SNP-based and haplotype-based genome-wide association on drug dependence in Han Chinese
Drug addiction is a serious problem worldwide and is influenced by genetic factors. The present study aimed to investigate the association between genetics and drug addiction among Han Chinese. (Source: BMC Genomics)
Source: BMC Genomics - March 6, 2024 Category: Genetics & Stem Cells Authors: Hanli Xu, Yulin Kang, Tingming Liang, Sifen Lu, Xiaolin Xia, Zuhong Lu, Lingming Hu, Li Guo, Lishu Zhang, Jiaqiang Huang, Lin Ye, Peiye Jiang, Yi Liu, Li Xinyi, Jin Zhai, Zi Wang & hellip; Tags: Research Source Type: research
i5mC-DCGA: an improved hybrid network framework based on the CBAM attention mechanism for identifying promoter 5mC sites
5-Methylcytosine (5mC) plays a very important role in gene stability, transcription, and development. Therefore, accurate identification of the 5mC site is of key importance in genetic and pathological studies... (Source: BMC Genomics)
Source: BMC Genomics - March 5, 2024 Category: Genetics & Stem Cells Authors: Jianhua Jia, Rufeng Lei, Lulu Qin and Xin Wei Tags: Research Source Type: research
Loss of chromosome Y in regulatory T cells
Mosaic loss of chromosome Y (LOY) in leukocytes is the most prevalent somatic aneuploidy in aging humans. Men with LOY have increased risks of all-cause mortality and the major causes of death, including many ... (Source: BMC Genomics)
Source: BMC Genomics - March 5, 2024 Category: Genetics & Stem Cells Authors: Jonas Mattisson, Jonatan Halvardson, Hanna Davies, Bo żena Bruhn-Olszewska, Paweł Olszewski, Marcus Danielsson, Josefin Bjurling, Amanda Lindberg, Ammar Zaghlool, Edyta Rychlicka-Buniowska, Jan P. Dumanski and Lars A. Forsberg Tags: Research Source Type: research
Vitamin a potentiates sheep myoblasts myogenic differentiation through BHLHE40-modulated ID3 expression
Vitamin A and retinoic acid (RA, a metabolite of vitamin A), are inextricably involved to the development of skeletal muscle in animals. However, the mechanisms regulating skeletal muscle development by vitami... (Source: BMC Genomics)
Source: BMC Genomics - March 5, 2024 Category: Genetics & Stem Cells Authors: Pengkang Song, Jiamin Zhao, Weipeng Zhang, Xuying Li, Bingzhen Ji and Junxing Zhao Tags: Research Source Type: research
Characterization of rumen microbiome and immune genes expression of crossbred beef steers with divergent residual feed intake phenotypes
We investigated whole blood and hepatic mRNA expressions of immune genes and rumen microbiome of crossbred beef steers with divergent residual feed intake phenotype to identify relevant biological processes un... (Source: BMC Genomics)
Source: BMC Genomics - March 5, 2024 Category: Genetics & Stem Cells Authors: Godstime Taiwo, Olanrewaju B. Morenikeji, Modoluwamu Idowu, Taylor Sidney, Ajiboye Adekunle, Andres Pech Cervantes, Sunday Peters and Ibukun M. Ogunade Tags: Research Source Type: research
The first Cyclospora cayetanensis lineage A genome from an isolate from Mexico
Cyclospora cayetanensis is a protozoan parasite that causes intestinal illness in humans worldwide. Despite its global distribution, most genomic data for C. cayetanensis has been obtained from isolates collected... (Source: BMC Genomics)
Source: BMC Genomics - March 5, 2024 Category: Genetics & Stem Cells Authors: Monica Santin, Aleksey Molokin, Guadalupe E. Orozco-Mosqueda, Sonia Almeria and Jenny Maloney Tags: Research Source Type: research
Evaluation of aphid resistance on different rose cultivars and transcriptome analysis in response to aphid infestation
The rose is one of the most important ornamental flowers in the world for its aesthetic beauty but can be attacked by many pests such as aphids. Aphid infestation causes tremendous damage on plant tissues lead... (Source: BMC Genomics)
Source: BMC Genomics - March 4, 2024 Category: Genetics & Stem Cells Authors: Wenqi Dong, Lei Sun, Bo Jiao, Pu Zhao, Chunhong Ma, Junping Gao and Shuo Zhou Tags: Research Source Type: research
De novo assembly and annotation of the Patagonian toothfish (Dissostichus eleginoides) genome
Patagonian toothfish (Dissostichus eleginoides) is an economically and ecologically important fish species in the family Nototheniidae. Juveniles occupy progressively deeper waters as they mature and grow, and ad... (Source: BMC Genomics)
Source: BMC Genomics - March 4, 2024 Category: Genetics & Stem Cells Authors: David Ryder, David Stone, Diana Minardi, Ainsley Riley, Justin Avant, Lisa Cross, Marta Soeffker, Deborah Davidson, Andrew Newman, Peter Thomson, Chris Darby and Ronny van Aerle Tags: Research Source Type: research
An across breed, diet and tissue analysis reveals the transcription factor NR1H3 as a key mediator of residual feed intake in beef cattle
Provision of feed is a major determinant of overall profitability in beef production systems, accounting for up to 75% of the variable costs. Thus, improving cattle feed efficiency, by way of determining the u... (Source: BMC Genomics)
Source: BMC Genomics - March 4, 2024 Category: Genetics & Stem Cells Authors: Kate Keogh, D. A. Kenny, P. A. Alexandre, M. McGee and A. Reverter Tags: Research Source Type: research
The first two whole mitochondrial genomes for the genus Dactylis species: assembly and comparative genomics analysis
Orchardgrass (Dactylis glomerata L.), a perennial forage, has the advantages of rich leaves, high yield, and good quality and is one of the most significant forage for grassland animal husbandry and ecological ma... (Source: BMC Genomics)
Source: BMC Genomics - March 4, 2024 Category: Genetics & Stem Cells Authors: Guangyan Feng, Yongjuan Jiao, Huizhen Ma, Haoyang Bian, Gang Nie, Linkai Huang, Zheni Xie, Qifan Ran, Wenwen Fan, Wei He and Xinquan Zhang Tags: Research Source Type: research
Insight into telomere regulation: road to discovery and intervention in plasma drug-protein targets
Telomere length is a critical metric linked to aging, health, and disease. Currently, the exploration of target proteins related to telomere length is usually limited to the context of aging and specific disea... (Source: BMC Genomics)
Source: BMC Genomics - March 2, 2024 Category: Genetics & Stem Cells Authors: Kaixi Ding, Juejue Zhangwang, Ming Lei and Chunping Xiong Tags: Research Source Type: research
Characterization and mitigation of artifacts derived from NGS library preparation due to structure-specific sequences in the human genome
Hybridization capture-based targeted next generation sequencing (NGS) is gaining importance in routine cancer clinical practice. DNA library preparation is a fundamental step to produce high-quality sequencing... (Source: BMC Genomics)
Source: BMC Genomics - March 1, 2024 Category: Genetics & Stem Cells Authors: HuiJuan Chen, YiRan Zhang, Bing Wang, Rui Liao, XiaoHong Duan, ChunYan Yang, Jing Chen, YanTong Hao, YingShuang Shu, LiLi Cai, Xue Leng, Nian-Song Qian, DaWei Sun, Beifang Niu and Qiming Zhou Tags: Research Source Type: research
Genome-wide analysis and functional validation reveal the role of late embryogenesis abundant genes in strawberry (Fragaria × ananassa) fruit ripening
Late embryogenesis abundant (LEA) proteins play important roles in plant growth and development, as well as stresses responsiveness. Nowadays, it has been found that LEAs also have function in fruit ripening. ... (Source: BMC Genomics)
Source: BMC Genomics - March 1, 2024 Category: Genetics & Stem Cells Authors: Yuanxiu Lin, Musha She, Mantong Zhao, Hong Yu, Wenfei Xiao, Yunting Zhang, Mengyao Li, Qing Chen, Yong Zhang, Yan Wang, Wen He, Xiaorong Wang, Haoru Tang and Ya Luo Tags: Research Source Type: research
Regulation of endogenous hormone and miRNA in leaves of alfalfa (Medicago sativa L.) seedlings under drought stress by endogenous nitric oxide
Alfalfa (Medicago sativa. L) is one of the best leguminous herbage in China and even in the world, with high nutritional and ecological value. However, one of the drawbacks of alfalfa is its sensitivity to dry co... (Source: BMC Genomics)
Source: BMC Genomics - March 1, 2024 Category: Genetics & Stem Cells Authors: Qian Ruan, Xiaoming Bai, Yizhen Wang, Xiaofang Zhang, Baoqiang Wang, Ying Zhao, Xiaolin Zhu and Xiaohong Wei Tags: Research Source Type: research
Targeted next-generation sequencing and long-read HiFi sequencing provide novel insights into clinically significant KLF1 variants
Kr üppel-like factor 1 (KLF1), a crucial erythroid transcription factor, plays a significant role in various erythroid changes and haemolytic diseases. The rare erythrocyte Lutheran inhibitor (In(Lu)) blood gro... (Source: BMC Genomics)
Source: BMC Genomics - March 1, 2024 Category: Genetics & Stem Cells Authors: Luyi Ye, Chen Wang, Aijing Li, Minghao Li, Yan Pi, Jingmin Yang, Ziyan Zhu and Daru Lu Tags: Research Source Type: research
