Xinyou Zhang Phenylalanine ammonia-lyase (PAL) is an essential enzyme in the phenylpropanoid pathway, in which numerous aromatic intermediate metabolites play significant roles in plant growth, adaptation, and disease resistance. Cultivated peanuts are highly susceptible to Aspergillus flavus L. infection. Although PAL genes have been characterized in various major crops, no systematic studies have been conducted in cultivated peanuts, especially in response to A. flavus infection. In the present study, a systematic genome-wide analysis was conducted to identify PAL genes in the Arachis hypogaea L. gen...
Source: Genes - February 21, 2024 Category: Genetics & Stem Cells Authors: Pengpei Chai Mengjie Cui Qi Zhao Linjie Chen Tengda Guo Jingkun Guo Chendi Wu Pei Du Hua Liu Jing Xu Zheng Zheng Bingyan Huang Wenzhao Dong Suoyi Han Xinyou Zhang Tags: Article Source Type: research

Genome-wide analysis of the peanut CaM/CML gene family reveals that the AhCML69 gene is associated with resistance to Ralstonia solanacearum
Calmodulins (CaMs)/CaM-like proteins (CMLs) are crucial Ca2+-binding sensors that can decode and transduce Ca2+ signals during plant development and in response to various stimuli. The CaM/CML gene family has bee... (Source: BMC Genomics)
Source: BMC Genomics - February 21, 2024 Category: Genetics & Stem Cells Authors: Dong Yang, Ting Chen, Yushuang Wu, Huiquan Tang, Junyi Yu, Xiaoqiu Dai, Yixiong Zheng, Xiaorong Wan, Yong Yang and Xiaodan Tan Tags: Research Source Type: research

Meta-transcriptomic identification of groundnut RNA viruses in western Kenya and the novel detection of groundnut as a host for Cauliflower mosaic virus
CONCLUSION: Our findings demonstrate the power of Next Generation Sequencing in the discovery and identification of novel viruses in groundnuts. The detection of the new viruses indicates the complexity of virus diseases in groundnuts and would require more focus in future studies to establish the effect of the viruses as sole or mixed infections on the crop. The detection of PeMoV with potential origin from Malawi indicates the importance of seed certification and cross-boundary seed health testing.PMID:38367474 | DOI:10.1016/j.virol.2024.110011 (Source: Virology)
Source: Virology - February 17, 2024 Category: Virology Authors: Dennis Obonyo George Ouma Rachel Ikawa Damaris A Odeny Source Type: research

Early solid introduction to prevent IgE-mediated food allergy should continue unabated while we learn more about FPIES prevalence
Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated allergy that typically presents in infancy with introduction of infant formula or solid foods. While previously thought to be rare, recent studies have reported a notable increase in prevalence, particularly among peanut and egg (Table 1). FPIES to peanut has historically been uncommon. Interestingly, several case series have described increased incidence of peanut FPIES in recent years and cited the 2015 Learning Early about Peanut Allergy (LEAP) study as a potential driving factor. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 16, 2024 Category: Allergy & Immunology Authors: Linlei Ye, Stephanie C. Erdle, Elissa M. Abrams, Edmond S. Chan Tags: Perspective Source Type: research

Early solid introduction to prevent IgE –mediated food allergy should continue unabated while we learn more about food protein–induced enterocolitis syndrome prevalence
Food protein –induced enterocolitis syndrome (FPIES) is a non–IgE-mediated allergy that typically presents in infancy with the introduction of infant formula or solid foods. Whereas previously thought to be rare, recent studies have reported a notable increase in prevalence, particularly among peanut and egg (Table 1). Moreover, FPIES to peanut has historically been uncommon. Interestingly, several case series have described the increased incidence of peanut FPIES in recent years and cited the 2015 Learning Early about Peanut Allergy study as a potential driving factor. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - February 16, 2024 Category: Allergy & Immunology Authors: Linlei Ye, Stephanie C. Erdle, Elissa M. Abrams, Edmond S. Chan Tags: Perspective Source Type: research

Defining the cross-reactivity between peanut allergens Ara h 2 and Ara h 6 using monoclonal antibodies
Clin Exp Immunol. 2024 Feb 12:uxae005. doi: 10.1093/cei/uxae005. Online ahead of print.ABSTRACTIn peanut allergy, Arachis hypogaea 2 (Ara h 2) and Arachis hypogaea 6 (Ara h 6) are two clinically relevant peanut allergens with known structural and sequence homology and demonstrated cross-reactivity. We have previously utilized X-ray crystallography and epitope binning to define the epitopes on Ara h 2. We aimed to quantitatively characterize the cross-reactivity between Ara h 2 and Ara h 6 on a molecular level using human monoclonal antibodies (mAbs) and structural characterization of allergenic epitopes. We utilized mAbs c...
Source: Clinical and Developmental Immunology - February 12, 2024 Category: Allergy & Immunology Authors: Orlee Marini-Rapoport Monica L Fern ández-Quintero Tarun Keswani Guangning Zong Jane Shim Lars C Pedersen Geoffrey A Mueller Sarita U Patil Source Type: research

Transcriptional study of genes involved in the passage from teliospore to hyphae stage in the fungus Thecaphora frezii, the causal agent of peanut smut
Rev Argent Microbiol. 2024 Feb 8:S0325-7541(24)00003-8. doi: 10.1016/j.ram.2023.10.002. Online ahead of print.ABSTRACTPeanuts (Arachis hypogaea L.) are among the most important leguminous crops in Argentina. During the growing season, they are frequently attacked by fungal diseases, including Thecaphora frezii. The spores of T. frezii are structures that confer resistance to this phytopathogen. The transition from teliospore to hypha is a characteristic process of some fungi, which is essential for completing their life cycle. Using the transcriptomes of teliospores and hyphae of T. frezii, we aimed to identify genes that ...
Source: Revista Argentina de Microbiologia - February 9, 2024 Category: Microbiology Authors: Mar ía S Díaz N éstor W Soria Ana C Figueroa Pablo Yang Esteban H Badariotti Valeria R Alasino Pablo V élez Dante M Beltramo Source Type: research

Safety and efficacy of epicutaneous immunotherapy with DBV712 (peanut patch) in peanut allergy
Expert Rev Clin Immunol. 2024 Feb 14:1-11. doi: 10.1080/1744666X.2024.2315221. Online ahead of print.ABSTRACTINTRODUCTION: DBV712 250 µg (also referred to as Viaskin Peanut or peanut patch; Viaskin is a trademark of DBV Technologies) is an innovative approach to epicutaneous immunotherapy (EPIT). The patch-based technology system facilitates peanut protein (allergen) absorption into the intact non-vascularized epidermis to promote desensitization to peanut while limiting systemic allergen exposure.AREAS COVERED: Efficacy and safety in children have been evaluated in four completed phase 3 studies. Overall, the results fro...
Source: Expert Review of Clinical Immunology - February 7, 2024 Category: Allergy & Immunology Authors: Christophe Dupont A Wesley Burks David M Fleischer Katharine J Bee Sarita Chainani Hugh A Sampson Source Type: research

Sustained silencing peanut allergy by xanthopurpurin is associated with suppression of peripheral and bone marrow IgE-producing B cell
ConclusionsXPP successfully protected peanut-allergic mice against peanut anaphylaxis by suppressing IgE production. XPP suppresses murine IgE-producing B cell numbers and inhibits IgE production and associated genes in human plasma cells. XPP may be a potential therapy for IgE-mediated food allergy. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - February 6, 2024 Category: Allergy & Immunology Source Type: research

In situ formation of natural deep eutectic solvent on membrane after fat hydrolysis for lindane isomers determination in peanut paste
Talanta. 2024 Jan 30;271:125737. doi: 10.1016/j.talanta.2024.125737. Online ahead of print.ABSTRACTIn this work a sample pretreatment approach assumed liquid-liquid microextraction based on the in situ formation of a hydrophobic natural deep eutectic solvent on a hydrophobic membrane impregnated with natural terpenoid was developed. The procedure included alkaline hydrolysis of a food sample containing fat to form fatty acids, which acted as precursors for the in situ formation of the deep eutectic solvent with natural terpenoid. Two processes were observed on the membrane surface: in situ formation of the hydrophobic deep...
Source: Talanta - February 3, 2024 Category: Chemistry Authors: Firuza Krekhova Daria Meshcheva Andrey Shishov Andrey Bulatov Source Type: research

Clinical and Mechanistic Findings from MOTIF Trial: A Phase 2 Study Using Food Allergen Oral Immunotherapy for Cashew or Shrimp Allergy
Despite the success of peanut oral immunotherapy (OIT), there is little insight into the safety, efficacy, and immune underpinnings of OIT to treat cashew or shrimp allergy. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Andrea Fernandes, Shu Cao, Ella Parsons, Dinara Bogetic, Divya Kumar, Jessica Rogers, Debjani Ghoshal, Julia Thompson, Shu-Chen Lyu, Diane Dunham, Evan Do, Sofia Maysel-Auslender, Taryn Liu, Reyna Sharma, Andrew Chin, Andrew Long, Sheena Gupta, Kristine M Source Type: research