Early Peanut Introduction and Sources of Information amongst Parent/Caregivers
The NIAID Peanut Prevention Guidelines provide new conceptual ideas to feeding young infants. Focus Groups (FG) were utilized to describe what sources of information were influencing peanut introduction practices. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Waheeda Samady, Hodan Jibrell, Madeleine Davison, Corwin Rolling, Ruchi Gupta Source Type: research
The Temporal Trends of Peanut Anaphylaxis Rates in a Pediatric Emergency Department in Montreal, Canada, Following Early Peanut Introduction Guidelines
A recent Australian cohort suggests a slowing in year-over-year increases in food anaphylaxis, which coincides with updated early food introduction guidelines. We aim to determine the impact of the 2017 Addendum Guidelines for the Prevention of Peanut Allergy on the Canadian pediatric population. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Derek Lanoue, Joshua Yu, Adhora Mir, Mohammed Kaouache, Adam Bretholz, Ann Clarke, Christine McCusker, Jennifer Protudjer, Moshe Ben-Shoshan Source Type: research
Food Allergy Documentation Patterns in Children in the Era of Early Food Introduction
The 2015 Learning Early About Peanut Allergy (LEAP) study motivated the publication of multi-organization consensus statements (PMID 26300927) supporting early peanut introduction in children at high-risk for IgE-mediated food allergy (IgE-FA). The effect of the early food introduction paradigm shift on IgE-FA epidemiology is unknown. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Stanislaw Gabryszewski, Jesse Dudley, Robert Grundmeier, Alexander Fiks, Jonathan Spergel, David Hill Source Type: research
Association of Household Egg Consumption and Development of Egg Allergy in Children with Atopic Dermatitis
This study seeks to investigate the correlation between household egg exposure and the risk of egg sensitization or egg allergy in patients with atopic dermatitis (AD). (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Suravat Homvises, Onnicha Chaiseksamphan, Pantipa Chatchatee, Wanlapa Weerapakorn, Natsaran Meprayoonwong, Jarungchit Ngamphaiboon, Rapisa Nantanee, Pannipa Kittipongpattana, Narissara Suratannon Source Type: research
Incidence of sunflower seed allergy in a pediatric allergy clinic
Sunflower seeds are a popular peanut alternative. We sought to describe sunflower seed allergy incidence and sunflower seed product sales. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Elsa Treffeisen, Claire Mepyans, Ellen Conroy, Joshua Petimar, Heather Baer, David Williams, Kathryn Williams, Lynda Schneider Source Type: research
Skin Prick Test Using Autoclaved Peanut Extract Results in Decreased Wheal Sizes and is Associated with Lower Peanut-Specific IgE Levels in Allergic Patients
Peanut oral immunotherapy (OIT) is commonly achieved using crushed raw or roasted peanut, though adverse reactions throughout treatment are frequent. High-pressure and temperature autoclaving has been shown to alter overall protein secondary structure and decrease in vitro binding of peanut-specific immunoglobulin E (sIgE). We aimed to assess clinical responses to the autoclaved peanut. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Casey Cohen, Diana Toscano Rivero, Eisha Ahmed, Wei Zhao, Danbing Ke, Duncan Lejtenyi, Liane Beaudette, Bertrand Jean-Claude, Moshe Ben-Shoshan, Bruce Mazer Source Type: research
Longitudinal peanut and Ara h 2 specific-IgE, -IgG4 and -IgG4/-IgE ratios are associated with the natural resolution of peanut allergy in childhood
Reports on the natural history of challenge-confirmed peanut allergy using prospective, population-based cohorts are rare. Little is known if specific-IgE (sIgE) or specific-IgG4 (sIgG4) to whole peanut or component Ara h 2 are useful biomarkers for identifying naturally resolving peanut allergy. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Kayla Parker, Rushani Wijesuriya, Thanh Dang, Victoria Soriano, Adrian Lowe, Shyamali Dharmage, Paxton Loke, Jennifer Koplin, Kirsten Perrett, Rachel Peters Source Type: research
Characterization of peanut sensitization and outcome of oral food challenge and increase of AD in patients 1-year-old or younger
The CSACI advises early peanut introduction at 6mo, including infants with atopic dermatitis (IAD). The NIAID relies on eczema severity to determine if formal allergy evaluation is encouraged before peanut exposure. A community based practice reviewed outcomes of both approaches and results of In-Clinic Oral Challenges (ICOC) and Home-Oral Food Challenges (HOFC). (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Kyla Leong-Poi, Jason Ohayon Source Type: research
Peanut Diagnostics In Predicting Oral Challenge Outcome: One Academic Center's Experience
This study adds to the literature the value of using peanut diagnostic cutoff values in selecting patients for food challenges. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Andrew Van Hersh, Devki Kothari, Renu Bansal, Le Kang, Santhosh Kumar Source Type: research
Interplay of Walnut and Peanut Allergies in Pediatric Anaphylaxis: Prevalence, Cross-Reactivity, and Therapeutic Implications
This study examines its risk in a large food anaphylactic pediatric cohort enrolled in the Tolerance Induction Program (TIPTM). The evolutionary conservation between peanut and walnut proteins and the clinical observations indicating those with peanut allergy are at increased risk for walnut allergy underscores the potential utility of walnuts in advancing biosimilar protein immunotherapy. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Diana Fregoso, Inderpal Randhawa, Nathan Marsteller Source Type: research
Comprehensive murine model of IgE mediated multiple food-group cross-reactive anaphylaxis
Approximately 32 million people in the US suffer from food allergies. Clinically, peanut/tree nuts, fish and shellfish food groups have substantial risk of cross reactivity. A murine model of multiple food group-cross reactivity is needed for developing novel therapies. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Fariba Ardalani, Ibrahim Musa, Nan Yang, Xiu-Min Li Source Type: research
Characteristics Leading to Mechanical Ventilation in Children Admitted for First Episode of Anaphylaxis due to Peanuts
Peanut allergy is an increasingly prevalent problem, leading to an escalation in hospitalization rates. However, severe reactions necessitating mechanical ventilation remain rare. We aim to identify the characteristics leading mechanical ventilation in children admitted for the first episode of anaphylaxis due to peanuts. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Rajan Chamlagain, Kamleshun Ramphul, Sophia Hernandez, Briana Hernandez, Shruti Aggarwal, Hemamalini Sakthivel, Adil Khan, David Kaufman Source Type: research
Survey of Arkansas Pediatric Providers on the Application of the NIH/NIAID Addendum Guidelines for the Prevention of Peanut Allergy in the United States
Following publication of the 2017 NIH/NIAID Guidelines for the Prevention of Peanut Allergy, the Arkansas Children ’s Allergy Clinic has maintained high referral volumes for peanut allergy and low referral volumes for early peanut introduction in high-risk infants. We aim to identify barriers and develop strategies to assist Arkansas pediatric providers with effective, evidence-based guidelines implementation. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Callie Margiotta, Emily Seminara, Robbie Pesek, Joshua Kennedy, Akilah Jefferson, Peggy Chandler, Anne Hiegel, Tamara Perry, Amy Scurlock, Stacie Jones Source Type: research
Motivations and Considerations for Families Pursuing Peanut Oral Immunotherapy
The unpredictable nature of unintentional exposures to food allergens and the potential for anaphylaxis, which may be life-threatening, negatively impacts quality of life for patients with food allergies and their families. Oral immunotherapy (OIT) is becoming more mainstream as an adjunctive treatment to strict avoidance but increases the risk of allergic reactions. Improved understanding of why families pursue OIT may advance management of food allergy. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Jennifer Li, Chen Rosenberg Source Type: research
Real World Adoption of Infant Peanut Oral Immunotherapy
Peanut oral immunotherapy (POIT) in children (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Allison Ramsey, Linh-An Tuong, Peter Capucilli, Denise Sanchez Tejera, S. Shahzad Mustafa Source Type: research
