Early solid introduction to prevent IgE-mediated food allergy should continue unabated while we learn more about FPIES prevalence

Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated allergy that typically presents in infancy with introduction of infant formula or solid foods. While previously thought to be rare, recent studies have reported a notable increase in prevalence, particularly among peanut and egg (Table 1). FPIES to peanut has historically been uncommon. Interestingly, several case series have described increased incidence of peanut FPIES in recent years and cited the 2015 Learning Early about Peanut Allergy (LEAP) study as a potential driving factor.

Source: Annals of Allergy, Asthma and Immunology - February 16, 2024 Category: Allergy & Immunology Authors: Linlei Ye, Stephanie C. Erdle, Elissa M. Abrams, Edmond S. Chan Tags: Perspective Source Type: research