Primary, secondary and tertiary prevention of food allergy: current practices and future directions
Allergol Immunopathol (Madr). 2024 Mar 1;52(2):32-44. doi: 10.15586/aei.v52i2.1023. eCollection 2024.ABSTRACTThe incidence of food allergies has risen around the globe, and experts have been exploring methods of preventing such allergies in young children to ease the burden of disease and reduce the morbidity and mortality caused by anaphylaxis to food allergens. Such preventative measures can be categorised as primary, secondary and tertiary prevention, which are discussed in detail in this review. Primary prevention is defined as the prevention of becoming sensitised towards specific allergens. The evidence suggests that...
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Caoimhe Cronin Noah Salzberg Yuxin Woon Juan Trujillo Wurttele Source Type: research

Primary, secondary and tertiary prevention of food allergy: current practices and future directions
Allergol Immunopathol (Madr). 2024 Mar 1;52(2):32-44. doi: 10.15586/aei.v52i2.1023. eCollection 2024.ABSTRACTThe incidence of food allergies has risen around the globe, and experts have been exploring methods of preventing such allergies in young children to ease the burden of disease and reduce the morbidity and mortality caused by anaphylaxis to food allergens. Such preventative measures can be categorised as primary, secondary and tertiary prevention, which are discussed in detail in this review. Primary prevention is defined as the prevention of becoming sensitised towards specific allergens. The evidence suggests that...
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Caoimhe Cronin Noah Salzberg Yuxin Woon Juan Trujillo Wurttele Source Type: research

Primary, secondary and tertiary prevention of food allergy: current practices and future directions
Allergol Immunopathol (Madr). 2024 Mar 1;52(2):32-44. doi: 10.15586/aei.v52i2.1023. eCollection 2024.ABSTRACTThe incidence of food allergies has risen around the globe, and experts have been exploring methods of preventing such allergies in young children to ease the burden of disease and reduce the morbidity and mortality caused by anaphylaxis to food allergens. Such preventative measures can be categorised as primary, secondary and tertiary prevention, which are discussed in detail in this review. Primary prevention is defined as the prevention of becoming sensitised towards specific allergens. The evidence suggests that...
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Caoimhe Cronin Noah Salzberg Yuxin Woon Juan Trujillo Wurttele Source Type: research

Primary, secondary and tertiary prevention of food allergy: current practices and future directions
Allergol Immunopathol (Madr). 2024 Mar 1;52(2):32-44. doi: 10.15586/aei.v52i2.1023. eCollection 2024.ABSTRACTThe incidence of food allergies has risen around the globe, and experts have been exploring methods of preventing such allergies in young children to ease the burden of disease and reduce the morbidity and mortality caused by anaphylaxis to food allergens. Such preventative measures can be categorised as primary, secondary and tertiary prevention, which are discussed in detail in this review. Primary prevention is defined as the prevention of becoming sensitised towards specific allergens. The evidence suggests that...
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Caoimhe Cronin Noah Salzberg Yuxin Woon Juan Trujillo Wurttele Source Type: research

Primary, secondary and tertiary prevention of food allergy: current practices and future directions
Allergol Immunopathol (Madr). 2024 Mar 1;52(2):32-44. doi: 10.15586/aei.v52i2.1023. eCollection 2024.ABSTRACTThe incidence of food allergies has risen around the globe, and experts have been exploring methods of preventing such allergies in young children to ease the burden of disease and reduce the morbidity and mortality caused by anaphylaxis to food allergens. Such preventative measures can be categorised as primary, secondary and tertiary prevention, which are discussed in detail in this review. Primary prevention is defined as the prevention of becoming sensitised towards specific allergens. The evidence suggests that...
Source: Allergologia et Immunopathologia - March 9, 2024 Category: Allergy & Immunology Authors: Caoimhe Cronin Noah Salzberg Yuxin Woon Juan Trujillo Wurttele Source Type: research

Dietary composition of adult eosinophilic esophagitis patients is related to disease severity
ConclusionDietary composition may be related to inflammation in adult EoE patients. High-quality and anti-inflammatory diets may be a promising adjuvant therapy in the dietary management of EoE. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - March 9, 2024 Category: Allergy & Immunology Authors: Simone R. B. M. Eussen, Sanne Wielders, Willemijn E. de Rooij, Marleen T. J. Van Ampting, Betty C. A. M. Van Esch, Jeanne H. M. de Vries, Albert J. Bredenoord, Berber Vlieg ‐Boerstra Tags: ORIGINAL ARTICLE Source Type: research

Neutralizing IgG4 antibodies are a biomarker of sustained efficacy after peanut oral immunotherapy
(Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 7, 2024 Category: Allergy & Immunology Authors: Tarun Keswani, Nicole A. LaHood, Orlee Marini-Rapoport, Bijoya Karmakar, L éna Andrieux, Brian Reese, Sunny L. Sneed, Lars C. Pedersen, Geoffrey A. Mueller, Sarita U. Patil Source Type: research

Genome-wide identification of SWEET genes reveals their roles during seed development in peanuts
Sugar Will Eventually be Exported Transporter (SWEET) proteins are highly conserved in various organisms and play crucial roles in sugar transport processes. However, SWEET proteins in peanuts, an essential le... (Source: BMC Genomics)
Source: BMC Genomics - March 7, 2024 Category: Genetics & Stem Cells Authors: Yang Li, Mengjia Fu, Jiaming Li, Jie Wu, Zhenyang Shua, Tiantian Chen, Wen Yao and Dongxin Huai Tags: Research Source Type: research

Biochar loaded with root exudates of hyperaccumulator Leersia hexandra Swartz facilitated Cr(VI) reduction by shaping soil functional microbial communities
This study confirmed that root exudate-loaded peanut shell biochar reduced soil pH while simultaneously increasing DOC, sulfide, and Fe(II) concentrations, thereby facilitating the reduction of Cr(VI), achieving a reduction efficiency of 81.8%. Based on XPS and SEM elemental mapping analyses, Cr(VI) reduction occurred concurrently with the Fe and S redox cycles. Furthermore, the microbial diversity, abundance of the functional genera (Geobacter, Arthrobacter, and Desulfococcus) and the metabolic functions associated with Cr(VI) reduction were enhanced by root exudate-loaded biochar. Root exudate-loaded biochar can promote ...
Source: Chemosphere - March 6, 2024 Category: Chemistry Authors: Wendan Xiao Qi Zhang Miaojie Huang Shouping Zhao De Chen Na Gao Tianfen Chu Xuezhu Ye Source Type: research

Novel post-translationally cleaved Ara h 2 proteoforms: Purification, characterization and IgE-binding properties
Int J Biol Macromol. 2024 Mar 4:130613. doi: 10.1016/j.ijbiomac.2024.130613. Online ahead of print.ABSTRACTThe 2S albumins Ara h 2 and Ara h 6 have been shown to be the most important source of allergenicity in peanut. Several isoforms of these allergens have been described. Using extraction and liquid chromatography we isolated proteins with homology to Ara h 2 and characterized hitherto unknown Ara h 2 proteoforms with additional post-translational cleavage. High-resolution mass spectrometry located the cleavage site on the non-structured loop of Ara h 2 while far UV CD spectroscopy showed a comparable structure to Ara h...
Source: International Journal of Biological Macromolecules - March 6, 2024 Category: Biochemistry Authors: Stef J Koppelman Govardus A H de Jong Justin Marsh Phil Johnson Emily Dowell Marija Perusko Adrie Westphal Marianne van Hage Joseph Baumert Danijela Apostolovic Source Type: research

Biochar loaded with root exudates of hyperaccumulator Leersia hexandra Swartz facilitated Cr(VI) reduction by shaping soil functional microbial communities
This study confirmed that root exudate-loaded peanut shell biochar reduced soil pH while simultaneously increasing DOC, sulfide, and Fe(II) concentrations, thereby facilitating the reduction of Cr(VI), achieving a reduction efficiency of 81.8%. Based on XPS and SEM elemental mapping analyses, Cr(VI) reduction occurred concurrently with the Fe and S redox cycles. Furthermore, the microbial diversity, abundance of the functional genera (Geobacter, Arthrobacter, and Desulfococcus) and the metabolic functions associated with Cr(VI) reduction were enhanced by root exudate-loaded biochar. Root exudate-loaded biochar can promote ...
Source: Chemosphere - March 6, 2024 Category: Chemistry Authors: Wendan Xiao Qi Zhang Miaojie Huang Shouping Zhao De Chen Na Gao Tianfen Chu Xuezhu Ye Source Type: research

Biochar loaded with root exudates of hyperaccumulator Leersia hexandra Swartz facilitated Cr(VI) reduction by shaping soil functional microbial communities
This study confirmed that root exudate-loaded peanut shell biochar reduced soil pH while simultaneously increasing DOC, sulfide, and Fe(II) concentrations, thereby facilitating the reduction of Cr(VI), achieving a reduction efficiency of 81.8%. Based on XPS and SEM elemental mapping analyses, Cr(VI) reduction occurred concurrently with the Fe and S redox cycles. Furthermore, the microbial diversity, abundance of the functional genera (Geobacter, Arthrobacter, and Desulfococcus) and the metabolic functions associated with Cr(VI) reduction were enhanced by root exudate-loaded biochar. Root exudate-loaded biochar can promote ...
Source: Chemosphere - March 6, 2024 Category: Chemistry Authors: Wendan Xiao Qi Zhang Miaojie Huang Shouping Zhao De Chen Na Gao Tianfen Chu Xuezhu Ye Source Type: research

Novel post-translationally cleaved Ara h 2 proteoforms: Purification, characterization and IgE-binding properties
Int J Biol Macromol. 2024 Mar 4:130613. doi: 10.1016/j.ijbiomac.2024.130613. Online ahead of print.ABSTRACTThe 2S albumins Ara h 2 and Ara h 6 have been shown to be the most important source of allergenicity in peanut. Several isoforms of these allergens have been described. Using extraction and liquid chromatography we isolated proteins with homology to Ara h 2 and characterized hitherto unknown Ara h 2 proteoforms with additional post-translational cleavage. High-resolution mass spectrometry located the cleavage site on the non-structured loop of Ara h 2 while far UV CD spectroscopy showed a comparable structure to Ara h...
Source: International Journal of Biological Macromolecules - March 6, 2024 Category: Biochemistry Authors: Stef J Koppelman Govardus A H de Jong Justin Marsh Phil Johnson Emily Dowell Marija Perusko Adrie Westphal Marianne van Hage Joseph Baumert Danijela Apostolovic Source Type: research

Biochar loaded with root exudates of hyperaccumulator Leersia hexandra Swartz facilitated Cr(VI) reduction by shaping soil functional microbial communities
This study confirmed that root exudate-loaded peanut shell biochar reduced soil pH while simultaneously increasing DOC, sulfide, and Fe(II) concentrations, thereby facilitating the reduction of Cr(VI), achieving a reduction efficiency of 81.8%. Based on XPS and SEM elemental mapping analyses, Cr(VI) reduction occurred concurrently with the Fe and S redox cycles. Furthermore, the microbial diversity, abundance of the functional genera (Geobacter, Arthrobacter, and Desulfococcus) and the metabolic functions associated with Cr(VI) reduction were enhanced by root exudate-loaded biochar. Root exudate-loaded biochar can promote ...
Source: Chemosphere - March 6, 2024 Category: Chemistry Authors: Wendan Xiao Qi Zhang Miaojie Huang Shouping Zhao De Chen Na Gao Tianfen Chu Xuezhu Ye Source Type: research

High-density bin-based genetic map reveals a 530-kb chromosome segment derived from wild peanut contributing to late leaf spot resistance
In this study, a synthetic amphidiploid (Ipadur) of wild peanuts with high LLS resistance was used to cross with Tifrunner to construct TI population. In total, 200 recombinant inbred lines were collected for whole-genome resequencing. A high-density bin-based genetic linkage map was constructed, which includes 4,809 bin markers with an average inter-bin distance of 0.43 cM. The recombination across cultivated and wild species was unevenly distributed, providing a novel recombination landscape for cultivated-wild Arachis species. Using phenotyping data collected across three environments, 28 QTLs for LLS disease resistance...
Source: TAG. Theoretical and Applied Genetics - March 5, 2024 Category: Genetics & Stem Cells Authors: Jiaowen Pan Xiaojie Li Chun Fu Jianxin Bian Zhenyu Wang Conghui Yu Xiaoqin Liu Guanghao Wang Ruizheng Tian Xiaofeng Song Changsheng Li Han Xia Shuzhen Zhao Lei Hou Meng Gao Hailing Zi David Bertioli Soraya Leal-Bertioli Manish K Pandey Xingjun Wang Chuanz Source Type: research