Evaluation of Moringa Oleifera Leaf Extract for its In vitro Antibacterial Properties, Mechanism of Action, and In vivo Corneal Ulcer Healing Effects in Rabbits' Eyes
Curr Drug Deliv. 2024 Apr 17. doi: 10.2174/0115672018275561240228065755. Online ahead of print.ABSTRACTM. oleifera is the most adapted tree species in different medicinal eco-systems and has resilience against climate changes. This multiple-use tree provides healthy foods, snacks, honey, and fuel. Besides this, it has immense promising applicationsby offering antimicrobial and antibacterial activities for targeted uses. This validates the court of Hippocrates that let food be the medicine and medicine be the food for which moringa qualifies. In view of this, the antioxidant and in vitro antibacterial potency of the hydro-e...
Source: Current Drug Delivery - April 19, 2024 Category: Drugs & Pharmacology Authors: Ayesha Bibi Meenakshi Dhanawat Shahbaz Aman Samrat Chauhan Rishabh Chalotra Somdutt Mujwar Narinder Kaur ChamasseHomary Maivagna Sumeet Gupta Source Type: research
Gold Nanoparticle-Based Drug Delivery System for the Diagnosis and Treatment of Bacterial Meningitis
Curr Drug Deliv. 2024 Apr 16. doi: 10.2174/0115672018278607240405060054. Online ahead of print.ABSTRACTManaging bacterial pathogens in the central nervous system is an immense issue for researchers all around the globe. The problem of these infections remains throughout the population, regardless of the discovery of several possible medicines. The major obstacle to drug delivery is the BBB, but only a few medicines that fulfill demanding requirements can penetrate it. Considering inadequate antibiotic alternatives and the increasing development of resistance, it is more important than ever to find new approaches to address...
Source: Current Drug Delivery - April 17, 2024 Category: Drugs & Pharmacology Authors: Darsh Gautam Vinay Pandit Sanjay Kumar Poonam Talwan Tarun Sharma Source Type: research
Gold Nanoparticle-Based Drug Delivery System for the Diagnosis and Treatment of Bacterial Meningitis
Curr Drug Deliv. 2024 Apr 16. doi: 10.2174/0115672018278607240405060054. Online ahead of print.ABSTRACTManaging bacterial pathogens in the central nervous system is an immense issue for researchers all around the globe. The problem of these infections remains throughout the population, regardless of the discovery of several possible medicines. The major obstacle to drug delivery is the BBB, but only a few medicines that fulfill demanding requirements can penetrate it. Considering inadequate antibiotic alternatives and the increasing development of resistance, it is more important than ever to find new approaches to address...
Source: Current Drug Delivery - April 17, 2024 Category: Drugs & Pharmacology Authors: Darsh Gautam Vinay Pandit Sanjay Kumar Poonam Talwan Tarun Sharma Source Type: research
An Epic Advancement in Targeting Macrophages for Cancer Therapy Approach
Curr Drug Deliv. 2024 Apr 8. doi: 10.2174/0115672018299798240403062508. Online ahead of print.ABSTRACTMacrophages are immune cells with high heterogeneity and plasticity, crucial for recognizing and eliminating foreign substances, including cancer cells. However, cancer cells can evade the immune system by producing signals that cause macrophages to switch to a pro-tumor phenotype, promoting tumor growth and progression. Tumor-associated macrophages, which infiltrate into tumor tissue, are important immune cells in the tumor microenvironment and can regulate cancer's growth, invasion, and metastasis by inhibiting tumor imm...
Source: Current Drug Delivery - April 9, 2024 Category: Drugs & Pharmacology Authors: Lu Xiaohong Fu Qiuxia Li Ruie Wang Daijie Tobias Achu Muluh Yan Zhang Source Type: research
An Epic Advancement in Targeting Macrophages for Cancer Therapy Approach
Curr Drug Deliv. 2024 Apr 8. doi: 10.2174/0115672018299798240403062508. Online ahead of print.ABSTRACTMacrophages are immune cells with high heterogeneity and plasticity, crucial for recognizing and eliminating foreign substances, including cancer cells. However, cancer cells can evade the immune system by producing signals that cause macrophages to switch to a pro-tumor phenotype, promoting tumor growth and progression. Tumor-associated macrophages, which infiltrate into tumor tissue, are important immune cells in the tumor microenvironment and can regulate cancer's growth, invasion, and metastasis by inhibiting tumor imm...
Source: Current Drug Delivery - April 9, 2024 Category: Drugs & Pharmacology Authors: Lu Xiaohong Fu Qiuxia Li Ruie Wang Daijie Tobias Achu Muluh Yan Zhang Source Type: research
An Epic Advancement in Targeting Macrophages for Cancer Therapy Approach
Curr Drug Deliv. 2024 Apr 8. doi: 10.2174/0115672018299798240403062508. Online ahead of print.ABSTRACTMacrophages are immune cells with high heterogeneity and plasticity, crucial for recognizing and eliminating foreign substances, including cancer cells. However, cancer cells can evade the immune system by producing signals that cause macrophages to switch to a pro-tumor phenotype, promoting tumor growth and progression. Tumor-associated macrophages, which infiltrate into tumor tissue, are important immune cells in the tumor microenvironment and can regulate cancer's growth, invasion, and metastasis by inhibiting tumor imm...
Source: Current Drug Delivery - April 9, 2024 Category: Drugs & Pharmacology Authors: Lu Xiaohong Fu Qiuxia Li Ruie Wang Daijie Tobias Achu Muluh Yan Zhang Source Type: research
An Epic Advancement in Targeting Macrophages for Cancer Therapy Approach
Curr Drug Deliv. 2024 Apr 8. doi: 10.2174/0115672018299798240403062508. Online ahead of print.ABSTRACTMacrophages are immune cells with high heterogeneity and plasticity, crucial for recognizing and eliminating foreign substances, including cancer cells. However, cancer cells can evade the immune system by producing signals that cause macrophages to switch to a pro-tumor phenotype, promoting tumor growth and progression. Tumor-associated macrophages, which infiltrate into tumor tissue, are important immune cells in the tumor microenvironment and can regulate cancer's growth, invasion, and metastasis by inhibiting tumor imm...
Source: Current Drug Delivery - April 9, 2024 Category: Drugs & Pharmacology Authors: Lu Xiaohong Fu Qiuxia Li Ruie Wang Daijie Tobias Achu Muluh Yan Zhang Source Type: research
An Epic Advancement in Targeting Macrophages for Cancer Therapy Approach
Curr Drug Deliv. 2024 Apr 8. doi: 10.2174/0115672018299798240403062508. Online ahead of print.ABSTRACTMacrophages are immune cells with high heterogeneity and plasticity, crucial for recognizing and eliminating foreign substances, including cancer cells. However, cancer cells can evade the immune system by producing signals that cause macrophages to switch to a pro-tumor phenotype, promoting tumor growth and progression. Tumor-associated macrophages, which infiltrate into tumor tissue, are important immune cells in the tumor microenvironment and can regulate cancer's growth, invasion, and metastasis by inhibiting tumor imm...
Source: Current Drug Delivery - April 9, 2024 Category: Drugs & Pharmacology Authors: Lu Xiaohong Fu Qiuxia Li Ruie Wang Daijie Tobias Achu Muluh Yan Zhang Source Type: research
An Epic Advancement in Targeting Macrophages for Cancer Therapy Approach
Curr Drug Deliv. 2024 Apr 8. doi: 10.2174/0115672018299798240403062508. Online ahead of print.ABSTRACTMacrophages are immune cells with high heterogeneity and plasticity, crucial for recognizing and eliminating foreign substances, including cancer cells. However, cancer cells can evade the immune system by producing signals that cause macrophages to switch to a pro-tumor phenotype, promoting tumor growth and progression. Tumor-associated macrophages, which infiltrate into tumor tissue, are important immune cells in the tumor microenvironment and can regulate cancer's growth, invasion, and metastasis by inhibiting tumor imm...
Source: Current Drug Delivery - April 9, 2024 Category: Drugs & Pharmacology Authors: Lu Xiaohong Fu Qiuxia Li Ruie Wang Daijie Tobias Achu Muluh Yan Zhang Source Type: research
Resveratrol-based Delivery Systems as Contemporary Nominees for Combating Pulmonary Diseases: A Comprehensive Review
Curr Drug Deliv. 2024 Feb 16. doi: 10.2174/0115672018265986240209064358. Online ahead of print.ABSTRACTExploiting different formulation approaches, each designed to improve the clinical use of resveratrol (RES) in treating several lung diseases. Accentuating the rationale for using RESbased delivery systems in different clinical applications in pulmonary diseases. Resveratrol (RES), a well-known natural polyphenol stilbenoid, possesses tremendous potential to treat various lung diseases owing to its anti-inflammatory, antioxidant, antiapoptotic, antiviral, and anticancer activities. Its physicochemical properties have rest...
Source: Current Drug Delivery - March 29, 2024 Category: Drugs & Pharmacology Authors: Sara Ahmed Mai Mansour Rania A H Ishak Nahed D Mortada Source Type: research
Resveratrol-based Delivery Systems as Contemporary Nominees for Combating Pulmonary Diseases: A Comprehensive Review
Curr Drug Deliv. 2024 Feb 16. doi: 10.2174/0115672018265986240209064358. Online ahead of print.ABSTRACTExploiting different formulation approaches, each designed to improve the clinical use of resveratrol (RES) in treating several lung diseases. Accentuating the rationale for using RESbased delivery systems in different clinical applications in pulmonary diseases. Resveratrol (RES), a well-known natural polyphenol stilbenoid, possesses tremendous potential to treat various lung diseases owing to its anti-inflammatory, antioxidant, antiapoptotic, antiviral, and anticancer activities. Its physicochemical properties have rest...
Source: Current Drug Delivery - March 29, 2024 Category: Drugs & Pharmacology Authors: Sara Ahmed Mai Mansour Rania A H Ishak Nahed D Mortada Source Type: research
Resveratrol-based Delivery Systems as Contemporary Nominees for Combating Pulmonary Diseases: A Comprehensive Review
Curr Drug Deliv. 2024 Feb 16. doi: 10.2174/0115672018265986240209064358. Online ahead of print.ABSTRACTExploiting different formulation approaches, each designed to improve the clinical use of resveratrol (RES) in treating several lung diseases. Accentuating the rationale for using RESbased delivery systems in different clinical applications in pulmonary diseases. Resveratrol (RES), a well-known natural polyphenol stilbenoid, possesses tremendous potential to treat various lung diseases owing to its anti-inflammatory, antioxidant, antiapoptotic, antiviral, and anticancer activities. Its physicochemical properties have rest...
Source: Current Drug Delivery - March 29, 2024 Category: Drugs & Pharmacology Authors: Sara Ahmed Mai Mansour Rania A H Ishak Nahed D Mortada Source Type: research
Resveratrol-based Delivery Systems as Contemporary Nominees for Combating Pulmonary Diseases: A Comprehensive Review
Curr Drug Deliv. 2024 Feb 16. doi: 10.2174/0115672018265986240209064358. Online ahead of print.ABSTRACTExploiting different formulation approaches, each designed to improve the clinical use of resveratrol (RES) in treating several lung diseases. Accentuating the rationale for using RESbased delivery systems in different clinical applications in pulmonary diseases. Resveratrol (RES), a well-known natural polyphenol stilbenoid, possesses tremendous potential to treat various lung diseases owing to its anti-inflammatory, antioxidant, antiapoptotic, antiviral, and anticancer activities. Its physicochemical properties have rest...
Source: Current Drug Delivery - March 29, 2024 Category: Drugs & Pharmacology Authors: Sara Ahmed Mai Mansour Rania A H Ishak Nahed D Mortada Source Type: research
Resveratrol-based Delivery Systems as Contemporary Nominees for Combating Pulmonary Diseases: A Comprehensive Review
Curr Drug Deliv. 2024 Feb 16. doi: 10.2174/0115672018265986240209064358. Online ahead of print.ABSTRACTExploiting different formulation approaches, each designed to improve the clinical use of resveratrol (RES) in treating several lung diseases. Accentuating the rationale for using RESbased delivery systems in different clinical applications in pulmonary diseases. Resveratrol (RES), a well-known natural polyphenol stilbenoid, possesses tremendous potential to treat various lung diseases owing to its anti-inflammatory, antioxidant, antiapoptotic, antiviral, and anticancer activities. Its physicochemical properties have rest...
Source: Current Drug Delivery - March 29, 2024 Category: Drugs & Pharmacology Authors: Sara Ahmed Mai Mansour Rania A H Ishak Nahed D Mortada Source Type: research
Resveratrol-based Delivery Systems as Contemporary Nominees for Combating Pulmonary Diseases: A Comprehensive Review
Curr Drug Deliv. 2024 Feb 16. doi: 10.2174/0115672018265986240209064358. Online ahead of print.ABSTRACTExploiting different formulation approaches, each designed to improve the clinical use of resveratrol (RES) in treating several lung diseases. Accentuating the rationale for using RESbased delivery systems in different clinical applications in pulmonary diseases. Resveratrol (RES), a well-known natural polyphenol stilbenoid, possesses tremendous potential to treat various lung diseases owing to its anti-inflammatory, antioxidant, antiapoptotic, antiviral, and anticancer activities. Its physicochemical properties have rest...
Source: Current Drug Delivery - March 29, 2024 Category: Drugs & Pharmacology Authors: Sara Ahmed Mai Mansour Rania A H Ishak Nahed D Mortada Source Type: research
