Type 2 diabetes is associated with the accumulation of senescent T cells.
This article is protected by copyright. All rights reserved. PMID: 31251396 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - June 28, 2019 Category: Allergy & Immunology Authors: Lau EY, Carroll EC, Callender LA, Hood GA, Berryman V, Pattrick M, Finer S, Hitman GA, Ackland GL, Henson SM Tags: Clin Exp Immunol Source Type: research

Interstitial lung disease in patients with Common Variable Immunodeficiency Disorders: several different pathologies?
This article is protected by copyright. All rights reserved. PMID: 31216049 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - June 19, 2019 Category: Allergy & Immunology Authors: Patel S, Anzilotti C, Lucas M, Moore N, Chapel H Tags: Clin Exp Immunol Source Type: research

T- Cell Functionality in HIV-1, HIV-2 and Dually Infected Individuals: Correlates of Disease Progression and Immune Restoration.
This article is protected by copyright. All rights reserved. PMID: 31216050 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - June 19, 2019 Category: Allergy & Immunology Authors: Salwe SS, Padwal V, Nagar V, Patil P, Patel V Tags: Clin Exp Immunol Source Type: research

Decreased A20 expression on circulating CD56bright NK cells contributes to a worse disease status in patients with ankylosing spondylitis.
This article is protected by copyright. All rights reserved. PMID: 31206174 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - June 17, 2019 Category: Allergy & Immunology Authors: Yang M, Zhou Y, Liu L, Wang S, Jiang J, Shang Q, Yu H, Xiang X, Pang X, Li T, Zhao P Tags: Clin Exp Immunol Source Type: research

TNF-derived peptides inhibit tumour growth and metastasis through cytolytic effects on tumour lymphatics.
This article is protected by copyright. All rights reserved. PMID: 31206614 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - June 17, 2019 Category: Allergy & Immunology Authors: Lu W, Wang Y, Zhang Q, Owen S, Green M, Ni T, Edwards M, Li Y, Zhang L, Harris A, Li JL, Jackson DG, Jiang S Tags: Clin Exp Immunol Source Type: research

Experimental colitis in IL-10-deficient mice ameliorates in the absence of PTPN22.
This article is protected by copyright. All rights reserved. PMID: 31194881 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - June 13, 2019 Category: Allergy & Immunology Authors: Jofra T, Galvani G, Cosorich I, De Giorgi L, Annoni A, Vecchione A, Sorini C, Falcone M, Fousteri G Tags: Clin Exp Immunol Source Type: research

Regulatory T cells: exploring mechanisms for future therapies.
This article is protected by copyright. All rights reserved. PMID: 31177531 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - June 8, 2019 Category: Allergy & Immunology Authors: Piccirillo CA Tags: Clin Exp Immunol Source Type: research

Interleukin-17 and Interleukin-22 synergy linking inflammation and EMT- dependent fibrosis in Sj ögren's syndrome.
This article is protected by copyright. All rights reserved. PMID: 31165469 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - June 5, 2019 Category: Allergy & Immunology Authors: Sisto M, Lorusso L, Tamma R, Ingravallo G, Ribatti D, Lisi S Tags: Clin Exp Immunol Source Type: research

Acquired immune responses to the seasonal trivalent influenza vaccination in COPD.
This article is protected by copyright. All rights reserved. PMID: 31161649 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - June 4, 2019 Category: Allergy & Immunology Authors: Staples KJ, Williams NP, Bonduelle O, Hutton AJ, Cellura D, Marriott AC, Combadière B, Wilkinson TMA Tags: Clin Exp Immunol Source Type: research

HIPs and HIP-reactive T cells.
This article is protected by copyright. All rights reserved. PMID: 31132145 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - May 27, 2019 Category: Allergy & Immunology Authors: Wiles TA, Delong T Tags: Clin Exp Immunol Source Type: research

The immune system and psychiatric disease: a basic science perspective.
This article is protected by copyright. All rights reserved. PMID: 31125426 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - May 24, 2019 Category: Allergy & Immunology Authors: Bennett FC, Molofsky AV Tags: Clin Exp Immunol Source Type: research

Cytokine patterns in critically ill patients undergoing percutaneous tracheostomy.
In conclusion, in this standard human model of soft tissue injury, by applying longitudinal analysis at the individual level, we have been able to identify the cytokine patterns underlying the seemingly random, heterogeneous patient responses. We have also identified consistent cytokine interactions suggesting that IL6, GCSF, MCP1 and MIP1β are the cytokines most likely driving the immune response to this injury. This article is protected by copyright. All rights reserved. PMID: 31125429 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - May 24, 2019 Category: Allergy & Immunology Authors: Trahtemberg U, Bazak N, Sviri S, Beil M, Paschke S, van Heerden PV Tags: Clin Exp Immunol Source Type: research

Enhanced monocyte recruitment and delayed alternative macrophage polarisation accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice.
This article is protected by copyright. All rights reserved. PMID: 31119724 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - May 23, 2019 Category: Allergy & Immunology Authors: Toor IS, Rückerl D, Mair I, Thomson A, Rossi AG, Newby DE, Allen JE, Gray GA Tags: Clin Exp Immunol Source Type: research

Influence of maternal microbiota during pregnancy on infant immunity.
This article is protected by copyright. All rights reserved. PMID: 31121057 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - May 23, 2019 Category: Allergy & Immunology Authors: Nyangahu DD, Jaspan HB Tags: Clin Exp Immunol Source Type: research

A study of 51 subtypes of peripheral blood immune cells in newly diagnosed young type 1 diabetes patients.
This article is protected by copyright. All rights reserved. PMID: 31116879 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - May 22, 2019 Category: Allergy & Immunology Authors: Oras A, Peet A, Giese T, Tillmann V, Uibo R Tags: Clin Exp Immunol Source Type: research

Metabolism at the centre of the host-microbe relationship.
This article is protected by copyright. All rights reserved. PMID: 31107965 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - May 20, 2019 Category: Allergy & Immunology Authors: Maslowski KM Tags: Clin Exp Immunol Source Type: research

Circulating lectin pathway proteins do not predict short-term cardiac outcomes after myocardial infarction.
Bjerre M Abstract In spite of improvements in treatment, coronary artery disease is still responsible for one third of all deaths globally, predominantly due to myocardial infarction (MI) and stroke. There is an important potential in developing new strategies for treatment of patients with these conditions. Inflammation, and in particular the actions of the complement system, has emerged as part of the pathogenesis in the reperfusion injury in patients with MI. To further qualify this, we examined the association between the plasma levels of lectin pathway proteins and myocardial endpoints; left ventricular ejec...
Source: Clinical and Developmental Immunology - May 18, 2019 Category: Allergy & Immunology Authors: Brinck Holt C, Østergaard JA, Thiel S, Hansen TK, Mellbin L, Sörensson P, Bjerre M Tags: Clin Exp Immunol Source Type: research

IL-17 and TNF α cooperation contributes to the pro-inflammatory response of hepatic stellate cells.
This article is protected by copyright. All rights reserved. PMID: 31102558 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - May 18, 2019 Category: Allergy & Immunology Authors: Beringer A, Miossec P Tags: Clin Exp Immunol Source Type: research

IL-1 Receptor Antagonist, Anakinra, Prevents Myocardial Dysfunction in a Mouse Model of Kawasaki Disease Vasculitis and Myocarditis.
This article is protected by copyright. All rights reserved. PMID: 31099056 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - May 17, 2019 Category: Allergy & Immunology Authors: Gorelik M, Lee Y, Abe M, Andrews T, Davis L, Patterson J, Chen S, Crother TR, Aune GJ, Noval Rivas M, Arditi M Tags: Clin Exp Immunol Source Type: research

Neutrophils develop rapid proinflammatory response after engulfing Hb-activated platelets under intravascular hemolysis.
This article is protected by copyright. All rights reserved. PMID: 31099890 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - May 17, 2019 Category: Allergy & Immunology Authors: Bhasym A, Annarapu GK, Saha S, Shrimali N, Gupta S, Seth T, Guchhait P Tags: Clin Exp Immunol Source Type: research

Mitigating placental injuries through up-regulating DAF in experimental APS mice:new mechanism of progesterone.
This article is protected by copyright. All rights reserved. PMID: 31091357 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - May 15, 2019 Category: Allergy & Immunology Authors: Zhang Y, Jin S Tags: Clin Exp Immunol Source Type: research

Overview of procalcitonin in pregnancy and in pre-eclampsia.
Abstract Procalcitonin (PCT), a precursor for calcitonin, is a pro-hormone involved in the inflammatory processes, which has been poorly studied in the context of pregnancy. During severe inflammation, PCT derives from almost all cell types, including monocytes and parenchymal tissues, making it as a good predictive and diagnostic marker of an inflammatory state with rapidly increased serum levels in inflammation or sepsis. PMID: 31081935 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - May 13, 2019 Category: Allergy & Immunology Authors: Mangogna A, Agostinis C, Ricci G, Romano F, Bulla R Tags: Clin Exp Immunol Source Type: research

MicroRNA-466a-3p attenuates allergic nasal inflammation in mice by targeting GATA3.
Abstract Allergic rhinitis is thought to be an allergic disease associated with IgE-mediated immune response, characterized by increased Th2 cytokine production, elevated eosinophil levels in the nasal mucosa and induced nasal secretions. MicroRNA microarray data revealed that the expression level of miR-466a-3p was significantly decreased. Notably, GATA3 was identified as one of its target genes through miRNA target prediction web tools. The expression levels of miR-466a-3p were altered by mimics and lentivirus both in vivo and in vitro, as similar to those of GATA3. Furthermore, the symptoms and histology of all...
Source: Clinical and Developmental Immunology - May 13, 2019 Category: Allergy & Immunology Authors: Chen Z, Deng Y, Li F, Xiao B, Zhou X, Tao Z Tags: Clin Exp Immunol Source Type: research

Disrupted regulation of serpinB9 in circulating T cells is associated with an increased risk for post-transplant skin cancer.
This article is protected by copyright. All rights reserved. PMID: 31059128 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - May 6, 2019 Category: Allergy & Immunology Authors: Peters FS, Peeters AM, van den Bosch TP, Mooyaart AL, van de Wetering J, Betjes MG, Baan CC, Boer K Tags: Clin Exp Immunol Source Type: research

Vaccines for emerging pathogens: from research to the clinic.
Abstract In this two-part series of reviews, we have invited experts in their fields to contribute articles on the status of vaccine research and development for emerging pathogens. This topic has been brought into sharp focus in recent years following significant outbreaks of viral diseases such as those causing severe acute respiratory syndrome and Middle East respiratory syndrome, as well as devastating outbreaks of diseases caused by the Ebola, Marburg, Zika and Lassa fever viruses, to name only a few examples. Additionally, bacterial infections leading to bubonic and pneumonic plague, most notably in Madagasc...
Source: Clinical and Developmental Immunology - April 19, 2019 Category: Allergy & Immunology Authors: Williamson ED Tags: Clin Exp Immunol Source Type: research

Emerging viruses and current strategies for vaccine intervention.
Abstract During the past decade several notable viruses have suddenly emerged from obscurity or anonymity to become serious global health threats, provoking concern regarding their sustained epidemic transmission in immunologically naive human populations. With each new threat comes the call for rapid vaccine development. Indeed, vaccines are considered a critical component of disease prevention for emerging viral infections because, in many cases, other medical options are limited or non-existent, or that infections result in such a rapid clinical deterioration that the effectiveness of therapeutics is limited. W...
Source: Clinical and Developmental Immunology - April 19, 2019 Category: Allergy & Immunology Authors: Afrough B, Dowall S, Hewson R Tags: Clin Exp Immunol Source Type: research

Use of bioengineered human commensal gut bacteria-derived microvesicles for mucosal plague vaccine delivery and immunization.
ng SR Abstract Plague caused by the Gram-negative bacterium, Yersinia pestis, is still endemic in parts of the world today. Protection against pneumonic plague is essential to prevent the development and spread of epidemics. Despite this, there are currently no licensed plague vaccines in the western world. Here we describe the means of delivering biologically active plague vaccine antigens directly to mucosal sites of plague infection using highly stable microvesicles (outer membrane vesicles; OMVs) that are naturally produced by the abundant and harmless human commensal gut bacterium Bacteroides thetaiotaomicron...
Source: Clinical and Developmental Immunology - April 15, 2019 Category: Allergy & Immunology Authors: Carvalho AL, Miquel-Clopés A, Wegmann U, Jones E, Stentz R, Telatin A, Walker NJ, Butcher WA, Brown PJ, Holmes S, Dennis MJ, Williamson ED, Funnell SGP, Stock M, Carding SR Tags: Clin Exp Immunol Source Type: research

Vaccines for emerging pathogens: prospects for licensure.
Abstract Globally, there are a number of emerging pathogens. For most, there are no licensed vaccines available for human use, although there is ongoing research and development. However, given the extensive and increasing list of emerging pathogens and the investment required to bring vaccines into clinical use, the task is huge. Overlaid on this task is the risk of anti-microbial resistance (AMR) acquisition by micro-organisms which can endow a relatively harmless organism with pathogenic potential. Furthermore, climate change also introduces a challenge by causing some of the insect vectors and environmental co...
Source: Clinical and Developmental Immunology - April 11, 2019 Category: Allergy & Immunology Authors: Williamson ED, Westlake GE Tags: Clin Exp Immunol Source Type: research

HLA-E: exploiting pathogen-host interactions for vaccine development.
Abstract Viruses, when used as vectors for vaccine antigen delivery, can induce strong cellular and humoral responses against target epitopes. Recent work by Hansen et al. describes the use of a cytomegalovirus-vectored vaccine, which is able to generate a stable effector-memory T cell population at the sites of vaccination in rhesus macaques. This vaccine, targeted towards multiple epitopes in simian immunodeficiency virus (SIV), did not induce classical CD8+ T cells. However, non-canonical CD8+ T cell induction occurred via major histocompatibility complex (MHC) class II and MHC-E. The MHC-E-restricted T cells c...
Source: Clinical and Developmental Immunology - April 9, 2019 Category: Allergy & Immunology Authors: Sharpe HR, Bowyer G, Brackenridge S, Lambe T Tags: Clin Exp Immunol Source Type: research

Mucosal vaccines and technology.
ng SR Abstract There is an urgent and unmet need to develop effective vaccines to reduce the global burden of infectious disease in both animals and humans, and in particular for the majority of pathogens that infect via mucosal sites. Here we summarise the impediments to developing mucosal vaccines and review the new and emerging technologies aimed at overcoming the lack of effective vaccine delivery systems that is the major obstacle to developing new mucosal vaccines. PMID: 30963541 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - April 8, 2019 Category: Allergy & Immunology Authors: Miquel-Clopés A, Bentley EG, Stewart JP, Carding SR Tags: Clin Exp Immunol Source Type: research

Novel approaches for the design, delivery and administration of vaccine technologies.
Abstract It is easy to argue that vaccine development represents humankind's most important and successful endeavour, such is the impact that vaccination has had on human morbidity and mortality over the last 200 years. During this time the original method of Jenner and Pasteur, i.e. that of injecting live-attenuated or inactivated pathogens, has been developed and supplemented with a wide range of alternative approaches which are now in clinical use or under development. These next-generation technologies have been designed to produce a vaccine that has the effectiveness of the original live-attenuated and i...
Source: Clinical and Developmental Immunology - April 8, 2019 Category: Allergy & Immunology Authors: Wallis J, Shenton DP, Carlisle RC Tags: Clin Exp Immunol Source Type: research

Novel multi-component vaccine approaches for Burkholderia pseudomallei.
Abstract Burkholderia pseudomallei is the causative agent of melioidosis. Historically believed to be a relatively rare human disease in tropical countries, a recent study estimated that, worldwide, there are approximately 165 000 human melioidosis cases per year, more than half of whom die. The bacterium is inherently resistant to many antibiotics and treatment of the disease is often protracted and ineffective. There is no licensed vaccine against melioidosis, but a vaccine is predicted to be of value if used in high-risk populations. There has been progress over the last decade in the pursuit of an effecti...
Source: Clinical and Developmental Immunology - April 8, 2019 Category: Allergy & Immunology Authors: Morici L, Torres AG, Titball RW Tags: Clin Exp Immunol Source Type: research

Relation of HLA-DRB1 to IgG4 autoantibody and cytokine production in muscle-specific tyrosine kinase myasthenia gravis (MuSK-MG).
This article is protected by copyright. All rights reserved. PMID: 30929252 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 31, 2019 Category: Allergy & Immunology Authors: Çebi M, Durmuş H, Yılmaz V, Yentür SP, Aysal F, Oflazer P, Parman Y, Deymeer F, Saruhan-Direskeneli G Tags: Clin Exp Immunol Source Type: research

Regulatory T cell features in Chronic Granulomatous Disease.
This article is protected by copyright. All rights reserved. PMID: 30924925 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 29, 2019 Category: Allergy & Immunology Authors: van de Geer A, Cuadrado E, Slot MC, van Bruggen R, Amsen D, Kuijpers TW Tags: Clin Exp Immunol Source Type: research

High Fructose Induced Metabolic Changes Enhance Inflammation in Human Dendritic Cells.
This article is protected by copyright. All rights reserved. PMID: 30919933 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 28, 2019 Category: Allergy & Immunology Authors: Jaiswal N, Agrawal S, Agrawal A Tags: Clin Exp Immunol Source Type: research

Identification of susceptibility SNPs in CTLA4 and PTPN22 for scleritis in Han Chinese.
In conclusions, our findings indicate that CTLA4 and PTPN22 might confer genetic susceptibility to scleritis in a Chinese Han population. This article is protected by copyright. All rights reserved. PMID: 30921471 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 28, 2019 Category: Allergy & Immunology Authors: Li F, Ma X, Du L, Shi L, Cao Q, Li N, Pang T, Liu Y, Kijlstra A, Yang P Tags: Clin Exp Immunol Source Type: research

Tissue Talks: Immunophenotype of Cells Infiltrating the Graft Explains Histological Findings and the Benefits of Belatacept at 10 years.
This article is protected by copyright. All rights reserved. PMID: 30916387 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 27, 2019 Category: Allergy & Immunology Authors: Furuzawa-Carballeda J, Uribe-Uribe NO, Arreola-Guerra JM, Reyes-Acevedo R, Vilatobá M, López-Toledo A, Mondragón-Salgado G, Chávez-Fernández R, López-Verdugo F, Mondragón-Ramírez G, Alberú J Tags: Clin Exp Immunol Source Type: research

Methods to manufacture regulatory T cells for cell therapy.
This article is protected by copyright. All rights reserved. PMID: 30913302 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 26, 2019 Category: Allergy & Immunology Authors: MacDonald KN, Piret JM, Levings MK Tags: Clin Exp Immunol Source Type: research

Distinct patterns of na ïve, activated and memory T and B cells in blood of patients with ulcerative colitis or Crohn's disease.
This article is protected by copyright. All rights reserved. PMID: 30883691 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 18, 2019 Category: Allergy & Immunology Authors: Rabe H, Malmquist M, Barkman C, Östman S, Gjertsson I, Saalman R, Wold AE Tags: Clin Exp Immunol Source Type: research

Sculpting tumor microenvironment with immune system: from immunometabolism to immunoediting.
This article is protected by copyright. All rights reserved. PMID: 30873592 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 15, 2019 Category: Allergy & Immunology Authors: Yu YR, Ho PC Tags: Clin Exp Immunol Source Type: research

Sensing between reactions - how the metabolic microenvironment shapes immunity.
This article is protected by copyright. All rights reserved. PMID: 30868561 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 13, 2019 Category: Allergy & Immunology Authors: Lötscher J, Balmer ML Tags: Clin Exp Immunol Source Type: research

Mechanisms of human Foxp3+ Treg cell development and function in health and disease.
This article is protected by copyright. All rights reserved. PMID: 30864147 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 12, 2019 Category: Allergy & Immunology Authors: Attias M, Al-Aubodah TA, Piccirillo CA Tags: Clin Exp Immunol Source Type: research

Cellular immunological changes in patients with LADA are a mixture of those seen in patients with type 1 and type 2 diabetes.
CONCLUSION: LADA presents a mixed cellular immunological pattern with features overlapping with both T1D and T2D. This article is protected by copyright. All rights reserved. PMID: 30843600 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 7, 2019 Category: Allergy & Immunology Authors: Singh K, Martinell M, Luo Z, Espes D, Stålhammar J, Sandler S, Carlsson PO Tags: Clin Exp Immunol Source Type: research

The role of FOXP3+ regulatory T cells in human autoimmune and inflammatory diseases.
This article is protected by copyright. All rights reserved. PMID: 30830965 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 4, 2019 Category: Allergy & Immunology Authors: Mohr A, Atif M, Balderas R, Gorochov G, Miyara M Tags: Clin Exp Immunol Source Type: research

Prognostic biomarkers for immunotherapy with ipilimumab in metastatic melanoma.
This article is protected by copyright. All rights reserved. PMID: 30821848 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - March 1, 2019 Category: Allergy & Immunology Authors: Nyakas M, Aamdal E, Jacobsen KD, Guren TK, Aamdal S, Hagene KT, Brunsvig P, Yndestad A, Halvorsen B, Tasken KA, Aukrust P, Maelandsmo GM, Ueland T Tags: Clin Exp Immunol Source Type: research

Streptococcal superantigen-induced expansion of human tonsil T cells leads to altered T follicular helper cell phenotype, B cell death, and reduced immunoglobulin release.
CONCLUSIONS: SpeA and other superantigens cause dysregulated tonsil immune function, driving T cells from Tfh to a proliferating phenotype, with resultant loss of B cells and immunoglobulin production, providing superantigen-producing bacteria with a likely survival advantage. This article is protected by copyright. All rights reserved. PMID: 30815853 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - February 27, 2019 Category: Allergy & Immunology Authors: Davies FJ, Olme C, Lynskey NN, Turner CE, Sriskandan S Tags: Clin Exp Immunol Source Type: research

Expression and Function of Macrophage-Inducible C-type Lectin (Mincle) in Inflammation Driven Parturition in Fetal Membranes and Myometrium.
This article is protected by copyright. All rights reserved. PMID: 30793298 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - February 21, 2019 Category: Allergy & Immunology Authors: Lim R, Lappas M Tags: Clin Exp Immunol Source Type: research

Delayed disease progression in HIV-2: The importance of TRIM5 α and the retroviral capsid.
This article is protected by copyright. All rights reserved. PMID: 30773620 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - February 17, 2019 Category: Allergy & Immunology Authors: Boswell MT, Rowland-Jones S Tags: Clin Exp Immunol Source Type: research

The role of neutrophil activation in determining the outcome of pregnancy and modulation by hormones and/or cytokines.
This article is protected by copyright. All rights reserved. PMID: 30768780 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - February 15, 2019 Category: Allergy & Immunology Authors: Hahn S, Hasler P, Vokalova L, van Breda SV, Lapaire O, Than GN, Hoesli I, Rossi SW Tags: Clin Exp Immunol Source Type: research

Neuroimmunology - The Past, Present and Future.
This article is protected by copyright. All rights reserved. PMID: 30768789 [PubMed - as supplied by publisher] (Source: Clinical and Developmental Immunology)
Source: Clinical and Developmental Immunology - February 15, 2019 Category: Allergy & Immunology Authors: Nutma E, Willison H, Gianvito M, Amor S Tags: Clin Exp Immunol Source Type: research