Evaluation of Moringa Oleifera Leaf Extract for its In vitro Antibacterial Properties, Mechanism of Action, and In vivo Corneal Ulcer Healing Effects in Rabbits' Eyes
Curr Drug Deliv. 2024 Apr 17. doi: 10.2174/0115672018275561240228065755. Online ahead of print.ABSTRACTM. oleifera is the most adapted tree species in different medicinal eco-systems and has resilience against climate changes. This multiple-use tree provides healthy foods, snacks, honey, and fuel. Besides this, it has immense promising applicationsby offering antimicrobial and antibacterial activities for targeted uses. This validates the court of Hippocrates that let food be the medicine and medicine be the food for which moringa qualifies. In view of this, the antioxidant and in vitro antibacterial potency of the hydro-e...
Source: Current Drug Delivery - April 19, 2024 Category: Drugs & Pharmacology Authors: Ayesha Bibi Meenakshi Dhanawat Shahbaz Aman Samrat Chauhan Rishabh Chalotra Somdutt Mujwar Narinder Kaur ChamasseHomary Maivagna Sumeet Gupta Source Type: research
Managing Antimicrobial Resistance in the Emergency Department
Emerg Med Clin North Am. 2024 May;42(2):461-483. doi: 10.1016/j.emc.2024.02.005. Epub 2024 Mar 15.ABSTRACT(Basic awareness and understanding of antimicrobial resistance and prevailing mechanisms can aid emergency physicians in providing appropriate care to patients with infections due to a multidrug-resistant organism (MDRO). Empiric treatment of MDRO infections should be approached with caution and guided by the most likely pathogens based on differential diagnosis, severity of the illness, suspected source of infection, patient-specific factors, and local antibiotic susceptibility patterns. Newer broad-spectrum antibioti...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Julianne Yeary Larissa Hacker Stephen Y Liang Source Type: research
Evaluation of Moringa Oleifera Leaf Extract for its In vitro Antibacterial Properties, Mechanism of Action, and In vivo Corneal Ulcer Healing Effects in Rabbits' Eyes
Curr Drug Deliv. 2024 Apr 17. doi: 10.2174/0115672018275561240228065755. Online ahead of print.ABSTRACTM. oleifera is the most adapted tree species in different medicinal eco-systems and has resilience against climate changes. This multiple-use tree provides healthy foods, snacks, honey, and fuel. Besides this, it has immense promising applicationsby offering antimicrobial and antibacterial activities for targeted uses. This validates the court of Hippocrates that let food be the medicine and medicine be the food for which moringa qualifies. In view of this, the antioxidant and in vitro antibacterial potency of the hydro-e...
Source: Current Drug Delivery - April 19, 2024 Category: Drugs & Pharmacology Authors: Ayesha Bibi Meenakshi Dhanawat Shahbaz Aman Samrat Chauhan Rishabh Chalotra Somdutt Mujwar Narinder Kaur ChamasseHomary Maivagna Sumeet Gupta Source Type: research
Managing Antimicrobial Resistance in the Emergency Department
Emerg Med Clin North Am. 2024 May;42(2):461-483. doi: 10.1016/j.emc.2024.02.005. Epub 2024 Mar 15.ABSTRACT(Basic awareness and understanding of antimicrobial resistance and prevailing mechanisms can aid emergency physicians in providing appropriate care to patients with infections due to a multidrug-resistant organism (MDRO). Empiric treatment of MDRO infections should be approached with caution and guided by the most likely pathogens based on differential diagnosis, severity of the illness, suspected source of infection, patient-specific factors, and local antibiotic susceptibility patterns. Newer broad-spectrum antibioti...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Julianne Yeary Larissa Hacker Stephen Y Liang Source Type: research
Evaluation of Moringa Oleifera Leaf Extract for its In vitro Antibacterial Properties, Mechanism of Action, and In vivo Corneal Ulcer Healing Effects in Rabbits' Eyes
Curr Drug Deliv. 2024 Apr 17. doi: 10.2174/0115672018275561240228065755. Online ahead of print.ABSTRACTM. oleifera is the most adapted tree species in different medicinal eco-systems and has resilience against climate changes. This multiple-use tree provides healthy foods, snacks, honey, and fuel. Besides this, it has immense promising applicationsby offering antimicrobial and antibacterial activities for targeted uses. This validates the court of Hippocrates that let food be the medicine and medicine be the food for which moringa qualifies. In view of this, the antioxidant and in vitro antibacterial potency of the hydro-e...
Source: Current Drug Delivery - April 19, 2024 Category: Drugs & Pharmacology Authors: Ayesha Bibi Meenakshi Dhanawat Shahbaz Aman Samrat Chauhan Rishabh Chalotra Somdutt Mujwar Narinder Kaur ChamasseHomary Maivagna Sumeet Gupta Source Type: research
Managing Antimicrobial Resistance in the Emergency Department
Emerg Med Clin North Am. 2024 May;42(2):461-483. doi: 10.1016/j.emc.2024.02.005. Epub 2024 Mar 15.ABSTRACT(Basic awareness and understanding of antimicrobial resistance and prevailing mechanisms can aid emergency physicians in providing appropriate care to patients with infections due to a multidrug-resistant organism (MDRO). Empiric treatment of MDRO infections should be approached with caution and guided by the most likely pathogens based on differential diagnosis, severity of the illness, suspected source of infection, patient-specific factors, and local antibiotic susceptibility patterns. Newer broad-spectrum antibioti...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Julianne Yeary Larissa Hacker Stephen Y Liang Source Type: research
Evaluation of Moringa Oleifera Leaf Extract for its In vitro Antibacterial Properties, Mechanism of Action, and In vivo Corneal Ulcer Healing Effects in Rabbits' Eyes
Curr Drug Deliv. 2024 Apr 17. doi: 10.2174/0115672018275561240228065755. Online ahead of print.ABSTRACTM. oleifera is the most adapted tree species in different medicinal eco-systems and has resilience against climate changes. This multiple-use tree provides healthy foods, snacks, honey, and fuel. Besides this, it has immense promising applicationsby offering antimicrobial and antibacterial activities for targeted uses. This validates the court of Hippocrates that let food be the medicine and medicine be the food for which moringa qualifies. In view of this, the antioxidant and in vitro antibacterial potency of the hydro-e...
Source: Current Drug Delivery - April 19, 2024 Category: Drugs & Pharmacology Authors: Ayesha Bibi Meenakshi Dhanawat Shahbaz Aman Samrat Chauhan Rishabh Chalotra Somdutt Mujwar Narinder Kaur ChamasseHomary Maivagna Sumeet Gupta Source Type: research
Managing Antimicrobial Resistance in the Emergency Department
Emerg Med Clin North Am. 2024 May;42(2):461-483. doi: 10.1016/j.emc.2024.02.005. Epub 2024 Mar 15.ABSTRACT(Basic awareness and understanding of antimicrobial resistance and prevailing mechanisms can aid emergency physicians in providing appropriate care to patients with infections due to a multidrug-resistant organism (MDRO). Empiric treatment of MDRO infections should be approached with caution and guided by the most likely pathogens based on differential diagnosis, severity of the illness, suspected source of infection, patient-specific factors, and local antibiotic susceptibility patterns. Newer broad-spectrum antibioti...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Julianne Yeary Larissa Hacker Stephen Y Liang Source Type: research
Managing Antimicrobial Resistance in the Emergency Department
Emerg Med Clin North Am. 2024 May;42(2):461-483. doi: 10.1016/j.emc.2024.02.005. Epub 2024 Mar 15.ABSTRACT(Basic awareness and understanding of antimicrobial resistance and prevailing mechanisms can aid emergency physicians in providing appropriate care to patients with infections due to a multidrug-resistant organism (MDRO). Empiric treatment of MDRO infections should be approached with caution and guided by the most likely pathogens based on differential diagnosis, severity of the illness, suspected source of infection, patient-specific factors, and local antibiotic susceptibility patterns. Newer broad-spectrum antibioti...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Julianne Yeary Larissa Hacker Stephen Y Liang Source Type: research
Managing Antimicrobial Resistance in the Emergency Department
Emerg Med Clin North Am. 2024 May;42(2):461-483. doi: 10.1016/j.emc.2024.02.005. Epub 2024 Mar 15.ABSTRACT(Basic awareness and understanding of antimicrobial resistance and prevailing mechanisms can aid emergency physicians in providing appropriate care to patients with infections due to a multidrug-resistant organism (MDRO). Empiric treatment of MDRO infections should be approached with caution and guided by the most likely pathogens based on differential diagnosis, severity of the illness, suspected source of infection, patient-specific factors, and local antibiotic susceptibility patterns. Newer broad-spectrum antibioti...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Julianne Yeary Larissa Hacker Stephen Y Liang Source Type: research
Stewardship Prompts to Improve Antibiotic Selection for Pneumonia
This clinical trial examines the effect of an antibiotic stewardship bundle (education, feedback, and real-time multidrug-resistant organism risk-based CPOE prompts) vs routine stewardship on antibiotic selection during the first 3 hospital days in adults with pneumonia. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 19, 2024 Category: General Medicine Source Type: research
Stewardship Prompts to Improve Antibiotic Selection for Urinary Tract Infection
This clinical trial evaluates whether computerized provider order entry prompts providing patient- and pathogen-specific multidrug-resistant organism risk estimates could reduce use of empiric extended-spectrum antibiotics for treatment of urinary tract infections. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 19, 2024 Category: General Medicine Source Type: research
Severe cellulitis from methicillin-resistant Staphylococcus aureus (MRSA) in a couple of preterm twins: a case report
ConclusionsDue to the characteristic antibiotic resistance of MRSA and the potential complications of those infections in such delicate patients, basic prevention measures still represent the key to avoid the spreading of neonatal MRSA infections in NICUs, which include hand hygiene and strict precautions, as well as screening of patients for MRSA on admission and during hospital stay, routine prophylactic topical antibiotic of patients, enhanced environmental cleaning, cohorting and isolation of positive patients, barrier precautions, avoidance of ward crowding, and, in some units, surveillance, education and decolonizati...
Source: Italian Journal of Pediatrics - April 19, 2024 Category: Pediatrics Source Type: research
Oleanolic acid: an antimycobacterial component of < em > Syzygium aromaticum < /em > L. and inhibitor of efflux mediated drug resistance
Nat Prod Res. 2024 Apr 18:1-7. doi: 10.1080/14786419.2024.2343916. Online ahead of print.ABSTRACTOleanolic acid (OA) was isolated from Syzygium aromaticum L. buds, and structurally characterised using different spectroscopic techniques; MS, IR,1H/13C-NMR and 2D NMR experiments. The antimycobacterial activity according to a resazurin microtiter assay (REMA) showed important inhibitory effect of OA on the virulent H37Rv strain, with the lowest minimum concentration of 50 µg/mL, compared to other fractions. Molecular docking of OA with BacA drug efflux pump resulted in good binding affinity of hydrophobic interaction type. T...
Source: Natural Product Research - April 18, 2024 Category: Biochemistry Authors: Yassine El Ghallab Mohamed Dakir Achraf Aainouss My Driss El Messaoudi Sanae Derfoufi Source Type: research
Enterotoxigenic Staphylococcus aureus in Brazilian artisanal cheeses: Occurrence, counts, phenotypic and genotypic profiles
Food Microbiol. 2024 Aug;121:104531. doi: 10.1016/j.fm.2024.104531. Epub 2024 Apr 3.ABSTRACTThe present study aimed to assess the occurrence and counts of Staphylococcus aureus in Brazilian artisanal cheeses (BAC) produced in five regions of Brazil: Coalho and Manteiga (Northeast region); Colonial and Serrano (South); Caipira (Central-West); Marajó (North); and Minas Artisanal cheeses, from Araxá, Campos das Vertentes, Cerrado, Serro and Canastra microregions (Southeast). The resistance to chlorine-based sanitizers, ability to attach to stainless steel surfaces, and antibiogram profile of a large set of S. aureus strains...
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Larissa P Margalho Juliana S Gra ça Bruna A Kamimura Sarah H I Lee H éctor D S Canales Alexandra I A Chincha Magdevis Y R Caturla Ramon P Brex ó Aline Crucello Ver ônica O Alvarenga Adriano G Cruz Carlos Augusto F Oliveira Anderson S Sant'Ana Source Type: research
