Detection and identification of cis-regulatory elements using change-point and classification algorithms
Transcriptional regulation is primarily mediated by the binding of factors to non-coding regions in DNA. Identification of these binding regions enhances understanding of tissue formation and potentially facil... (Source: BMC Genomics)
Source: BMC Genomics - January 25, 2022 Category: Genetics & Stem Cells Authors: Dominic Maderazo, Jennifer A. Flegg, Manjula Algama, Mirana Ramialison and Jonathan Keith Tags: Methodology article Source Type: research

Correction to: Long read sequencing reveals novel isoforms and insights into splicing regulation during cell state changes
(Source: BMC Genomics)
Source: BMC Genomics - January 25, 2022 Category: Genetics & Stem Cells Authors: David J. Wright, Nicola A. L. Hall, Naomi Irish, Angela L. Man, Will Glynn, Arne Mould, Alejandro De Los Angeles, Emily Angiolini, David Swarbreck, Karim Gharbi, Elizabeth M. Tunbridge and Wilfried Haerty Tags: Correction Source Type: research

Transcriptome and methylome changes in two contrasting mungbean genotypes in response to drought stress
Due to drought stress, the growth, distribution, and production of mungbean is severely restricted. Previous study combining physiological and transcriptomic data indicated different genotypes of mungbean exhi... (Source: BMC Genomics)
Source: BMC Genomics - January 25, 2022 Category: Genetics & Stem Cells Authors: Peilei Zhao, Bao Ma, Chunmei Cai and Jihua Xu Tags: Research Source Type: research

AMPlify: attentive deep learning model for discovery of novel antimicrobial peptides effective against WHO priority pathogens
Antibiotic resistance is a growing global health concern prompting researchers to seek alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) are attracting attention again as therapeutic agen... (Source: BMC Genomics)
Source: BMC Genomics - January 25, 2022 Category: Genetics & Stem Cells Authors: Chenkai Li, Darcy Sutherland, S. Austin Hammond, Chen Yang, Figali Taho, Lauren Bergman, Simon Houston, Ren é L. Warren, Titus Wong, Linda M. N. Hoang, Caroline E. Cameron, Caren C. Helbing and Inanc Birol Tags: Research article Source Type: research

The genome of medicinal leech (Whitmania pigra) and comparative genomic study for exploration of bioactive ingredients
Leeches are classic annelids that have a huge diversity and are closely related to people, especially medicinal leeches. Medicinal leeches have been widely utilized in medicine based on the pharmacological act... (Source: BMC Genomics)
Source: BMC Genomics - January 24, 2022 Category: Genetics & Stem Cells Authors: Lei Tong, Shao-Xing Dai, De-Jun Kong, Peng-Peng Yang, Xin Tong, Xiang-Rong Tong, Xiao-Xu Bi, Yuan Su, Yu-Qi Zhao and Zi-Chao Liu Tags: Research article Source Type: research

A spatiotemporal atlas of the lepidopteran pest Helicoverpa armigera midgut provides insights into nutrient processing and pH regulation
Caterpillars from the insect order Lepidoptera are some of the most widespread and destructive agricultural pests. Most of their impact is at the larval stage, where the midgut epithelium mediates the digestio... (Source: BMC Genomics)
Source: BMC Genomics - January 24, 2022 Category: Genetics & Stem Cells Authors: Panagiotis Ioannidis, Benjamin Buer, Aris Ilias, Sofia Kaforou, Michalis Aivaliotis, Georgia Orfanoudaki, Vassilis Douris, Sven Geibel, John Vontas and Shane Denecke Tags: Research Source Type: research

Genome-wide survey of the dehydrin genes in bread wheat (Triticum aestivum L.) and its relatives: identification, evolution and expression profiling under various abiotic stresses
Bread wheat (Triticum aestivum) is an important staple cereal grain worldwide. The ever-increasing environmental stress makes it very important to mine stress-resistant genes for wheat breeding programs. Therefor... (Source: BMC Genomics)
Source: BMC Genomics - January 23, 2022 Category: Genetics & Stem Cells Authors: Yongchao Hao, Ming Hao, Yingjie Cui, Lingrang Kong and Hongwei Wang Tags: Research Source Type: research

Genome-wide association study of beef bull semen attributes
Cattle production is dependent upon fertility because it results in producing offspring to offset production costs. A number of semen attributes are believed to affect fertility and are frequently measured as ... (Source: BMC Genomics)
Source: BMC Genomics - January 23, 2022 Category: Genetics & Stem Cells Authors: M. L. Butler, A. R. Hartman, J. M. Bormann, R. L. Weaber, D. M. Grieger and M. M. Rolf Tags: Research Source Type: research

Third generation cephalosporin-resistant Klebsiella pneumoniae thriving in patients and in wastewater: what do they have in common?
Klebsiella pneumoniae are ubiquitous bacteria and recognized multidrug-resistant opportunistic pathogens that can be released into the environment, mainly through sewage, where they can survive even after wastewa... (Source: BMC Genomics)
Source: BMC Genomics - January 22, 2022 Category: Genetics & Stem Cells Authors: Jaqueline Rocha, Catarina Ferreira, Dalila Mil-Homens, Antonio Busquets, Ars énio M. Fialho, Isabel Henriques, Margarita Gomila and Célia M. Manaia Tags: Research Source Type: research

Comparative transcriptomics and eQTL mapping of response to Melampsora americana in selected Salix purpurea F2 progeny
Melampsora spp. rusts are the greatest pathogen threat to shrub willow (Salix spp.) bioenergy crops. Genetic resistance is key to limit the effects of these foliar diseases on host response and biomass yield, ho... (Source: BMC Genomics)
Source: BMC Genomics - January 22, 2022 Category: Genetics & Stem Cells Authors: Dustin G. Wilkerson, Chase R. Crowell, Craig H. Carlson, Patrick W. McMullen, Christine D. Smart and Lawrence B. Smart Tags: Research Source Type: research

Gene expression profiles in Malpighian tubules of the vector leafhopper Psammotettix striatus (L.) revealed regional functional diversity and heterogeneity
Many leafhoppers are known as pests and disease vectors of economically important plants. Previous studies of the physiological functions of vector leafhoppers have mainly focused on the salivary glands and th... (Source: BMC Genomics)
Source: BMC Genomics - January 21, 2022 Category: Genetics & Stem Cells Authors: Feimin Yuan and Cong Wei Tags: Research Source Type: research

Genome-scale analysis of genetic regulatory elements in Streptomyces avermitilis MA-4680 using transcript boundary information
The gram-positive bacterium, Streptomyces avermitilis, holds industrial importance as the producer of avermectin, a widely used anthelmintic agent, and a heterologous expression host of secondary metabolite-biosy... (Source: BMC Genomics)
Source: BMC Genomics - January 21, 2022 Category: Genetics & Stem Cells Authors: Yongjae Lee, Namil Lee, Soonkyu Hwang, Woori Kim, Suhyung Cho, Bernhard O. Palsson and Byung-Kwan Cho Tags: Research Source Type: research

Neural transcriptomic signature of chronic wasting disease in white-tailed deer
The increasing prevalence and expanding geographical range of the chronic wasting disease (CWD) panzootic in cervids is threatening human, animal, environmental and economic health. The pathogenesis of CWD in ... (Source: BMC Genomics)
Source: BMC Genomics - January 21, 2022 Category: Genetics & Stem Cells Authors: E óin O’Hara, Allen Herbst, Arun Kommadath, Judd M. Aiken, Debbie McKenzie, Negin Goodarzi, Pamela Skinner and Paul Stothard Tags: Research Source Type: research

Genome insights into the pharmaceutical and plant growth promoting features of the novel species Nocardia alni sp. nov
Recent studies highlighted the biosynthetic potential of nocardiae to produce diverse novel natural products comparable to that of Streptomyces, thereby making them an attractive source of new drug leads. Many of... (Source: BMC Genomics)
Source: BMC Genomics - January 21, 2022 Category: Genetics & Stem Cells Authors: Imen Nouioui, Sung-min Ha, Inwoo Baek, Jongsik Chun and Michael Goodfellow Tags: Research Source Type: research

Differential microRNA expression, microRNA arm switching, and microRNA:long noncoding RNA interaction in response to salinity stress in soybean
Soybean is a major legume crop with high nutritional and environmental values suitable for sustainable agriculture. Noncoding RNAs (ncRNAs), including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), are ... (Source: BMC Genomics)
Source: BMC Genomics - January 20, 2022 Category: Genetics & Stem Cells Authors: Chade Li, Wenyan Nong, Shancen Zhao, Xiao Lin, Yichun Xie, Ming-Yan Cheung, Zhixia Xiao, Annette Y. P. Wong, Ting Fung Chan, Jerome H. L. Hui and Hon-Ming Lam Tags: Research Source Type: research

Modified Northern blot protocol for easy detection of mRNAs in total RNA using radiolabeled probes
Northern blotting is still used as a gold standard for validation of the data obtained from high-throughput whole transcriptome-based methods. However, its disadvantages of lower sensitivity, labor-intensive o... (Source: BMC Genomics)
Source: BMC Genomics - January 20, 2022 Category: Genetics & Stem Cells Authors: Tao Yang, Mingdi Zhang and Nianhui Zhang Tags: Methodology article Source Type: research

Geometric morphology and population genomics provide insights into the adaptive evolution of Apis cerana in Changbai Mountain
Exploration of adaptive evolution of organisms in response to environmental change can help to understand the evolutionary history of species and the underlying mechanisms of adaptation to local environments, ... (Source: BMC Genomics)
Source: BMC Genomics - January 19, 2022 Category: Genetics & Stem Cells Authors: Liu Nannan, Liu Huamiao, Ju Yan, Li Xingan, Li Yang, Wang Tianjiao, He Jinming, Niu Qingsheng and Xing Xiumei Tags: Research Source Type: research

Ferroptosis-associated DNA methylation signature predicts overall survival in patients with head and neck squamous cell carcinoma
Head and neck squamous cell carcinoma (HNSCC) is a common cancer characterized by late diagnosis and poor prognosis. The aim of this study was to identify a novel ferroptosis-related DNA methylation signature ... (Source: BMC Genomics)
Source: BMC Genomics - January 18, 2022 Category: Genetics & Stem Cells Authors: Yuanyuan Xu, Min Hong, Deyu Kong, Jun Deng, Zhaoming Zhong and Jin Liang Tags: Research Source Type: research

The inconsistency between two major aneuploidy-screening platforms —single-nucleotide polymorphism array and next-generation sequencing—in the detection of embryo mosaicism
In preimplantation genetic testing for aneuploidy (PGT-A), appropriate evaluation of mosaic embryos is important because of the adverse implications of transferring embryos with high-level mosaicism or discard... (Source: BMC Genomics)
Source: BMC Genomics - January 18, 2022 Category: Genetics & Stem Cells Authors: Dongjia Chen, Yan Xu, Chenhui Ding, Yali Wang, Yu Fu, Bing Cai, Jing Wang, Rong Li, Jing Guo, Jiafu Pan, Yanhong Zeng, Yiping Zhong, Xiaoting Shen and Canquan Zhou Tags: Research Source Type: research

First analyses of lysine succinylation proteome and overlap between succinylation and acetylation in Solenopsis invicta Buren (Hymenoptera: Formicidae)
Lysine succinylation (Ksu) exists in both eukaryotes and prokaryotes, and influences a variety of metabolism processes. However, little attention has been paid to Ksu in insects, especially the notorious invas... (Source: BMC Genomics)
Source: BMC Genomics - January 17, 2022 Category: Genetics & Stem Cells Authors: Jingwen Ye and Jun Li Tags: Research Source Type: research

Identification of a ferroptosis-related gene pair biomarker with immune infiltration landscapes in ischemic stroke: a bioinformatics-based comprehensive study
Ischemic stroke (IS) is a principal contributor to long-term disability in adults. A new cell death mediated by iron is ferroptosis, characterized by lethal aggregation of lipid peroxidation. However, a paucit... (Source: BMC Genomics)
Source: BMC Genomics - January 16, 2022 Category: Genetics & Stem Cells Authors: Jiaxin Fan, Mengying Chen, Shuai Cao, Qingling Yao, Xiaodong Zhang, Shuang Du, Huiyang Qu, Yuxuan Cheng, Shuyin Ma, Meijuan Zhang, Yizhou Huang, Nan Zhang, Kaili Shi and Shuqin Zhan Tags: Research Source Type: research

Genome-wide analysis reveals the spatiotemporal expression patterns of SOS3 genes in the maize B73 genome in response to salt stress
Salt damage is an important abiotic stress that affects the growth and yield of maize worldwide. As an important member of the salt overly sensitive (SOS) signal transduction pathway, the SOS3 gene family part... (Source: BMC Genomics)
Source: BMC Genomics - January 16, 2022 Category: Genetics & Stem Cells Authors: Yunying Cao, Tingyu Shan, Hui Fang, Kangtai Sun, Wen Shi, Bei Tang, Junping Wu, Kai Wang, Ping Li and Baohua Wang Tags: Research Source Type: research

Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma
Lung carcinoma is a common geriatric disease. The development of genotype-targeted therapies greatly improved the management of lung carcinoma. However, the treatment for old patients can be more complex than ... (Source: BMC Genomics)
Source: BMC Genomics - January 15, 2022 Category: Genetics & Stem Cells Authors: Sixian Chen, Aizhen Fu, Yuan Lu, Wei Lu, Yongfeng Chen, Shuiqiang Hong, Suli Zhou, Tianmin Xiang, Zhenzhen Zhang and Yongguang Cai Tags: Research Source Type: research

Dictionary learning allows model-free pseudotime estimation of transcriptomic data
Pseudotime estimation from dynamic single-cell transcriptomic data enables characterisation and understanding of the underlying processes, for example developmental processes. Various pseudotime estimation met... (Source: BMC Genomics)
Source: BMC Genomics - January 15, 2022 Category: Genetics & Stem Cells Authors: Mona Rams and Tim O.F. Conrad Tags: Methodology article Source Type: research

Time-course RNASeq of Camponotus floridanus forager and nurse ant brains indicate links between plasticity in the biological clock and behavioral division of labor
Circadian clocks allow organisms to anticipate daily fluctuations in their environment by driving rhythms in physiology and behavior. Inter-organismal differences in daily rhythms, called chronotypes, exist an... (Source: BMC Genomics)
Source: BMC Genomics - January 15, 2022 Category: Genetics & Stem Cells Authors: Biplabendu Das and Charissa de Bekker Tags: Research article Source Type: research

Transcriptome analysis of Auricularia fibrillifera fruit-body responses to drought stress and rehydration
Drought stress severely restricts edible fungus production. The genus Auricularia has a rare drought tolerance, a rehydration capability, and is nutrient rich. (Source: BMC Genomics)
Source: BMC Genomics - January 15, 2022 Category: Genetics & Stem Cells Authors: Yiqin Wang, Zhifen Yang, Luxi Shi, Rui Yang, Hao Guo, Suqin Zhang and Guangdong Geng Tags: Research Source Type: research

Degradome comparison between wild and cultivated rice identifies differential targeting by miRNAs
Small non-coding (s)RNAs are involved in the negative regulation of gene expression, playing critical roles in genome integrity, development and metabolic pathways. Targeting of RNAs by ribonucleoprotein compl... (Source: BMC Genomics)
Source: BMC Genomics - January 14, 2022 Category: Genetics & Stem Cells Authors: Chenna Swetha, Anushree Narjala, Awadhesh Pandit, Varsha Tirumalai and P. V. Shivaprasad Tags: Research Source Type: research

Phenotypic and molecular characterization of a set of tropical maize inbred lines from a public breeding program in Brazil
The characterization of genetic diversity and population differentiation for maize inbred lines from breeding programs is of great value in assisting breeders in maintaining and potentially increasing the rate... (Source: BMC Genomics)
Source: BMC Genomics - January 14, 2022 Category: Genetics & Stem Cells Authors: Sirlene Viana de Faria, Leandro Tonello Zuffo, Wemerson Mendon ça Rezende, Diego Gonçalves Caixeta, Hélcio Duarte Pereira, Camila Ferreira Azevedo and Rodrigo Oliveira DeLima Tags: Research Source Type: research

Analysis of the transcriptome of the needles and bark of Pinus radiata induced by bark stripping and methyl jasmonate
Plants are attacked by diverse insect and mammalian herbivores and respond with different physical and chemical defences. Transcriptional changes underlie these phenotypic changes. Simulated herbivory has been... (Source: BMC Genomics)
Source: BMC Genomics - January 13, 2022 Category: Genetics & Stem Cells Authors: J. S. Nantongo, B. M. Potts, T. Frickey, E. Telfer, H. Dungey, H. Fitzgerald and J. M. O ’Reilly-Wapstra Tags: Research Source Type: research

Genome-wide investigation of microRNAs and expression profiles during rhizome development in ginger (Zingiber officinale Roscoe)
MicroRNAs (miRNAs) are endogenous, non-coding small functional RNAs that govern the post-transcriptional regulatory system of gene expression and control the growth and development of plants. Ginger is an herb... (Source: BMC Genomics)
Source: BMC Genomics - January 13, 2022 Category: Genetics & Stem Cells Authors: Haitao Xing, Yuan Li, Yun Ren, Ying Zhao, Xiaoli Wu and Hong-Lei Li Tags: Research Source Type: research

Integrated analysis of long non-coding RNAs and mRNAs reveals the regulatory network of maize seedling root responding to salt stress
Long non-coding RNAs (lncRNAs) play important roles in response to abiotic stresses in plants, by acting as cis- or trans-acting regulators of protein-coding genes. As a widely cultivated crop worldwide, maize... (Source: BMC Genomics)
Source: BMC Genomics - January 13, 2022 Category: Genetics & Stem Cells Authors: Peng Liu, Yinchao Zhang, Chaoying Zou, Cong Yang, Guangtang Pan, Langlang Ma and Yaou Shen Tags: Research Source Type: research

Combined PD-1/PD-L1 and tumor-infiltrating immune cells redefined a unique molecular subtype of high-grade serous ovarian carcinoma
High-grade serous ovarian carcinoma is highly heterogeneous, and although many studies have been conducted to identify high-grade serous ovarian carcinoma molecular subtypes that are sensitive to immunotherapy... (Source: BMC Genomics)
Source: BMC Genomics - January 13, 2022 Category: Genetics & Stem Cells Authors: Ping Liu, Ruoxu Chen, Xudong Zhang, Ruiting Fu, Lin Tao and Wei Jia Tags: Research Source Type: research

Identification of cardiomyopathy-related core genes through human metabolic networks and expression data
Cardiomyopathy is a complex type of myocardial disease, and its incidence has increased significantly in recent years. Dilated cardiomyopathy (DCM) and ischemic cardiomyopathy (ICM) are two common and indistin... (Source: BMC Genomics)
Source: BMC Genomics - January 12, 2022 Category: Genetics & Stem Cells Authors: Zherou Rong, Hongwei Chen, Zihan Zhang, Yue Zhang, Luanfeng Ge, Zhengyu Lv, Yuqing Zou, Junjie Lv, Yuehan He, Wan Li and Lina Chen Tags: Research Source Type: research

Genome-wide high-throughput signal peptide screening via plasmid pUC256E improves protease secretion in Lactiplantibacillus plantarum and Pediococcus acidilactici
Proteases catalyze the hydrolysis of peptide bonds of proteins, thereby improving dietary protein digestibility, nutrient availability, as well as flavor and texture of fermented food and feed products. The la... (Source: BMC Genomics)
Source: BMC Genomics - January 12, 2022 Category: Genetics & Stem Cells Authors: Binbin Chen, Bryan Zong Lin Loo, Ying Ying Cheng, Peng Song, Huan Fan, Oleg Latypov and Sandra Kittelmann Tags: Research Source Type: research

Spatiotemporal expression profile of novel and known small RNAs throughout rice plant development focussing on seed tissues
Small RNAs (sRNAs) regulate numerous plant processes directly related to yield, such as disease resistance and plant growth. To exploit this yield-regulating potential of sRNAs, the sRNA profile of one of the ... (Source: BMC Genomics)
Source: BMC Genomics - January 11, 2022 Category: Genetics & Stem Cells Authors: Anik ó Meijer, Tim De Meyer, Klaas Vandepoele and Tina Kyndt Tags: Research Source Type: research

A scaffold-level genome assembly of a minute pirate bug, Orius laevigatus (Hemiptera: Anthocoridae), and a comparative analysis of insecticide resistance-related gene families with hemipteran crop pests
Orius laevigatus, a minute pirate bug, is a highly effective beneficial predator of crop pests including aphids, spider mites and thrips in integrated pest management (IPM) programmes. No genomic information is ... (Source: BMC Genomics)
Source: BMC Genomics - January 11, 2022 Category: Genetics & Stem Cells Authors: Emma Bailey, Linda Field, Christopher Rawlings, Rob King, Fady Mohareb, Keywan-Hassani Pak, David Hughes, Martin Williamson, Eric Ganko, Benjamin Buer and Ralf Nauen Tags: Research Source Type: research

A modified decision tree approach to improve the prediction and mutation discovery for drug resistance in Mycobacterium tuberculosis
Drug resistant Mycobacterium tuberculosis is complicating the effective treatment and control of tuberculosis disease (TB). With the adoption of whole genome sequencing as a diagnostic tool, machine learning appr... (Source: BMC Genomics)
Source: BMC Genomics - January 11, 2022 Category: Genetics & Stem Cells Authors: Wouter Deelder, Gary Napier, Susana Campino, Luigi Palla, Jody Phelan and Taane G. Clark Tags: Research Source Type: research

RAD gene family analysis in cotton provides some key genes for flowering and stress tolerance in upland cotton G. hirsutum
RADIALIS (RAD), belongs to the MYB gene family and regulates a variety of functions including floral dorsoventral asymmetry in Antirrhinum majus and development of fruit proteins in Solanum lycopersicum. RAD gene... (Source: BMC Genomics)
Source: BMC Genomics - January 10, 2022 Category: Genetics & Stem Cells Authors: Nosheen Kabir, Xin Zhang, Le Liu, Ghulam Qanmber, Lian Zhang, Yu Xuan Wang, Zhuojing Sun, Na Zhao and Gang Wang Tags: Research Source Type: research

Genome-wide association studies for immunoglobulin concentrations in colostrum and serum in Chinese Holstein
The early death and health problems of calves caused substantial economic losses in the dairy industry. As the immune system of neonates has not been fully developed, the absorption of maternal immunoglobulin ... (Source: BMC Genomics)
Source: BMC Genomics - January 10, 2022 Category: Genetics & Stem Cells Authors: Shan Lin, Cuncun Ke, Lin Liu, Yahui Gao, Lingna Xu, Bo Han, Yaofeng Zhao, Shengli Zhang and Dongxiao Sun Tags: Research article Source Type: research

Long read sequencing reveals novel isoforms and insights into splicing regulation during cell state changes
Alternative splicing is a key mechanism underlying cellular differentiation and a driver of complexity in mammalian neuronal tissues. However, understanding of which isoforms are differentially used or express... (Source: BMC Genomics)
Source: BMC Genomics - January 10, 2022 Category: Genetics & Stem Cells Authors: David J. Wright, Nicola A. L. Hall, Naomi Irish, Angela L. Man, Will Glynn, Arne Mould, Alejandro De Los Angeles, Emily Angiolini, David Swarbreck, Karim Gharbi, Elizabeth M. Tunbridge and Wilfried Haerty Tags: Research article Source Type: research

Investigation of genetic relationships within three Miscanthus species using SNP markers identified with SLAF-seq
Miscanthus, which is a leading dedicated-energy grass in Europe and in parts of Asia, is expected to play a key role in the development of the future bioeconomy. However, due to its complex genetic background, it... (Source: BMC Genomics)
Source: BMC Genomics - January 10, 2022 Category: Genetics & Stem Cells Authors: Zhiyong Chen, Yancen He, Yasir Iqbal, Yanlan Shi, Hongmei Huang and Zili Yi Tags: Research article Source Type: research

Exploring the transportome of the biosurfactant producing yeast Starmerella bombicola
Starmerella bombicola is a non-conventional yeast mainly known for its capacity to produce high amounts of the glycolipids ‘sophorolipids’. Although its product has been used as biological detergent for a couple ... (Source: BMC Genomics)
Source: BMC Genomics - January 9, 2022 Category: Genetics & Stem Cells Authors: Silke Claus, Sylwia Jezierska, Liam D. H. Elbourne and Inge Van Bogaert Tags: Research Source Type: research

Long-read transcriptome sequencing provides insight into lignan biosynthesis during fruit development in Schisandra chinensis
Schisandra chinensis, an ancient member of the most basal angiosperm lineage which is known as the ANITA, is a fruit-bearing vine with the pharmacological effects of a multidrug system, such as antioxidant, anti... (Source: BMC Genomics)
Source: BMC Genomics - January 8, 2022 Category: Genetics & Stem Cells Authors: Chang Pyo Hong, Chang-Kug Kim, Dong Jin Lee, Hee Jeong Jeong, Yi Lee, Sin-Gi Park, Hyo-Jin Kim, Ji-Nam Kang, Hojin Ryu, Soo-Jin Kwon and Sang-Ho Kang Tags: Research Source Type: research

Computational modeling of chromatin accessibility identified important epigenomic regulators
Chromatin accessibility is essential for transcriptional activation of genomic regions. It is well established that transcription factors (TFs) and histone modifications (HMs) play critical roles in chromatin ... (Source: BMC Genomics)
Source: BMC Genomics - January 8, 2022 Category: Genetics & Stem Cells Authors: Yanding Zhao, Yadong Dong, Wei Hong, Chongming Jiang, Kevin Yao and Chao Cheng Tags: Research Source Type: research

Carriage of distinct blaKPC-2 and blaOXA-48 plasmids in a single ST11 hypervirulent Klebsiella pneumoniae isolate in Egypt
Carbapenem-resistant hypervirulent K. pneumoniae (CR-hvKP) causes serious infections with significant morbidity and mortality. However, the epidemiology and transmission mechanisms of CR-hvKP and the correspondin... (Source: BMC Genomics)
Source: BMC Genomics - January 8, 2022 Category: Genetics & Stem Cells Authors: Yanxian Yang, Yongqiang Yang, Mohamed Abd El-Gawad El-Sayed Ahmed, Mingyang Qin, Ruowen He, Yiping Wu, Xiaoxue Liang, Lan-Lan Zhong, Ping Chen, Baoguo Deng, Reem Mostafa Hassan, Weihong Wen, Lingqing Xu, Xubin Huang, Lin Xu and Guo-Bao Tian Tags: Research Source Type: research

Genome-wide identification and expression analysis of the coronatine-insensitive 1 (COI1) gene family in response to biotic and abiotic stresses in Saccharum
The coronatine insensitive 1 (COI1) gene is the core member of jasmonate signaling pathway, which is closely related to plant biotic and abiotic resistance. However, there have been no reports on COI1 in sugarcan... (Source: BMC Genomics)
Source: BMC Genomics - January 8, 2022 Category: Genetics & Stem Cells Authors: Tingting Sun, Yintian Meng, Guangli Cen, Aoyin Feng, Weihua Su, Yanling Chen, Chuihuai You, Youxiong Que and Yachun Su Tags: Research Source Type: research

oCEM: Automatic detection and analysis of overlapping co-expressed gene modules
When it comes to the co-expressed gene module detection, its typical challenges consist of overlap between identified modules and local co-expression in a subset of biological samples. The nature of module det... (Source: BMC Genomics)
Source: BMC Genomics - January 8, 2022 Category: Genetics & Stem Cells Authors: Quang-Huy Nguyen and Duc-Hau Le Tags: Software Source Type: research

Comprehensive analysis of the long noncoding RNA-associated competitive endogenous RNA network in the osteogenic differentiation of periodontal ligament stem cells
The mechanism implicated in the osteogenesis of human periodontal ligament stem cells (PDLSCs) has been investigated for years. Previous genomics data analyses showed that long noncoding RNA (lncRNA), microRNA... (Source: BMC Genomics)
Source: BMC Genomics - January 3, 2022 Category: Genetics & Stem Cells Authors: Lingzhi Lai, Zhaodan Wang, Yihong Ge, Wei Qiu, Buling Wu, Fuchun Fang, Huiyong Xu and Zhao Chen Tags: Research Source Type: research

New insights into the evolution of SPX gene family from algae to legumes; a focus on soybean
SPX-containing proteins have been known as key players in phosphate signaling and homeostasis. In Arabidopsis and rice, functions of some SPXs have been characterized, but little is known about their function ... (Source: BMC Genomics)
Source: BMC Genomics - December 30, 2021 Category: Genetics & Stem Cells Authors: Mahnaz Nezamivand-Chegini, Esmaeil Ebrahimie, Ahmad Tahmasebi, Ali Moghadam, Saeid Eshghi, Manijeh Mohammadi-Dehchesmeh, Stanislav Kopriva and Ali Niazi Tags: Research Source Type: research

Epigenetic features improve TALE target prediction
The yield of many crop plants can be substantially reduced by plant-pathogenic Xanthomonas bacteria. The infection strategy of many Xanthomonas strains is based on transcription activator-like effectors (TALEs), ... (Source: BMC Genomics)
Source: BMC Genomics - December 29, 2021 Category: Genetics & Stem Cells Authors: Annett Erkes, Stefanie M ücke, Maik Reschke, Jens Boch and Jan Grau Tags: Research Source Type: research