Wound Dressing Detects Infection, Changes Color
Researchers at Linköping University in Sweden created a wound dressing that can provide a visual indication if the underlying wound is infected. Chronic wounds are difficult to manage, and presently healthcare staff must remove the dressing regularly to check if an infection is developing. However, this can disrupt the wound by damaging the scab, impairing healing, and may even introduce pathogens in the process. This latest technology takes advantage of the tendency of infected wounds to show a reduction in acidity and become more basic. It consists of a nitrocellulose dressing that contains mesoporous silica nanoparticl...
Source: Medgadget - May 1, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Dermatology Materials Military Medicine Surgery liu_universitet Source Type: blogs
Fight Aging! Newsletter, February 7th 2022
In this study, we used accelerometer measurements (1) to examine the association of physical activity and mortality in a population-based sample of US adults and (2) to estimate the number of deaths prevented annually with modest increases in moderate-to-vigorous physical activity (MVPA) intensity.
This analysis included 4,840 participants. Increasing MVPA by 10, 20, or 30 minutes per day was associated with a 6.9%, 13.0%, and 16.9% decrease in the number of deaths per year, respectively. We estimated that approximately 110,000 deaths per year could be prevented if US adults aged 40 to 85 years or older increased th...
Source: Fight Aging! - February 6, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Laser Kills Multidrug-Resistant Bacteria for Wound and Blood Decontamination
Scientists at Washington University School of Medicine in St. Louis have developed an ultrashort-pulse laser that can kill multidrug-resistant bacteria and their spores, and without damaging human cells. The laser works by vibrating and breaking protein structures within the bacterial cell, resulting in biochemical disruption and eventual death. The researchers hope that the technique could prove useful in decontaminating wounds and blood products.
Killing multidrug-resistant bacteria is no mean feat, as many of the common antibiotics we use are no longer effective against them. General antibacterial strategies that cou...
Source: Medgadget - November 29, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Military Medicine Plastic Surgery Source Type: blogs
Simple Color Change Test Identifies Wound Infections
Researchers at the University of Bath in the UK, along with outside collaborators, have developed a simple color change test that rapidly indicates whether a wound is infected with harmful bacteria. The test works by detecting virulence factors released by the bacteria, which prompt a simple color change in a solution. The test could help clinicians to determine whether to prescribe antibiotics, and may help to avoid unnecessary prescribing. As the test can be administered at the point of care, and does not require expensive and time-consuming laboratory analysis, it may be very useful in low-resource or remote regions.
...
Source: Medgadget - November 5, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Dermatology Diagnostics Materials Plastic Surgery uniofbath wound care Source Type: blogs
Rapid Identification of Antibiotic-Resistant Infections: Interview with Jong Lee, CEO at Day Zero Diagnostics
Antibiotic resistance is a growing concern, with some predictions suggesting that routine surgery could be unacceptably risky in a future where many antibiotics have become obsolete. Part of the problem lies in the time it takes clinicians to diagnose an antibiotic-resistant infection. Current techniques involve lab technicians culturing a bacterial sample until it can be analyzed for drug resistance. The whole process takes days, and by the time the test provides an answer, a patient could be dead from sepsis.
To address this, clinicians typically administer broad-spectrum antibiotics in an effort to bring an infection...
Source: Medgadget - November 11, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Medicine Pathology Public Health Source Type: blogs
Fight Aging! Newsletter, January 20th 2020
This study provides strong evidence that following a healthy lifestyle can substantially extend the years a person lives disease-free."
Commentary on Recent Evidence for Cognitive Decline to Precede Amyloid Aggregation in Alzheimer's Disease
https://www.fightaging.org/archives/2020/01/commentary-on-recent-evidence-for-cognitive-decline-to-precede-amyloid-aggregation-in-alzheimers-disease/
I can't say that I think the data presented in the research noted here merits quite the degree of the attention that it has been given in the popular science press. It is interesting, but not compelling if its role is ...
Source: Fight Aging! - January 19, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Transplantation of Engineered Macrophages Rescues Mice from Sepsis
In this study, researchers collected monocytes from the bone marrow of healthy mice and cultured them in conditions that transformed them into macrophages. The lab also developed vitamin-based nanoparticles that were especially good at delivering messenger RNA, molecules that translate genetic information into functional proteins.
The scientists, who specialize in messenger RNA for therapeutic purposes, constructed a messenger RNA encoding an antimicrobial peptide and a signal protein. The signal protein enabled the specific accumulation of the antimicrobial peptide in internal macrophage structures called lysosomes...
Source: Fight Aging! - January 13, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Liver Chip Avoids Animal Testing, Makes Drug Research Easier, Faster
Low liver toxicity is a major hurdle that drug candidates have to demonstrate before they are used as therapeutic medications. This testing is usually performed using animals, including rodents and dogs, with livers that aren’t quite like ours. Animal studies are useful, but they often result in misleading information, which may not be realized until long into the drug development process. Sometimes, patients are injured by such drug candidates when liver toxicity isn’t properly assessed ahead of time.
Now, a research collaboration involving scientists from Emulate, a Boston-based firm, AstraZeneca, Janssen ...
Source: Medgadget - December 5, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Materials Medicine Source Type: blogs
What to know about C. auris, the deadly fungus affecting our sickest patients
Candida auris (C. auris) is a multidrug-resistant fungus responsible for a rising number of infections and deaths around the world, the origin of which is currently subject to investigation. Spread primarily in the health care setting, it is a growing threat to high-risk patients in hospitals, nursing homes, an d other health care facilities. The CDC estimates […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 7, 2019 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/gerald-blackburn" rel="tag" > Gerald Blackburn, DO < /a > < /span > Tags: Conditions Infectious Disease Source Type: blogs
Antibiotic effect of ticagrelor
Ticagrelor is a reversible platelet adenosine diphosphate P2Y12 receptor (P2Y12) inhibitor and is quite effective as an antiplatelet agent. New research suggests an antibiotic effect for ticagrelor and the researchers suggest that further research may lead to development of a new class of antibiotics [1]. In fact there is a global need for new antibiotics, which are conspicuous by their absence in the current scenario of multidrug resistant organisms. The study published as a Research Letter in JAMA Cardiology reports on the ‘Antibacterial Activity of Ticagrelor in Conventional Antiplatelet Dosages Against Antibi...
Source: Cardiophile MD - May 20, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs
Stalking the wild garganey in West Sacramento #birding #eBird #iNaturalist #birdphotography #nikonD500
So - I did a thing today. A new thing for me. I officially became a bird nut. For the first time in my life, I went on an outing to see a rare bird that I read about online.I went to West Sacramento, to a pond there, to see, and hopefully take pictures of, a garganey. What, you ask, is a garganey? It is a kind of duck. According to Wikipedia:The garganey (Spatula querquedula) is a small dabbling duck. It breeds in much of Europe and western Asia, but is strictly migratory, with the entire population moving to southern Africa, India (in particular Santragachi), Banglade...
Source: The Tree of Life - March 9, 2019 Category: Microbiology Authors: Jonathan Eisen Source Type: blogs
Superbugs and Superdrugs Conference
March 18 - 19, 2019 Superbugs and Superdrugs Conference London, UK Inspiring the global commitment required to tackle multidrug-resistance among bacteria populations, as the global threat of antimicrobial resistance continues to grow. This year's event will gather leaders from pharmaceutical companies, academia and the wider scientific community together with regulatory agencies and public-private partnerships, to discuss the growing threat of antibiotic resistance. Further information (Source: Microbiology Blog: The weblog for microbiologists.)
Source: Microbiology Blog: The weblog for microbiologists. - October 19, 2018 Category: Microbiology Source Type: blogs
Scientists Create Maps of Gonorrhea ’s Resistance to Antibiotics
A team of European researchers has mapped the genome of various strains of gonorrhea, creating a way to identify antibiotic resistance before trying different regimens of antibiotics.
By sequencing DNA gathered from patient samples, the researchers were able to spot individual cases of resistance and to correct faulty lab test results.
While important in itself, the research points to more evidence that genomic testing is revolutionizing medicine in a variety of ways.
Open access study in The Lancet Infectious Diseases: Public health surveillance of multidrug-resistant clones of Neisseria gonorrhoeae in Europe: a genomic s...
Source: Medgadget - May 17, 2018 Category: Medical Devices Authors: Editors Tags: Genetics Medicine Public Health Source Type: blogs
Superbugs and Superdrugs 2018
Superbugs and Superdrugs 2018London, UK March 19 - 20, 2018 Further informationThe 20th Annual Superbugs and Superdrugs Conference Leaders from pharmaceutical companies, academia and the wider scientific community together with regulatory agencies and public-private partnerships gather to discuss the growing threat of antibiotic resistance and multidrug-resistant bacteria. The conference will cover strategies to support antimicrobial resistance research and development, latest scientific advancements for tackling antimicrobial resistance and the potential novel candidates and alternatives to anti-microbials. ...
Source: Microbiology Blog: The weblog for microbiologists. - November 10, 2017 Category: Microbiology Source Type: blogs
