An evolutionary view of the Fusarium core genome
Fusarium, a member of the Ascomycota fungi, encompasses several pathogenic species significant to plants and animals. Some phytopathogenic species have received special attention due to their negative economic im... (Source: BMC Genomics)
Source: BMC Genomics - March 22, 2024 Category: Genetics & Stem Cells Authors: Daniel A. Gomez-Chavarria, Alvaro L. Rua-Giraldo and Juan F. Alzate Tags: Research Source Type: research

Exploring the ageing methylome in the model insect, Nasonia vitripennis
The ageing process is a multifaceted phenomenon marked by the gradual deterioration of cellular and organismal functions, accompanied by an elevated susceptibility to diseases. The intricate interplay between ... (Source: BMC Genomics)
Source: BMC Genomics - March 22, 2024 Category: Genetics & Stem Cells Authors: K. Brink, C. L. Thomas, A. Jones, T. W. Chan and E. B. Mallon Tags: Research Source Type: research

GNNMF: a multi-view graph neural network for ATAC-seq motif finding
The Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) utilizes the Transposase Tn5 to probe open chromatic, which simultaneously reveals multiple transcription factor binding sites (TFBSs)... (Source: BMC Genomics)
Source: BMC Genomics - March 21, 2024 Category: Genetics & Stem Cells Authors: Shuangquan Zhang, Xiaotian Wu, Zhichao Lian, Chunman Zuo and Yan Wang Tags: Research Source Type: research

Chromatin accessibility and H3K9me3 landscapes reveal long-term epigenetic effects of fetal-neonatal iron deficiency in rat hippocampus
Iron deficiency (ID) during the fetal-neonatal period results in long-term neurodevelopmental impairments associated with pervasive hippocampal gene dysregulation. Prenatal choline supplementation partially no... (Source: BMC Genomics)
Source: BMC Genomics - March 21, 2024 Category: Genetics & Stem Cells Authors: Shirelle X. Liu, Aarthi Ramakrishnan, Li Shen, Jonathan C. Gewirtz, Michael K. Georgieff and Phu V. Tran Tags: Research Source Type: research

RNA-seq analysis reveals changes in mRNA expression during development in Daphnia mitsukuri
Temporal transcriptional variation is a major contributor to functional evolution and the developmental process. Parthenogenetic water fleas of the genus Daphnia (Cladocera) provide an ideal model to characterize... (Source: BMC Genomics)
Source: BMC Genomics - March 21, 2024 Category: Genetics & Stem Cells Authors: Xiuping Zhang, Wenwu Yang, David Blair, Wei Hu and Mingbo Yin Tags: Research Source Type: research

Sex and fetal genome influence gene expression in pig endometrium at the end of gestation
A fine balance of feto-maternal resource allocation is required to support pregnancy, which depends on interactions between maternal and fetal genetic potential, maternal nutrition and environment, endometrial... (Source: BMC Genomics)
Source: BMC Genomics - March 21, 2024 Category: Genetics & Stem Cells Authors: Agnes Bonnet, Lisa Bluy, Laure Gress, Laurianne Canario, Laure Ravon, Aurelie S écula, Yvon Billon and Laurence Liaubet Tags: Research Source Type: research

Identification and characterization of structural variants related to meat quality in pigs using chromosome-level genome assemblies
Many studies have been performed to identify various genomic loci and genes associated with the meat quality in pigs. However, the full genetic architecture of the trait still remains unclear in part because o... (Source: BMC Genomics)
Source: BMC Genomics - March 21, 2024 Category: Genetics & Stem Cells Authors: Daehong Kwon, Nayoung Park, Suyeon Wy, Daehwan Lee, Woncheoul Park, Han-Ha Chai, In-Cheol Cho, Jongin Lee, Kisang Kwon, Heesun Kim, Youngbeen Moon, Juyeon Kim and Jaebum Kim Tags: Research Source Type: research

Uncovering a multitude of stage-specific splice variants and putative protein isoforms generated along mouse spermatogenesis
Mammalian testis is a highly complex and heterogeneous tissue. This complexity, which mostly derives from spermatogenic cells, is reflected at the transcriptional level, with the largest number of tissue-speci... (Source: BMC Genomics)
Source: BMC Genomics - March 20, 2024 Category: Genetics & Stem Cells Authors: Carlos Romeo-Cardeillac, Mar ía Fernanda Trovero, Santiago Radío, Pablo Smircich, Rosana Rodríguez-Casuriaga, Adriana Geisinger and José Sotelo-Silveira Tags: Research Source Type: research

Elucidation of the genetic determination of body weight and size in Chinese local chicken breeds by large-scale genomic analyses
Body weight and size are important economic traits in chickens. While many growth-related quantitative trait loci (QTLs) and candidate genes have been identified, further research is needed to confirm and char... (Source: BMC Genomics)
Source: BMC Genomics - March 20, 2024 Category: Genetics & Stem Cells Authors: Jie Wang, Jie Liu, Qiuxia Lei, Zhihe Liu, Haixia Han, Shuer Zhang, Chao Qi, Wei Liu, Dapeng Li, Fuwei Li, Dingguo Cao and Yan Zhou Tags: Research Source Type: research

Genome sequencing and analysis of black flounder (Paralichthys orbignyanus) reveals new insights into Pleuronectiformes genomic size and structure
Black flounder (Paralichthys orbignyanus, Pleuronectiformes) is a commercially significant marine fish with promising aquaculture potential in Argentina. Despite extensive studies on Black flounder aquaculture, i... (Source: BMC Genomics)
Source: BMC Genomics - March 20, 2024 Category: Genetics & Stem Cells Authors: Fernando Villarreal, Germ án F. Burguener, Ezequiel J. Sosa, Nicolas Stocchi, Gustavo M. Somoza, Adrián G. Turjanski, Andrés Blanco, Jordi Viñas and Alejandro S. Mechaly Tags: Research Source Type: research

Comparative mitogenomic analysis of subterranean and surface amphipods (Crustacea, Amphipoda) with special reference to the family Crangonyctidae
Mitochondrial genomes play important roles in studying genome evolution, phylogenetic analyses, and species identification. Amphipods (Class Malacostraca, Order Amphipoda) are one of the most ecologically dive... (Source: BMC Genomics)
Source: BMC Genomics - March 20, 2024 Category: Genetics & Stem Cells Authors: Joseph B. Benito, Megan L. Porter and Matthew L. Niemiller Tags: Research Source Type: research

Chromosome-level genome assembly provides insights into the genome evolution and functional importance of the phenylpropanoid –flavonoid pathway in Thymus mongolicus
Thymus mongolicus (family Lamiaceae) is a Thyme subshrub with strong aroma and remarkable environmental adaptability. Limited genomic information limits the use of this plant. (Source: BMC Genomics)
Source: BMC Genomics - March 19, 2024 Category: Genetics & Stem Cells Authors: Zhenhua Dang, Ying Xu, Xin Zhang, Wentao Mi, Yuan Chi, Yunyun Tian, Yaling Liu and Weibo Ren Tags: Research Source Type: research

Comprehensive analysis of genomic complexity in the 5 ’ end coding region of the DMD gene in patients of exons 1–2 duplications based on long-read sequencing
Dystrophinopathies are the most common X-linked inherited muscle diseases, and the disease-causing gene is DMD. Exonic duplications are a common type of pathogenic variants in the DMD gene, however, 5 ’ end exonic... (Source: BMC Genomics)
Source: BMC Genomics - March 19, 2024 Category: Genetics & Stem Cells Authors: Jiandong Shen, Taoli Ding, Xueping Sun, Ji Yang, Yue Zhang, Jing Wang, Mengdi Ge, Heng Xu, Jiazi Xie, Fei Wang and Feiyang Diao Tags: Research Source Type: research

RNA-binding proteins potentially regulate the alternative splicing of apoptotic genes during knee osteoarthritis progression
Alternative splicing (AS) is a principal mode of genetic regulation and one of the most widely used mechanisms to generate structurally and functionally distinct mRNA and protein variants. Dysregulation of AS ... (Source: BMC Genomics)
Source: BMC Genomics - March 19, 2024 Category: Genetics & Stem Cells Authors: Zheng Zhang, Limei Dong, Hai Tao, Yusong Dong, Wei Xiang, Fenghua Tao and Yingchun Zhao Tags: Research Source Type: research

Antimicrobial resistance and heterogeneity of Neisseria gonorrhoeae isolated from patients attending sexually transmitted infection clinics in Lusaka, Zambia
Antimicrobial resistance (AMR) of Neisseria gonorrhoeae is a threat to public health as strains have developed resistance to antimicrobials available for the treatment of gonorrhea. Whole genome sequencing (WGS) ... (Source: BMC Genomics)
Source: BMC Genomics - March 18, 2024 Category: Genetics & Stem Cells Authors: Kelvin Lutambo Sarenje, Marco van Zwetselaar, Happiness Kumburu, Tolbert Sonda, Blandina Mmbaga, Owen Ngalamika, Margaret C. Maimbolwa, Amon Siame, Sody Munsaka and Geoffrey Kwenda Tags: Research Source Type: research