Chromatin profiling reveals TFAP4 as a critical transcriptional regulator of bovine satellite cell differentiation
Satellite cells are myogenic precursor cells in adult skeletal muscle and play a crucial role in skeletal muscle regeneration, maintenance, and growth. Like embryonic myoblasts, satellite cells have the abilit... (Source: BMC Genomics)
Source: BMC Genomics - March 12, 2024 Category: Genetics & Stem Cells Authors: Pengcheng Lyu and Honglin Jiang Tags: Research Source Type: research
Shared and distinct interactions of type 1 and type 2 Epstein-Barr Nuclear Antigen 2 with the human genome
There are two major genetic types of Epstein-Barr Virus (EBV): type 1 (EBV-1) and type 2 (EBV-2). EBV functions by manipulating gene expression in host B cells, using virus-encoded gene regulatory proteins inc... (Source: BMC Genomics)
Source: BMC Genomics - March 12, 2024 Category: Genetics & Stem Cells Authors: Kenyatta C. M. F. Viel, Sreeja Parameswaran, Omer A. Donmez, Carmy R. Forney, Matthew R. Hass, Cailing Yin, Sydney H. Jones, Hayley K. Prosser, Arame A. Diouf, Olivia E. Gittens, Lee E. Edsall, Xiaoting Chen, Hope Rowden, Katelyn A. Dunn, Rui Guo, Andrew Tags: Research Source Type: research
Allelic variation in the autotetraploid potato: genes involved in starch and steroidal glycoalkaloid metabolism as a case study
Tuber starch and steroidal glycoalkaloid (SGA)-related traits have been consistently prioritized in potato breeding, while allelic variation pattern of genes that underlie these traits is less explored. (Source: BMC Genomics)
Source: BMC Genomics - March 12, 2024 Category: Genetics & Stem Cells Authors: Hongbo Li, Matthijs Brouwer, Elena Del Pup, Natascha van Lieshout, Richard Finkers, Christian W. B. Bachem and Richard G. F. Visser Tags: Research Source Type: research
Distribution patterns of molecular markers of antimalarial drug resistance in Plasmodium falciparum isolates on the Thai-Myanmar border during the periods of 1993 –1998 and 2002–2008
Polymorphisms of Plasmodium falciparum chloroquine resistance transporter (pfcrt), Plasmodium falciparum multi-drug resistance 1 (pfmdr1) and Plasmodium falciparum kelch 13-propeller (pfk13) genes are accepted as... (Source: BMC Genomics)
Source: BMC Genomics - March 11, 2024 Category: Genetics & Stem Cells Authors: Phunuch Muhamad, Papichaya Phompradit, Wanna Chaijaroenkul and Kesara Na-Bangchang Tags: Research Source Type: research
Multi-Omics integration can be used to rescue metabolic information for some of the dark region of the Pseudomonas putida proteome
In every omics experiment, genes or their products are identified for which even state of the art tools are unable to assign a function. In the biotechnology chassis organism Pseudomonas putida, these proteins of... (Source: BMC Genomics)
Source: BMC Genomics - March 11, 2024 Category: Genetics & Stem Cells Authors: Steven Tavis and Robert L. Hettich Tags: Research Source Type: research
Structural and functional characterization of genes PYL-PP2C-SnRK2s in the ABA signalling pathway of Cucurbita pepo
The core regulation of the abscisic acid (ABA) signalling pathway comprises the multigenic families PYL, PP2C, and SnRK2. In this work, we conducted a genome-wide study of the components of these families in Cucu... (Source: BMC Genomics)
Source: BMC Genomics - March 11, 2024 Category: Genetics & Stem Cells Authors: Jessica Iglesias-Moya, Álvaro Benítez, María Segura, Sonsoles Alonso, Dolores Garrido, Cecilia Martínez and Manuel Jamilena Tags: Research Source Type: research
Genomic dissection of the correlation between milk yield and various health traits using functional and evolutionary information about imputed sequence variants of 34,497 German Holstein cows
Over the last decades, it was subject of many studies to investigate the genomic connection of milk production and health traits in dairy cattle. Thereby, incorporating functional information in genomic analys... (Source: BMC Genomics)
Source: BMC Genomics - March 9, 2024 Category: Genetics & Stem Cells Authors: Helen Schneider, Ana-Marija Krizanac, Clemens Falker-Gieske, Johannes Heise, Jens Tetens, Georg Thaller and J örn Bennewitz Tags: Research Source Type: research
DNA-QLC: an efficient and reliable image encoding scheme for DNA storage
DNA storage has the advantages of large capacity, long-term stability, and low power consumption relative to other storage mediums, making it a promising new storage medium for multimedia information such as i... (Source: BMC Genomics)
Source: BMC Genomics - March 9, 2024 Category: Genetics & Stem Cells Authors: Yanfen Zheng, Ben Cao, Xiaokang Zhang, Shuang Cui, Bin Wang and Qiang Zhang Tags: Research Source Type: research
High genetic diversity of the himalayan marmot relative to plague outbreaks in the Qinghai-Tibet Plateau, China
Plague, as an ancient zoonotic disease caused by Yersinia pestis, has brought great disasters. The natural plague focus of Marmota himalayana in the Qinghai-Tibet Plateau is the largest, which has been constantly... (Source: BMC Genomics)
Source: BMC Genomics - March 8, 2024 Category: Genetics & Stem Cells Authors: Ying Ma, Pengbo Liu, Ziyan Li, Yujuan Yue, Yanmei Zhao, Jian He, Jiaxin Zhao, Xiuping Song, Jun Wang, Qiyong Liu and Liang Lu Tags: Research Source Type: research
Genome mining of Escherichia coli WG5D from drinking water source: unraveling antibiotic resistance genes, virulence factors, and pathogenicity
Escherichia coli, a ubiquitous inhabitant of the gut microbiota, has been recognized as an indicator of fecal contamination and a potential reservoir for antibiotic resistance genes. Its prevalence in drinking wa... (Source: BMC Genomics)
Source: BMC Genomics - March 8, 2024 Category: Genetics & Stem Cells Authors: Oluwaseyi Samuel Olanrewaju, Lesego G Molale-Tom, Rinaldo K Kritzinger and Cornelius Carlos Bezuidenhout Tags: Research Source Type: research
scFSNN: a feature selection method based on neural network for single-cell RNA-seq data
While single-cell RNA sequencing (scRNA-seq) allows researchers to analyze gene expression in individual cells, its unique characteristics like over-dispersion, zero-inflation, high gene-gene correlation, and ... (Source: BMC Genomics)
Source: BMC Genomics - March 8, 2024 Category: Genetics & Stem Cells Authors: Minjiao Peng, Baoqin Lin, Jun Zhang, Yan Zhou and Bingqing Lin Tags: Research Source Type: research
Comparative analysis of the organelle genomes of Aconitum carmichaelii revealed structural and sequence differences and phylogenetic relationships
In this study, we conducted an assembly and analysis of the organelle genomes of Aconitum carmichaelii. Our investigation encompassed the examination of organelle genome structures, gene transfer events, and the ... (Source: BMC Genomics)
Source: BMC Genomics - March 8, 2024 Category: Genetics & Stem Cells Authors: Rongxiang Zhang, Niyan Xiang, Changjiang Qian, Shuwen Liu, Yuemei Zhao, Guiyu Zhang, Pei Wei, Jianfeng Li and Tao Yuan Tags: Research Source Type: research
Genome-wide analysis of acid tolerance genes of Enterococcus faecalis with RNA-seq and Tn-seq
Enterococcus faecalis, a formidable nosocomial and community-acquired opportunistic pathogen, can persist a wide range of extreme environments, including low pH and nutrient deficiency. Clarifying the survival me... (Source: BMC Genomics)
Source: BMC Genomics - March 8, 2024 Category: Genetics & Stem Cells Authors: Zhanyi Chen, Chenguang Niu, Lifan Wei, Zhengwei Huang and Shujun Ran Tags: Research Source Type: research
Coping with extremes: the rumen transcriptome and microbiome co-regulate plateau adaptability of Xizang goat
The interactions between the rumen microbiota and the host are crucial for the digestive and absorptive processes of ruminants, and they are heavily influenced by the climatic conditions of their habitat. Owin... (Source: BMC Genomics)
Source: BMC Genomics - March 7, 2024 Category: Genetics & Stem Cells Authors: Cheng Pan, Haiyan Li, Shehr Bano Mustafa, Cuomu Renqing, Zhenzhen Zhang, Jingjing Li, Tianzeng Song, Gaofu Wang and Wangsheng Zhao Tags: Research Source Type: research
Genome-wide identification of SWEET genes reveals their roles during seed development in peanuts
Sugar Will Eventually be Exported Transporter (SWEET) proteins are highly conserved in various organisms and play crucial roles in sugar transport processes. However, SWEET proteins in peanuts, an essential le... (Source: BMC Genomics)
Source: BMC Genomics - March 7, 2024 Category: Genetics & Stem Cells Authors: Yang Li, Mengjia Fu, Jiaming Li, Jie Wu, Zhenyang Shua, Tiantian Chen, Wen Yao and Dongxin Huai Tags: Research Source Type: research
