Star allele search: a pharmacogenetic annotation database and user-friendly search tool of publicly available 1000 Genomes Project biospecimens
Here we describe a new public pharmacogenetic (PGx) annotation database of a large (n = 3,202) and diverse biospecimen collection of 1000 Genomes Project cell lines and DNAs. The database is searchable with a use... (Source: BMC Genomics)
Source: BMC Genomics - January 26, 2024 Category: Genetics & Stem Cells Authors: N. Gharani, G. Calendo, D. Kusic, J. Madzo and L. Scheinfeldt Tags: Database Source Type: research
ECDEP: identifying essential proteins based on evolutionary community discovery and subcellular localization
In cellular activities, essential proteins play a vital role and are instrumental in comprehending fundamental biological necessities and identifying pathogenic genes. Current deep learning approaches for pred... (Source: BMC Genomics)
Source: BMC Genomics - January 26, 2024 Category: Genetics & Stem Cells Authors: Chen Ye, Qi Wu, Shuxia Chen, Xuemei Zhang, Wenwen Xu, Yunzhi Wu, Youhua Zhang and Yi Yue Tags: Research Source Type: research
Identification of ARF genes in Cucurbita pepo L and analysis of expression patterns, and functional analysis of CpARF22 under drought, salt stress
Auxin transcription factor (ARF) is an important transcription factor that transmits auxin signals and is involved in plant growth and development as well as stress response. However, genome-wide identificatio... (Source: BMC Genomics)
Source: BMC Genomics - January 25, 2024 Category: Genetics & Stem Cells Authors: Ming-jun Zhang, Ying-yu Xue, Shuang Xu, Xuan-ru Jin and Xing-chu Man Tags: Research Source Type: research
Differential gene expression and microRNA profile in corpora allata-corpora cardiaca of Aedes aegypti mosquitoes with weak juvenile hormone signalling
The corpora allata-corpora cardiaca (CA-CC) is an endocrine gland complex that regulates mosquito development and reproduction through the synthesis of juvenile hormone (JH). Epoxidase (Epox) is a key enzyme in t... (Source: BMC Genomics)
Source: BMC Genomics - January 25, 2024 Category: Genetics & Stem Cells Authors: Zhi Qi, Kayvan Etebari, Marcela Nouzova, Fernando G. Noriega and Sassan Asgari Tags: Research Source Type: research
Decoding the complete organelle genomic architecture of Stewartia gemmata: an early-diverging species in Theaceae
Theaceae, comprising 300 + species, holds significance in biodiversity, economics, and culture, notably including the globally consumed tea plant. Stewartia gemmata, a species of the earliest diverging tribe Stew... (Source: BMC Genomics)
Source: BMC Genomics - January 25, 2024 Category: Genetics & Stem Cells Authors: Daliang Liu, Zhihan Zhang, Yanlin Hao, Mengge Li, Houlin Yu, Xingruo Zhang, Haoyang Mi, Lin Cheng and Yiyong Zhao Tags: Research Source Type: research
High-fidelity (repeat) consensus sequences from short reads using combined read clustering and assembly
Despite the many cheap and fast ways to generate genomic data, good and exact genome assembly is still a problem, with especially the repeats being vastly underrepresented and often misassembled. As short read... (Source: BMC Genomics)
Source: BMC Genomics - January 24, 2024 Category: Genetics & Stem Cells Authors: Ludwig Mann, Kristin Balasch, Nicola Schmidt and Tony Heitkam Tags: Software Source Type: research
Genome-wide identification of B-box zinc finger (BBX) gene family in Medicago sativa and their roles in abiotic stress responses
B-box (BBX) family is a class of zinc finger transcription factors (TFs) that play essential roles in regulating plant growth, development, as well as abiotic stress. However, no systematic analysis of BBX genes ... (Source: BMC Genomics)
Source: BMC Genomics - January 24, 2024 Category: Genetics & Stem Cells Authors: Shuxia Li, Shuaiqi Guo, Xueqin Gao, Xiaotong Wang, Yaling Liu, Jing Wang, Xiaohong Li, Jinqing Zhang and Bingzhe Fu Tags: Research Source Type: research
Comparative transcriptomic analysis of the different developmental stages of ovary in the cuttlefish Sepia pharaonis
The cuttlefish, Sepia pharaonis, is characterized by rapid growth and strong disease resistance, making it an important commercially farmed cephalopod species in the southeastern coastal regions of China. However... (Source: BMC Genomics)
Source: BMC Genomics - January 23, 2024 Category: Genetics & Stem Cells Authors: Maowang Jiang, Qingxi Han, Liting Xu, Ruibing Peng, Tao Zhang and Xiamin Jiang Tags: Research Source Type: research
Causal association between 637 human metabolites and ovarian cancer: a mendelian randomization study
This study employs Mendelian randomization (MR... (Source: BMC Genomics)
Source: BMC Genomics - January 23, 2024 Category: Genetics & Stem Cells Authors: Yedong Huang, Wenyu Lin and Xiangqin Zheng Tags: Research Source Type: research
Genome-wide association study identifies genetic variants underlying footrot in Portuguese Merino sheep
Ovine footrot caused by Dichelobacter nodosus (D. nodosus) is a contagious disease with serious economic and welfare impacts in sheep production systems worldwide. A better understanding of the host genetic archi... (Source: BMC Genomics)
Source: BMC Genomics - January 23, 2024 Category: Genetics & Stem Cells Authors: Daniel Gaspar, Catarina Ginja, Nuno Carolino, C élia Leão, Helena Monteiro, Lino Tábuas, Sandra Branco, Ludovina Padre, Pedro Caetano, Ricardo Romão, Claudino Matos, António Marcos Ramos, Elisa Bettencourt and Ana Usié Tags: Research Source Type: research
Computational analysis of the AP2/ERF family in crops genome
The Apetala 2/ethylene-responsive factor family has diverse functions that enhance development and torment resistance in the plant genome. In variation, the ethylene-responsive factor (ERF) family of TF ’s genes i... (Source: BMC Genomics)
Source: BMC Genomics - January 23, 2024 Category: Genetics & Stem Cells Authors: Shouhartha Choudhury Tags: Research Source Type: research
Integrative genomic analyses reveal putative cell type-specific targets of the Drosophila ets transcription factor Pointed
The Ets domain transcription factors direct diverse biological processes throughout all metazoans and are implicated in development as well as in tumor initiation, progression and metastasis. The Drosophila Ets t... (Source: BMC Genomics)
Source: BMC Genomics - January 23, 2024 Category: Genetics & Stem Cells Authors: Komal Kumar Bollepogu Raja, Kelvin Yeung, Yoon-Kyung Shim and Graeme Mardon Tags: Research Source Type: research
Pseudogenomic insights into the evolution of Mycobacterium ulcerans
Buruli ulcer (BU) disease, caused by Mycobacterium ulcerans (MU), and characterized by necrotic ulcers is still a health problem in Africa and Australia. The genome of the bacterium has several pseudogenes due to... (Source: BMC Genomics)
Source: BMC Genomics - January 22, 2024 Category: Genetics & Stem Cells Authors: Edwin Sakyi Kyei-Baffour, Kwabena Owusu-Boateng, Abiola Isawumi and Lydia Mosi Tags: Research Source Type: research
Characterization of the pyruvate kinase gene family in soybean and identification of a putative salt responsive gene GmPK21
As a key regulatory enzyme in the glycolysis pathway, pyruvate kinase (PK) plays crucial roles in multiple physiological processes during plant growth and is also involved in the abiotic stress response. Howev... (Source: BMC Genomics)
Source: BMC Genomics - January 22, 2024 Category: Genetics & Stem Cells Authors: Wei Liu, Yubin Wang, Yanwei Zhang, Wei Li, Caijie Wang, Ran Xu, Haiying Dai and Lifeng Zhang Tags: Research Source Type: research
Mitochondrial genome provides species-specific targets for the rapid detection of early invasive populations of Hylurgus ligniperda in China
Hylurgus ligniperda, a major international forestry quarantine pest, was recently found to have invaded and posed a serious threat to the Pinus forests of the Jiaodong Peninsula in China. Continuous monitoring an... (Source: BMC Genomics)
Source: BMC Genomics - January 22, 2024 Category: Genetics & Stem Cells Authors: Chengjin Li, Buxin Wang, Yingchao Ji, Lan Huang, Xiaoyi Wang, Wenxia Zhao, Yanhong Wang, Hongyi Wang and Yanxia Yao Tags: Research Source Type: research
